Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Roni Nowarski, Ph.D.

Title
Institution
Department
Address
Phone
Profile Picture
Other Positions
Title
Institution
Department

Biography
Yale School of MedicineImmunology

Overview
Our laboratory studies the immune signaling pathways that regulate tissue inflammation, and the mechanistic basis for tissue pathology in inflammatory and autoimmune disorders

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jarret A, Jackson R, Duizer C, Healy ME, Zhao J, Rone JM, Bielecki P, Sefik E, Roulis M, Rice T, Sivanathan KN, Zhou T, Solis AG, Honcharova-Biletska H, Vélez K, Hartner S, Low JS, Qu R, de Zoete MR, Palm NW, Ring AM, Weber A, Moor AE, Kluger Y, Nowarski R, Flavell RA. Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity. Cell. 2020 Feb 20; 180(4):813-814. PMID: 32084342.
    Citations: 5     Fields:    
  2. Jarret A, Jackson R, Duizer C, Healy ME, Zhao J, Rone JM, Bielecki P, Sefik E, Roulis M, Rice T, Sivanathan KN, Zhou T, Solis AG, Honcharova-Biletska H, Vélez K, Hartner S, Low JS, Qu R, de Zoete MR, Palm NW, Ring AM, Weber A, Moor AE, Kluger Y, Nowarski R, Flavell RA. Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity. Cell. 2020 01 09; 180(1):50-63.e12. PMID: 31923399.
    Citations: 11     Fields:    Translation:AnimalsCells
  3. Lai NY, Musser MA, Pinho-Ribeiro FA, Baral P, Jacobson A, Ma P, Potts DE, Chen Z, Paik D, Soualhi S, Yan Y, Misra A, Goldstein K, Lagomarsino VN, Nordstrom A, Sivanathan KN, Wallrapp A, Kuchroo VK, Nowarski R, Starnbach MN, Shi H, Surana NK, An D, Wu C, Huh JR, Rao M, Chiu IM, Chiu IM. Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. Cell. 2020 01 09; 180(1):33-49.e22. PMID: 31813624.
    Citations: 36     Fields:    Translation:AnimalsCells
  4. Nowarski R, Jackson R, Flavell RA. The Stromal Intervention: Regulation of Immunity and Inflammation at the Epithelial-Mesenchymal Barrier. Cell. 2017 01 26; 168(3):362-375. PMID: 28129537.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  5. Nowarski R, Jackson R, Gagliani N, de Zoete MR, Palm NW, Bailis W, Low JS, Harman CC, Graham M, Elinav E, Flavell RA. Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis. Cell. 2015 Dec 03; 163(6):1444-56. PMID: 26638073.
    Citations: 110     Fields:    Translation:AnimalsCells
  6. Nowarski R, Prabhu P, Kenig E, Smith Y, Britan-Rosich E, Kotler M. APOBEC3G inhibits HIV-1 RNA elongation by inactivating the viral trans-activation response element. J Mol Biol. 2014 Jul 29; 426(15):2840-53. PMID: 24859335.
    Citations: 9     Fields:    Translation:HumansCells
  7. Wlodarska M, Thaiss CA, Nowarski R, Henao-Mejia J, Zhang JP, Brown EM, Frankel G, Levy M, Katz MN, Philbrick WM, Elinav E, Finlay BB, Flavell RA. NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion. Cell. 2014 Feb 27; 156(5):1045-59. PMID: 24581500.
    Citations: 218     Fields:    Translation:AnimalsCells
  8. Elinav E, Nowarski R, Thaiss CA, Hu B, Jin C, Flavell RA. Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nat Rev Cancer. 2013 Nov; 13(11):759-71. PMID: 24154716.
    Citations: 526     Fields:    Translation:HumansAnimalsCells
  9. Nowarski R, Gagliani N, Huber S, Flavell RA. Innate immune cells in inflammation and cancer. Cancer Immunol Res. 2013 Aug; 1(2):77-84. PMID: 24777498.
    Citations: 40     Fields:    Translation:HumansCells
  10. Nowarski R, Kotler M. APOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotion. Cancer Res. 2013 Jun 15; 73(12):3494-8. PMID: 23598277.
    Citations: 21     Fields:    Translation:HumansCells
  11. Nowarski R, Wilner OI, Cheshin O, Shahar OD, Kenig E, Baraz L, Britan-Rosich E, Nagler A, Harris RS, Goldberg M, Willner I, Kotler M. APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair. Blood. 2012 Jul 12; 120(2):366-75. PMID: 22645179.
    Citations: 31     Fields:    Translation:HumansCells
  12. Britan-Rosich E, Nowarski R, Kotler M. Multifaceted counter-APOBEC3G mechanisms employed by HIV-1 Vif. J Mol Biol. 2011 Jul 29; 410(5):1065-76. PMID: 21763507.
    Citations: 21     Fields:    Translation:HumansCells
  13. Cadima-Couto I, Freitas-Vieira A, Nowarski R, Britan-Rosich E, Kotler M, Goncalves J. Ubiquitin-fusion as a strategy to modulate protein half-life: A3G antiviral activity revisited. Virology. 2009 Oct 25; 393(2):286-94. PMID: 19717177.
    Citations: 1     Fields:    Translation:HumansCells
  14. Harjes E, Gross PJ, Chen KM, Lu Y, Shindo K, Nowarski R, Gross JD, Kotler M, Harris RS, Matsuo H. An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model. J Mol Biol. 2009 Jun 26; 389(5):819-32. PMID: 19389408.
    Citations: 76     Fields:    Translation:HumansCells
  15. Nowarski R, Britan-Rosich E, Shiloach T, Kotler M. Hypermutation by intersegmental transfer of APOBEC3G cytidine deaminase. Nat Struct Mol Biol. 2008 Oct; 15(10):1059-66. PMID: 18820687.
    Citations: 67     Fields:    Translation:HumansCells
  16. Shlyahovsky B, Li D, Weizmann Y, Nowarski R, Kotler M, Willner I. Spotlighting of cocaine by an autonomous aptamer-based machine. J Am Chem Soc. 2007 Apr 04; 129(13):3814-5. PMID: 17352479.
    Citations: 23     Fields:    Translation:Cells
  17. Weizmann Y, Beissenhirtz MK, Cheglakov Z, Nowarski R, Kotler M, Willner I. A virus spotlighted by an autonomous DNA machine. Angew Chem Int Ed Engl. 2006 Nov 13; 45(44):7384-8. PMID: 17036292.
    Citations: 17     Fields:    Translation:Cells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Nowarski's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (114)
Explore
_
Co-Authors (12)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.