Harvard Catalyst Profiles

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Michael Klompas, M.D.

Co-Author

This page shows the publications co-authored by Michael Klompas and Chanu Rhee.
Connection Strength

24.327
  1. Klompas M, Baker MA, Rhee C. Airborne Transmission of SARS-CoV-2: Theoretical Considerations and Available Evidence. JAMA. 2020 Jul 13.
    View in: PubMed
    Score: 0.987
  2. Rhee C, Li Z, Wang R, Song Y, Kadri SS, Septimus EJ, Chen HC, Fram D, Jin R, Poland R, Sands K, Klompas M. Impact of Risk Adjustment Using Clinical vs Administrative Data on Hospital Sepsis Mortality Comparisons. Open Forum Infect Dis. 2020 Jun; 7(6):ofaa213.
    View in: PubMed
    Score: 0.983
  3. Klompas M, Rhee C. Current Sepsis Mandates Are Overly Prescriptive, and Some Aspects May Be Harmful. Crit Care Med. 2020 Jun; 48(6):890-893.
    View in: PubMed
    Score: 0.979
  4. Rhee C, Baker MA, Klompas M. The COVID-19 infection control arms race. Infect Control Hosp Epidemiol. 2020 May 08; 1-3.
    View in: PubMed
    Score: 0.975
  5. Rhee C, Chiotos K, Cosgrove SE, Heil EL, Kadri SS, Kalil AC, Gilbert DN, Masur H, Septimus EJ, Sweeney DA, Strich JR, Winslow DL, Klompas M. Infectious Diseases Society of America Position Paper: Recommended Revisions to the National Severe Sepsis and Septic Shock Early Management Bundle (SEP-1) Sepsis Quality Measure. Clin Infect Dis. 2020 May 06.
    View in: PubMed
    Score: 0.974
  6. Rhee C, Klompas M. The Eye-Popping Costs Associated With Sepsis Diagnoses Among Medicare Beneficiaries. Crit Care Med. 2020 Mar; 48(3):420-422.
    View in: PubMed
    Score: 0.962
  7. Rhee C, Klompas M. Sepsis trends: increasing incidence and decreasing mortality, or changing denominator? J Thorac Dis. 2020 Feb; 12(Suppl 1):S89-S100.
    View in: PubMed
    Score: 0.957
  8. Klompas M, Osborn TM, Rhee C. Who Owns Sepsis? Ann Intern Med. 2020 02 04; 172(3):210-211.
    View in: PubMed
    Score: 0.956
  9. Rhee C, Wang R, Song Y, Zhang Z, Kadri SS, Septimus EJ, Fram D, Jin R, Poland RE, Hickok J, Sands K, Klompas M. Risk Adjustment for Sepsis Mortality to Facilitate Hospital Comparisons Using Centers for Disease Control and Prevention's Adult Sepsis Event Criteria and Routine Electronic Clinical Data. Crit Care Explor. 2019 Oct; 1(10):e0049.
    View in: PubMed
    Score: 0.937
  10. Klompas M, Rhee C. Antibiotic Order-to-Infusion Time for Patients With Septic Shock: A Potential New Quality Metric. Crit Care Med. 2019 10; 47(10):1467-1470.
    View in: PubMed
    Score: 0.935
  11. Rhee C, Klompas M. The authors reply. Crit Care Med. 2019 08; 47(8):e718.
    View in: PubMed
    Score: 0.924
  12. Rhee C, Dantes RB, Epstein L, Klompas M. Using objective clinical data to track progress on preventing and treating sepsis: CDC's new 'Adult Sepsis Event' surveillance strategy. BMJ Qual Saf. 2019 04; 28(4):305-309.
    View in: PubMed
    Score: 0.871
  13. Klompas M, Rhee C. Missed Opportunities for Better Sepsis Care or Misplaced Blame? Deconstructing Patients' Encounters in the Week Before Sepsis Hospitalizations. Crit Care Med. 2018 04; 46(4):644-645.
    View in: PubMed
    Score: 0.842
  14. Rhee C, Klompas M. What Is the National Burden of Sepsis in U.S. Emergency Departments? It Depends on the Definition. Crit Care Med. 2017 09; 45(9):1569-1571.
    View in: PubMed
    Score: 0.809
  15. Rhee C, Klompas M. New Sepsis and Septic Shock Definitions: Clinical Implications and Controversies. Infect Dis Clin North Am. 2017 09; 31(3):397-413.
    View in: PubMed
    Score: 0.800
  16. Klompas M, Rhee C. Sepsis and the theory of relativity: measuring a moving target with a moving measuring stick. Crit Care. 2016 11 21; 20(1):396.
    View in: PubMed
    Score: 0.767
  17. Klompas M, Rhee C. We Need Better Tools for Sepsis Surveillance. Crit Care Med. 2016 07; 44(7):1441-2.
    View in: PubMed
    Score: 0.746
  18. Klompas M, Rhee C. The CMS Sepsis Mandate: Right Disease, Wrong Measure. Ann Intern Med. 2016 Oct 04; 165(7):517-518.
    View in: PubMed
    Score: 0.744
  19. Rhee C, Kadri SS, Danner RL, Suffredini AF, Massaro AF, Kitch BT, Lee G, Klompas M. Diagnosing sepsis is subjective and highly variable: a survey of intensivists using case vignettes. Crit Care. 2016 Apr 06; 20:89.
    View in: PubMed
    Score: 0.734
  20. Rhee C, Kadri S, Huang SS, Murphy MV, Li L, Platt R, Klompas M. Objective Sepsis Surveillance Using Electronic Clinical Data. Infect Control Hosp Epidemiol. 2016 Feb; 37(2):163-71.
    View in: PubMed
    Score: 0.713
  21. Rhee C, Gohil S, Klompas M. Regulatory mandates for sepsis care--reasons for caution. N Engl J Med. 2014 May 01; 370(18):1673-6.
    View in: PubMed
    Score: 0.640
  22. Shappell CN, Klompas M, Rhee C. Does Severe Acute Respiratory Syndrome Coronavirus 2 Cause Sepsis? Crit Care Med. 2020 Aug 24.
    View in: PubMed
    Score: 0.249
  23. Shappell CN, Klompas M, Rhee C. Surveillance Strategies for Tracking Sepsis Incidence and Outcomes. J Infect Dis. 2020 Jul 21; 222(Supplement_2):S74-S83.
    View in: PubMed
    Score: 0.247
  24. Weinberger J, Rhee C, Klompas M. A Critical Analysis of the Literature on Time-to-Antibiotics in Suspected Sepsis. J Infect Dis. 2020 Jul 21; 222(Supplement_2):S110-S118.
    View in: PubMed
    Score: 0.247
  25. Klompas M, Ochoa A, Ji W, McKenna C, Clark R, Shenoy ES, Hooper D, Rhee C. Prevalence of Clinical Signs Within Reference Ranges Among Hospitalized Patients Prescribed Antibiotics for Pneumonia. JAMA Netw Open. 2020 Jul 01; 3(7):e2010700.
    View in: PubMed
    Score: 0.246
  26. Rhee C, Strich JR, Klompas M, Yealy DM, Masur H. SEP-1 Has Brought Much Needed Attention to Improving Sepsis Care…But Now Is the Time to Improve SEP-1. Crit Care Med. 2020 Jun; 48(6):779-782.
    View in: PubMed
    Score: 0.245
  27. Baker MA, Rhee C, Fiumara K, Bennett-Rizzo C, Tucker R, Williams SA, Wickner P, Beloff J, McGrath C, Poulton A, Klompas M. COVID-19 infections among HCWs exposed to a patient with a delayed diagnosis of COVID-19. Infect Control Hosp Epidemiol. 2020 May 27; 1-2.
    View in: PubMed
    Score: 0.245
  28. Rhee C, Kadri SS, Dekker JP, Danner RL, Chen HC, Fram D, Zhang F, Wang R, Klompas M. Prevalence of Antibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use. JAMA Netw Open. 2020 Apr 01; 3(4):e202899.
    View in: PubMed
    Score: 0.242
  29. Cooper AJ, Keller SP, Chan C, Glotzbecker BE, Klompas M, Baron RM, Rhee C. Improvements in Sepsis-associated Mortality in Hospitalized Patients with Cancer versus Those without Cancer. A 12-Year Analysis Using Clinical Data. Ann Am Thorac Soc. 2020 04; 17(4):466-473.
    View in: PubMed
    Score: 0.242
  30. Anand V, Klompas M, Rhee C. Response. Chest. 2020 01; 157(1):231-232.
    View in: PubMed
    Score: 0.238
  31. Anand V, Klompas M, Rhee C. Response. Chest. 2020 01; 157(1):233-234.
    View in: PubMed
    Score: 0.238
  32. Hsu HE, Abanyie F, Agus MSD, Balamuth F, Brady PW, Brilli RJ, Carcillo JA, Dantes R, Epstein L, Fiore AE, Gerber JS, Gokhale RH, Joyner BL, Kissoon N, Klompas M, Lee GM, Macias CG, Puopolo KM, Sulton CD, Weiss SL, Rhee C. A National Approach to Pediatric Sepsis Surveillance. Pediatrics. 2019 12; 144(6).
    View in: PubMed
    Score: 0.236
  33. Rhee C, Wang R, Zhang Z, Fram D, Kadri SS, Klompas M. Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality: A Retrospective Analysis Using Electronic Clinical Data. Crit Care Med. 2019 09; 47(9):1169-1176.
    View in: PubMed
    Score: 0.232
  34. Caroff DA, Menchaca JT, Zhang Z, Rhee C, Calderwood MS, Kubiak DW, Yokoe DS, Klompas M. Oral vancomycin prophylaxis during systemic antibiotic exposure to prevent Clostridiodes difficile infection relapses. Infect Control Hosp Epidemiol. 2019 06; 40(6):662-667.
    View in: PubMed
    Score: 0.227
  35. Rhee C, Jentzsch MS, Kadri SS, Seymour CW, Angus DC, Murphy DJ, Martin GS, Dantes RB, Epstein L, Fiore AE, Jernigan JA, Danner RL, Warren DK, Septimus EJ, Hickok J, Poland RE, Jin R, Fram D, Schaaf R, Wang R, Klompas M. Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons. Crit Care Med. 2019 04; 47(4):493-500.
    View in: PubMed
    Score: 0.226
  36. Rhee C, Zhang Z, Kadri SS, Murphy DJ, Martin GS, Overton E, Seymour CW, Angus DC, Dantes R, Epstein L, Fram D, Schaaf R, Wang R, Klompas M. Sepsis Surveillance Using Adult Sepsis Events Simplified eSOFA Criteria Versus Sepsis-3 Sequential Organ Failure Assessment Criteria. Crit Care Med. 2019 03; 47(3):307-314.
    View in: PubMed
    Score: 0.224
  37. Rhee C, Jones TM, Hamad Y, Pande A, Varon J, O'Brien C, Anderson DJ, Warren DK, Dantes RB, Epstein L, Klompas M. Prevalence, Underlying Causes, and Preventability of Sepsis-Associated Mortality in US Acute Care Hospitals. JAMA Netw Open. 2019 02 01; 2(2):e187571.
    View in: PubMed
    Score: 0.223
  38. Rhee C, Filbin MR, Massaro AF, Bulger AL, McEachern D, Tobin KA, Kitch BT, Thurlo-Walsh B, Kadar A, Koffman A, Pande A, Hamad Y, Warren DK, Jones TM, O'Brien C, Anderson DJ, Wang R, Klompas M. Compliance With the National SEP-1 Quality Measure and Association With Sepsis Outcomes: A Multicenter Retrospective Cohort Study. Crit Care Med. 2018 10; 46(10):1585-1591.
    View in: PubMed
    Score: 0.218
  39. Hume PS, Varon J, Englert JA, Hurwitz S, Klompas M, Baron RM, Rhee C. Trends in "usual care" for septic shock. Infect Control Hosp Epidemiol. 2018 09; 39(9):1125-1126.
    View in: PubMed
    Score: 0.215
  40. Rhee C, Brown SR, Jones TM, O'Brien C, Pande A, Hamad Y, Bulger AL, Tobin KA, Massaro AF, Anderson DJ, Warren DK, Klompas M. Variability in determining sepsis time zero and bundle compliance rates for the centers for medicare and medicaid services SEP-1 measure. Infect Control Hosp Epidemiol. 2018 08; 39(8):994-996.
    View in: PubMed
    Score: 0.214
  41. Rhee C, Dantes R, Epstein L, Murphy DJ, Seymour CW, Iwashyna TJ, Kadri SS, Angus DC, Danner RL, Fiore AE, Jernigan JA, Martin GS, Septimus E, Warren DK, Karcz A, Chan C, Menchaca JT, Wang R, Gruber S, Klompas M. Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014. JAMA. 2017 10 03; 318(13):1241-1249.
    View in: PubMed
    Score: 0.204
  42. Kadri SS, Rhee C, Strich JR, Morales MK, Hohmann S, Menchaca J, Suffredini AF, Danner RL, Klompas M. Estimating Ten-Year Trends in Septic Shock Incidence and Mortality in United States Academic Medical Centers Using Clinical Data. Chest. 2017 02; 151(2):278-285.
    View in: PubMed
    Score: 0.187
  43. Rhee C, Murphy MV, Li L, Platt R, Klompas M. Improving documentation and coding for acute organ dysfunction biases estimates of changing sepsis severity and burden: a retrospective study. Crit Care. 2015 Sep 14; 19:338.
    View in: PubMed
    Score: 0.177
  44. Rhee C, Murphy MV, Li L, Platt R, Klompas M. Lactate Testing in Suspected Sepsis: Trends and Predictors of Failure to Measure Levels. Crit Care Med. 2015 Aug; 43(8):1669-76.
    View in: PubMed
    Score: 0.175
  45. Rhee C, Klompas M, Tamburini FB, Fremin BJ, Chea N, Epstein L, Halpin AL, Guh A, Gallen R, Coulliette A, Gee J, Hsieh C, Desjardins CA, Pedamullu CS, DeAngelo DJ, Manzo VE, Folkerth RD, Milner DA, Pecora N, Osborne M, Chalifoux-Judge D, Bhatt AS, Yokoe DS. Epidemiologic Investigation of a Cluster of Neuroinvasive Bacillus cereus Infections in 5 Patients With Acute Myelogenous Leukemia. Open Forum Infect Dis. 2015 Sep; 2(3):ofv096.
    View in: PubMed
    Score: 0.174
  46. Rhee C, Murphy MV, Li L, Platt R, Klompas M. Comparison of trends in sepsis incidence and coding using administrative claims versus objective clinical data. Clin Infect Dis. 2015 Jan 01; 60(1):88-95.
    View in: PubMed
    Score: 0.165
  47. Baker MA, Fiumara K, Rhee C, Williams SA, Tucker R, Wickner P, Resnick A, Klompas M. Low risk of COVID-19 among patients exposed to infected healthcare workers. Clin Infect Dis. 2020 Aug 28.
    View in: PubMed
    Score: 0.062
  48. Fields AC, Vacanti JC, Rhee C, Klompas M, Kanjilal S, Maldonado L, Robinson MK, Nguyen LL, Pimentel MPT, Doherty GM, Bleday R. Restarting Essential Surgery in the Era of COVID-19: A Cautious Data Driven Approach Based on the Literature and Local Data. Ann Surg. 2020 May 22.
    View in: PubMed
    Score: 0.061
  49. Strich JR, Ricotta E, Warner S, Lai YL, Demirkale CY, Hohmann SF, Rhee C, Klompas M, Palmore T, Powers JH, Dekker JP, Adjemian J, Matsouaka R, Woods CW, Danner RL, Kadri SS. Pharmacoepidemiology of Ceftazidime-Avibactam Use: A Retrospective Cohort Analysis of 210 US Hospitals. Clin Infect Dis. 2020 Feb 28.
    View in: PubMed
    Score: 0.060
  50. Ji W, McKenna C, Ochoa A, Ramirez Batlle H, Young J, Zhang Z, Rhee C, Clark R, Shenoy ES, Hooper D, Klompas M. Development and Assessment of Objective Surveillance Definitions for Nonventilator Hospital-Acquired Pneumonia. JAMA Netw Open. 2019 10 02; 2(10):e1913674.
    View in: PubMed
    Score: 0.058
  51. Pepper DJ, Demirkale CY, Sun J, Rhee C, Fram D, Eichacker P, Klompas M, Suffredini AF, Kadri SS. Does Obesity Protect Against Death in Sepsis? A Retrospective Cohort Study of 55,038 Adult Patients. Crit Care Med. 2019 05; 47(5):643-650.
    View in: PubMed
    Score: 0.057
  52. Anand V, Zhang Z, Kadri SS, Klompas M, Rhee C. Epidemiology of Quick Sequential Organ Failure Assessment Criteria in Undifferentiated Patients and Association With Suspected Infection and Sepsis. Chest. 2019 08; 156(2):289-297.
    View in: PubMed
    Score: 0.057
  53. Kadri SS, Lai YLE, Ricotta EE, Strich JR, Babiker A, Rhee C, Klompas M, Dekker JP, Powers JH, Danner RL, Adjemian J. External Validation of Difficult-to-Treat Resistance Prevalence and Mortality Risk in Gram-Negative Bloodstream Infection Using Electronic Health Record Data From 140 US Hospitals. Open Forum Infect Dis. 2019 Apr; 6(4):ofz110.
    View in: PubMed
    Score: 0.056
  54. Kadri SS, Adjemian J, Lai YL, Spaulding AB, Ricotta E, Prevots DR, Palmore TN, Rhee C, Klompas M, Dekker JP, Powers JH, Suffredini AF, Hooper DC, Fridkin S, Danner RL. Difficult-to-Treat Resistance in Gram-negative Bacteremia at 173 US Hospitals: Retrospective Cohort Analysis of Prevalence, Predictors, and Outcome of Resistance to All First-line Agents. Clin Infect Dis. 2018 11 28; 67(12):1803-1814.
    View in: PubMed
    Score: 0.055
  55. Angus DC, Seymour CW, Coopersmith CM, Deutschman CS, Klompas M, Levy MM, Martin GS, Osborn TM, Rhee C, Watson RS. A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria. Crit Care Med. 2016 Mar; 44(3):e113-21.
    View in: PubMed
    Score: 0.046
  56. Seymour CW, Coopersmith CM, Deutschman CS, Gesten F, Klompas M, Levy M, Martin GS, Osborn TM, Rhee C, Warren DK, Watson RS, Angus DC. Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria. Crit Care Med. 2016 Mar; 44(3):e122-30.
    View in: PubMed
    Score: 0.046
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.