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Peter Ray Chai, M.D.

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Biography
Brown University, Providence, RIBA2006History of Art and Architecture
Brown University, Providence, RIMMS2007Artificial Organs, Biomaterials and Cellular Technology
Alpert Medical School at Brown University, Providence, RIMD2010Medicine
Rhode Island Hospital/Brown University, Providence, RI2014Emergency Medicine
University of Massachusetts Medical School, Worcester, MA2016Medical Toxicology

Overview
Research into behaviors surrounding ingestible and wearable biosensors that encompasses technology development, human factors testing and smartphone behavioral interventions to reinforce health. Focused mostly in HIV prevention, PrEP and sexual health.

Open student volunteer internship positions with ongoing projects at Brigham and Women's in emergency medicine and medical toxicology as well as PrEP research at Fenway Health.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. PCMS-CSV-G10BWH-2018-10290 (Peter Chai) Oct 1, 2018 - Dec 31, 2019
    Philips Biosensing
    Feasibility and Acceptability of wireless biometric monitoring using a novel wearable sensor
    Role Description: This grant investigates the operational barriers and usability of a novel wireless biosensor that collects real-time biometric data in emergency department patients.
    Role: Principal Investigator
  2. ISR-17-10189 (Peter Chai) Oct 1, 2018 - Oct 1, 2019
    Gilead Sciences
    Feasibility and Acceptability of Digital Pills to Monitor PrEP adherence in MSM with Substance Abuse (DigiPrEP)
    Role Description: This grant investigates the use of digital pills to measure real-time PrEP adherence in MSM with substance use disorders.
    Role: Principal Investigator
  3. K23DA044874 (CHAI, PETER R) Jun 1, 2018 - May 31, 2023
    NIH/NIDA
    Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users
    Role: Principal Investigator
  4. (Chai) May 31, 2016 - May 31, 2017
    Medical Toxicology Foundation
    Naloxone Distribution Patterns in Patients with a History of Heroin Abuse
    Role Description: This grant investigates advanced low energy Bluetooth technology to determine the penetrance of naloxone rescue kits distributed from the emergency department.
    Role: Primary Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chai PR, Pereira LM, Jambaulikar GD, Carrico AW, O'Cleirigh C, Mayer KH, Boyer EW. Short Communication: Bioequivalence of Tenofovir Component of Tenofovir/Rilpivirine/Emtricitabine in Digital Pills. AIDS Res Hum Retroviruses. 2019 Apr; 35(4):361-363. PMID: 30693811.
    Citations:    Fields:    
  2. Chai PR, Schreiber KL, Taylor SW, Jambaulikar GD, Kikut A, Hasdianda MA, Boyer EW. The Feasibility and Acceptability of a Smartphone-Based Music Intervention for Acute Pain. Proc Annu Hawaii Int Conf Syst Sci. 2019 Jan 08; 2019:3917-3925. PMID: 30700971.
    Citations:    
  3. Toce MS, Chai PR, Burns MM, Boyer EW. Pharmacologic Treatment of Opioid Use Disorder: a Review of Pharmacotherapy, Adjuncts, and Toxicity. J Med Toxicol. 2018 12; 14(4):306-322. PMID: 30377951.
    Citations:    Fields:    
  4. Jin H, Ogunbajo A, Mimiaga MJ, Duncan DT, Boyer E, Chai P, Dilworth SE, Carrico AW. Over the influence: The HIV care continuum among methamphetamine-using men who have sex with men. Drug Alcohol Depend. 2018 11 01; 192:125-128. PMID: 30248558.
    Citations:    Fields:    
  5. Chai PR, Carreiro S, Carey JL, Boyle KL, Chapman BP, Boyer EW. Faculty member writing groups support productivity. Clin Teach. 2018 Sep 07. PMID: 30256535.
    Citations:    Fields:    
  6. Chai PR, Zhang H, Baugh CW, Jambaulikar GD, McCabe JC, Gorman JM, Boyer EW, Landman A. Internet of Things Buttons for Real-Time Notifications in Hospital Operations: Proposal for Hospital Implementation. J Med Internet Res. 2018 08 10; 20(8):e251. PMID: 30097420.
    Citations:    Fields:    
  7. Nwanaji-Enwerem JC, Cardenas A, Chai PR, Weisskopf MG, Baccarelli AA, Boyer EW. Relationships of Long-term Smoking and Moist Snuff Consumption with a DNA Methylation Age Relevant Smoking Index: An Analysis in Buccal Cells. Nicotine Tob Res. 2018 Jul 21. PMID: 30053132.
    Citations:    Fields:    
  8. Chai PR, Hayes BD, Erickson TB, Boyer EW. Novichok agents: a historical, current, and toxicological perspective. Toxicol Commun. 2018; 2(1):45-48. PMID: 30003185.
    Citations:    
  9. Chai PR, Ruha AM, Wong KE, Monette DL, Spyres MB, Lapoint J, Greller H, Mycyk MB. The Virtual Toxicology Journal Club: the Dissemination and Discussion of Noteworthy Manuscripts Using Twitter. J Med Toxicol. 2018 09; 14(3):212-217. PMID: 29926389.
    Citations:    Fields:    
  10. Ouchi K, Lindvall C, Chai PR, Boyer EW. Machine Learning to Predict, Detect, and Intervene Older Adults Vulnerable for Adverse Drug Events in the Emergency Department. J Med Toxicol. 2018 09; 14(3):248-252. PMID: 29858745.
    Citations:    Fields:    
  11. Carreiro S, Chai PR, Carey J, Lai J, Smelson D, Boyer EW. mHealth for the Detection and Intervention in Adolescent and Young Adult Substance Use Disorder. Curr Addict Rep. 2018 Jun; 5(2):110-119. PMID: 30148037.
    Citations: 1     
  12. Broach J, Hart A, Griswold M, Lai J, Boyer EW, Skolnik AB, Chai PR. Usability and Reliability of Smart Glasses for Secondary Triage During Mass Casualty Incidents. Proc Annu Hawaii Int Conf Syst Sci. 2018 Jan 03; 2018:1416-1422. PMID: 29398976.
    Citations:    
  13. Lai JT, Chapman BP, Boyle KL, Boyer EW, Chai PR. Low-energy Bluetooth for detecting real-world penetrance of bystander naloxone kits: a pilot study. Proc Annu Hawaii Int Conf Syst Sci. 2018 Jan 03; 2018:3253-3258. PMID: 29416443.
    Citations:    
  14. Chai PR, Carreiro S, Innes BJ, Chapman B, Schreiber KL, Edwards RR, Carrico AW, Boyer EW. Oxycodone Ingestion Patterns in Acute Fracture Pain With Digital Pills. Anesth Analg. 2017 12; 125(6):2105-2112. PMID: 29189367.
    Citations:    Fields:    Translation:Humans
  15. Griswold MK, Chai PR, Krotulski AJ, Friscia M, Chapman BP, Varma N, Boyer EW, Logan BK, Babu KM. A Novel Oral Fluid Assay (LC-QTOF-MS) for the Detection of Fentanyl and Clandestine Opioids in Oral Fluid After Reported Heroin Overdose. J Med Toxicol. 2017 Dec; 13(4):287-292. PMID: 28971325.
    Citations:    Fields:    Translation:HumansPHPublic Health
  16. Chai PR, Boyer EW, Al-Nahhas H, Erickson TB. Toxic chemical weapons of assassination and warfare: nerve agents VX and sarin. Toxicol Commun. 2017; 1(1):21-23. PMID: 29974075.
    Citations: 1     
  17. Griswold MK, Chai PR, Krotulski AJ, Friscia M, Chapman B, Boyer EW, Logan BK, Babu KM. Self-identification of nonpharmaceutical fentanyl exposure following heroin overdose. Clin Toxicol (Phila). 2018 Jan; 56(1):37-42. PMID: 28681615.
    Citations:    Fields:    Translation:Humans
  18. Chai PR, Carreiro S, Ranney ML, Karanam K, Ahtisaari M, Edwards R, Schreiber KL, Ben-Ghaly L, Erickson TB, Boyer EW. Music as an Adjunct to Opioid-Based Analgesia. J Med Toxicol. 2017 Sep; 13(3):249-254. PMID: 28646359.
    Citations: 1     Fields:    Translation:Humans
  19. Griswold MK, Nordberg A, Babu KM, Boyer EW, Chai PR. Accidental copper sulfate toxicity after flame colorant ingestion. Clin Toxicol (Phila). 2017 09; 55(8):943-945. PMID: 28594239.
    Citations:    Fields:    
  20. Chai PR, Bonney C, Blohm E, Boyer EW, Babu KM. Canagliflozin-associated diabetic ketoacidosis: a case report. Toxicol Commun. 2017; 1(1):2-5. PMID: 29978156.
    Citations:    
  21. Carreiro S, Chai PR, Carey J, Chapman B, Boyer EW. Integrating Personalized Technology in Toxicology: Sensors, Smart Glass, and Social Media Applications in Toxicology Research. J Med Toxicol. 2017 06; 13(2):166-172. PMID: 28405896.
    Citations: 2     Fields:    Translation:Humans
  22. Chai PR, Carreiro S, Innes BJ, Rosen RK, O'Cleirigh C, Mayer KH, Boyer EW. Digital Pills to Measure Opioid Ingestion Patterns in Emergency Department Patients With Acute Fracture Pain: A Pilot Study. J Med Internet Res. 2017 01 13; 19(1):e19. PMID: 28087496.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  23. Carey JL, Nader N, Chai PR, Carreiro S, Griswold MK, Boyle KL. Drugs and Medical Devices: Adverse Events and the Impact on Women's Health. Clin Ther. 2017 Jan; 39(1):10-22. PMID: 28069260.
    Citations:    Fields:    Translation:Humans
  24. Hart A, Chai PR, Griswold MK, Lai JT, Boyer EW, Broach J. Acceptability and perceived utility of drone technology among emergency medical service responders and incident commanders for mass casualty incident management. Am J Disaster Med. 2017; 12(4):261-265. PMID: 29468628.
    Citations:    Fields:    Translation:Humans
  25. Skolnik AB, Chai PR, Dameff C, Gerkin R, Monas J, Padilla-Jones A, Curry S. Teletoxicology: Patient Assessment Using Wearable Audiovisual Streaming Technology. J Med Toxicol. 2016 12; 12(4):358-364. PMID: 27381429.
    Citations: 3     Fields:    Translation:Humans
  26. Chai PR. Wearable Devices and Biosensing: Future Frontiers. J Med Toxicol. 2016 12; 12(4):332-334. PMID: 27352082.
    Citations: 2     Fields:    Translation:Humans
  27. Chai PR, Hack JB. Intravenous lipid emulsion in the resuscitation of cocaine-induced cardiovascular arrest in a rat model. Am J Emerg Med. 2016 Aug; 34(8):1452-4. PMID: 27142757.
    Citations: 2     Fields:    Translation:Animals
  28. Chai PR, Rosen RK, Boyer EW. Ingestible Biosensors for Real-Time Medical Adherence Monitoring: MyTMed. Proc Annu Hawaii Int Conf Syst Sci. 2016 Jan; 2016:3416-3423. PMID: 27182206.
    Citations: 4     
  29. Chai PR, Castillo-Mancilla J, Buffkin E, Darling C, Rosen RK, Horvath KJ, Boudreaux ED, Robbins GK, Hibberd PL, Boyer EW. Utilizing an Ingestible Biosensor to Assess Real-Time Medication Adherence. J Med Toxicol. 2015 Dec; 11(4):439-44. PMID: 26245878.
    Citations: 7     Fields:    Translation:Humans
  30. Chai PR. Enriching the Toxicology Experience through Twitter. J Med Toxicol. 2015 Dec; 11(4):385-7. PMID: 26493395.
    Citations: 1     Fields:    Translation:Humans
  31. Chai PR, Babu KM, Boyer EW. The Feasibility and Acceptability of Google Glass for Teletoxicology Consults. J Med Toxicol. 2015 Sep; 11(3):283-7. PMID: 26245879.
    Citations: 8     Fields:    Translation:Humans
  32. Chai PR, Wu RY, Ranney ML, Bird J, Chai S, Zink B, Porter PS. Feasibility and Acceptability of Google Glass for Emergency Department Dermatology Consultations. JAMA Dermatol. 2015 Jul; 151(7):794-6. PMID: 25874898.
    Citations: 10     Fields:    Translation:Humans
  33. Chai PR, Wu RY, Ranney ML, Porter PS, Babu KM, Boyer EW. The virtual toxicology service: wearable head-mounted devices for medical toxicology. J Med Toxicol. 2014 Dec; 10(4):382-7. PMID: 25135308.
    Citations: 6     Fields:    Translation:Humans
  34. Chai P, Babu K. Toxin-induced coagulopathy. Emerg Med Clin North Am. 2014 Feb; 32(1):53-78. PMID: 24275169.
    Citations:    Fields:    Translation:Humans
  35. Chai PR, Bastan W, Machan J, Hack JB, Babu KM. Levamisole exposure and hematologic indices in cocaine users. Acad Emerg Med. 2011 Nov; 18(11):1141-7. PMID: 22092895.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  36. Ranney ML, Mello MJ, Baird JB, Chai PR, Clark MA. Correlates of motorcycle helmet use among recent graduates of a motorcycle training course. Accid Anal Prev. 2010 Nov; 42(6):2057-62. PMID: 20728662.
    Citations: 4     Fields:    Translation:Humans
  37. Rago AP, Chai PR, Morgan JR. Encapsulated arrays of self-assembled microtissues: an alternative to spherical microcapsules. Tissue Eng Part A. 2009 Feb; 15(2):387-95. PMID: 19193131.
    Citations: 9     Fields:    Translation:HumansCells
  38. Rago AP, Napolitano AP, Dean DM, Chai PR, Morgan JR. Miniaturization of an Anoikis assay using non-adhesive micromolded hydrogels. Cytotechnology. 2008 Feb; 56(2):81-90. PMID: 19002845.
    Citations: 2     Fields:    
  39. Napolitano AP, Chai P, Dean DM, Morgan JR. Dynamics of the self-assembly of complex cellular aggregates on micromolded nonadhesive hydrogels. Tissue Eng. 2007 Aug; 13(8):2087-94. PMID: 17518713.
    Citations: 54     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.