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Ryo Ohtomo, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Regenhardt RW, Das AS, Ohtomo R, Lo EH, Ayata C, Gurol ME. Pathophysiology of Lacunar Stroke: History's Mysteries and Modern Interpretations. J Stroke Cerebrovasc Dis. 2019 May 28. PMID: 31151839.
    Citations:    
  2. Li B, Ohtomo R, Thunemann M, Adams SR, Yang J, Fu B, Yaseen MA, Ran C, Polimeni JR, Boas DA, Devor A, Lo EH, Arai K, Sakadžic S. Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion. J Cereb Blood Flow Metab. 2019 Mar 04; 271678X19831016. PMID: 30829101.
    Citations:    
  3. Bannai T, Mano T, Chen X, Ohtomo G, Ohtomo R, Tsuchida T, Koshi-Mano K, Hashimoto T, Okazawa H, Iwatsubo T, Tsuji S, Toda T, Iwata A. Chronic cerebral hypoperfusion shifts the equilibrium of amyloid ß oligomers to aggregation-prone species with higher molecular weight. Sci Rep. 2019 Feb 26; 9(1):2827. PMID: 30808940.
    Citations:    
  4. Hamanaka G, Ohtomo R, Takase H, Lok J, Arai K. White-matter repair: Interaction between oligodendrocytes and the neurovascular unit. Brain Circ. 2018 Jul-Sep; 4(3):118-123. PMID: 30450418.
    Citations:    
  5. Yamaguchi N, Mano T, Ohtomo R, Ishiura H, Almansour MA, Mori H, Kanda J, Shirota Y, Taira K, Morikawa T, Ikemura M, Yanagi Y, Murayama S, Shimizu J, Sakurai Y, Tsuji S, Iwata A. An Autopsy Case of Familial Neuronal Intranuclear Inclusion Disease with Dementia and Neuropathy. Intern Med. 2018 Dec 01; 57(23):3459-3462. PMID: 30101925.
    Citations:    Fields:    
  6. Hamanaka G, Ohtomo R, Takase H, Lok J, Arai K. Role of oligodendrocyte-neurovascular unit in white matter repair. Neurosci Lett. 2018 09 25; 684:175-180. PMID: 30006018.
    Citations:    Fields:    
  7. Ohtomo R, Iwata A, Arai K. Molecular Mechanisms of Oligodendrocyte Regeneration in White Matter-Related Diseases. Int J Mol Sci. 2018 Jun 12; 19(6). PMID: 29895784.
    Citations:    Fields:    Translation:HumansAnimalsCells
  8. Takase H, Liang AC, Miyamoto N, Hamanaka G, Ohtomo R, Maki T, Pham LD, Lok J, Lo EH, Arai K. Protective effects of a radical scavenger edaravone on oligodendrocyte precursor cells against oxidative stress. Neurosci Lett. 2018 03 06; 668:120-125. PMID: 29337010.
    Citations: 1     Fields:    Translation:AnimalsCells
  9. Ohtomo R, Bannai T, Ohtomo G, Shindo A, Tomimoto H, Tsuji S, Iwata A. Cilostazol alleviates white matter degeneration caused by chronic cerebral hypoperfusion in mice: Implication of its mechanism from gene expression analysis. Neurosci Lett. 2018 Jan 01; 662:247-252. PMID: 29080698.
    Citations: 1     Fields:    Translation:AnimalsCells
  10. Mano T, Nagata K, Nonaka T, Tarutani A, Imamura T, Hashimoto T, Bannai T, Koshi-Mano K, Tsuchida T, Ohtomo R, Takahashi-Fujigasaki J, Yamashita S, Ohyagi Y, Yamasaki R, Tsuji S, Tamaoka A, Ikeuchi T, Saido TC, Iwatsubo T, Ushijima T, Murayama S, Hasegawa M, Iwata A. Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease. Proc Natl Acad Sci U S A. 2017 11 07; 114(45):E9645-E9654. PMID: 29042514.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  11. Ohtomo R, Suzuki Y, Maeda N, Kawakami S, Yamada M, Iwata A, Nakase H. Successful treatment of recurrent primary CNS vasculitis with etanercept. J Neurol Sci. 2017 10 15; 381:200-202. PMID: 28991681.
    Citations:    Fields:    
  12. Oichi T, Chikuda H, Ohya J, Ohtomo R, Morita K, Matsui H, Fushimi K, Tanaka S, Yasunaga H. Mortality and morbidity after spinal surgery in patients with Parkinson's disease: a retrospective matched-pair cohort study. Spine J. 2017 04; 17(4):531-537. PMID: 27884743.
    Citations: 1     Fields:    Translation:Humans
  13. Ohtomo R, Tsuji S, Iwata A. Persistent pain as a non-motor symptom in corticobasal syndrome. J Clin Neurosci. 2016 Jul; 29:35-7. PMID: 26898576.
    Citations:    Fields:    Translation:Humans
  14. Sawamura H, Yamamoto T, Ohtomo R, Bannai T, Wakakura M, Tsuji S. Anti-NMDA receptor encephalitis associated with transient cerebral dyschromatopsia, prosopagnosia, and lack of stereopsis. J Neuroophthalmol. 2014 Jun; 34(2):144-8. PMID: 24647141.
    Citations: 1     Fields:    Translation:Humans
  15. Ohtomo R, Matsukawa T, Tsuji S, Iwata A. Abadie's sign in adrenomyeloneuropathy. J Neurol Sci. 2014 May 15; 340(1-2):245-6. PMID: 24726718.
    Citations:    Fields:    Translation:Humans
  16. Ohtomo R, Shirota Y, Iwata A, Shimizu J, Tsuji S. Cerebral microbleeding in varicella-zoster viral meningitis: an early sign of vasculopathy? Neurology. 2014 Mar 04; 82(9):814-5. PMID: 24463624.
    Citations:    Fields:    Translation:HumansCells
  17. Ohtomo R, Iwata A, Tsuji S. Unilateral opercular infarction presenting with Foix-Chavany-Marie Syndrome. J Stroke Cerebrovasc Dis. 2014 Jan; 23(1):179-81. PMID: 23040957.
    Citations: 1     Fields:    Translation:Humans
  18. Shirota Y, Ohtomo R, Hanajima R, Terao Y, Tsutsumi R, Tsuji S. [Severely abnormal electroencephalogram in two patients who were treated with cefepime]. Rinsho Shinkeigaku. 2012; 52(5):356-9. PMID: 22688116.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.