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Parmit Singh, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ballandras-Colas A, Chivukula V, Gruszka DT, Shan Z, Singh PK, Pye VE, McLean RK, Bedwell GJ, Li W, Nans A, Cook NJ, Fadel HJ, Poeschla EM, Griffiths DJ, Vargas J, Taylor IA, Lyumkis D, Yardimci H, Engelman AN, Cherepanov P. Multivalent interactions essential for lentiviral integrase function. Nat Commun. 2022 May 03; 13(1):2416. PMID: 35504909.
    Citations:    Fields:    Translation:HumansAnimalsCells
  2. Singh PK, Bedwell GJ, Engelman AN. Spatial and Genomic Correlates of HIV-1 Integration Site Targeting. Cells. 2022 02 14; 11(4). PMID: 35203306.
    Citations:    Fields:    Translation:Cells
  3. Bedwell GJ, Jang S, Li W, Singh PK, Engelman AN. rigrag: high-resolution mapping of genic targeting preferences during HIV-1 integration in vitro and in vivo. Nucleic Acids Res. 2021 07 21; 49(13):7330-7346. PMID: 34165568.
    Citations: 3     Fields:    Translation:HumansCells
  4. Zheng Y, Schubert HL, Singh PK, Martins LJ, Engelman AN, D'Orso I, Hill CP, Planelles V. Cleavage and Polyadenylation Specificity Factor 6 Is Required for Efficient HIV-1 Latency Reversal. mBio. 2021 06 29; 12(3):e0109821. PMID: 34154414.
    Citations:    Fields:    Translation:HumansCells
  5. Francis AC, Marin M, Singh PK, Achuthan V, Prellberg MJ, Palermino-Rowland K, Lan S, Tedbury PR, Sarafianos SG, Engelman AN, Melikyan GB. Publisher Correction: HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains. Nat Commun. 2020 Nov 26; 11(1):6165. PMID: 33244008.
    Citations: 1     Fields:    
  6. Bester SM, Wei G, Zhao H, Adu-Ampratwum D, Iqbal N, Courouble VV, Francis AC, Annamalai AS, Singh PK, Shkriabai N, Van Blerkom P, Morrison J, Poeschla EM, Engelman AN, Melikyan GB, Griffin PR, Fuchs JR, Asturias FJ, Kvaratskhelia M. Structural and mechanistic bases for a potent HIV-1 capsid inhibitor. Science. 2020 10 16; 370(6514):360-364. PMID: 33060363.
    Citations: 28     Fields:    Translation:HumansCells
  7. Li W, Singh PK, Sowd GA, Bedwell GJ, Jang S, Achuthan V, Oleru AV, Wong D, Fadel HJ, Lee K, KewalRamani VN, Poeschla EM, Herschhorn A, Engelman AN. CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration. mBio. 2020 09 29; 11(5). PMID: 32994325.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  8. Francis AC, Marin M, Singh PK, Achuthan V, Prellberg MJ, Palermino-Rowland K, Lan S, Tedbury PR, Sarafianos SG, Engelman AN, Melikyan GB. HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains. Nat Commun. 2020 07 14; 11(1):3505. PMID: 32665593.
    Citations: 40     Fields:    Translation:HumansCells
  9. Anderson-Daniels J, Singh PK, Sowd GA, Li W, Engelman AN, Aiken C. Dominant Negative MA-CA Fusion Protein Is Incorporated into HIV-1 Cores and Inhibits Nuclear Entry of Viral Preintegration Complexes. J Virol. 2019 11 01; 93(21). PMID: 31413124.
    Citations: 9     Fields:    Translation:HumansCells
  10. Jang S, Cook NJ, Pye VE, Bedwell GJ, Dudek AM, Singh PK, Cherepanov P, Engelman AN. Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6. Nucleic Acids Res. 2019 05 21; 47(9):4663-4683. PMID: 30916345.
    Citations: 17     Fields:    Translation:HumansCells
  11. Engelman AN, Singh PK. Cellular and molecular mechanisms of HIV-1 integration targeting. Cell Mol Life Sci. 2018 Jul; 75(14):2491-2507. PMID: 29417178.
    Citations: 30     Fields:    Translation:HumansCells
  12. Singh PK, Plumb MR, Ferris AL, Iben JR, Wu X, Fadel HJ, Luke BT, Esnault C, Poeschla EM, Hughes SH, Kvaratskhelia M, Levin HL. LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes. Genes Dev. 2015 Nov 01; 29(21):2287-97. PMID: 26545813.
    Citations: 49     Fields:    Translation:HumansCells
  13. Guo Y, Singh PK, Levin HL. A long terminal repeat retrotransposon of Schizosaccharomyces japonicus integrates upstream of RNA pol III transcribed genes. Mob DNA. 2015; 6:19. PMID: 26457121.
    Citations: 8     
  14. Singh PK, Bourque G, Craig NL, Dubnau JT, Feschotte C, Flasch DA, Gunderson KL, Malik HS, Moran JV, Peters JE, Slotkin RK, Levin HL. Mobile genetic elements and genome evolution 2014. Mob DNA. 2014; 5:26. PMID: 30117500.
    Citations: 3     
  15. Matreyek KA, Wang W, Serrao E, Singh PK, Levin HL, Engelman A. Host and viral determinants for MxB restriction of HIV-1 infection. Retrovirology. 2014 Oct 25; 11:90. PMID: 25348155.
    Citations: 52     Fields:    Translation:HumansCells
  16. Kasbekar DP, Singh PK, Ramakrishnan M, Raj KB. Carrefour Mme. Gras: a wild-isolated Neurospora crassa strain that suppresses meiotic silencing by unpaired DNA and uncovers a novel ascospore stability defect. Fungal Genet Biol. 2011 Jun; 48(6):612-20. PMID: 21295150.
    Citations: 2     Fields:    Translation:AnimalsCells
  17. Singh PK, Iyer SV, Sowjanya TN, Raj BK, Kasbekar DP. Translocations used to generate chromosome segment duplications in Neurospora can disrupt genes and create novel open reading frames. J Biosci. 2010 Dec; 35(4):539-46. PMID: 21289436.
    Citations: 8     Fields:    Translation:AnimalsCells
  18. Singh PK, Iyer SV, Ramakrishnan M, Kasbekar DP. Chromosome segment duplications in Neurospora crassa: barren crosses beget fertile science. Bioessays. 2009 Feb; 31(2):209-19. PMID: 19204993.
    Citations: 5     Fields:    Translation:AnimalsCells
  19. Goyal A, Saxena P, Rahman A, Singh PK, Kasbekar DP, Gokhale RS, Sankaranarayanan R. Structural insights into biosynthesis of resorcinolic lipids by a type III polyketide synthase in Neurospora crassa. J Struct Biol. 2008 Jun; 162(3):411-21. PMID: 18462950.
    Citations: 17     Fields:    Translation:AnimalsCells
  20. Singh PK, Kasbekar DP. Titration of repeat-induced point mutation (RIP) by chromosome segment duplications in Neurospora crassa. Genetica. 2008 Nov; 134(3):267-75. PMID: 18046508.
    Citations: 3     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.