Harvard Catalyst Profiles

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Siang Boon Koh, Ph.D.


University of CambridgePhD

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Koh SB. The expanding role of WEE1. Cell Signal. 2022 Mar 16; 94:110310. PMID: 35304285.
    Citations:    Fields:    
  2. Koh SB, Ellisen LW. Immune activation and evolution through chemotherapy plus checkpoint blockade in triple-negative breast cancer. Cancer Cell. 2021 12 13; 39(12):1562-1564. PMID: 34767761.
    Citations: 2     Fields:    Translation:Humans
  3. Koh SB, Dontchos BN, Bossuyt V, Edmonds C, Cristea S, Melkonjan N, Mortensen L, Ma A, Beyerlin K, Denault E, Niehoff E, Hirz T, Sykes DB, Michor F, Specht M, Lehman C, Ellisen LW, Spring LM. Systematic tissue collection during clinical breast biopsy is feasible, safe and enables high-content translational analyses. NPJ Precis Oncol. 2021 Sep 21; 5(1):85. PMID: 34548623.
  4. KalantarMotamedi Y, Choi RJ, Koh SB, Bramhall JL, Fan TP, Bender A. Prediction and identification of synergistic compound combinations against pancreatic cancer cells. iScience. 2021 Sep 24; 24(9):103080. PMID: 34585118.
  5. Koh SB, Ross K, Isakoff SJ, Melkonjan N, He L, Matissek KJ, Schultz A, Mayer EL, Traina TA, Carey LA, Rugo HS, Liu MC, Stearns V, Langenbucher A, Saladi SV, Ramaswamy S, Lawrence MS, Ellisen LW. RASAL2 Confers Collateral MEK/EGFR Dependency in Chemoresistant Triple-Negative Breast Cancer. Clin Cancer Res. 2021 09 01; 27(17):4883-4897. PMID: 34168046.
    Citations: 2     Fields:    
  6. Qiao S*, Koh SB*, Vivekanandan V, Salunke D, Patra KC, Zaganjor E, Ross K, Mizukami Y, Jeanfavre S, Chen A, Mino-Kenudson M, Ramaswamy S, Clish C, Haigis M, Bardeesy N, Ellisen LW. *Co-first authors. REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors. Genes Dev. 2020; 34(11-12):751-766. PMID: 32273287.
  7. Koh SB. Signaling dynamics of DNA damage response invoked by combination therapy are dose-dependent. J Biol Chem. 2019 02 08; 294(6):2191. PMID: 30737318.
    Citations: 1     Fields:    Translation:Cells
  8. Wallez Y, Dunlop CR, Johnson TI, Koh SB, Fornari C, Yates JWT, Bernaldo de Quirós Fernández S, Lau A, Richards FM, Jodrell DI. The ATR Inhibitor AZD6738 Synergizes with Gemcitabine In Vitro and In Vivo to Induce Pancreatic Ductal Adenocarcinoma Regression. Mol Cancer Ther. 2018 08; 17(8):1670-1682. PMID: 29891488.
    Citations: 32     Fields:    Translation:HumansAnimals
  9. Koh SB, Wallez Y, Dunlop CR, Bernaldo de Quirós Fernández S, Bapiro TE, Richards FM, Jodrell DI. Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine. Cancer Res. 2018 06 01; 78(11):3054-3066. PMID: 29735549.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  10. Jackson RC, Di Veroli GY, Koh SB, Goldlust I, Richards FM, Jodrell DI. Modelling of the cancer cell cycle as a tool for rational drug development: A systems pharmacology approach to cyclotherapy. PLoS Comput Biol. 2017 05; 13(5):e1005529. PMID: 28467408.
    Citations: 3     Fields:    Translation:HumansCells
  11. Grah JS, Harrington JA, Koh SB, Pike JA, Schreiner A, Burger M, Schönlieb CB, Reichelt S. Mathematical imaging methods for mitosis analysis in live-cell phase contrast microscopy. Methods. 2017 02 15; 115:91-99. PMID: 28189773.
    Citations:    Fields:    Translation:HumansCells
  12. Koh SB, Mascalchi P, Rodriguez E, Lin Y, Jodrell DI, Richards FM, Lyons SK. A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level. J Cell Sci. 2017 01 15; 130(2):512-520. PMID: 27888217.
    Citations: 16     Fields:    Translation:HumansCells
  13. Di Veroli GY, Fornari C, Goldlust I, Mills G, Koh SB, Bramhall JL, Richards FM, Jodrell DI. An automated fitting procedure and software for dose-response curves with multiphasic features. Sci Rep. 2015 Oct 01; 5:14701. PMID: 26424192.
    Citations: 36     Fields:    Translation:Humans
  14. Koh SB, Courtin A, Boyce RJ, Boyle RG, Richards FM, Jodrell DI. CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus. Cancer Res. 2015 Sep 01; 75(17):3583-95. PMID: 26141863.
    Citations: 29     Fields:    Translation:HumansCells
  15. Tan KL, Koh SB, Ee RP, Khan M, Go ML. Curcumin analogues with potent and selective anti-proliferative activity on acute promyelocytic leukemia: involvement of accumulated misfolded nuclear receptor co-repressor (N-CoR) protein as a basis for selective activity. ChemMedChem. 2012 Sep; 7(9):1567-79. PMID: 22887959.
    Citations: 5     Fields:    Translation:HumansCells
  16. Yeo WK, Tan KL, Koh SB, Khan M, Nilar S, Go ML. Exploration and optimization of structure-activity relationships in drug design using the Taguchi method. ChemMedChem. 2012 Jun; 7(6):977-82. PMID: 22555964.
    Citations: 1     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.