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Yael Ben-Nun, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hauseman ZJ, Harvey EP, Newman CE, Wales TE, Bucci JC, Mintseris J, Schweppe DK, David L, Fan L, Cohen DT, Herce HD, Mourtada R, Ben-Nun Y, Bloch NB, Hansen SB, Wu H, Gygi SP, Engen JR, Walensky LD. Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization. Mol Cell. 2020 Jul 02; 79(1):68-83.e7. PMID: 32533918.
    Citations:    
  2. Ben-Nun Y, Seo HS, Harvey EP, Hauseman ZJ, Wales TE, Newman CE, Cathcart AM, Engen JR, Dhe-Paganon S, Walensky LD. Identification of a Structural Determinant for Selective Targeting of HDMX. Structure. 2020 Jul 07; 28(7):847-857.e5. PMID: 32359398.
    Citations:    
  3. Weiss-Sadan T, Ben-Nun Y, Maimoun D, Merquiol E, Abd-Elrahman I, Gotsman I, Blum G. A Theranostic Cathepsin Activity-Based Probe for Noninvasive Intervention in Cardiovascular Diseases. Theranostics. 2019; 9(20):5731-5738. PMID: 31534515.
    Citations:    
  4. Weiss-Sadan T, Itzhak G, Kaschani F, Yu Z, Mahameed M, Anaki A, Ben-Nun Y, Merquiol E, Tirosh B, Kessler B, Kaiser M, Blum G. Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation. Mol Cell Proteomics. 2019 07; 18(7):1330-1344. PMID: 31010818.
    Citations:    
  5. Weiss-Sadan T, Maimoun D, Oelschlagel D, Kaschani F, Misiak D, Gaikwad H, Ben-Nun Y, Merquiol E, Anaki A, Tsvirkun D, Kaiser M, Michl P, Gotsman I, Blum G. Cathepsins Drive Anti-Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam Cells. Cell Physiol Biochem. 2019; 53(3):550-572. PMID: 31529928.
    Citations:    
  6. Tsvirkun D, Ben-Nun Y, Merquiol E, Zlotver I, Meir K, Weiss-Sadan T, Matok I, Popovtzer R, Blum G. CT Imaging of Enzymatic Activity in Cancer Using Covalent Probes Reveal a Size-Dependent Pattern. J Am Chem Soc. 2018 09 26; 140(38):12010-12020. PMID: 30148621.
    Citations:    Fields:    
  7. Meena NK, Pattanayak SP, Ben-Nun Y, Benhamron S, Kumar S, Merquiol E, Hövelmeyer N, Blum G, Tirosh B. mTORC1 activation in B cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity. Immunology. 2018 12; 155(4):505-518. PMID: 30144045.
    Citations:    Fields:    
  8. Blau R, Epshtein Y, Pisarevsky E, Tiram G, Israeli Dangoor S, Yeini E, Krivitsky A, Eldar-Boock A, Ben-Shushan D, Gibori H, Scomparin A, Green O, Ben-Nun Y, Merquiol E, Doron H, Blum G, Erez N, Grossman R, Ram Z, Shabat D, Satchi-Fainaro R. Image-guided surgery using near-infrared Turn-ON fluorescent nanoprobes for precise detection of tumor margins. Theranostics. 2018; 8(13):3437-3460. PMID: 30026858.
    Citations:    Fields:    
  9. Gaikwad HK, Tsvirkun D, Ben-Nun Y, Merquiol E, Popovtzer R, Blum G. Molecular Imaging of Cancer Using X-ray Computed Tomography with Protease Targeted Iodinated Activity-Based Probes. Nano Lett. 2018 03 14; 18(3):1582-1591. PMID: 29470072.
    Citations: 1     Fields:    
  10. Ben-Nun Y, Fichman G, Adler-Abramovich L, Turk B, Gazit E, Blum G. Cathepsin nanofiber substrates as potential agents for targeted drug delivery. J Control Release. 2017 07 10; 257:60-67. PMID: 27908759.
    Citations: 1     Fields:    Translation:HumansCells
  11. Alishekevitz D, Gingis-Velitski S, Kaidar-Person O, Gutter-Kapon L, Scherer SD, Raviv Z, Merquiol E, Ben-Nun Y, Miller V, Rachman-Tzemah C, Timaner M, Mumblat Y, Ilan N, Loven D, Hershkovitz D, Satchi-Fainaro R, Blum G, Sleeman JP, Vlodavsky I, Shaked Y. Macrophage-Induced Lymphangiogenesis and Metastasis following Paclitaxel Chemotherapy Is Regulated by VEGFR3. Cell Rep. 2016 10 25; 17(5):1344-1356. PMID: 27783948.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  12. Abd-Elrahman I, Kosuge H, Wises Sadan T, Ben-Nun Y, Meir K, Rubinstein C, Bogyo M, McConnell MV, Blum G. Cathepsin Activity-Based Probes and Inhibitor for Preclinical Atherosclerosis Imaging and Macrophage Depletion. PLoS One. 2016; 11(8):e0160522. PMID: 27532109.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  13. Abd-Elrahman I, Meir K, Kosuge H, Ben-Nun Y, Weiss Sadan T, Rubinstein C, Samet Y, McConnell MV, Blum G. Characterizing Cathepsin Activity and Macrophage Subtypes in Excised Human Carotid Plaques. Stroke. 2016 Apr; 47(4):1101-8. PMID: 26941255.
    Citations: 3     Fields:    Translation:HumansCells
  14. Ben-Nun Y, Merquiol E, Brandis A, Turk B, Scherz A, Blum G. Photodynamic quenched cathepsin activity based probes for cancer detection and macrophage targeted therapy. Theranostics. 2015; 5(8):847-62. PMID: 26000057.
    Citations: 8     Fields:    Translation:AnimalsCells
  15. Salpeter SJ, Pozniak Y, Merquiol E, Ben-Nun Y, Geiger T, Blum G. A novel cysteine cathepsin inhibitor yields macrophage cell death and mammary tumor regression. Oncogene. 2015 Dec 10; 34(50):6066-78. PMID: 25798843.
    Citations: 8     Fields:    Translation:AnimalsCells
  16. Ben-Aderet L, Merquiol E, Fahham D, Kumar A, Reich E, Ben-Nun Y, Kandel L, Haze A, Liebergall M, Kosinska MK, Steinmeyer J, Turk B, Blum G, Dvir-Ginzberg M. Detecting cathepsin activity in human osteoarthritis via activity-based probes. Arthritis Res Ther. 2015 Mar 20; 17:69. PMID: 25889265.
    Citations: 5     Fields:    Translation:HumansCells
  17. Rothberg JM, Bailey KM, Wojtkowiak JW, Ben-Nun Y, Bogyo M, Weber E, Moin K, Blum G, Mattingly RR, Gillies RJ, Sloane BF. Acid-mediated tumor proteolysis: contribution of cysteine cathepsins. Neoplasia. 2013 Oct; 15(10):1125-37. PMID: 24204192.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.