Harvard Catalyst Profiles

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Nitesh Shashikanth, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Srivastava AK, Venkata BS, Sweat YY, Rizzo HR, Jean-François L, Zuo L, Kurgan KW, Moore P, Shashikanth N, Smok I, Sachleben JR, Turner JR, Meredith SC. Serine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin a-helical bundle. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2204618119. PMID: 35969745; PMCID: PMC9407527.
    Citations:    Fields:    Translation:AnimalsCells
  2. Shashikanth N, France MM, Xiao R, Haest X, Rizzo HE, Yeste J, Reiner J, Turner JR. Tight junction channel regulation by interclaudin interference. Nat Commun. 2022 06 30; 13(1):3780. PMID: 35773259; PMCID: PMC9246906.
    Citations:    Fields:    Translation:Cells
  3. Zuo L, Kuo WT, Cao F, Chanez-Paredes SD, Zeve D, Mannam P, Jean-François L, Day A, Vallen Graham W, Sweat YY, Shashikanth N, Breault DT, Turner JR. Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn's disease. Gut. 2022 May 10. PMID: 35537812.
    Citations:    Fields:    
  4. Shashikanth N, Rizzo HE, Pongkorpsakol P, Heneghan JF, Turner JR. Correction: Electrophysiologic Analysis of Tight Junction Size and Charge Selectivity. Curr Protoc. 2021 Sep; 1(9):e259. PMID: 34495581.
    Citations:    Fields:    
  5. Shashikanth N, Rizzo HE, Pongkorpsakol P, Heneghan JF, Turner JR. Electrophysiologic Analysis of Tight Junction Size and Charge Selectivity. Curr Protoc. 2021 Jun; 1(6):e143. PMID: 34106526; PMCID: PMC8541820.
    Citations: 2     Fields:    Translation:Cells
  6. Raju P, Shashikanth N, Tsai PY, Pongkorpsakol P, Chanez-Paredes S, Steinhagen PR, Kuo WT, Singh G, Tsukita S, Turner JR. Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice. J Clin Invest. 2020 10 01; 130(10):5197-5208. PMID: 32516134; PMCID: PMC7524482.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  7. Kuo WT, Shen L, Zuo L, Shashikanth N, Ong MLDM, Wu L, Zha J, Edelblum KL, Wang Y, Wang Y, Nilsen SP, Turner JR. Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression. Gastroenterology. 2019 11; 157(5):1323-1337. PMID: 31401143; PMCID: PMC6815722.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  8. Shashikanth N, Yeruva S, Ong MLDM, Odenwald MA, Pavlyuk R, Turner JR. Epithelial Organization: The Gut and Beyond. Compr Physiol. 2017 Sep 12; 7(4):1497-1518. PMID: 28915334.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  9. Shashikanth N, Kisting MA, Leckband DE. Corrigendum: Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions. Sci Rep. 2017 02 09; 7:41469. PMID: 28181573.
    Citations:    Fields:    
  10. Cai Y, Shashikanth N, Leckband DE, Schwartz DK. Cadherin Diffusion in Supported Lipid Bilayers Exhibits Calcium-Dependent Dynamic Heterogeneity. Biophys J. 2016 Dec 20; 111(12):2658-2665. PMID: 28002742; PMCID: PMC5192687.
    Citations: 6     Fields:    Translation:Cells
  11. Odenwald MA, Choi W, Buckley A, Shashikanth N, Joseph NE, Wang Y, Warren MH, Buschmann MM, Pavlyuk R, Hildebrand J, Margolis B, Fanning AS, Turner JR. ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture. J Cell Sci. 2017 01 01; 130(1):243-259. PMID: 27802160; PMCID: PMC5394778.
    Citations: 53     Fields:    Translation:HumansCells
  12. Shashikanth N, Kisting MA, Leckband DE. Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions. Sci Rep. 2016 Mar 24; 6:23623. PMID: 27009566.
    Citations: 8     Fields:    Translation:HumansCells
  13. Shashikanth N, Petrova YI, Park S, Chekan J, Maiden S, Spano M, Ha T, Gumbiner BM, Leckband DE. Allosteric Regulation of E-Cadherin Adhesion. J Biol Chem. 2015 Aug 28; 290(35):21749-61. PMID: 26175155.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  14. Barry AK, Tabdili H, Muhamed I, Wu J, Shashikanth N, Gomez GA, Yap AS, Gottardi CJ, de Rooij J, Wang N, Leckband DE. a-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction. J Cell Sci. 2014 Apr 15; 127(Pt 8):1779-91. PMID: 24522187.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  15. Langer MD, Guo H, Shashikanth N, Pierce JM, Leckband DE. N-glycosylation alters cadherin-mediated intercellular binding kinetics. J Cell Sci. 2012 May 15; 125(Pt 10):2478-85. PMID: 22344255.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.