Harvard Catalyst Profiles

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Matthew Kutys, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K99CA226366 (KUTYS, MATTHEW L) Sep 1, 2018 - Aug 31, 2019
    Non-canonical Notch1 regulation of proliferation and adherens junctions in breast cancer
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Polacheck WJ, Kutys ML, Tefft JB, Chen CS. Microfabricated blood vessels for modeling the vascular transport barrier. Nat Protoc. 2019 05; 14(5):1425-1454. PMID: 30953042.
  2. Wang WY, Pearson AT, Kutys ML, Choi CK, Wozniak MA, Baker BM, Chen CS. Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration. APL Bioeng. 2018 Dec; 2(4):046107. PMID: 31069329.
  3. Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS. Force Generation via ß-Cardiac Myosin, Titin, and a-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. Dev Cell. 2018 01 08; 44(1):87-96.e5. PMID: 29316444.
    Citations: 2     Fields:    Translation:HumansCells
  4. Polacheck WJ, Kutys ML, Yang J, Eyckmans J, Wu Y, Vasavada H, Hirschi KK, Chen CS. A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Nature. 2017 12 14; 552(7684):258-262. PMID: 29160307.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  5. Kutys ML, Chen CS. Forces and mechanotransduction in 3D vascular biology. Curr Opin Cell Biol. 2016 10; 42:73-79. PMID: 27209346.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  6. Kutys ML, Yamada KM. Rho GEFs and GAPs: emerging integrators of extracellular matrix signaling. Small GTPases. 2015; 6(1):16-9. PMID: 25862162.
    Citations: 2     Fields:    Translation:HumansCells
  7. Kutys ML, Yamada KM. An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration. Nat Cell Biol. 2014 Sep; 16(9):909-17. PMID: 25150978.
    Citations: 23     Fields:    Translation:HumansCells
  8. Doyle AD, Petrie RJ, Kutys ML, Yamada KM. Dimensions in cell migration. Curr Opin Cell Biol. 2013 Oct; 25(5):642-9. PMID: 23850350.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  9. Kutys ML, Doyle AD, Yamada KM. Regulation of cell adhesion and migration by cell-derived matrices. Exp Cell Res. 2013 Oct 01; 319(16):2434-9. PMID: 23751565.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  10. Li X, Zhou Q, Sunkara M, Kutys ML, Wu Z, Rychahou P, Morris AJ, Zhu H, Evers BM, Huang C. Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I ? by HECTD1 regulates focal adhesion dynamics and cell migration. J Cell Sci. 2013 Jun 15; 126(Pt 12):2617-28. PMID: 23572508.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  11. Doyle AD, Kutys ML, Conti MA, Matsumoto K, Adelstein RS, Yamada KM. Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics. J Cell Sci. 2012 May 01; 125(Pt 9):2244-56. PMID: 22328520.
    Citations: 37     Fields:    Translation:AnimalsCells
  12. Kutys ML, Fricks J, Hancock WO. Monte Carlo analysis of neck linker extension in kinesin molecular motors. PLoS Comput Biol. 2010 Nov 04; 6(11):e1000980. PMID: 21079666.
    Citations: 10     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.