Harvard Catalyst Profiles

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David Abasiwani Alagpulinsa, Ph.D.

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University of Arkansas for Medical Sciences, Little Rock, AR, USAPhD2015Interdisciplinary Biomedical Sciences
2022 - 2024
JDRF Diversifying Diabetes Research Talent in Academia Grant Award
MGH SAC Poster of Distinction Award
2020 - 2023
MGH Physician-Scientist Development Award
2019 - 2020
Tosteson & Fund for Medical Discovery Postdoctoral Fellowship Award
MGH Institutional Nominee for American Diabetes Association Pathway to Stop Diabetes Award
MGH SAC Poster of Distinction Award
MGH Postdoc Poster of Merit Award
ASH Abstract Achievement Award
Keystone Symposia Scholarship


Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Alagpulinsa DA, Toribio MP, Alhallak I, Shmookler Reis RJ. Advances in understanding the molecular basis of clonal hematopoiesis. Trends Mol Med. 2022 05; 28(5):360-377. PMID: 35341686.
    Citations: 1     Fields:    Translation:HumansCells
  2. Alagpulinsa DA, Jei L, Pop R, Veres A, Deng H, Zhang J, Kawai K, Collins SS, Sobell D, Chapin MH, Verill D, Melton DA, Markmann JF, Poznansky MC. 209.6: Long-term Functional Survival of Human Stem Cell-derived Islets Microencapsulated in Alginate With CXCL12 in Non-human Primates Without Immunosuppression. Transplantation. 2021 Dec 01; 105(12 Suppl 2):S16. PMID: 34908317.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Alolga RN, Opoku-Damoah Y, Alagpulinsa DA, Huang FQ, Ma G, Chavez Leon MASC, Kudzai C, Yin X, Ding Y. Metabolomic and transcriptomic analyses of the anti-rheumatoid arthritis potential of xylopic acid in a bioinspired lipoprotein nanoformulation. Biomaterials. 2021 01; 268:120482. PMID: 33307367.
    Citations: 2     Fields:    Translation:AnimalsCells
  4. Alagpulinsa DA, Szalat RE, Poznansky MC, Shmookler Reis RJ. Genomic Instability in Multiple Myeloma. Trends Cancer. 2020 10; 6(10):858-873. PMID: 32487486.
    Citations: 8     Fields:    Translation:HumansAnimals
  5. Alagpulinsa DA, Kumar S, Talluri S, Nanjappa P, Buon L, Chakraborty C, Samur MK, Szalat R, Shammas MA, Munshi NC. Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma. Blood Adv. 2019 12 10; 3(23):3968-3972. PMID: 31805191.
    Citations: 6     Fields:    Translation:Humans
  6. Alagpulinsa DA, Cao JJL, Driscoll RK, Sîrbulescu RF, Penson MFE, Sremac M, Engquist EN, Brauns TA, Markmann JF, Melton DA, Poznansky MC. Alginate-microencapsulation of human stem cell-derived ß cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression. Am J Transplant. 2019 07; 19(7):1930-1940. PMID: 30748094.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  7. Alagpulinsa DA, Cao JJL, Sobell D, Poznansky MC. Harnessing CXCL12 signaling to protect and preserve functional ß-cell mass and for cell replacement in type 1 diabetes. Pharmacol Ther. 2019 01; 193:63-74. PMID: 30149101.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  8. Alagpulinsa DA, Ayyadevara S, Yaccoby S, Shmookler Reis RJ. A Cyclin-Dependent Kinase Inhibitor, Dinaciclib, Impairs Homologous Recombination and Sensitizes Multiple Myeloma Cells to PARP Inhibition. Mol Cancer Ther. 2016 Feb; 15(2):241-50. PMID: 26719576; PMCID: PMC4747838.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  9. Alagpulinsa DA, Yaccoby S, Ayyadevara S, Shmookler Reis RJ. A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment. Cancer Biol Ther. 2015; 16(6):976-86. PMID: 25996477; PMCID: PMC4622566.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  10. Alagpulinsa DA, Ayyadevara S, Shmookler Reis RJ. A Small-Molecule Inhibitor of RAD51 Reduces Homologous Recombination and Sensitizes Multiple Myeloma Cells to Doxorubicin. Front Oncol. 2014; 4:289. PMID: 25401086; PMCID: PMC4214226.
    Citations: 38     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.