Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Peng Yin, Ph.D.


DNA Nanotechnology for Programmable Drug Targeting and Localization to Cancer Cells
Summer, 06/01/11 - 08/17/11

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. RF1MH128861 (YIN, PENG) Sep 17, 2021 - Sep 16, 2024
    Platform technologies for scalable highly multiplexed proteomic phenotyping of the brain
    Role: Principal Investigator
  2. RF1MH124606 (BOYDEN, EDWARD S.) Sep 16, 2020 - Sep 15, 2023
    Multiplexed Nanoscale Protein Mapping Through Expansion Microscopy and Immuno-SABER
    Role: Co-Principal Investigator
  3. RF1MH124611 (CAI, DAWEN) Sep 14, 2020 - Sep 13, 2023
    Development of a scalable strategy for reconstructing cell-type determined connectome of the mammalian brain
    Role: Co-Principal Investigator
  4. RF1MH123401 (HUANG, FANG) Aug 20, 2020 - Aug 19, 2023
    Ultra-high resolution, multiplexed single molecule nanoscopy and functional characterization of neural circuits
    Role: Co-Principal Investigator
  5. R21CA235421 (YIN, PENG) Feb 1, 2019 - Jan 31, 2021
    Elucidating chromatin organization with molecular rulers
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Grun C, Werfel J, Zhang DY, Yin P. DyNAMiC Workbench: an integrated development environment for dynamic DNA nanotechnology. J R Soc Interface. 2015 Oct 06; 12(111):20150580. PMID: 26423437.
    Citations: 3     Fields:    Translation:Cells
  2. Knudsen JB, Liu L, Bank Kodal AL, Madsen M, Li Q, Song J, Woehrstein JB, Wickham SF, Strauss MT, Schueder F, Vinther J, Krissanaprasit A, Gudnason D, Smith AA, Ogaki R, Zelikin AN, Besenbacher F, Birkedal V, Yin P, Shih WM, Jungmann R, Dong M, Gothelf KV. Routing of individual polymers in designed patterns. Nat Nanotechnol. 2015 Oct; 10(10):892-8. PMID: 26322946.
    Citations: 47     Fields:    Translation:Cells
  3. Scheible MB, Ong LL, Woehrstein JB, Jungmann R, Yin P, Simmel FC. A Compact DNA Cube with Side Length 10 nm. Small. 2015 Oct 21; 11(39):5200-5. PMID: 26294348.
    Citations: 2     Fields:    
  4. Beliveau BJ, Boettiger AN, Avendaño MS, Jungmann R, McCole RB, Joyce EF, Kim-Kiselak C, Bantignies F, Fonseka CY, Erceg J, Hannan MA, Hoang HG, Colognori D, Lee JT, Shih WM, Yin P, Zhuang X, Wu CT. Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes. Nat Commun. 2015 May 12; 6:7147. PMID: 25962338; PMCID: PMC4430122.
    Citations: 148     Fields:    Translation:AnimalsCells
  5. Wei B, Vhudzijena MK, Robaszewski J, Yin P. Self-assembly of complex two-dimensional shapes from single-stranded DNA tiles. J Vis Exp. 2015 May 08; (99):e52486. PMID: 25993048.
    Citations: 1     Fields:    Translation:Cells
  6. Yin P. 75 DNA nanotech and super-resolution imaging. J Biomol Struct Dyn. 2015; 33 Suppl 1:49. PMID: 26103287.
  7. Green AA, Silver PA, Collins JJ, Yin P. Toehold switches: de-novo-designed regulators of gene expression. Cell. 2014 Nov 06; 159(4):925-39. PMID: 25417166.
    Citations: 211     Fields:    Translation:Cells
  8. Pardee K, Green AA, Ferrante T, Cameron DE, DaleyKeyser A, Yin P, Collins JJ. Paper-based synthetic gene networks. Cell. 2014 Nov 06; 159(4):940-54. PMID: 25417167; PMCID: PMC4243060.
    Citations: 199     Fields:    Translation:Cells
  9. Ke Y, Ong LL, Sun W, Song J, Dong M, Shih WM, Yin P. DNA brick crystals with prescribed depths. Nat Chem. 2014 Nov; 6(11):994-1002. PMID: 25343605.
    Citations: 34     Fields:    Translation:Cells
  10. Sun W, Boulais E, Hakobyan Y, Wang WL, Guan A, Bathe M, Yin P. Casting inorganic structures with DNA molds. Science. 2014 Nov 07; 346(6210):1258361. PMID: 25301973.
    Citations: 57     Fields:    Translation:Cells
  11. Wei B, Ong LL, Chen J, Jaffe AS, Yin P. Complex reconfiguration of DNA nanostructures. Angew Chem Int Ed Engl. 2014 Jul 14; 53(29):7475-9. PMID: 24899518.
    Citations: 7     Fields:    Translation:Cells
  12. Jin Z, Sun W, Yin P, Strano MS. Nanolithography based on metalized DNA templates for graphene patterning. Curr Protoc Chem Biol. 2014 Jun 03; 6(2):53-64. PMID: 24903883.
    Citations:    Fields:    Translation:Cells
  13. Sadowski JP, Calvert CR, Zhang DY, Pierce NA, Yin P. Developmental self-assembly of a DNA tetrahedron. ACS Nano. 2014 Apr 22; 8(4):3251-9. PMID: 24720462.
    Citations: 20     Fields:    Translation:Cells
  14. Iinuma R, Ke Y, Jungmann R, Schlichthaerle T, Woehrstein JB, Yin P. Polyhedra self-assembled from DNA tripods and characterized with 3D DNA-PAINT. Science. 2014 Apr 04; 344(6179):65-9. PMID: 24625926.
    Citations: 71     Fields:    Translation:Cells
  15. Wu Y, Zhang DY, Yin P, Vollmer F. Ultraspecific and highly sensitive nucleic acid detection by integrating a DNA catalytic network with a label-free microcavity. Small. 2014 May 28; 10(10):2067-76. PMID: 24585636.
    Citations: 10     Fields:    Translation:Cells
  16. Jungmann R, Avendaño MS, Woehrstein JB, Dai M, Shih WM, Yin P. Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT. Nat Methods. 2014 Mar; 11(3):313-8. PMID: 24487583.
    Citations: 328     Fields:    
  17. Jia J, Zhou A, Wei C, Jia X, Wang F, Li F, Wu X, Mok V, Gauthier S, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese. Alzheimers Dement. 2014 Jul; 10(4):439-447. PMID: 24418053.
    Citations: 53     Fields:    Translation:Humans
  18. Wei B, Dai M, Myhrvold C, Ke Y, Jungmann R, Yin P. Design space for complex DNA structures. J Am Chem Soc. 2013 Dec 04; 135(48):18080-8. PMID: 24256506.
    Citations: 12     Fields:    Translation:Cells
  19. Hochrein LM, Schwarzkopf M, Shahgholi M, Yin P, Pierce NA. Conditional Dicer substrate formation via shape and sequence transduction with small conditional RNAs. J Am Chem Soc. 2013 Nov 20; 135(46):17322-30. PMID: 24219616.
    Citations: 14     Fields:    
  20. Myhrvold C, Dai M, Silver PA, Yin P. Isothermal self-assembly of complex DNA structures under diverse and biocompatible conditions. Nano Lett. 2013 Sep 11; 13(9):4242-8. PMID: 23978049.
    Citations: 18     Fields:    Translation:Cells
  21. Schaus TE, Yin P. Molecular computing: in situ computation of cell identity. Nat Nanotechnol. 2013 Aug; 8(8):546-8. PMID: 23912106.
    Citations:    Fields:    Translation:HumansCells
  22. Jia J, Wang F, Wei C, Zhou A, Jia X, Li F, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of dementia in urban and rural areas of China. Alzheimers Dement. 2014 Jan; 10(1):1-9. PMID: 23871765.
    Citations: 147     Fields:    Translation:Humans
  23. Surwade SP, Zhou F, Wei B, Sun W, Powell A, O'Donnell C, Yin P, Liu H. Nanoscale growth and patterning of inorganic oxides using DNA nanostructure templates. J Am Chem Soc. 2013 May 08; 135(18):6778-81. PMID: 23574340.
    Citations: 17     Fields:    
  24. Zhao C, Yin P, Mei C, Li N, Yao W, Li X, Qi J, Fan K, Li Z, Wang L, Shi Y, Qiu S, Fan J, Zha X. Down-regulation of DNA methyltransferase 3B in staurosporine-induced apoptosis and its mechanism in human hepatocarcinoma cell lines. Mol Cell Biochem. 2013 Apr; 376(1-2):111-9. PMID: 23397112.
    Citations: 6     Fields:    Translation:HumansCells
  25. Jin Z, Sun W, Ke Y, Shih CJ, Paulus GL, Hua Wang Q, Mu B, Yin P, Strano MS. Metallized DNA nanolithography for encoding and transferring spatial information for graphene patterning. Nat Commun. 2013; 4:1663. PMID: 23575667.
    Citations: 25     Fields:    Translation:Cells
  26. Qi H, Ghodousi M, Du Y, Grun C, Bae H, Yin P, Khademhosseini A. DNA-directed self-assembly of shape-controlled hydrogels. Nat Commun. 2013; 4:2275. PMID: 24013352.
    Citations: 56     Fields:    Translation:Cells
  27. Ke Y, Ong LL, Shih WM, Yin P. Three-dimensional structures self-assembled from DNA bricks. Science. 2012 Nov 30; 338(6111):1177-83. PMID: 23197527.
    Citations: 230     Fields:    Translation:Cells
  28. Lin C, Jungmann R, Leifer AM, Li C, Levner D, Church GM, Shih WM, Yin P. Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA. Nat Chem. 2012 Oct; 4(10):832-9. PMID: 23000997.
    Citations: 60     Fields:    
  29. Shi Y, Yu PW, Lei X, Qian F, Zhao YL, Tang B, Hao YX, Yin P, Li J. [Influence of CO2 pneumoperitoneum pressures on the expression of adhesion molecules of gastric cancer cells]. Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Aug; 15(8):830-3. PMID: 22941688.
    Citations: 1     Fields:    Translation:HumansCells
  30. Wei B, Dai M, Yin P. Complex shapes self-assembled from single-stranded DNA tiles. Nature. 2012 May 30; 485(7400):623-6. PMID: 22660323.
    Citations: 187     Fields:    Translation:Cells
  31. Zhang DY, Chen SX, Yin P. Optimizing the specificity of nucleic acid hybridization. Nat Chem. 2012 Jan 22; 4(3):208-14. PMID: 22354435.
    Citations: 102     Fields:    Translation:HumansCells
  32. Uen YH, Ko PH, Yin PH, Liu TY, Chi CW, Lui WY. Glucocorticoid protects hepatoma cells against metabolic stress-induced cell death. Int J Oncol. 2008 Dec; 33(6):1263-70. PMID: 19020760.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  33. Lee HJ, Su Y, Lui WY, Chau GY, Yin PH, Lee HC, Chi CW. Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1alpha) upregulated E-cadherin expression in HepG2 cells. FEBS Lett. 2008 Mar 05; 582(5):627-34. PMID: 18242180.
    Citations: 7     Fields:    Translation:HumansCells
  34. Yin P, Choi HM, Calvert CR, Pierce NA. Programming biomolecular self-assembly pathways. Nature. 2008 Jan 17; 451(7176):318-22. PMID: 18202654.
    Citations: 270     Fields:    Translation:Cells
  35. Park SH, Yin P, Liu Y, Reif JH, LaBean TH, Yan H. Programmable DNA self-assemblies for nanoscale organization of ligands and proteins. Nano Lett. 2005 Apr; 5(4):729-33. PMID: 15826117.
    Citations: 43     Fields:    
  36. Yin P, Yan H, Daniell XG, Turberfield AJ, Reif JH. A unidirectional DNA walker that moves autonomously along a track. Angew Chem Int Ed Engl. 2004 Sep 20; 43(37):4906-11. PMID: 15372637.
    Citations: 69     Fields:    Translation:Cells
  37. Sui G, Affar el B, Shi Y, Brignone C, Wall NR, Yin P, Donohoe M, Luke MP, Calvo D, Grossman SR, Shi Y. Yin Yang 1 is a negative regulator of p53. Cell. 2004 Jun 25; 117(7):859-72. PMID: 15210108.
    Citations: 199     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.