Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

King-Hwa Ling, Ph.D.

Title
Institution
Department
Address
Phone

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang M, Ling KH, Tan JJ, Lu CB. Development and Differentiation of Midbrain Dopaminergic Neuron: From Bench to Bedside. Cells. 2020 Jun 18; 9(6). PMID: 32570916.
    Citations:    
  2. Lye MS, Tey YY, Tor YS, Shahabudin AF, Ibrahim N, Ling KH, Stanslas J, Loh SP, Rosli R, Lokman KA, Badamasi IM, Faris-Aldoghachi A, Abdul Razak NA. Predictors of recurrence of major depressive disorder. PLoS One. 2020; 15(3):e0230363. PMID: 32191745.
    Citations:    
  3. Mansor NI, Ntimi CM, Abdul-Aziz NM, Ling KH, Adam A, Rosli R, Hassan Z, Nordin N. Asymptomatic neurotoxicity of amyloid ß-peptides (Aß1-42 and Aß25-35) on mouse embryonic stem cell-derived neural cells. Bosn J Basic Med Sci. 2020 Mar 06. PMID: 32156249.
    Citations:    
  4. Jafarian S, Ling KH, Hassan Z, Perimal-Lewis L, Sulaiman MR, Perimal EK. Effect of zerumbone on scopolamine-induced memory impairment and anxiety-like behaviours in rats. Alzheimers Dement (N Y). 2019; 5:637-643. PMID: 31687471.
    Citations:    
  5. Fish-Low CY, Balami AD, Than LTL, Ling KH, Mohd Taib N, Md Shah A, Sekawi Z. Hypocalcemia, hypochloremia, and eosinopenia as clinical predictors of leptospirosis: A retrospective study. J Infect Public Health. 2020 Feb; 13(2):216-220. PMID: 31455598.
    Citations:    
  6. Hassan Z, Suhaimi FW, Ramanathan S, Ling KH, Effendy MA, Müller CP, Dringenberg HC. Mitragynine (Kratom) impairs spatial learning and hippocampal synaptic transmission in rats. J Psychopharmacol. 2019 07; 33(7):908-918. PMID: 31081443.
    Citations:    
  7. Fish-Low CY, Than LTL, Ling KH, Lin Q, Sekawi Z. Plasma proteome profiling reveals differentially expressed lipopolysaccharide-binding protein among leptospirosis patients. J Microbiol Immunol Infect. 2020 Feb; 53(1):157-162. PMID: 31029530.
    Citations:    
  8. Aliyu IA, Ling KH, Md Hashim NF, Lam JY, Chee HY. Annexin II as a Dengue Virus Serotype 2 Interacting Protein Mediating Virus Interaction on Vero Cells. Viruses. 2019 04 09; 11(4). PMID: 30970587.
    Citations:    
  9. Lee HC, Md Yusof HH, Leong MP, Zainal Abidin S, Seth EA, Hewitt CA, Vidyadaran S, Nordin N, Scott HS, Cheah PS, Ling KH. Gene and protein expression profiles of JAK-STAT signalling pathway in the developing brain of the Ts1Cje down syndrome mouse model. Int J Neurosci. 2019 Sep; 129(9):871-881. PMID: 30775947.
    Citations:    
  10. Yusof HH, Lee HC, Seth EA, Wu X, Hewitt CA, Scott HS, Cheah PS, Li YM, Chau DM, Ling KH. Expression Profiling of Notch Signalling Pathway and Gamma-Secretase Activity in the Brain of Ts1Cje Mouse Model of Down Syndrome. J Mol Neurosci. 2019 Apr; 67(4):632-642. PMID: 30758748.
    Citations:    
  11. Zainal Abidin S, Fam SZ, Chong CE, Abdullah S, Cheah PS, Nordin N, Ling KH. miR-3099 promotes neurogenesis and inhibits astrogliogenesis during murine neural development. Gene. 2019 May 20; 697:201-212. PMID: 30769142.
    Citations:    
  12. Aliyu IA, Ling KH, Md Hashim N, Chee HY. Annexin A2 extracellular translocation and virus interaction: A potential target for antivirus-drug discovery. Rev Med Virol. 2019 05; 29(3):e2038. PMID: 30746844.
    Citations:    
  13. Meyer K, Feldman HM, Lu T, Drake D, Lim ET, Ling KH, Bishop NA, Pan Y, Seo J, Lin YT, Su SC, Church GM, Tsai LH, Yankner BA. REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. Cell Rep. 2019 01 29; 26(5):1112-1127.e9. PMID: 30699343.
    Citations:    Fields:    
  14. Aldoghachi AF, Tor YS, Redzun SZ, Lokman KAB, Razaq NAA, Shahbudin AF, Badamasi IM, Cheah PS, Stanslas J, Veerakumarasivam A, Rosli R, Ibrahim N, Lye MS, Ling KH. Screening of brain-derived neurotrophic factor (BDNF) single nucleotide polymorphisms and plasma BDNF levels among Malaysian major depressive disorder patients. PLoS One. 2019; 14(1):e0211241. PMID: 30677092.
    Citations:    Fields:    
  15. Mansor NI, Nordin N, Mohamed F, Ling KH, Rosli R, Hassan Z. Crossing the Blood-Brain Barrier: A Review on Drug Delivery Strategies for Treatment of the Central Nervous System Diseases. Curr Drug Deliv. 2019; 16(8):698-711. PMID: 31456519.
    Citations:    
  16. Jabbarzadeh Kaboli P, Leong MP, Ismail P, Ling KH. Antitumor effects of berberine against EGFR, ERK1/2, P38 and AKT in MDA-MB231 and MCF-7 breast cancer cells using molecular modelling and in vitro study. Pharmacol Rep. 2019 Feb; 71(1):13-23. PMID: 30343043.
    Citations:    Fields:    
  17. Bala U, Leong MP, Lim CL, Shahar HK, Othman F, Lai MI, Law ZK, Ramli K, Htwe O, Ling KH, Cheah PS. Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model. PLoS One. 2018; 13(5):e0197711. PMID: 29795634.
    Citations:    Fields:    Translation:AnimalsCells
  18. Jabbarzadeh Kaboli P, Ismail P, Ling KH. Molecular modeling, dynamics simulations, and binding efficiency of berberine derivatives: A new group of RAF inhibitors for cancer treatment. PLoS One. 2018; 13(3):e0193941. PMID: 29565994.
    Citations:    Fields:    Translation:HumansCells
  19. Lim CL, Ling KH, Cheah PS. Isolation, cultivation and immunostaining of single myofibers: An improved approach to study the behavior of satellite cells. J Biol Methods. 2018; 5(1):e87. PMID: 31453240.
    Citations:    
  20. Kaboli PJ, Bazrafkan M, Ismail P, Ling KH. Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs. Recent Pat Anticancer Drug Discov. 2017 Nov 20; 12(4):384-400. PMID: 28969581.
    Citations: 1     Fields:    Translation:HumansCells
  21. Abidin SZ, Leong JW, Mahmoudi M, Nordin N, Abdullah S, Cheah PS, Ling KH. In Silico Prediction and Validation of Gfap as an miR-3099 Target in Mouse Brain. Neurosci Bull. 2017 Aug; 33(4):373-382. PMID: 28597341.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  22. Reza Etemadi M, Ling KH, Zainal Abidin S, Chee HY, Sekawi Z. Gene expression patterns induced at different stages of rhinovirus infection in human alveolar epithelial cells. PLoS One. 2017; 12(5):e0176947. PMID: 28558071.
    Citations: 2     Fields:    Translation:HumansCells
  23. Mohd-Zin SW, Abdullah NL, Abdullah A, Greene ND, Cheah PS, Ling KH, Yusof H, Marwan AI, Williams SM, York KT, Ahmad-Annuar A, Abdul-Aziz NM. Identification of the genomic mutation in Epha4(rb-2J/rb-2J) mice. Genome. 2016 Jul; 59(7):439-48. PMID: 27373307.
    Citations: 1     Fields:    Translation:AnimalsCells
  24. Leong JW, Abdullah S, Ling KH, Cheah PS. Spatiotemporal Expression and Molecular Characterization of miR-344b and miR-344c in the Developing Mouse Brain. Neural Plast. 2016; 2016:1951250. PMID: 27034842.
    Citations:    Fields:    Translation:AnimalsCells
  25. Ling KH, Brautigan PJ, Moore S, Fraser R, Leong MP, Leong JW, Zainal Abidin S, Lee HC, Cheah PS, Raison JM, Babic M, Lee YK, Daish T, Mattiske DM, Mann JR, Adelson DL, Thomas PQ, Hahn CN, Scott HS. In depth analysis of the Sox4 gene locus that consists of sense and natural antisense transcripts. Data Brief. 2016 Jun; 7:282-90. PMID: 26958646.
    Citations:    
  26. Ling KH, Brautigan PJ, Moore S, Fraser R, Cheah PS, Raison JM, Babic M, Lee YK, Daish T, Mattiske DM, Mann JR, Adelson DL, Thomas PQ, Hahn CN, Scott HS. Derivation of an endogenous small RNA from double-stranded Sox4 sense and natural antisense transcripts in the mouse brain. Genomics. 2016 Mar; 107(2-3):88-99. PMID: 26802803.
    Citations: 7     Fields:    Translation:AnimalsCells
  27. Lee HC, Tan KL, Cheah PS, Ling KH. Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain. Neural Plast. 2016; 2016:7434191. PMID: 26881131.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  28. Kaboli PJ, Rahmat A, Ismail P, Ling KH. MicroRNA-based therapy and breast cancer: A comprehensive review of novel therapeutic strategies from diagnosis to treatment. Pharmacol Res. 2015 Jul; 97:104-21. PMID: 25958353.
    Citations: 32     Fields:    Translation:Humans
  29. Zainal Abidin S, Tan EL, Chan SC, Jaafar A, Lee AX, Abd Hamid MH, Abdul Murad NA, Pakarul Razy NF, Azmin S, Ahmad Annuar A, Lim SY, Cheah PS, Ling KH, Mohamed Ibrahim N. DRD and GRIN2B polymorphisms and their association with the development of impulse control behaviour among Malaysian Parkinson's disease patients. BMC Neurol. 2015 Apr 22; 15:59. PMID: 25896831.
    Citations: 8     Fields:    Translation:Humans
  30. Zainal Abidin S, Abbaspourbabaei M, Ntimi CM, Siew WH, Pike-See C, Rosli R, Nordin N, Ling KH. MiR-3099 is Overexpressed in Differentiating 46c Mouse Embryonic Stem Cells upon Neural Induction. Malays J Med Sci. 2014 Dec; 21(Spec Issue):27-33. PMID: 25941460.
    Citations: 1     
  31. Bala U, Tan KL, Ling KH, Cheah PS. Harvesting the maximum length of sciatic nerve from adult mice: a step-by-step approach. BMC Res Notes. 2014 Oct 10; 7:714. PMID: 25304607.
    Citations: 1     Fields:    Translation:Animals
  32. Tan KL, Ling KH, Hewitt CA, Cheah PS, Simpson K, Gordon L, Pritchard MA, Smyth GK, Thomas T, Scott HS. Transcriptional profiling of the postnatal brain of the Ts1Cje mouse model of Down syndrome. Genom Data. 2014 Dec; 2:314-7. PMID: 26484118.
    Citations:    
  33. Ling KH, Hewitt CA, Tan KL, Cheah PS, Vidyadaran S, Lai MI, Lee HC, Simpson K, Hyde L, Pritchard MA, Smyth GK, Thomas T, Scott HS. Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks. BMC Genomics. 2014 Jul 22; 15:624. PMID: 25052193.
    Citations: 13     Fields:    Translation:AnimalsCells
  34. Jabbarzadeh Kaboli P, Rahmat A, Ismail P, Ling KH. Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. Eur J Pharmacol. 2014 Oct 05; 740:584-95. PMID: 24973693.
    Citations: 19     Fields:    Translation:HumansAnimals
  35. Atshan SS, Shamsudin MN, Karunanidhi A, van Belkum A, Lung LT, Sekawi Z, Nathan JJ, Ling KH, Seng JS, Ali AM, Abduljaleel SA, Hamat RA. Quantitative PCR analysis of genes expressed during biofilm development of methicillin resistant Staphylococcus aureus (MRSA). Infect Genet Evol. 2013 Aug; 18:106-12. PMID: 23669446.
    Citations: 8     Fields:    Translation:HumansCells
  36. Siew WH, Tan KL, Babaei MA, Cheah PS, Ling KH. MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID, and Fragile X syndrome. Front Cell Neurosci. 2013; 7:41. PMID: 23596395.
    Citations: 11     
  37. Gagliardi L, Ling KH, Kok CH, Carolan J, Brautigan P, Kenyon R, D'Andrea RJ, Van der Hoek M, Hahn CN, Torpy DJ, Scott HS. Genome-wide gene expression profiling identifies overlap with malignant adrenocortical tumours and novel mechanisms of inefficient steroidogenesis in familial ACTH-independent macronodular adrenal hyperplasia. Endocr Relat Cancer. 2012 Jun; 19(3):L19-23. PMID: 22383426.
    Citations:    Fields:    Translation:Humans
  38. Atshan SS, Shamsudin MN, Lung LT, Ling KH, Sekawi Z, Pei CP, Ghaznavi-Rad E. Improved method for the isolation of RNA from bacteria refractory to disruption, including S. aureus producing biofilm. Gene. 2012 Feb 25; 494(2):219-24. PMID: 22222139.
    Citations: 7     Fields:    Translation:Cells
  39. Ling KH, Brautigan PJ, Hahn CN, Daish T, Rayner JR, Cheah PS, Raison JM, Piltz S, Mann JR, Mattiske DM, Thomas PQ, Adelson DL, Scott HS. Deep sequencing analysis of the developing mouse brain reveals a novel microRNA. BMC Genomics. 2011 Apr 05; 12:176. PMID: 21466694.
    Citations: 22     Fields:    Translation:Animals
  40. Ling KH, Hewitt CA, Beissbarth T, Hyde L, Cheah PS, Smyth GK, Tan SS, Hahn CN, Thomas T, Thomas PQ, Scott HS. Spatiotemporal regulation of multiple overlapping sense and novel natural antisense transcripts at the Nrgn and Camk2n1 gene loci during mouse cerebral corticogenesis. Cereb Cortex. 2011 Mar; 21(3):683-97. PMID: 20693275.
    Citations: 13     Fields:    Translation:AnimalsCells
  41. Brown CY, Sadlon T, Gargett T, Melville E, Zhang R, Drabsch Y, Ling M, Strathdee CA, Gonda TJ, Barry SC. Robust, reversible gene knockdown using a single lentiviral short hairpin RNA vector. Hum Gene Ther. 2010 Aug; 21(8):1005-17. PMID: 20615123.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  42. Hewitt CA, Ling KH, Merson TD, Simpson KM, Ritchie ME, King SL, Pritchard MA, Smyth GK, Thomas T, Scott HS, Voss AK. Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome. PLoS One. 2010 Jul 16; 5(7):e11561. PMID: 20661276.
    Citations: 12     Fields:    Translation:AnimalsCells
  43. Ling KH, Hewitt CA, Beissbarth T, Hyde L, Banerjee K, Cheah PS, Cannon PZ, Hahn CN, Thomas PQ, Smyth GK, Tan SS, Thomas T, Scott HS. Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Genome Biol. 2009; 10(10):R104. PMID: 19799774.
    Citations: 19     Fields:    Translation:AnimalsCells
  44. Gagliardi L, Hotu C, Casey G, Braund WJ, Ling KH, Dodd T, Manavis J, Devitt PG, Cutfield R, Rudzki Z, Scott HS, Torpy DJ. Familial vasopressin-sensitive ACTH-independent macronodular adrenal hyperplasia (VPs-AIMAH): clinical studies of three kindreds. Clin Endocrinol (Oxf). 2009 Jun; 70(6):883-91. PMID: 19018784.
    Citations: 6     Fields:    Translation:Humans
  45. Ling KH, Rajandream MA, Rivailler P, Ivens A, Yap SJ, Madeira AM, Mungall K, Billington K, Yee WY, Bankier AT, Carroll F, Durham AM, Peters N, Loo SS, Isa MN, Novaes J, Quail M, Rosli R, Nor Shamsudin M, Sobreira TJ, Tivey AR, Wai SF, White S, Wu X, Kerhornou A, Blake D, Mohamed R, Shirley M, Gruber A, Berriman M, Tomley F, Dear PH, Wan KL. Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization. Genome Res. 2007 Mar; 17(3):311-9. PMID: 17284678.
    Citations: 23     Fields:    Translation:AnimalsCells
  46. Ling KH, Loo SS, Rosli R, Shamsudin MN, Mohamed R, Wan KL. In silico identification and characterization of a putative phosphatidylinositol 4-phosphate 5-kinase (PIP5K) gene in Eimeria tenella. In Silico Biol. 2007; 7(1):115-21. PMID: 17688436.
    Citations: 1     Fields:    Translation:AnimalsCells
  47. Say YH, Ling KH, Duraisamy G, Isaac S, Rosli R. Angiotensinogen M235T gene variants and its association with essential hypertension and plasma renin activity in Malaysian subjects: a case control study. BMC Cardiovasc Disord. 2005 Apr 05; 5(1):7. PMID: 15811183.
    Citations: 7     Fields:    Translation:Humans
  48. Ling KH, Rosli R, Duraisamy G, Nasir MT. The prevalence of MTHFR 677C-->T missense mutation, total plasma homocysteine levels and associated risk factors in Malay subjects. Med J Malaysia. 2003 Jun; 58(2):243-54. PMID: 14569745.
    Citations:    Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Ling's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (235)
Explore
_
Co-Authors (3)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.