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Dario Lemos, Ph.D.

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Biography
University of British Columbia, Canada01/2015Tissue regeneration
Oregon Health and Science University, USPh.D.11/2008Molecular physiology
Biogen, US10/2016Tissue injury and regeneration
2004 - 2005
Fogarty International Scholarship
2001 - 2002
Undergraduate Student Research Scholarship
2019 - 2019
Department of Medicine Chair's Research Award

Overview
Biomedical researcher with expertise in mechanisms of tissue regeneration and stem cell biology

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK124301 (LEMOS, DARIO) Apr 9, 2020 - Mar 31, 2023
    NIH
    Inflammatory Signaling in Kidney Stromal Cells Driving Interstitial Fibrosis
    Role: Principal Investigator
  2. R21AG058159 (LEMOS, DARIO) Jul 1, 2018 - Mar 31, 2020
    NIH
    Detection of aging mechanisms of nephron degeneration using nanoscale pathology
    Role Description: The goal of this project is to test, in collaboration with the MIT Media Lab, the use of Expansion Microscopy for the early detection of aging-associated changes in the nephron microenvironment in relation to the adoption of a secretory senescent phenotype in epithelial cells of the proximal tubule
    Role: Principal Investigator
  3. (Dario R. Lemos) May 18, 2018 - Nov 29, 2019
    Astellas Pharma US
    Bioengineered tissues for kidney regeneration in acute and chronic kidney injury
    Role Description: The goal of these studies is to test a series of procedures for the establishment of a kidney regeneration protocol using progenitor cells derived from human pluripotent stem cells.
    Role: Principal Investigator
  4. (Fabio M. V. Rossi) Sep 1, 2012 - Sep 1, 2015
    Heart and Stroke Foundation of Canada
    Characterization and therapeutic potential of fibroadipogenic progenitors
    Role Description: The main goal was to study the interactions between adipocyte progenitors and inflammatory innate immune cells in the context of metabolic syndrome. Specifically, the aim to study how secretion of TGF? by anti-inflammatory macrophages could regulate adipose depot growth by stimulating the proliferation of progenitor cells, supporting hyperplasia over hypertrophy, and therefore exerting a beneficial effect. The results were published in the journals Nature Medicine and Stem Cells.
    Role: Co-Investigator (Co-author)
  5. (Dario Lemos) Jul 1, 2010 - Jul 1, 2011
    Canadian Institutes of Health Research
    Effect of Imatinib mesylate (GleevecĀ®) on sarcopenia-associated fibrofatty muscle degeneration
    Role Description: The goal of the study was to explore the effect of Gleevec treatment on aging-associated ectopic intramuscular connective tissue accumulation in mice. The results were published in the journal Stem Cell Research.
    Role: Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.