Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Onur Dagliyan, Ph.D.

Title
Institution
Department
Address
Phone

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wu HD, Kikuchi M, Dagliyan O, Aragaki AK, Nakamura H, Dokholyan NV, Umehara T, Inoue T. Rational design and implementation of a chemically inducible heterotrimerization system. Nat Methods. 2020 Sep; 17(9):928-936. PMID: 32747768.
    Citations:    
  2. Ozkan-Dagliyan I, Diehl JN, George SD, Schaefer A, Papke B, Klotz-Noack K, Waters AM, Goodwin CM, Gautam P, Pierobon M, Peng S, Gilbert TSK, Lin KH, Dagliyan O, Wennerberg K, Petricoin EF, Tran NL, Bhagwat SV, Tiu RV, Peng SB, Herring LE, Graves LM, Sers C, Wood KC, Cox AD, Der CJ. Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers. Cell Rep. 2020 Jun 16; 31(11):107764. PMID: 32553168.
    Citations:    
  3. Dagliyan O, Dokholyan NV, Hahn KM. Engineering proteins for allosteric control by light or ligands. Nat Protoc. 2019 06; 14(6):1863-1883. PMID: 31076662.
    Citations:    
  4. Dagliyan O, Hahn KM. Controlling protein conformation with light. Curr Opin Struct Biol. 2019 08; 57:17-22. PMID: 30849716.
    Citations:    
  5. Dagliyan O, Krokhotin A, Ozkan-Dagliyan I, Deiters A, Der CJ, Hahn KM, Dokholyan NV. Computational design of chemogenetic and optogenetic split proteins. Nat Commun. 2018 10 02; 9(1):4042. PMID: 30279442.
    Citations:    Fields:    
  6. Ma X, Dagliyan O, Hahn KM, Danuser G. Profiling cellular morphodynamics by spatiotemporal spectrum decomposition. PLoS Comput Biol. 2018 08; 14(8):e1006321. PMID: 30071020.
    Citations:    Fields:    Translation:AnimalsCells
  7. Dagliyan O, Karginov AV, Yagishita S, Gale ME, Wang H, DerMardirossian C, Wells CM, Dokholyan NV, Kasai H, Hahn KM. Engineering Pak1 Allosteric Switches. ACS Synth Biol. 2017 07 21; 6(7):1257-1262. PMID: 28365983.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. Dagliyan O, Tarnawski M, Chu PH, Shirvanyants D, Schlichting I, Dokholyan NV, Hahn KM. Engineering extrinsic disorder to control protein activity in living cells. Science. 2016 12 16; 354(6318):1441-1444. PMID: 27980211.
    Citations: 13     Fields:    Translation:HumansCells
  9. Hodgson L, Spiering D, Sabouri-Ghomi M, Dagliyan O, DerMardirossian C, Danuser G, Hahn KM. FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions. Nat Chem Biol. 2016 10; 12(10):802-809. PMID: 27501396.
    Citations: 3     Fields:    Translation:HumansCells
  10. Shobair M, Dagliyan O, Kota P, Dang YL, He H, Stutts MJ, Dokholyan NV. Gain-of-Function Mutation W493R in the Epithelial Sodium Channel Allosterically Reconfigures Intersubunit Coupling. J Biol Chem. 2016 Feb 19; 291(8):3682-92. PMID: 26668308.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Chu PH, Tsygankov D, Berginski ME, Dagliyan O, Gomez SM, Elston TC, Karginov AV, Hahn KM. Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms. Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34):12420-5. PMID: 25118278.
    Citations: 12     Fields:    Translation:AnimalsCells
  12. Furukawa Y, Teraguchi S, Ikegami T, Dagliyan O, Jin L, Hall D, Dokholyan NV, Namba K, Akira S, Kurosaki T, Baba Y, Standley DM. Intrinsic disorder mediates cooperative signal transduction in STIM1. J Mol Biol. 2014 May 15; 426(10):2082-97. PMID: 24650897.
    Citations: 3     Fields:    Translation:AnimalsCells
  13. Redler RL, Shirvanyants D, Dagliyan O, Ding F, Kim DN, Kota P, Proctor EA, Ramachandran S, Tandon A, Dokholyan NV. Computational approaches to understanding protein aggregation in neurodegeneration. J Mol Cell Biol. 2014 Apr; 6(2):104-15. PMID: 24620031.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  14. Freeman TC, Black JL, Bray HG, Dagliyan O, Wu YI, Tripathy A, Dokholyan NV, Leisner TM, Parise LV. Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity. Biochemistry. 2013 Oct 08; 52(40):7082-90. PMID: 24011356.
    Citations: 6     Fields:    Translation:Cells
  15. Kummer L, Hsu CW, Dagliyan O, MacNevin C, Kaufholz M, Zimmermann B, Dokholyan NV, Hahn KM, Plückthun A. Knowledge-based design of a biosensor to quantify localized ERK activation in living cells. Chem Biol. 2013 Jun 20; 20(6):847-56. PMID: 23790495.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  16. Dagliyan O, Shirvanyants D, Karginov AV, Ding F, Fee L, Chandrasekaran SN, Freisinger CM, Smolen GA, Huttenlocher A, Hahn KM, Dokholyan NV. Rational design of a ligand-controlled protein conformational switch. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6800-4. PMID: 23569285.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  17. Çakir B, Dagliyan O, Dagyildiz E, Baris I, Kavakli IH, Kizilel S, Türkay M. Structure based discovery of small molecules to regulate the activity of human insulin degrading enzyme. PLoS One. 2012; 7(2):e31787. PMID: 22355395.
    Citations: 4     Fields:    Translation:HumansCells
  18. Dagliyan O, Proctor EA, D'Auria KM, Ding F, Dokholyan NV. Structural and dynamic determinants of protein-peptide recognition. Structure. 2011 Dec 07; 19(12):1837-45. PMID: 22153506.
    Citations: 25     Fields:    Translation:Cells
  19. Dagliyan O, Uney-Yuksektepe F, Kavakli IH, Turkay M. Optimization based tumor classification from microarray gene expression data. PLoS One. 2011 Feb 04; 6(2):e14579. PMID: 21326602.
    Citations: 16     Fields:    Translation:Humans
  20. Dagliyan O, Kavakli IH, Turkay M. Classification of cytochrome P450 inhibitors with respect to binding free energy and pIC50 using common molecular descriptors. J Chem Inf Model. 2009 Oct; 49(10):2403-11. PMID: 19777996.
    Citations: 4     Fields:    Translation:HumansCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Dagliyan's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (115)
Explore
_
Co-Authors (1)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.