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Philipp Lirk, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hötschl F, Lirk P, Marti F. [Failure of local anesthesia : Technical inadequacy or true resistance?] Anaesthesiologie. 2023 02; 72(2):106-108. PMID: 36474080.
  2. Kasiri MM, Mittlboek M, Giurgea GA, Fortner N, Lirk P, Eilenberg W, Gollackner B, Neumayer C. Peripheral Artery Disease Causes More Harm to Patients than COVID-19. Healthcare (Basel). 2022 Sep 20; 10(10). PMID: 36292256; PMCID: PMC9602415.
    Citations: 1     
  3. Lirk P, Vlassakov K. Orthopedic Anesthesiology 2022. Anesthesiol Clin. 2022 09; 40(3):xv-xvi. PMID: 36049883.
    Citations:    Fields:    Translation:Humans
  4. Stone A, Lirk P, Vlassakov K. Rebound Pain After Peripheral Nerve Blockade-Bad Timing or Rude Awakening? Anesthesiol Clin. 2022 Sep; 40(3):445-454. PMID: 36049873.
    Citations:    Fields:    Translation:Humans
  5. O'Neill A, Lirk P. Multimodal Analgesia. Anesthesiol Clin. 2022 Sep; 40(3):455-468. PMID: 36049874.
    Citations: 2     Fields:    Translation:Humans
  6. Chen YK, Lirk P, Flowers KM, Colebaugh CA, Wilson JM, Zeballos J, Von Keudell A, Barrett KE, Vlassakov K, Schreiber KL. Impact of varying degrees of peripheral nerve blockade on experimental pressure and ischemic pain: adductor canal and sciatic nerve blocks in a human model of compartment syndrome pain. Reg Anesth Pain Med. 2022 Jul 20. PMID: 35858717.
    Citations: 1     Fields:    
  7. Cooper L, Lirk P, Bader A, Javedan H. Efficiency in Elderhood. Anesth Analg. 2022 08 01; 135(2):435-437. PMID: 35839500.
    Citations:    Fields:    
  8. Kampf S, Willegger M, Dawoud C, Fülöp G, Lirk P, Willfort-Ehringer A, Neumayer C, Gollackner B. Long-term outcome in pediatric surgical bypass grafting after traumatic injury and tumor resection: retrospective cohort analysis. Sci Rep. 2021 08 11; 11(1):16321. PMID: 34381065; PMCID: PMC8357780.
    Citations: 2     Fields:    Translation:Humans
  9. Panzenbeck P, von Keudell A, Joshi GP, Xu CX, Vlassakov K, Schreiber KL, Rathmell JP, Lirk P. Procedure-specific acute pain trajectory after elective total hip arthroplasty: systematic review and data synthesis. Br J Anaesth. 2021 07; 127(1):110-132. PMID: 34147158.
    Citations: 3     Fields:    Translation:Humans
  10. Chin KJ, Lirk P, Hollmann MW, Schwarz SKW. Mechanisms of action of fascial plane blocks: a narrative review. Reg Anesth Pain Med. 2021 07; 46(7):618-628. PMID: 34145073.
    Citations: 9     Fields:    Translation:Humans
  11. Anger M, Valovska T, Beloeil H, Lirk P, Joshi GP, Van de Velde M, Raeder J. PROSPECT guideline for total hip arthroplasty: a systematic review and procedure-specific postoperative pain management recommendations. Anaesthesia. 2021 08; 76(8):1082-1097. PMID: 34015859.
    Citations: 17     Fields:    Translation:Humans
  12. Pancaro C, Kheterpal S, Lirk P. In Response. Anesth Analg. 2021 05 01; 132(5):e81-e82. PMID: 33858000.
    Citations:    Fields:    
  13. Lirk P, El-Boghdadly K. Using ultrasound for nerve blocks and neuraxial anaesthesia: The PERSEUS guidelines. Eur J Anaesthesiol. 2021 03 01; 38(3):215-218. PMID: 33538430.
    Citations:    Fields:    Translation:Humans
  14. Bos EM, van der Lee K, Haumann J, de Quelerij M, Vandertop WP, Kalkman CJ, Hollmann MW, Lirk P. Intracranial hematoma and abscess after neuraxial analgesia and anesthesia: a review of the literature describing 297 cases. Reg Anesth Pain Med. 2021 04; 46(4):337-343. PMID: 33441431.
    Citations: 1     Fields:    Translation:Humans
  15. Jablonski S, Lirk P. Future in regional anesthesia and pain medicine: the pharmacological view. Minerva Anestesiol. 2021 03; 87(3):351-357. PMID: 33432792.
    Citations: 1     Fields:    Translation:Humans
  16. Georgiadis PL, Vlassakov KV, Patton ME, Lirk PB, Janfaza DR, Zeballos JL, Quaye AN, Patel V, Schreiber KL. Ultrasound-guided supraclavicular vs. retroclavicular block of the brachial plexus: comparison of ipsilateral diaphragmatic function: A randomised clinical trial. Eur J Anaesthesiol. 2021 01; 38(1):64-72. PMID: 32925256.
    Citations:    Fields:    Translation:Humans
  17. Pancaro C, Shah N, Pasma W, Saager L, Cassidy R, van Klei W, Kooij F, Vittali D, Hollmann MW, Kheterpal S, Lirk P. Risk of Major Complications After Perioperative Norepinephrine Infusion Through Peripheral Intravenous Lines in a Multicenter Study. Anesth Analg. 2020 10; 131(4):1060-1065. PMID: 32925324.
    Citations: 9     Fields:    Translation:Humans
  18. Bos EME, Posner KL, Domino KB, de Quelerij M, Kalkman CJ, Hollmann MW, Lirk P. Haematoma, abscess or meningitis after neuraxial anaesthesia in the USA and the Netherlands: A closed claims analysis. Eur J Anaesthesiol. 2020 Sep; 37(9):743-751. PMID: 32769504.
    Citations: 2     Fields:    Translation:Humans
  19. Ridderikhof ML, Lodder DV, Van Dieren S, Lirk P, Goddijn H, Goslings JC, Hollmann MW. The relationship between patient factors and the refusal of analgesics in adult Emergency Department patients with extremity injuries, a case-control study. Scand J Pain. 2019 12 18; 20(1):87-94. PMID: 31536036.
    Citations: 1     Fields:    Translation:Humans
  20. Posthuma LM, Visscher MJ, Lirk PB, van Dijkum EJMN, Hollmann MW, Preckel B. Insights into postoperative respiration by using continuous wireless monitoring of respiratory rate on the postoperative ward: a cohort study. J Clin Monit Comput. 2020 Dec; 34(6):1285-1293. PMID: 31722079.
    Citations: 6     Fields:    Translation:Humans
  21. Steen T, Lirk PB, Sigurdsson MI. The demographics of persistent opioid consumption following limb amputation. Acta Anaesthesiol Scand. 2020 03; 64(3):361-367. PMID: 31650532.
    Citations: 4     Fields:    Translation:Humans
  22. Pancaro C, Shah N, Pasma W, Saager L, Cassidy R, van Klei W, Kooij F, Vittali D, Hollmann MW, Kheterpal S, Lirk P. Risk of Major Complications After Perioperative Norepinephrine Infusion Through Peripheral Intravenous Lines in a Multicenter Study. Anesth Analg. 2019 Sep 27. PMID: 31569163.
  23. Hermanns H, Hollmann MW, Stevens MF, Lirk P, Brandenburger T, Piegeler T, Werdehausen R. Molecular mechanisms of action of systemic lidocaine in acute and chronic pain: a narrative review. Br J Anaesth. 2019 Sep; 123(3):335-349. PMID: 31303268.
    Citations: 55     Fields:    Translation:HumansCells
  24. Ridderikhof ML, Saanen J, Goddijn H, Van Dieren S, Van Etten-Jamaludin F, Lirk P, Goslings JC, Hollmann MW. Paracetamol versus other analgesia in adult patients with minor musculoskeletal injuries: a systematic review. Emerg Med J. 2019 Aug; 36(8):493-500. PMID: 31230039.
    Citations: 3     Fields:    Translation:Humans
  25. Hollmann MW, Rathmell JP, Lirk P. Optimal postoperative pain management: redefining the role for opioids. Lancet. 2019 04 13; 393(10180):1483-1485. PMID: 30983573.
    Citations: 14     Fields:    Translation:Humans
  26. Lirk P, Rathmell JP. Opioid-free anaesthesia: Con: it is too early to adopt opioid-free anaesthesia today. Eur J Anaesthesiol. 2019 04; 36(4):250-254. PMID: 30817360.
    Citations: 9     Fields:    
  27. Zinboonyahgoon N, Vlassakov K, Lirk P, Spivey T, King T, Dominici L, Golshan M, Strichartz G, Edwards R, Schreiber K. Benefit of regional anaesthesia on postoperative pain following mastectomy: the influence of catastrophising. Br J Anaesth. 2019 08; 123(2):e293-e302. PMID: 31331591; PMCID: PMC6676159.
    Citations: 11     Fields:    Translation:Humans
  28. Ridderikhof ML, De Kruif E, Stevens MF, Baumann HM, Lirk PB, Goslings JC, Hollmann MW. Ultrasound guided supra-inguinal Fascia Iliaca Compartment Blocks in hip fracture patients: An alternative technique. Am J Emerg Med. 2020 02; 38(2):231-236. PMID: 30770243.
    Citations: 3     Fields:    Translation:Humans
  29. Lirk P, Thiry J, Bonnet MP, Joshi GP, Bonnet F. Pain management after laparoscopic hysterectomy: systematic review of literature and PROSPECT recommendations. Reg Anesth Pain Med. 2019 04; 44(4):425-436. PMID: 30914471.
    Citations: 8     Fields:    Translation:Humans
  30. Mungroop TH, Bond MJ, Lirk P, Busch OR, Hollmann MW, Veelo DP, Besselink MG. Preperitoneal or Subcutaneous Wound Catheters as Alternative for Epidural Analgesia in Abdominal Surgery: A Systematic Review and Meta-analysis. Ann Surg. 2019 02; 269(2):252-260. PMID: 29781846.
    Citations: 14     Fields:    Translation:Humans
  31. Zivkovic N, van Samkar G, Hermanns H, Lirk P, Hollmann MW, van den Dobbelsteen JJ, van Gerwen DJ, Stevens MF. Face and construct validity of TU-Delft epidural simulator and the value of real-time visualization. Reg Anesth Pain Med. 2019 Mar; 44(3):298-302. PMID: 30674695.
    Citations: 1     Fields:    
  32. Hulst AH, Polderman JAW, Kooij FO, Vittali D, Lirk P, Hollmann MW, DeVries JH, Preckel B, Hermanides J. Comparison of perioperative glucose regulation in patients with type 1 vs type 2 diabetes mellitus: A retrospective cross-sectional study. Acta Anaesthesiol Scand. 2019 03; 63(3):314-321. PMID: 30357807.
    Citations:    Fields:    Translation:Humans
  33. Lirk P, Brummett CM. Regional anaesthesia, diabetic neuropathy, and dexmedetomidine: a neurotoxic combination? Br J Anaesth. 2019 01; 122(1):16-18. PMID: 30579401.
    Citations: 5     Fields:    Translation:Animals
  34. Barrington MJ, Lirk P. Reducing the risk of neurological complications after peripheral nerve block: what is the role of pressure monitoring? Anaesthesia. 2019 Jan; 74(1):9-12. PMID: 30339281.
    Citations: 2     Fields:    Translation:Humans
  35. Vlassakov K, Lirk P, Rathmell JP. Intraneural Injection: Is the Jury Still Out? Anesthesiology. 2018 08; 129(2):221-224. PMID: 29933286.
    Citations: 1     Fields:    
  36. Bos EME, Schut ME, de Quelerij M, Kalkman CJ, Hollmann MW, Lirk P. Trends in practice and safety measures of epidural analgesia: Report of a national survey. Acta Anaesthesiol Scand. 2018 11; 62(10):1466-1472. PMID: 30066960.
    Citations: 3     Fields:    Translation:Humans
  37. Zeballos JL, Lirk P, Rathmell JP. Low-Dose Ketamine for Acute Pain Management: A Timely Nudge Toward Multimodal Analgesia. Reg Anesth Pain Med. 2018 07; 43(5):453-455. PMID: 29927846.
    Citations: 4     Fields:    Translation:Humans
  38. Lirk P, Hollmann MW, Strichartz G. The Science of Local Anesthesia: Basic Research, Clinical Application, and Future Directions. Anesth Analg. 2018 04; 126(4):1381-1392. PMID: 29189280.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  39. Ten Hoope W, Hollmann MW, de Bruin K, Verberne HJ, Verkerk AO, Tan HL, Verhamme C, Horn J, Rigaud M, Picardi S, Lirk P. Pharmacodynamics and Pharmacokinetics of Lidocaine in a Rodent Model of Diabetic Neuropathy. Anesthesiology. 2018 03; 128(3):609-619. PMID: 29251644.
    Citations: 6     Fields:    Translation:Animals
  40. Bos EME, Haumann J, de Quelerij M, Vandertop WP, Kalkman CJ, Hollmann MW, Lirk P. Haematoma and abscess after neuraxial anaesthesia: a review of 647 cases. Br J Anaesth. 2018 Apr; 120(4):693-704. PMID: 29576110.
    Citations: 12     Fields:    Translation:Humans
  41. Bos EME, Hollmann MW, Lirk P. Safety and efficacy of epidural analgesia. Curr Opin Anaesthesiol. 2017 Dec; 30(6):736-742. PMID: 28938298.
    Citations: 19     Fields:    Translation:Humans
  42. van Samkar G, Hermanns H, Lirk P, Hollmann MW, Stevens MF. Influence on number of top-ups after implementing patient controlled epidural analgesia: A cohort study. PLoS One. 2017; 12(10):e0186225. PMID: 29045482.
    Citations:    Fields:    Translation:Humans
  43. Ridderikhof ML, Lirk P, Goddijn H, Vandewalle E, Schinkel E, Van Dieren S, Kemper EM, Hollmann MW, Goslings JC. Acetaminophen or Nonsteroidal Anti-Inflammatory Drugs in Acute Musculoskeletal Trauma: A Multicenter, Double-Blind, Randomized, Clinical Trial. Ann Emerg Med. 2018 03; 71(3):357-368.e8. PMID: 29033294.
    Citations: 5     Fields:    Translation:Humans
  44. Ten Hoope W, Looije M, Lirk P. Regional anesthesia in diabetic peripheral neuropathy. Curr Opin Anaesthesiol. 2017 Oct; 30(5):627-631. PMID: 28719457.
    Citations: 5     Fields:    Translation:Humans
  45. Jones MR, Hadley GR, Kaye AD, Lirk P, Urman RD. Paravertebral Blocks for Same-Day Breast Surgery. Curr Pain Headache Rep. 2017 Aug; 21(8):35. PMID: 28664348.
    Citations: 2     Fields:    Translation:Humans
  46. Mungroop TH, van Samkar G, Geerts BF, van Dieren S, Besselink MG, Veelo DP, Lirk P. Serum levels of bupivacaine after pre-peritoneal bolus vs. epidural bolus injection for analgesia in abdominal surgery: A safety study within a randomized controlled trial. PLoS One. 2017; 12(6):e0178917. PMID: 28614364.
    Citations:    Fields:    Translation:Humans
  47. Lee LO, Bateman BT, Kheterpal S, Klumpner TT, Housey M, Aziz MF, Hand KW, MacEachern M, Goodier CG, Bernstein J, Bauer ME. Risk of Epidural Hematoma after Neuraxial Techniques in Thrombocytopenic Parturients: A Report from the Multicenter Perioperative Outcomes Group. Anesthesiology. 2017 06; 126(6):1053-1063. PMID: 28383323; PMCID: PMC5445642.
    Citations: 37     Fields:    Translation:Humans
  48. Sekandarzad MW, van Zundert AAJ, Lirk PB, Doornebal CW, Hollmann MW. Perioperative Anesthesia Care and Tumor Progression. Anesth Analg. 2017 05; 124(5):1697-1708. PMID: 27828796.
    Citations: 55     Fields:    Translation:Humans
  49. Rahiri J, Tuhoe J, Svirskis D, Lightfoot NJ, Lirk PB, Hill AG. Systematic review of the systemic concentrations of local anaesthetic after transversus abdominis plane block and rectus sheath block. Br J Anaesth. 2017 Apr 01; 118(4):517-526. PMID: 28403398.
    Citations: 11     Fields:    Translation:Humans
  50. Ten Hoope W, Hollmann MW, Atchabahian A, Rigaud M, Kerkhoffs GM, Lirk P, Baumann HM. Minimum local anesthetic volumes for a selective saphenous nerve block: a dose-finding study. Minerva Anestesiol. 2017 Feb; 83(2):183-190. PMID: 27834474.
    Citations:    Fields:    Translation:Humans
  51. Ridderikhof ML, Schyns FJ, Schep NW, Lirk P, Hollmann MW, Goslings JC. Emergency Department Pain Management in Adult Patients With Traumatic Injuries Before and After Implementation of a Nurse-Initiated Pain Treatment Protocol Utilizing Fentanyl for Severe Pain. J Emerg Med. 2017 Apr; 52(4):417-425. PMID: 27650720.
    Citations: 4     Fields:    Translation:Humans
  52. Mungroop TH, Veelo DP, Busch OR, van Dieren S, van Gulik TM, Karsten TM, de Castro SM, Godfried MB, Thiel B, Hollmann MW, Lirk P, Besselink MG. Continuous wound infiltration versus epidural analgesia after hepato-pancreato-biliary surgery (POP-UP): a randomised controlled, open-label, non-inferiority trial. Lancet Gastroenterol Hepatol. 2016 10; 1(2):105-113. PMID: 28404067.
    Citations: 13     Fields:    Translation:Humans
  53. Heschl S, Hallmann B, Zilke T, Gemes G, Schoerghuber M, Auer-Grumbach M, Quehenberger F, Lirk P, Hogan Q, Rigaud M. Diabetic neuropathy increases stimulation threshold during popliteal sciatic nerve block. Br J Anaesth. 2016 Apr; 116(4):538-45. PMID: 26994231.
    Citations: 2     Fields:    Translation:Humans
  54. Ridderikhof ML, Leenders N, Goddijn H, Schep NW, Lirk P, Goslings JC, Hollmann MW. Anesthesia with topical lidocaine hydrochloride gauzes in acute traumatic wounds in triage, a pilot study. Int Emerg Nurs. 2016 Sep; 28:25-8. PMID: 27036930.
    Citations:    Fields:    Translation:Humans
  55. Verlinde M, Hollmann MW, Stevens MF, Hermanns H, Werdehausen R, Lirk P. Local Anesthetic-Induced Neurotoxicity. Int J Mol Sci. 2016 Mar 04; 17(3):339. PMID: 26959012.
    Citations: 48     Fields:    Translation:Cells
  56. Reina MA, Lirk P, Puigdellívol-Sánchez A, Mavar M, Prats-Galino A. Human Lumbar Ligamentum Flavum Anatomy for Epidural Anesthesia: Reviewing a 3D MR-Based Interactive Model and Postmortem Samples. Anesth Analg. 2016 Mar; 122(3):903-907. PMID: 26891398.
    Citations: 6     Fields:    Translation:Humans
  57. Piegeler T, Hollmann MW, Borgeat A, Lirk P. Do Amide Local Anesthetics Play a Therapeutic Role in the Perioperative Management of Cancer Patients? Int Anesthesiol Clin. 2016; 54(4):e17-32. PMID: 27602709.
    Citations: 8     Fields:    Translation:Humans
  58. Mungroop TH, Veelo DP, Busch OR, van Dieren S, van Gulik TM, Karsten TM, de Castro SM, Godfried MB, Thiel B, Hollmann MW, Lirk P, Besselink MG. Continuous wound infiltration or epidural analgesia for pain prevention after hepato-pancreato-biliary surgery within an enhanced recovery program (POP-UP trial): study protocol for a randomized controlled trial. Trials. 2015 Dec 09; 16:562. PMID: 26654448.
    Citations: 2     Fields:    Translation:Humans
  59. Kirchmair L, Ströhle M, Löscher WN, Kreutziger J, Voelckel WG, Lirk P. Neurophysiological effects of needle trauma and intraneural injection in a porcine model: a pilot study. Acta Anaesthesiol Scand. 2016 Mar; 60(3):393-9. PMID: 26611997.
    Citations: 3     Fields:    Translation:Animals
  60. Picardi S, Lirk P, Blobner M, Schönherr ME, Hollmann MW. [Adjuvants in modern anesthesia - magnesium]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2015 Jun; 50(6):380-7. PMID: 26147407.
    Citations: 1     Fields:    Translation:Humans
  61. Picardi S, Lirk P, Boeckh R, Hollmann MW. [Adjuvants in modern anesthesia - lidocaine]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2015 May; 50(5):322-7. PMID: 26018064.
    Citations: 1     Fields:    Translation:Humans
  62. Lirk P, Fiegl H, Weber NC, Hollmann MW. Epigenetics in the perioperative period. Br J Pharmacol. 2015 Jun; 172(11):2748-55. PMID: 25073649.
    Citations: 16     Fields:    Translation:HumansCells
  63. van Loon AM, Fahrenfort JJ, van der Velde B, Lirk PB, Vulink NC, Hollmann MW, Scholte HS, Lamme VA. NMDA Receptor Antagonist Ketamine Distorts Object Recognition by Reducing Feedback to Early Visual Cortex. Cereb Cortex. 2016 May; 26(5):1986-96. PMID: 25662715.
    Citations: 21     Fields:    Translation:Humans
  64. McDonough J, Lirk P. QTc interval prolongation: a real concern or exaggerated threat? Gastroenterol Nurs. 2014 Nov-Dec; 37(6):446-9. PMID: 25461467.
    Citations:    Fields:    Translation:Humans
  65. Lirk P, Picardi S, Hollmann MW. Local anaesthetics: 10 essentials. Eur J Anaesthesiol. 2014 Nov; 31(11):575-85. PMID: 25192265.
    Citations: 36     Fields:    Translation:HumansAnimals
  66. Lirk P, Verhamme C, Boeckh R, Stevens MF, ten Hoope W, Gerner P, Blumenthal S, de Girolami U, van Schaik IN, Hollmann MW, Picardi S. Effects of early and late diabetic neuropathy on sciatic nerve block duration and neurotoxicity in Zucker diabetic fatty rats. Br J Anaesth. 2015 Feb; 114(2):319-26. PMID: 25145353.
    Citations: 11     Fields:    Translation:Animals
  67. Lirk P, Hollmann MW, Fleischer M, Weber NC, Fiegl H. Lidocaine and ropivacaine, but not bupivacaine, demethylate deoxyribonucleic acid in breast cancer cells in vitro. Br J Anaesth. 2014 Jul; 113 Suppl 1:i32-8. PMID: 24946779.
    Citations: 27     Fields:    Translation:HumansCells
  68. Lirk P, Hollmann MW. Ondansetron: a new therapeutic option to attenuate postoperative cognitive dysfunction and delirium? Minerva Anestesiol. 2014 Apr; 80(4):407-9. PMID: 24257153.
    Citations: 1     Fields:    Translation:Humans
  69. Ridderikhof ML, Lirk P, Schep NW, Hoeberichts A, Goddijn WT, Luitse JS, Kemper EM, Dijkgraaf MG, Hollmann MW, Goslings JC. The PanAM study: a multi-center, double-blinded, randomized, non-inferiority study of paracetamol versus non-steroidal anti-inflammatory drugs in treating acute musculoskeletal trauma. BMC Emerg Med. 2013 Nov 20; 13:19. PMID: 24256450.
    Citations: 2     Fields:    Translation:Humans
  70. Lirk P, Hollmann MW. Outcome after regional anesthesia: weighing risks and benefits. Minerva Anestesiol. 2014 May; 80(5):610-8. PMID: 24193234.
    Citations: 5     Fields:    Translation:Humans
  71. Meuwese JD, van Loon AM, Scholte HS, Lirk PB, Vulink NC, Hollmann MW, Lamme VA. NMDA receptor antagonist ketamine impairs feature integration in visual perception. PLoS One. 2013; 8(11):e79326. PMID: 24223927.
    Citations: 6     Fields:    Translation:Humans
  72. Picardi S, Stevens MF, Hahnenkamp K, Durieux ME, Lirk P, Hollmann MW. Time-dependent modulation of muscarinic m1/m3 receptor signalling by local anaesthetics. Br J Anaesth. 2014 Feb; 112(2):370-9. PMID: 24065730.
    Citations: 3     Fields:    Translation:AnimalsCells
  73. Lirk P, Rutten MV, Haller I, Stevens MF, Laudolff-Birmingham J, Hollmann M, Birmingham B. Management of the patient with diabetic peripheral neuropathy presenting for peripheral regional anesthesia: a European survey and review of literature. Minerva Anestesiol. 2013 Sep; 79(9):1039-48. PMID: 23652172.
    Citations: 4     Fields:    Translation:Humans
  74. Lirk P, Stadlbauer KH, Hollmann MW. ESA Clinical Trials Network 2012: PLATA--Prevention of Phantom Limb Pain After Transtibial Amputation: randomised, double-blind, controlled, multicentre trial comparing optimised intravenous pain control versus optimised intravenous pain control plus regional anaesthesia. Eur J Anaesthesiol. 2013 May; 30(5):202-4. PMID: 23571431.
    Citations: 5     Fields:    Translation:Humans
  75. Picardi S, Cartellieri S, Groves D, Hahnenkamp K, Hahnenekamp K, Gerner P, Durieux ME, Stevens MF, Lirk P, Hollmann MW. Local anesthetic-induced inhibition of human neutrophil priming: the influence of structure, lipophilicity, and charge. Reg Anesth Pain Med. 2013 Jan-Feb; 38(1):9-15. PMID: 23222364.
    Citations: 14     Fields:    Translation:HumansCells
  76. Gemes G, Koopmeiners A, Rigaud M, Lirk P, Sapunar D, Bangaru ML, Vilceanu D, Garrison SR, Ljubkovic M, Mueller SJ, Stucky CL, Hogan QH. Failure of action potential propagation in sensory neurons: mechanisms and loss of afferent filtering in C-type units after painful nerve injury. J Physiol. 2013 Feb 15; 591(4):1111-31. PMID: 23148321.
    Citations: 38     Fields:    Translation:AnimalsCells
  77. Lirk P, Flatz M, Haller I, Hausott B, Blumenthal S, Stevens MF, Suzuki S, Klimaschewski L, Gerner P. In Zucker diabetic fatty rats, subclinical diabetic neuropathy increases in vivo lidocaine block duration but not in vitro neurotoxicity. Reg Anesth Pain Med. 2012 Nov-Dec; 37(6):601-6. PMID: 23011115.
    Citations: 11     Fields:    Translation:AnimalsCells
  78. Lirk P, Haller I, Wong CA. Management of spinal anaesthesia-induced hypotension for caesarean delivery: a European survey. Eur J Anaesthesiol. 2012 Sep; 29(9):452-3. PMID: 22472628.
    Citations: 4     Fields:    Translation:Humans
  79. Hermanides J, Hollmann MW, Stevens MF, Lirk P. Failed epidural: causes and management. Br J Anaesth. 2012 Aug; 109(2):144-54. PMID: 22735301.
    Citations: 100     Fields:    Translation:Humans
  80. Lirk P, Berger R, Hollmann MW, Fiegl H. Lidocaine time- and dose-dependently demethylates deoxyribonucleic acid in breast cancer cell lines in vitro. Br J Anaesth. 2012 Aug; 109(2):200-7. PMID: 22542536.
    Citations: 49     Fields:    Translation:HumansCells
  81. Lirk P, Birmingham B, Hogan Q. Regional anesthesia in patients with preexisting neuropathy. Int Anesthesiol Clin. 2011; 49(4):144-65. PMID: 21956084.
    Citations: 15     Fields:    Translation:HumansAnimals
  82. Lirk P, Kleber N, Mitterschiffthaler G, Keller C, Benzer A, Putz G. Pulmonary effects of bupivacaine, ropivacaine, and levobupivacaine in parturients undergoing spinal anaesthesia for elective caesarean delivery: a randomised controlled study. Int J Obstet Anesth. 2010 Jul; 19(3):287-92. PMID: 20605441.
    Citations: 5     Fields:    Translation:Humans
  83. Rigaud M, Filip P, Lirk P, Fuchs A, Gemes G, Hogan Q. Guidance of block needle insertion by electrical nerve stimulation: a pilot study of the resulting distribution of injected solution in dogs. Anesthesiology. 2008 Sep; 109(3):473-8. PMID: 18719445; PMCID: PMC2700062.
    Citations: 9     Fields:    Translation:Animals
  84. Hogan Q, Lirk P, Poroli M, Rigaud M, Fuchs A, Fillip P, Ljubkovic M, Gemes G, Sapunar D. Restoration of calcium influx corrects membrane hyperexcitability in injured rat dorsal root ganglion neurons. Anesth Analg. 2008 Sep; 107(3):1045-51. PMID: 18713927; PMCID: PMC2700057.
    Citations: 20     Fields:    Translation:AnimalsCells
  85. Lirk P, Poroli M, Rigaud M, Fuchs A, Fillip P, Huang CY, Ljubkovic M, Sapunar D, Hogan Q. Modulators of calcium influx regulate membrane excitability in rat dorsal root ganglion neurons. Anesth Analg. 2008 Aug; 107(2):673-85. PMID: 18633052; PMCID: PMC2872162.
    Citations: 29     Fields:    Translation:AnimalsCells
  86. Schmutzhard J, Rieder J, Deibl M, Schwentner IM, Schmid S, Lirk P, Abraham I, Gunkel AR. Pilot study: volatile organic compounds as a diagnostic marker for head and neck tumors. Head Neck. 2008 Jun; 30(6):743-9. PMID: 18286484.
    Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
  87. Lirk P, Haller I, Colvin HP, Lang L, Tomaselli B, Klimaschewski L, Gerner P. In vitro, inhibition of mitogen-activated protein kinase pathways protects against bupivacaine- and ropivacaine-induced neurotoxicity. Anesth Analg. 2008 May; 106(5):1456-64, table of contents. PMID: 18420860.
    Citations: 30     Fields:    Translation:AnimalsCells
  88. Kirchmair L, Lirk P, Colvin J, Mitterschiffthaler G, Moriggl B. Lumbar plexus and psoas major muscle: not always as expected. Reg Anesth Pain Med. 2008 Mar-Apr; 33(2):109-14. PMID: 18299090.
    Citations: 15     Fields:    Translation:Humans
  89. Lirk P, Haller I, Colvin HP, Frauscher S, Kirchmair L, Gerner P, Klimaschewski L. In vitro, lidocaine-induced axonal injury is prevented by peripheral inhibition of the p38 mitogen-activated protein kinase, but not by inhibiting caspase activity. Anesth Analg. 2007 Dec; 105(6):1657-64, table of contents. PMID: 18042864.
    Citations: 8     Fields:    Translation:AnimalsCells
  90. Hung YC, Chen CY, Lirk P, Wang CF, Cheng JK, Chen CC, Wang GK, Gerner P. Magnesium sulfate diminishes the effects of amide local anesthetics in rat sciatic-nerve block. Reg Anesth Pain Med. 2007 Jul-Aug; 32(4):288-95. PMID: 17720112.
    Citations: 10     Fields:    Translation:Animals
  91. Fridrich P, Colvin HP, Zizza A, Wasan AD, Lukanich J, Lirk P, Saria A, Zernig G, Hamp T, Gerner P. Phase 1A safety assessment of intravenous amitriptyline. J Pain. 2007 Jul; 8(7):549-55. PMID: 17512256; PMCID: PMC2001298.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  92. Haller I, Lirk P, Keller C, Wang GK, Gerner P, Klimaschewski L. Differential neurotoxicity of tricyclic antidepressants and novel derivatives in vitro in a dorsal root ganglion cell culture model. Eur J Anaesthesiol. 2007 Aug; 24(8):702-8. PMID: 17437653.
    Citations: 7     Fields:    Translation:Animals
  93. Ong CK, Lirk P, Tan CH, Seymour RA. An evidence-based update on nonsteroidal anti-inflammatory drugs. Clin Med Res. 2007 Mar; 5(1):19-34. PMID: 17456832.
    Citations: 133     Fields:    Translation:Humans
  94. Haller I, Hausott B, Tomaselli B, Keller C, Klimaschewski L, Gerner P, Lirk P. Neurotoxicity of lidocaine involves specific activation of the p38 mitogen-activated protein kinase, but not extracellular signal-regulated or c-jun N-terminal kinases, and is mediated by arachidonic acid metabolites. Anesthesiology. 2006 Nov; 105(5):1024-33. PMID: 17065898.
    Citations: 16     Fields:    Translation:AnimalsCells
  95. Lirk P, Haller I, Myers RR, Klimaschewski L, Kau YC, Hung YC, Gerner P. Mitigation of direct neurotoxic effects of lidocaine and amitriptyline by inhibition of p38 mitogen-activated protein kinase in vitro and in vivo. Anesthesiology. 2006 Jun; 104(6):1266-73. PMID: 16732099.
    Citations: 19     Fields:    Translation:AnimalsCells
  96. Lirk P, Haller I, Hausott B, Ingorokva S, Deibl M, Gerner P, Klimaschewski L. The neurotoxic effects of amitriptyline are mediated by apoptosis and are effectively blocked by inhibition of caspase activity. Anesth Analg. 2006 Jun; 102(6):1728-33. PMID: 16717317.
    Citations: 14     Fields:    Translation:AnimalsCells
  97. Ong KS, Seymour RA, Yeo JF, Ho KH, Lirk P. The efficacy of preoperative versus postoperative rofecoxib for preventing acute postoperative dental pain: a prospective randomized crossover study using bilateral symmetrical oral surgery. Clin J Pain. 2005 Nov-Dec; 21(6):536-42. PMID: 16215339.
    Citations: 4     Fields:    Translation:Humans
  98. Lechner M, Karlseder A, Niederseer D, Lirk P, Neher A, Rieder J, Tilg H. H. pylori infection increases levels of exhaled nitrate. Helicobacter. 2005 Oct; 10(5):385-90. PMID: 16181348.
    Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
  99. Sapunar D, Ljubkovic M, Lirk P, McCallum JB, Hogan QH. Distinct membrane effects of spinal nerve ligation on injured and adjacent dorsal root ganglion neurons in rats. Anesthesiology. 2005 Aug; 103(2):360-76. PMID: 16052119.
    Citations: 58     Fields:    Translation:AnimalsCells
  100. Lechner M, Lirk P, Rieder J. Inducible nitric oxide synthase (iNOS) in tumor biology: the two sides of the same coin. Semin Cancer Biol. 2005 Aug; 15(4):277-89. PMID: 15914026.
    Citations: 130     Fields:    Translation:Humans
  101. Friesenecker BE, Peer R, Rieder J, Lirk P, Knotzer H, Hasibeder WR, Mayr AJ, Dünser MW. Craniotomy during ECMO in a severely traumatized patient. Acta Neurochir (Wien). 2005 Sep; 147(9):993-6; discussion 996. PMID: 16021388.
    Citations: 9     Fields:    Translation:Humans
  102. Fuchs A, Lirk P, Stucky C, Abram SE, Hogan QH. Painful nerve injury decreases resting cytosolic calcium concentrations in sensory neurons of rats. Anesthesiology. 2005 Jun; 102(6):1217-25. PMID: 15915036.
    Citations: 32     Fields:    Translation:AnimalsCells
  103. Lirk P, Colvin J, Steger B, Colvin HP, Keller C, Rieder J, Kolbitsch C, Moriggl B. Incidence of lower thoracic ligamentum flavum midline gaps. Br J Anaesth. 2005 Jun; 94(6):852-5. PMID: 15817710.
    Citations: 11     Fields:    Translation:Humans
  104. Lirk P, Colvin JM, Biebl M, Mitterschiffthaler G, Moser PL, Lorenz IH, Kolbitsch C. [Evaluation of a cadaver workshop for education in regional anesthesia]. Anaesthesist. 2005 Apr; 54(4):327-32. PMID: 15711813.
    Citations: 4     Fields:    Translation:Humans
  105. Ong CK, Lirk P, Seymour RA, Jenkins BJ. The efficacy of preemptive analgesia for acute postoperative pain management: a meta-analysis. Anesth Analg. 2005 Mar; 100(3):757-773. PMID: 15728066.
    Citations: 147     Fields:    Translation:Humans
  106. von Goedecke A, Keller C, Moriggl B, Wenzel V, Bale R, Deibl M, Moser P, Lirk P. An anatomic landmark to simplify subclavian vein cannulation: the "deltoid tuberosity". Anesth Analg. 2005 Mar; 100(3):623-628. PMID: 15728041.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  107. Moser B, Bodrogi F, Eibl G, Lechner M, Rieder J, Lirk P. Mass spectrometric profile of exhaled breath--field study by PTR-MS. Respir Physiol Neurobiol. 2005 Feb 15; 145(2-3):295-300. PMID: 15705543.
    Citations: 28     Fields:    Translation:HumansPHPublic Health
  108. Pinggera GM, Lirk P, Bodogri F, Herwig R, Steckel-Berger G, Bartsch G, Rieder J. Urinary acetonitrile concentrations correlate with recent smoking behaviour. BJU Int. 2005 Feb; 95(3):306-9. PMID: 15679783.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  109. Rieder J, Lirk P, Bodrogi F, Sawires M, Gruber G, Hoffmann G. Cisatracurium, but not mivacurium, induces apoptosis in human umbilical vein endothelial cells in vitro. Eur J Anaesthesiol. 2005 Jan; 22(1):16-9. PMID: 15816567.
    Citations: 7     Fields:    Translation:HumansCells
  110. Keller C, Brimacombe J, von Goedecke A, Lirk P. Airway protection with the ProSeal laryngeal mask airway in a child. Paediatr Anaesth. 2004 Dec; 14(12):1021-2. PMID: 15601353.
    Citations: 2     Fields:    Translation:Humans
  111. Hinteregger M, Zschiegner F, Lirk P, Ladner E, Goeschl A, Gaber O, Moser P, Lorenz I, Kolbitsch C. A new guidance device facilitates percutaneous puncture of the foramen ovale in human cadavers. Can J Anaesth. 2004 Dec; 51(10):990-2. PMID: 15574548.
    Citations: 4     Fields:    Translation:Humans
  112. Moser B, Lirk P, Lechner M, Gottardis M. General anaesthesia in a patient with motor neuron disease. Eur J Anaesthesiol. 2004 Nov; 21(11):921-3. PMID: 15717714.
    Citations: 2     Fields:    Translation:Humans
  113. Keller C, Brimacombe J, Moriggl B, Lirk P, von Goedecke A. In cadavers, directly measured mucosal pressures are similar for the Unique and the Soft Seal laryngeal mask airway devices. Can J Anaesth. 2004 Oct; 51(8):834-7. PMID: 15470175.
    Citations: 2     Fields:    Translation:Humans
  114. Lirk P, Keller C, Colvin J, Rieder J, Wulf K. Anaesthetic management of the Prader-Willi syndrome. Eur J Anaesthesiol. 2004 Oct; 21(10):831-3. PMID: 15678742.
    Citations: 1     Fields:    Translation:Humans
  115. Lirk P, Longato S, Rieder J, Klimaschewski L. Cisatracurium, but not mivacurium, inhibits survival and axonal growth of neonatal and adult rat peripheral neurons in vitro. Neurosci Lett. 2004 Jul 22; 365(2):153-5. PMID: 15245798.
    Citations: 2     Fields:    Translation:AnimalsCells
  116. Keller C, Brimacombe J, Bittersohl J, Lirk P, von Goedecke A. Aspiration and the laryngeal mask airway: three cases and a review of the literature. Br J Anaesth. 2004 Oct; 93(4):579-82. PMID: 15247112.
    Citations: 20     Fields:    Translation:Humans
  117. Dünser MW, Ohlbauer M, Rieder J, Zimmermann I, Ruatti H, Schwabegger AH, Bodrogi F, Huemer GM, Friesenecker BE, Mayr AJ, Lirk P. Critical care management of major hydrofluoric acid burns: a case report, review of the literature, and recommendations for therapy. Burns. 2004 Jun; 30(4):391-8. PMID: 15145201.
    Citations: 8     Fields:    Translation:Humans
  118. Keller C, Brimacombe J, Lirk P, Pühringer F. Failed obstetric tracheal intubation and postoperative respiratory support with the ProSeal laryngeal mask airway. Anesth Analg. 2004 May; 98(5):1467-70, table of contents. PMID: 15105232.
    Citations: 8     Fields:    Translation:Humans
  119. Lirk P, Moriggl B, Colvin J, Keller C, Kirchmair L, Rieder J, Kolbitsch C. The incidence of lumbar ligamentum flavum midline gaps. Anesth Analg. 2004 Apr; 98(4):1178-1180. PMID: 15041621.
    Citations: 4     Fields:    Translation:Humans
  120. Lirk P, Keller C, Colvin J, Colvin H, Rieder J, Maurer H, Moriggl B. Unintentional arterial puncture during cephalic vein cannulation: case report and anatomical study. Br J Anaesth. 2004 May; 92(5):740-2. PMID: 15003983.
    Citations: 8     Fields:    Translation:Humans
  121. Lirk P, Messner H, Deibl M, Mitterschiffthaler G, Colvin J, Steger B, Rieder J, Keller C. Accuracy in estimating the correct intervertebral space level during lumbar, thoracic and cervical epidural anaesthesia. Acta Anaesthesiol Scand. 2004 Mar; 48(3):347-9. PMID: 14982569.
    Citations: 4     Fields:    Translation:Humans
  122. Smolle M, Keller C, Pinggera G, Deibl M, Rieder J, Lirk P. Clear hydro-gel, compared to ointment, provides improved eye comfort after brief surgery. Can J Anaesth. 2004 Feb; 51(2):126-9. PMID: 14766687.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  123. Lirk P, Bodrogi F, Deibl M, Kähler CM, Colvin J, Moser B, Pinggera G, Raifer H, Rieder J, Schobersberger W. Quantification of recent smoking behaviour using proton transfer reaction-mass spectrometry (PTR-MS). Wien Klin Wochenschr. 2004 Jan 31; 116(1-2):21-5. PMID: 15030119.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  124. Lirk P, Kolbitsch C, Putz G, Colvin J, Colvin HP, Lorenz I, Keller C, Kirchmair L, Rieder J, Moriggl B. Cervical and high thoracic ligamentum flavum frequently fails to fuse in the midline. Anesthesiology. 2003 Dec; 99(6):1387-90. PMID: 14639154.
    Citations: 23     Fields:    Translation:Humans
  125. Lirk P, Rieder J, Schuerholz A, Keller C. Anaesthetic implications of Robinow syndrome. Paediatr Anaesth. 2003 Oct; 13(8):725-7. PMID: 14535914.
    Citations:    Fields:    Translation:Humans
  126. Summer G, Lirk P, Hoerauf K, Riccabona U, Bodrogi F, Raifer H, Deibl M, Rieder J, Schobersberger W. Sevoflurane in exhaled air of operating room personnel. Anesth Analg. 2003 Oct; 97(4):1070-1073. PMID: 14500159.
    Citations: 5     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  127. Lirk P, Bodrogi F, Raifer H, Greiner K, Ulmer H, Rieder J. Elective haemodialysis increases exhaled isoprene. Nephrol Dial Transplant. 2003 May; 18(5):937-41. PMID: 12686668.
    Citations: 12     Fields:    Translation:Humans
  128. Lorenz IH, Schubert HM, Lirk P, Moser PL, Hohlrieder M, Schlimp C, Hackl JM, Kolbitsch C. [Evaluation of an established course of hospital management through structured telephone survey of former participants]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2003 May; 38(5):349-58. PMID: 12712400.
    Citations:    Fields:    
  129. Rieder J, Lirk P, Hoffmann G. Neopterin as a potential modulator of tumor cell growth and proliferation. Med Hypotheses. 2003 Apr; 60(4):531-4. PMID: 12615515.
    Citations: 1     Fields:    Translation:HumansCells
  130. Rieder J, Keller C, Hoffmann G, Lirk P. Moscow theatre siege and anaesthetic drugs. Lancet. 2003 Mar 29; 361(9363):1131. PMID: 12672335.
    Citations: 2     Fields:    Translation:Humans
  131. Rieder J, Gruber G, Bodrogi F, Lirk P, Hoffmann G. Anaphylactoid reaction to cisatracurium may be explained by atracurium metabolites. Anesth Analg. 2003 Jan; 96(1):301; author reply 301. PMID: 12505971.
    Citations: 1     Fields:    Translation:Humans
  132. Rieder J, Lirk P. Neonatal atracurium toxicity may be explained by atracurium moieties. Paediatr Anaesth. 2002 Sep; 12(7):656-7. PMID: 12358671.
    Citations:    Fields:    Translation:HumansCells
  133. Gruber G, Lirk P, Amann A, Keller C, Schobersberger W, Hoffmann G, Fuchs D, Rieder J. Neopterin as a marker of immunostimulation: an investigation in anaesthetic workplaces. Anaesthesia. 2002 Aug; 57(8):747-50. PMID: 12133085.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  134. Rieder J, Keller C, Brimacombe J, Gruber G, Lirk P, Summer G, Amann A. Monitoring pollution by proton-transfer-reaction mass spectrometry during paediatric anaesthesia with positive pressure ventilation via the laryngeal mask airway or uncuffed tracheal tube. Anaesthesia. 2002 Jul; 57(7):663-6. PMID: 12059825.
    Citations: 1     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  135. Lirk P, Hoffmann G, Rieder J. Inducible nitric oxide synthase--time for reappraisal. Curr Drug Targets Inflamm Allergy. 2002 Mar; 1(1):89-108. PMID: 14561209.
    Citations: 36     Fields:    Translation:HumansAnimals
  136. Rieder J, Lirk P, Summer G, Gunkel A, Riccabona U, Innerhofer P, Amann A. Exposure to sevoflurane in otorhinolaryngologic operations. Can J Anaesth. 2001 Oct; 48(9):934. PMID: 11606358.
    Citations:    Fields:    Translation:HumansPHPublic Health
  137. Rieder J, Lirk P, Ebenbichler C, Gruber G, Prazeller P, Lindinger W, Amann A. Analysis of volatile organic compounds: possible applications in metabolic disorders and cancer screening. Wien Klin Wochenschr. 2001 Mar 15; 113(5-6):181-5. PMID: 11293947.
    Citations: 8     Fields:    Translation:Humans
  138. Rieder J, Prazeller P, Boehler M, Lirk P, Lindinger W, Amann A. Online monitoring of air quality at the postanesthetic care unit by proton-transfer-reaction mass spectrometry. Anesth Analg. 2001 Feb; 92(2):389-92. PMID: 11159238.
    Citations: 5     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.