Harvard Catalyst Profiles

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Jana Ellegast, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Cremer A, Ellegast JM, Alexe G, Frank ES, Ross L, Chu SH, Pikman Y, Robichaud A, Goodale A, Häupl B, Mohr S, Rao AV, Walker AR, Blachly JS, Piccioni F, Armstrong SA, Byrd JC, Oellerich T, Stegmaier K. Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia. Cancer Discov. 2020 02; 10(2):214-231. PMID: 31771968.
    Citations: 1     Fields:    
  2. Rudat S, Pfaus A, Cheng YY, Holtmann J, Ellegast JM, Bühler C, Marcantonio DD, Martinez E, Göllner S, Wickenhauser C, Müller-Tidow C, Lutz C, Bullinger L, Milsom MD, Sykes SM, Fröhling S, Scholl C. RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia. Leukemia. 2018 10; 32(10):2189-2202. PMID: 29654265.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  3. LaRochelle JR, Fodor M, Ellegast JM, Liu X, Vemulapalli V, Mohseni M, Stams T, Buhrlage SJ, Stegmaier K, LaMarche MJ, Acker MG, Blacklow SC. Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2. Bioorg Med Chem. 2017 12 15; 25(24):6479-6485. PMID: 29089257.
    Citations: 1     Fields:    Translation:HumansCells
  4. Ellegast JM, Rauch PJ, Kovtonyuk LV, Müller R, Wagner U, Saito Y, Wildner-Verhey van Wijk N, Fritz C, Rafiei A, Lysenko V, Dudkiewicz E, Theocharides AP, Soldini D, Goede JS, Flavell RA, Manz MG. inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice. Blood. 2016 10 27; 128(17):2130-2134. PMID: 27581357.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  5. Rauch PJ, Ellegast JM, Widmer CC, Fritsch K, Goede JS, Valk PJ, Löwenberg B, Takizawa H, Manz MG. MPL expression on AML blasts predicts peripheral blood neutropenia and thrombocytopenia. Blood. 2016 11 03; 128(18):2253-2257. PMID: 27574191.
    Citations: 9     Fields:    Translation:HumansCells
  6. Saito Y, Ellegast JM, Rafiei A, Song Y, Kull D, Heikenwalder M, Rongvaux A, Halene S, Flavell RA, Manz MG. Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice. Blood. 2016 10 06; 128(14):1829-1833. PMID: 27543436.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  7. Saito Y, Ellegast JM, Manz MG. Generation of Humanized Mice for Analysis of Human Dendritic Cells. Methods Mol Biol. 2016; 1423:309-20. PMID: 27142026.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  8. Azoitei N, Hoffmann CM, Ellegast JM, Ball CR, Obermayer K, Gößele U, Koch B, Faber K, Genze F, Schrader M, Kestler HA, Döhner H, Chiosis G, Glimm H, Fröhling S, Scholl C. Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33. J Exp Med. 2012 Apr 09; 209(4):697-711. PMID: 22451720.
    Citations: 26     Fields:    Translation:HumansCells
  9. Ellegast J, Barth TF, Schulte M, Bielack SS, Schmid M, Mayer-Steinacker R. Metastasis of osteosarcoma after 16 years. J Clin Oncol. 2011 Jan 20; 29(3):e62-6. PMID: 21041714.
    Citations: 2     Fields:    Translation:Humans
  10. Hornung V, Ellegast J, Kim S, Brzózka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G. 5'-Triphosphate RNA is the ligand for RIG-I. Science. 2006 Nov 10; 314(5801):994-7. PMID: 17038590.
    Citations: 807     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.