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Leilah K. Grant, Ph.D.

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Biography
Monash University, AustraliaBSc (Hons)10/2013Psychology
Monash University, AustraliaPhD07/2018Psychological Medicine
2017
Abstract Excellence Award - Australasian Chronobiology Society
2019
Certificate of Distinction in Teaching - Derek Bok Center, Harvard University
2020
Abstract Merit Award - Society for Research on Biological Rhythms
2020
Research Excellence Award - Brigham Research Institute
2021
Outstanding Abstract Award - Endocrine Society
2022 - 2023
Mary Ann Tynan Research Scientist - Connors Center for Women's Health and Gender Biology, BWH

Overview
Dr. Grant is an Investigator (Associate Physiologist) in the Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, and an Instructor in Medicine, Harvard Medical School. Her research focuses on the effects of sleep, the circadian system and light on behavioral, metabolic, and endocrine outcomes in humans.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. (Grant, Leilah K) Aug 1, 2022 - Jul 31, 2023
    Pollin Research Award for Innovation in Women’s Cardiovascular Health
    Time-restricted eating as a dietary intervention for dyslipidemia in postmenopausal women
    Role Description: The goal of this project is to examine the effect of an 8-hour time-restricted eating intervention on circulating lipids and visceral adiposity in recently postmenopausal women with untreated dyslipidemia.
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Rahman SA, Kent BA, Grant LK, Clark T, Hanifin JP, Barger LK, Czeisler CA, Brainard GC, St Hilaire MA, Lockley SW. Effects of dynamic lighting on circadian phase, self-reported sleep and performance during a 45-day space analog mission with chronic variable sleep deficiency. J Pineal Res. 2022 Nov; 73(4):e12826. PMID: 35996978.
    Citations:    Fields:    Translation:Humans
  2. Grant LK, St Hilaire MA, Heller JP, Heller RA, Lockley SW, Rahman SA. Impact of Upgraded Lighting on Falls in Care Home Residents. J Am Med Dir Assoc. 2022 10; 23(10):1698-1704.e2. PMID: 35850166.
    Citations:    Fields:    
  3. Grant LK, Coborn JE, Cohn A, Nathan MD, Scheer FAJL, Klerman EB, Kaiser UB, Harder J, Abramson M, Elguenaoui E, Russell JA, Wiley A, Rahman SA, Joffe H. Sleep Fragmentation and Estradiol Suppression Decrease Fat Oxidation in Premenopausal Women. J Clin Endocrinol Metab. 2022 07 14; 107(8):e3167-e3176. PMID: 35569055; PMCID: PMC9282266.
    Citations: 1     Fields:    Translation:HumansCells
  4. Rahman SA, St Hilaire MA, Grant LK, Barger LK, Brainard GC, Czeisler CA, Klerman EB, Lockley SW. Dynamic lighting schedules to facilitate circadian adaptation to shifted timing of sleep and wake. J Pineal Res. 2022 Aug; 73(1):e12805. PMID: 35501292.
    Citations:    Fields:    Translation:Humans
  5. Rahman SA, Nathan MD, Wiley A, Crawford S, Cohn AY, Harder JA, Grant LK, Erickson A, Srivastava A, McCormick K, Bertisch SM, Winkelman JW, Joffe H. A double-blind, randomized, placebo-controlled trial of suvorexant for the treatment of vasomotor symptom-associated insomnia disorder in midlife women. Sleep. 2022 03 14; 45(3). PMID: 35022783.
    Citations:    Fields:    Translation:Humans
  6. Kent BA, Rahman SA, St Hilaire MA, Grant LK, Rüger M, Czeisler CA, Lockley SW. Circadian lipid and hepatic protein rhythms shift with a phase response curve different than melatonin. Nat Commun. 2022 02 03; 13(1):681. PMID: 35115537; PMCID: PMC8814172.
    Citations: 1     Fields:    Translation:Humans
  7. Grant LK, St Hilaire MA, Brainard GC, Czeisler CA, Lockley SW, Rahman SA. Endogenous circadian regulation and phase resetting of clinical metabolic biomarkers. J Pineal Res. 2021 Sep; 71(2):e12752. PMID: 34118084.
    Citations: 2     Fields:    Translation:Humans
  8. Grant LK, Czeisler CA, Lockley SW, Rahman SA. Time-of-day and Meal Size Effects on Clinical Lipid Markers. J Clin Endocrinol Metab. 2021 Mar 08; 106(3):e1373-e1379. PMID: 34932808.
    Citations:    Fields:    
  9. Grant LK, Kent BA, Mayer MD, Stickgold R, Lockley SW, Rahman SA. Daytime Exposure to Short Wavelength-Enriched Light Improves Cognitive Performance in Sleep-Restricted College-Aged Adults. Front Neurol. 2021; 12:624217. PMID: 33692742.
    Citations: 4     
  10. Grant LK, Gooley JJ, St Hilaire MA, Rajaratnam SMW, Brainard GC, Czeisler CA, Lockley SW, Rahman SA. Menstrual phase-dependent differences in neurobehavioral performance: the role of temperature and the progesterone/estradiol ratio. Sleep. 2020 02 13; 43(2). PMID: 31670824.
    Citations: 2     Fields:    Translation:Humans
  11. Rahman SA, Grant LK, Gooley JJ, Rajaratnam SMW, Czeisler CA, Lockley SW. Endogenous Circadian Regulation of Female Reproductive Hormones. J Clin Endocrinol Metab. 2019 12 01; 104(12):6049-6059. PMID: 31415086; PMCID: PMC6821202.
    Citations: 15     Fields:    Translation:Humans
  12. Grant LK, Ftouni S, Nijagal B, De Souza DP, Tull D, McConville MJ, Rajaratnam SMW, Lockley SW, Anderson C. Circadian and wake-dependent changes in human plasma polar metabolites during prolonged wakefulness: A preliminary analysis. Sci Rep. 2019 03 14; 9(1):4428. PMID: 30872634.
    Citations: 14     Fields:    Translation:Humans
  13. Grant LK, Cain SW, Chang AM, Saxena R, Czeisler CA, Anderson C. Impaired cognitive flexibility during sleep deprivation among carriers of the Brain Derived Neurotrophic Factor (BDNF) Val66Met allele. Behav Brain Res. 2018 02 15; 338:51-55. PMID: 28947280; PMCID: PMC5957758.
    Citations: 7     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.