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Ioannis Vlachos, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Eismann J, Heng YJ, Waldschmidt JM, Vlachos IS, Gray KP, Matulonis UA, Konstantinopoulos PA, Murphy CJ, Nabavi S, Wulf GM. Transcriptome analysis reveals overlap in fusion genes in a phase I clinical cohort of TNBC and HGSOC patients treated with buparlisib and olaparib. J Cancer Res Clin Oncol. 2020 Feb; 146(2):503-514. PMID: 31745703.
  2. Kaminiotis VV, Agrogiannis G, Konstantopoulos P, Androutsopoulou V, Korou LM, Vlachos IS, Dontas IA, Perrea D, Iliopoulos DC. Per os colchicine administration in cholesterol fed rabbits: Triglycerides lowering effects without affecting atherosclerosis progress. Lipids Health Dis. 2017 Sep 26; 16(1):184. PMID: 28950870.
    Citations:    Fields:    Translation:Animals
  3. Zagganas K, Vergoulis T, Paraskevopoulou MD, Vlachos IS, Skiadopoulos S, Dalamagas T. BUFET: boosting the unbiased miRNA functional enrichment analysis using bitsets. BMC Bioinformatics. 2017 Sep 06; 18(1):399. PMID: 28874117.
    Citations:    Fields:    
  4. Kouroupi G, Taoufik E, Vlachos IS, Tsioras K, Antoniou N, Papastefanaki F, Chroni-Tzartou D, Wrasidlo W, Bohl D, Stellas D, Politis PK, Vekrellis K, Papadimitriou D, Stefanis L, Bregestovski P, Hatzigeorgiou AG, Masliah E, Matsas R. Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):E3679-E3688. PMID: 28416701.
    Citations: 7     Fields:    Translation:HumansCells
  5. Fragkouli A, Koukouraki P, Vlachos IS, Paraskevopoulou MD, Hatzigeorgiou AG, Doxakis E. Neuronal ELAVL proteins utilize AUF-1 as a co-partner to induce neuron-specific alternative splicing of APP. Sci Rep. 2017 03 14; 7:44507. PMID: 28291226.
    Citations: 2     Fields:    Translation:HumansCells
  6. Kotoula V, Fostira F, Papadopoulou K, Apostolou P, Tsolaki E, Lazaridis G, Manoussou K, Zagouri F, Pectasides D, Vlachos I, Tikas I, Lakis S, Konstantopoulou I, Pentheroudakis G, Gogas H, Papakostas P, Christodoulou C, Bafaloukos D, Razis E, Karavasilis V, Bamias C, Yannoukakos D, Fountzilas G. The fate of BRCA1-related germline mutations in triple-negative breast tumors. Am J Cancer Res. 2017; 7(1):98-114. PMID: 28123851.
  7. Vlachos IS, Hatzigeorgiou AG. Functional Analysis of miRNAs Using the DIANA Tools Online Suite. Methods Mol Biol. 2017; 1517:25-50. PMID: 27924472.
    Citations: 3     Fields:    Translation:HumansCells
  8. Papanicolaou A, Schetelig MF, Arensburger P, Atkinson PW, Benoit JB, Bourtzis K, Castañera P, Cavanaugh JP, Chao H, Childers C, Curril I, Dinh H, Doddapaneni H, Dolan A, Dugan S, Friedrich M, Gasperi G, Geib S, Georgakilas G, Gibbs RA, Giers SD, Gomulski LM, González-Guzmán M, Guillem-Amat A, Han Y, Hatzigeorgiou AG, Hernández-Crespo P, Hughes DS, Jones JW, Karagkouni D, Koskinioti P, Lee SL, Malacrida AR, Manni M, Mathiopoulos K, Meccariello A, Murali SC, Murphy TD, Muzny DM, Oberhofer G, Ortego F, Paraskevopoulou MD, Poelchau M, Qu J, Reczko M, Robertson HM, Rosendale AJ, Rosselot AE, Saccone G, Salvemini M, Savini G, Schreiner P, Scolari F, Siciliano P, Sim SB, Tsiamis G, Ureña E, Vlachos IS, Werren JH, Wimmer EA, Worley KC, Zacharopoulou A, Richards S, Handler AM. The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species. Genome Biol. 2016 09 22; 17(1):192. PMID: 27659211.
    Citations: 12     Fields:    Translation:HumansAnimalsPHPublic Health
  9. Paraskevopoulou MD, Vlachos IS, Hatzigeorgiou AG. DIANA-TarBase and DIANA Suite Tools: Studying Experimentally Supported microRNA Targets. Curr Protoc Bioinformatics. 2016 09 07; 55:12.14.1-12.14.18. PMID: 27603020.
    Citations: 4     Fields:    Translation:Animals
  10. Vlachos IS, Vergoulis T, Paraskevopoulou MD, Lykokanellos F, Georgakilas G, Georgiou P, Chatzopoulos S, Karagkouni D, Christodoulou F, Dalamagas T, Hatzigeorgiou AG. DIANA-mirExTra v2.0: Uncovering microRNAs and transcription factors with crucial roles in NGS expression data. Nucleic Acids Res. 2016 07 08; 44(W1):W128-34. PMID: 27207881.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  11. Paraskevopoulou MD, Vlachos IS, Karagkouni D, Georgakilas G, Kanellos I, Vergoulis T, Zagganas K, Tsanakas P, Floros E, Dalamagas T, Hatzigeorgiou AG. DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts. Nucleic Acids Res. 2016 Jan 04; 44(D1):D231-8. PMID: 26612864.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  12. Georgakilas G, Vlachos IS, Zagganas K, Vergoulis T, Paraskevopoulou MD, Kanellos I, Tsanakas P, Dellis D, Fevgas A, Dalamagas T, Hatzigeorgiou AG. DIANA-miRGen v3.0: accurate characterization of microRNA promoters and their regulators. Nucleic Acids Res. 2016 Jan 04; 44(D1):D190-5. PMID: 26586797.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  13. Triantafyllidou O, Vlachos IS, Apostolou P, Konstantopoulou I, Grivas A, Panopoulos C, Dimitrakakis C, Kassanos D, Loghis C, Bramis I, Vlahos N, Yannoukakos D, Fostira F. Epidemiological and clinicopathological characteristics of BRCA-positive and BRCA-negative breast cancer patients in Greece. J BUON. 2015 Jul-Aug; 20(4):978-84. PMID: 26416046.
    Citations:    Fields:    Translation:Humans
  14. Vlachos IS, Zagganas K, Paraskevopoulou MD, Georgakilas G, Karagkouni D, Vergoulis T, Dalamagas T, Hatzigeorgiou AG. DIANA-miRPath v3.0: deciphering microRNA function with experimental support. Nucleic Acids Res. 2015 Jul 01; 43(W1):W460-6. PMID: 25977294.
    Citations: 180     Fields:    Translation:HumansAnimals
  15. Georgakilas G, Vlachos IS, Paraskevopoulou MD, Yang P, Zhang Y, Economides AN, Hatzigeorgiou AG. microTSS: accurate microRNA transcription start site identification reveals a significant number of divergent pri-miRNAs. Nat Commun. 2014 Dec 10; 5:5700. PMID: 25492647.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  16. Vlachos IS, Paraskevopoulou MD, Karagkouni D, Georgakilas G, Vergoulis T, Kanellos I, Anastasopoulos IL, Maniou S, Karathanou K, Kalfakakou D, Fevgas A, Dalamagas T, Hatzigeorgiou AG. DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions. Nucleic Acids Res. 2015 Jan; 43(Database issue):D153-9. PMID: 25416803.
    Citations: 177     Fields:    Translation:Cells
  17. Korou LM, Agrogiannis G, Koros C, Kitraki E, Vlachos IS, Tzanetakou I, Karatzas T, Pergialiotis V, Dimitroulis D, Perrea DN. Impact of N-acetylcysteine and sesame oil on lipid metabolism and hypothalamic-pituitary-adrenal axis homeostasis in middle-aged hypercholesterolemic mice. Sci Rep. 2014 Oct 28; 4:6806. PMID: 25348324.
    Citations: 5     Fields:    Translation:Animals
  18. Moschonas DP, Piperi C, Korkolopoulou P, Levidou G, Kavantzas N, Trigka EA, Vlachos I, Arapostathi C, Perrea D, Mitropoulos D, Diamanti-Kandarakis E, Papavassiliou AG. Impact of diet-induced obesity in male mouse reproductive system: The role of advanced glycation end product-receptor for advanced glycation end product axis. Exp Biol Med (Maywood). 2014 08; 239(8):937-947. PMID: 24872429.
    Citations:    Fields:    
  19. Stathaki M, Armakolas A, Dimakakos A, Kaklamanis L, Vlachos I, Konstantoulakis MM, Zografos G, Koutsilieris M. Kisspeptin effect on endothelial monocyte activating polypeptide II (EMAP-II)-associated lymphocyte cell death and metastases in colorectal cancer patients. Mol Med. 2014 Mar 18; 20:80-92. PMID: 24395571.
    Citations: 2     Fields:    Translation:HumansCells
  20. Georgiadis I, Karatzas T, Korou LM, Agrogiannis G, Vlachos IS, Pantopoulou A, Tzanetakou IP, Katsilambros N, Perrea DN. Evaluation of Chios mastic gum on lipid and glucose metabolism in diabetic mice. J Med Food. 2014 Mar; 17(3):393-9. PMID: 24404977.
    Citations:    Fields:    Translation:HumansAnimals
  21. Perrea A, Vlachos IS, Korou LM, Doulamis IP, Exarhopoulou K, Kypraios G, Kalofoutis A, Perrea DN. Comparison of the short-term oxidative stress response in National League basketball and soccer adolescent athletes. Angiology. 2014 Aug; 65(7):624-9. PMID: 23921505.
    Citations: 1     Fields:    Translation:HumansCells
  22. Paraskevopoulou MD, Vlachos IS, Athanasiadis E, Spyrou G. BiDaS: a web-based Monte Carlo BioData Simulator based on sequence/feature characteristics. Nucleic Acids Res. 2013 Jul; 41(Web Server issue):W582-6. PMID: 23716644.
    Citations:    Fields:    Translation:Cells
  23. Paraskevopoulou MD, Georgakilas G, Kostoulas N, Vlachos IS, Vergoulis T, Reczko M, Filippidis C, Dalamagas T, Hatzigeorgiou AG. DIANA-microT web server v5.0: service integration into miRNA functional analysis workflows. Nucleic Acids Res. 2013 Jul; 41(Web Server issue):W169-73. PMID: 23680784.
    Citations: 186     Fields:    Translation:HumansAnimals
  24. Vlachos IS, Hatzigeorgiou AG. Online resources for miRNA analysis. Clin Biochem. 2013 Jul; 46(10-11):879-900. PMID: 23518312.
    Citations: 19     Fields:    Translation:HumansAnimals
  25. Paschou M, Paraskevopoulou MD, Vlachos IS, Koukouraki P, Hatzigeorgiou AG, Doxakis E. miRNA regulons associated with synaptic function. PLoS One. 2012; 7(10):e46189. PMID: 23071543.
    Citations: 17     Fields:    Translation:HumansCells
  26. Perelas A, Safarika V, Vlachos IS, Tzanetakou I, Korou LM, Konstantopoulos P, Doulamis I, Ioannidis I, Kornezos I, Gargas D, Klonaris C, Perrea DN, Chatziioannou A. Correlation between mesenteric fat thickness and serum apolipoproteins in patients with peripheral arterial occlusive disease. Lipids Health Dis. 2012 Oct 01; 11:125. PMID: 23025515.
    Citations: 2     Fields:    Translation:Humans
  27. Kostakis ID, Cholidou KG, Vaiopoulos AG, Vlachos IS, Perrea D, Vaos G. Fecal calprotectin in pediatric inflammatory bowel disease: a systematic review. Dig Dis Sci. 2013 Feb; 58(2):309-19. PMID: 22899243.
    Citations: 11     Fields:    Translation:Humans
  28. Tzanetakou IP, Doulamis IP, Korou LM, Agrogiannis G, Vlachos IS, Pantopoulou A, Mikhailidis DP, Patsouris E, Vlachos I, Perrea DN. Water Soluble Vitamin E Administration in Wistar Rats with Non-alcoholic Fatty Liver Disease. Open Cardiovasc Med J. 2012; 6:88-97. PMID: 22930662.
    Citations: 2     
  29. Vlachos IS, Kostoulas N, Vergoulis T, Georgakilas G, Reczko M, Maragkakis M, Paraskevopoulou MD, Prionidis K, Dalamagas T, Hatzigeorgiou AG. DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic Acids Res. 2012 Jul; 40(Web Server issue):W498-504. PMID: 22649059.
    Citations: 216     Fields:    Translation:Humans
  30. Fotis L, Agrogiannis G, Vlachos IS, Pantopoulou A, Margoni A, Kostaki M, Verikokos C, Tzivras D, Mikhailidis DP, Perrea D. Intercellular adhesion molecule (ICAM)-1 and vascular cell adhesion molecule (VCAM)-1 at the early stages of atherosclerosis in a rat model. In Vivo. 2012 Mar-Apr; 26(2):243-50. PMID: 22351665.
    Citations: 24     Fields:    Translation:AnimalsCells
  31. Xanthos T, Karatzas T, Stroumpoulis K, Lelovas P, Simitsis P, Vlachos I, Kouraklis G, Kouskouni E, Dontas I. Continuous chest compressions improve survival and neurologic outcome in a swine model of prolonged ventricular fibrillation. Am J Emerg Med. 2012 Oct; 30(8):1389-94. PMID: 22205006.
    Citations: 6     Fields:    Translation:Animals
  32. Vergoulis T, Vlachos IS, Alexiou P, Georgakilas G, Maragkakis M, Reczko M, Gerangelos S, Koziris N, Dalamagas T, Hatzigeorgiou AG. TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support. Nucleic Acids Res. 2012 Jan; 40(Database issue):D222-9. PMID: 22135297.
    Citations: 238     Fields:    Translation:Humans
  33. Xanthos T, Bassiakou E, Koudouna E, Stroumpoulis K, Vlachos I, Johnson EO, Vasileiou P, Papalois A, Iacovidou N. Inexperienced nurses and doctors are equally efficient in managing the airway in a manikin model. Heart Lung. 2012 Mar-Apr; 41(2):161-6. PMID: 21893345.
    Citations: 1     Fields:    Translation:Humans
  34. Margaritis EV, Yanni AE, Agrogiannis G, Liarakos N, Pantopoulou A, Vlachos I, Papachristodoulou A, Korkolopoulou P, Patsouris E, Kostakis M, Perrea DN, Kostakis A. Effects of oral administration of (L)-arginine, (L)-NAME and allopurinol on intestinal ischemia/reperfusion injury in rats. Life Sci. 2011 Jun 06; 88(23-24):1070-6. PMID: 21565201.
    Citations: 5     Fields:    Translation:Animals
  35. Arapostathi C, Tzanetakou IP, Kokkinos AD, Tentolouris NK, Vlachos IS, Donta IA, Perrea KN, Perrea DN, Katsilambros NL. A diet rich in monounsaturated fatty acids improves the lipid profile of mice previously on a diet rich in saturated fatty acids. Angiology. 2011 Nov; 62(8):636-40. PMID: 21511678.
    Citations: 1     Fields:    Translation:Animals
  36. Paraskevas KI, Pantopoulou A, Vlachos IS, Agrogiannis G, Iliopoulos DG, Karatzas G, Tzivras D, Mikhailidis DP, Perrea DN. Comparison of fibrate, ezetimibe, low- and high-dose statin therapy for the dyslipidemia of the metabolic syndrome in a mouse model. Angiology. 2011 Feb; 62(2):144-54. PMID: 21220373.
    Citations: 3     Fields:    Translation:Animals
  37. Bellos JK, Perrea DN, Theodoropoulou E, Vlachos I, Papachristodoulou A, Kostakis AI. Clinical correlation of nitric oxide levels with acute rejection in renal transplantation. Int Urol Nephrol. 2011 Sep; 43(3):883-90. PMID: 20957433.
    Citations: 1     Fields:    Translation:Humans
  38. Margoni A, Perrea DN, Vlachos I, Prokopaki G, Pantopoulou A, Fotis L, Kostaki M, Papavassiliou AG. Serum leptin, adiponectin and tumor necrosis factor-a in hyperlipidemic rats with/without concomitant diabetes mellitus. Mol Med. 2011 Jan-Feb; 17(1-2):36-40. PMID: 20838752.
    Citations: 8     Fields:    Translation:Animals
  39. Xanthos T, Pantazopoulos I, Vlachos I, Stroumpoulis K, Barouxis D, Kitsou V, Marathias K, Karabinis A, Papadimitriou L. Factors influencing arrival of patients with acute myocardial infarction at emergency departments: implications for community nursing interventions. J Adv Nurs. 2010 Jul; 66(7):1469-77. PMID: 20492020.
    Citations:    Fields:    Translation:Humans
  40. Korou LM, Agrogiannis G, Pantopoulou A, Vlachos IS, Iliopoulos D, Karatzas T, Perrea DN. Comparative antilipidemic effect of N-acetylcysteine and sesame oil administration in diet-induced hypercholesterolemic mice. Lipids Health Dis. 2010 Mar 06; 9:23. PMID: 20205925.
    Citations: 7     Fields:    Translation:AnimalsCells
  41. Xanthos T, Iacovidou N, Pantazopoulos I, Vlachos I, Bassiakou E, Stroumpoulis K, Kouskouni E, Karabinis A, Papadimitriou L. Ischaemia-modified albumin predicts the outcome of cardiopulmonary resuscitation: An experimental study. Resuscitation. 2010 May; 81(5):591-5. PMID: 20189703.
    Citations:    Fields:    Translation:Animals
  42. Tsitsilonis S, Vlachos IS, Bampali A, Revenas K, Votteas V, Perrea DN. Sonographic measurements of subcutaneous fat in obese individuals may correlate better with peripheral artery disease indices. J Clin Ultrasound. 2009 Jun; 37(5):263-9. PMID: 19353552.
    Citations: 1     Fields:    Translation:Humans
  43. Doumouchtsis K, Perrea D, Doumouchtsis S, Tziamalis M, Poulakou M, Vlachos I, Kostakis A. Regulatory effect of parathyroid hormone on sRANKL-osteoprotegerin in hemodialysis patients with renal bone disease. Ther Apher Dial. 2009 Feb; 13(1):49-55. PMID: 19379170.
    Citations: 4     Fields:    Translation:Humans
  44. Perrea DN, Ekmektzoglou KA, Vlachos IS, Tsitsilonis S, Koudouna E, Stroumpoulis K, Xanthos T. A formula for the stratified selection of patients with paroxysmal atrial fibrillation in the emergency setting: a retrospective pilot study. J Emerg Med. 2011 Apr; 40(4):374-9. PMID: 18829204.
    Citations: 2     Fields:    Translation:Humans
  45. Moulakakis KG, Poulakou MV, Dosios T, Dontas I, Sokolis DP, Vlachos IS, Safioleas MC, Papachristodoulou A, Karayannacos PE, Perrea DN. Hypothyroidism and the aorta. evidence of increased oxidative DNA damage to the aorta of hypothyroid rats. In Vivo. 2008 Sep-Oct; 22(5):603-8. PMID: 18853754.
    Citations: 3     Fields:    Translation:AnimalsCells
  46. Xanthos T, Ekmektzoglou KA, Vlachos IS, Dimitroulis D, Tsitsilonis S, Karatzas T, Perrea DN. A prognostic index for the successful use of adenosine in patients with paroxysmal supraventricular tachycardia in emergency settings: a retrospective study. Am J Emerg Med. 2008 Mar; 26(3):304-9. PMID: 18358941.
    Citations: 1     Fields:    Translation:Humans
  47. Kantsos H, Papadopoulos S, Perrea D, Xanthos T, Vlachos I, Pantopoulou A, Agrogiannis G, Condilis N, Lazaris A, Patsouris E, Bramis J. Effects of nimodipine administration on small bowel mucosa under conditions of laparotomy and consequent 48-hour starvation in a rat model. Ann Ital Chir. 2008 Mar-Apr; 79(2):143-9. PMID: 18727279.
    Citations:    Fields:    Translation:AnimalsCells
  48. Perrea DN, Moulakakis KG, Poulakou MV, Vlachos IS, Nikiteas N, Kostakis A. Correlation between lipid abnormalities and immunosuppressive therapy in renal transplant recipients with stable renal function. Int Urol Nephrol. 2008; 40(2):521-7. PMID: 17978855.
    Citations: 2     Fields:    Translation:Humans
  49. Doumouchtsis KK, Kostakis AI, Doumouchtsis SK, Grapsa EI, Passalidou IA, Tziamalis MP, Poulakou MV, Vlachos IS, Perrea DN. The effect of sexual hormone abnormalities on proximal femur bone mineral density in hemodialysis patients and the possible role of RANKL. Hemodial Int. 2008 Jan; 12(1):100-7. PMID: 18271850.
    Citations: 6     Fields:    Translation:Humans
  50. Vlachos IS, Hatziioannou A, Perelas A, Perrea DN. Sonographic assessment of regional adiposity. AJR Am J Roentgenol. 2007 Dec; 189(6):1545-53. PMID: 18029899.
    Citations: 16     Fields:    Translation:Humans
  51. Moulakakis KG, Poulakou MV, Paraskevas KI, Dontas I, Vlachos IS, Sokolis DP, Dosios T, Karayannacos PE, Perrea D. Hyperthyroidism is associated with increased aortic oxidative DNA damage in a rat model. In Vivo. 2007 Nov-Dec; 21(6):1021-6. PMID: 18210749.
    Citations: 2     Fields:    Translation:AnimalsCells
  52. Xanthos T, Bassiakou E, Vlachos IS, Bassiakos S, Michalakis K, Moutzouris DA, Papadimitriou L. Intravenous and oral administration of amiodarone for the treatment of recent onset atrial fibrillation after digoxin administration. Int J Cardiol. 2007 Oct 18; 121(3):291-5. PMID: 17434635.
    Citations: 1     Fields:    Translation:Humans
  53. Xanthos T, Tsirikos-Karapanos N, Papadimitriou D, Vlachos IS, Tsiftsi K, Ekmektzoglou KA, Papadimitriou L. Resuscitation outcomes comparing year 2000 with year 2005 ALS guidelines in a pig model of cardiac arrest. Resuscitation. 2007 Jun; 73(3):459-66. PMID: 17291669.
    Citations:    Fields:    Translation:Animals
  54. Perrea DN, Moulakakis KG, Poulakou MV, Vlachos IS, Papachristodoulou A, Kostakis AI. Correlation between oxidative stress and immunosuppressive therapy in renal transplant recipients with an uneventful postoperative course and stable renal function. Int Urol Nephrol. 2006; 38(2):343-8. PMID: 16868708.
    Citations: 8     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.