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Philip Hanna, Mb.Bch,Bao

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Williamson PM, Pennings JP, Harlow E, Hanna P, Lechtig A, Okajima S, Biggane P, Nasr M, Zurakowski D, Duggal N, Nazarian A. Tendon lengthening after achilles tendon rupture-passive effects on the ankle joint in a cadaveric pilot study simulating weight bearing. Injury. 2020 Feb; 51(2):532-536. PMID: 31685206.
    Citations:    
  2. Hanna PC. Mining iron: anthrax and heme. Mol Microbiol. 2019 12; 112(6):1632-1634. PMID: 31397001.
    Citations:    
  3. Mortensen SJ, Vora MM, Mohamadi A, Wright CL, Hanna P, Lechtig A, Egan J, Williamson PM, Wixted JJ, Rutkove SB, Nazarian A. Diagnostic Modalities for Acute Compartment Syndrome of the Extremities: A Systematic Review. JAMA Surg. 2019 Jul 01; 154(7):655-665. PMID: 31042278.
    Citations:    
  4. Hagan AK, Plotnick YM, Dingle RE, Mendel ZI, Cendrowski SR, Sherman DH, Tripathi A, Hanna PC. Petrobactin Protects against Oxidative Stress and Enhances Sporulation Efficiency in Bacillus anthracis Sterne. mBio. 2018 11 06; 9(6). PMID: 30401780.
    Citations:    Fields:    
  5. Okajima SM, Cubria MB, Mortensen SJ, Villa-Camacho JC, Hanna P, Lechtig A, Perez-Viloria M, Williamson P, Grinstaff MW, Rodriguez EK, Nazarian A. Rat Model of Adhesive Capsulitis of the Shoulder. J Vis Exp. 2018 09 28; (139). PMID: 30320752.
    Citations:    Fields:    
  6. Kochan TJ, Shoshiev MS, Hastie JL, Somers MJ, Plotnick YM, Gutierrez-Munoz DF, Foss ED, Schubert AM, Smith AD, Zimmerman SK, Carlson PE, Hanna PC. Germinant Synergy Facilitates Clostridium difficile Spore Germination under Physiological Conditions. mSphere. 2018 09 05; 3(5). PMID: 30185513.
    Citations:    Translation:AnimalsCells
  7. Kochan TJ, Foley MH, Shoshiev MS, Somers MJ, Carlson PE, Hanna PC. Updates to Clostridium difficile Spore Germination. J Bacteriol. 2018 08 15; 200(16). PMID: 29760211.
    Citations:    Fields:    
  8. Williamson P, Lechtig A, Hanna P, Okajima S, Biggane P, Nasr M, Zurakowski D, Duggal N, Nazarian A. Pressure Distribution in the Ankle and Subtalar Joint With Routine and Oversized Foot Orthoses. Foot Ankle Int. 2018 08; 39(8):994-1000. PMID: 29696991.
    Citations:    Fields:    
  9. Hagan AK, Tripathi A, Berger D, Sherman DH, Hanna PC. Erratum for Hagan et al., "Petrobactin Is Exported from Bacillus anthracis by the RND-Type Exporter ApeX". mBio. 2017 10 17; 8(5). PMID: 29042503.
    Citations:    
  10. Hagan AK, Tripathi A, Berger D, Sherman DH, Hanna PC. Petrobactin Is Exported from Bacillus anthracis by the RND-Type Exporter ApeX. mBio. 2017 09 12; 8(5). PMID: 28900020.
    Citations:    
  11. Kochan TJ, Somers MJ, Kaiser AM, Shoshiev MS, Hagan AK, Hastie JL, Giordano NP, Smith AD, Schubert AM, Carlson PE, Hanna PC. Intestinal calcium and bile salts facilitate germination of Clostridium difficile spores. PLoS Pathog. 2017 Jul; 13(7):e1006443. PMID: 28704538.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  12. McGarry A, McDermott M, Kieburtz K, de Blieck EA, Beal F, Marder K, Ross C, Shoulson I, Gilbert P, Mallonee WM, Guttman M, Wojcieszek J, Kumar R, LeDoux MS, Jenkins M, Rosas HD, Nance M, Biglan K, Como P, Dubinsky RM, Shannon KM, O'Suilleabhain P, Chou K, Walker F, Martin W, Wheelock VL, McCusker E, Jankovic J, Singer C, Sanchez-Ramos J, Scott B, Suchowersky O, Factor SA, Higgins DS, Molho E, Revilla F, Caviness JN, Friedman JH, Perlmutter JS, Feigin A, Anderson K, Rodriguez R, McFarland NR, Margolis RL, Farbman ES, Raymond LA, Suski V, Kostyk S, Colcher A, Seeberger L, Epping E, Esmail S, Diaz N, Fung WL, Diamond A, Frank S, Hanna P, Hermanowicz N, Dure LS, Cudkowicz M. A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease. Neurology. 2017 Jan 10; 88(2):152-159. PMID: 27913695.
    Citations: 9     Fields:    Translation:Humans
  13. Hagan AK, Carlson PE, Hanna PC. Flying under the radar: The non-canonical biochemistry and molecular biology of petrobactin from Bacillus anthracis. Mol Microbiol. 2016 10; 102(2):196-206. PMID: 27425635.
    Citations:    
  14. Carlson PE, Bourgis AE, Hagan AK, Hanna PC. Global gene expression by Bacillus anthracis during growth in mammalian blood. Pathog Dis. 2015 Nov; 73(8):ftv061. PMID: 26316554.
    Citations: 2     Fields:    Translation:AnimalsCells
  15. Carlson PE, Kaiser AM, McColm SA, Bauer JM, Young VB, Aronoff DM, Hanna PC. Variation in germination of Clostridium difficile clinical isolates correlates to disease severity. Anaerobe. 2015 Jun; 33:64-70. PMID: 25681667.
    Citations: 12     Fields:    Translation:HumansCells
  16. Tripathi A, Schofield MM, Chlipala GE, Schultz PJ, Yim I, Newmister SA, Nusca TD, Scaglione JB, Hanna PC, Tamayo-Castillo G, Sherman DH. Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis. J Am Chem Soc. 2014 Jan 29; 136(4):1579-86. PMID: 24401083.
    Citations: 14     Fields:    Translation:Cells
  17. Carlson PE, Walk ST, Bourgis AE, Liu MW, Kopliku F, Lo E, Young VB, Aronoff DM, Hanna PC. The relationship between phenotype, ribotype, and clinical disease in human Clostridium difficile isolates. Anaerobe. 2013 Dec; 24:109-16. PMID: 23608205.
    Citations: 23     Fields:    Translation:HumansCells
  18. Dixon SD, Janes BK, Bourgis A, Carlson PE, Hanna PC. Multiple ABC transporters are involved in the acquisition of petrobactin in Bacillus anthracis. Mol Microbiol. 2012 Apr; 84(2):370-82. PMID: 22429808.
    Citations: 4     Fields:    Translation:AnimalsCells
  19. Nusca TD, Kim Y, Maltseva N, Lee JY, Eschenfeldt W, Stols L, Schofield MM, Scaglione JB, Dixon SD, Oves-Costales D, Challis GL, Hanna PC, Pfleger BF, Joachimiak A, Sherman DH. Functional and structural analysis of the siderophore synthetase AsbB through reconstitution of the petrobactin biosynthetic pathway from Bacillus anthracis. J Biol Chem. 2012 May 04; 287(19):16058-72. PMID: 22408253.
    Citations: 6     Fields:    Translation:Cells
  20. Wilson MJ, Carlson PE, Janes BK, Hanna PC. Membrane topology of the Bacillus anthracis GerH germinant receptor proteins. J Bacteriol. 2012 Mar; 194(6):1369-77. PMID: 22178966.
    Citations: 7     Fields:    Translation:Cells
  21. Lee JY, Passalacqua KD, Hanna PC, Sherman DH. Regulation of petrobactin and bacillibactin biosynthesis in Bacillus anthracis under iron and oxygen variation. PLoS One. 2011; 6(6):e20777. PMID: 21673962.
    Citations: 12     Fields:    Translation:Cells
  22. Carr KA, Janes BK, Hanna PC. Role of the gerP operon in germination and outgrowth of Bacillus anthracis spores. PLoS One. 2010 Feb 09; 5(2):e9128. PMID: 20161744.
    Citations: 9     Fields:    Translation:Cells
  23. Carlson PE, Dixon SD, Janes BK, Carr KA, Nusca TD, Anderson EC, Keene SE, Sherman DH, Hanna PC. Genetic analysis of petrobactin transport in Bacillus anthracis. Mol Microbiol. 2010 Feb; 75(4):900-9. PMID: 20487286.
    Citations: 5     Fields:    Translation:AnimalsCells
  24. Carr KA, Lybarger SR, Anderson EC, Janes BK, Hanna PC. The role of Bacillus anthracis germinant receptors in germination and virulence. Mol Microbiol. 2010 Jan; 75(2):365-75. PMID: 19943909.
    Citations: 11     Fields:    Translation:Cells
  25. Carlson PE, Carr KA, Janes BK, Anderson EC, Hanna PC. Transcriptional profiling of Bacillus anthracis Sterne (34F2) during iron starvation. PLoS One. 2009 Sep 21; 4(9):e6988. PMID: 19768119.
    Citations: 18     Fields:    Translation:AnimalsCells
  26. Giebel JD, Carr KA, Anderson EC, Hanna PC. The germination-specific lytic enzymes SleB, CwlJ1, and CwlJ2 each contribute to Bacillus anthracis spore germination and virulence. J Bacteriol. 2009 Sep; 191(18):5569-76. PMID: 19581364.
    Citations: 20     Fields:    Translation:AnimalsCells
  27. Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH. Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):17133-8. PMID: 18955706.
    Citations: 15     Fields:    Translation:AnimalsCells
  28. Paige C, Reid SD, Hanna PC, Claiborne A. The type III pantothenate kinase encoded by coaX is essential for growth of Bacillus anthracis. J Bacteriol. 2008 Sep; 190(18):6271-5. PMID: 18641144.
    Citations: 3     Fields:    Translation:Cells
  29. Bergman NH, Anderson EC, Swenson EE, Janes BK, Fisher N, Niemeyer MM, Miyoshi AD, Hanna PC. Transcriptional profiling of Bacillus anthracis during infection of host macrophages. Infect Immun. 2007 Jul; 75(7):3434-44. PMID: 17470545.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  30. Passalacqua KD, Bergman NH, Lee JY, Sherman DH, Hanna PC. The global transcriptional responses of Bacillus anthracis Sterne (34F2) and a Delta sodA1 mutant to paraquat reveal metal ion homeostasis imbalances during endogenous superoxide stress. J Bacteriol. 2007 Jun; 189(11):3996-4013. PMID: 17384197.
    Citations: 13     Fields:    Translation:Cells
  31. Pfleger BF, Lee JY, Somu RV, Aldrich CC, Hanna PC, Sherman DH. Characterization and analysis of early enzymes for petrobactin biosynthesis in Bacillus anthracis. Biochemistry. 2007 Apr 03; 46(13):4147-57. PMID: 17346033.
    Citations: 27     Fields:    Translation:Cells
  32. McConnell MJ, Hanna PC, Imperiale MJ. Adenovirus-based prime-boost immunization for rapid vaccination against anthrax. Mol Ther. 2007 Jan; 15(1):203-10. PMID: 17164792.
    Citations: 14     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  33. Lee JY, Janes BK, Passalacqua KD, Pfleger BF, Bergman NH, Liu H, Håkansson K, Somu RV, Aldrich CC, Cendrowski S, Hanna PC, Sherman DH. Biosynthetic analysis of the petrobactin siderophore pathway from Bacillus anthracis. J Bacteriol. 2007 Mar; 189(5):1698-710. PMID: 17189355.
    Citations: 30     Fields:    Translation:Cells
  34. Bergman NH, Passalacqua KD, Hanna PC, Qin ZS. Operon prediction for sequenced bacterial genomes without experimental information. Appl Environ Microbiol. 2007 Feb; 73(3):846-54. PMID: 17122389.
    Citations: 15     Fields:    Translation:Cells
  35. Bergman NH, Anderson EC, Swenson EE, Niemeyer MM, Miyoshi AD, Hanna PC. Transcriptional profiling of the Bacillus anthracis life cycle in vitro and an implied model for regulation of spore formation. J Bacteriol. 2006 Sep; 188(17):6092-100. PMID: 16923876.
    Citations: 41     Fields:    Translation:Cells
  36. McConnell MJ, Hanna PC, Imperiale MJ. Cytokine response and survival of mice immunized with an adenovirus expressing Bacillus anthracis protective antigen domain 4. Infect Immun. 2006 Feb; 74(2):1009-15. PMID: 16428747.
    Citations: 16     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  37. Bergman NH, Passalacqua KD, Gaspard R, Shetron-Rama LM, Quackenbush J, Hanna PC. Murine macrophage transcriptional responses to Bacillus anthracis infection and intoxication. Infect Immun. 2005 Feb; 73(2):1069-80. PMID: 15664951.
    Citations: 20     Fields:    Translation:AnimalsCells
  38. Weiner MA, Hanna PC. Macrophage-mediated germination of Bacillus anthracis endospores requires the gerH operon. Infect Immun. 2003 Jul; 71(7):3954-9. PMID: 12819082.
    Citations: 20     Fields:    Translation:AnimalsCells
  39. Read TD, Peterson SN, Tourasse N, Baillie LW, Paulsen IT, Nelson KE, Tettelin H, Fouts DE, Eisen JA, Gill SR, Holtzapple EK, Okstad OA, Helgason E, Rilstone J, Wu M, Kolonay JF, Beanan MJ, Dodson RJ, Brinkac LM, Gwinn M, DeBoy RT, Madpu R, Daugherty SC, Durkin AS, Haft DH, Nelson WC, Peterson JD, Pop M, Khouri HM, Radune D, Benton JL, Mahamoud Y, Jiang L, Hance IR, Weidman JF, Berry KJ, Plaut RD, Wolf AM, Watkins KL, Nierman WC, Hazen A, Cline R, Redmond C, Thwaite JE, White O, Salzberg SL, Thomason B, Friedlander AM, Koehler TM, Hanna PC, Kolstø AB, Fraser CM. The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria. Nature. 2003 May 01; 423(6935):81-6. PMID: 12721629.
    Citations:    
  40. Weiner MA, Read TD, Hanna PC. Identification and characterization of the gerH operon of Bacillus anthracis endospores: a differential role for purine nucleosides in germination. J Bacteriol. 2003 Feb; 185(4):1462-4. PMID: 12562819.
    Citations: 29     Fields:    Translation:Cells
  41. Ireland JA, Hanna PC. Macrophage-enhanced germination of Bacillus anthracis endospores requires gerS. Infect Immun. 2002 Oct; 70(10):5870-2. PMID: 12228320.
    Citations: 24     Fields:    Translation:AnimalsCells
  42. Ireland JA, Hanna PC. Amino acid- and purine ribonucleoside-induced germination of Bacillus anthracis DeltaSterne endospores: gerS mediates responses to aromatic ring structures. J Bacteriol. 2002 Mar; 184(5):1296-303. PMID: 11844758.
    Citations: 45     Fields:    Translation:Cells
  43. Hanna PC. Anthrax: a motor protein determines anthrax susceptibility. Curr Biol. 2001 Nov 13; 11(22):R905-6. PMID: 11719234.
    Citations:    
  44. Dixon TC, Fadl AA, Koehler TM, Swanson JA, Hanna PC. Early Bacillus anthracis-macrophage interactions: intracellular survival survival and escape. Cell Microbiol. 2000 Dec; 2(6):453-63. PMID: 11207600.
    Citations:    
  45. Dixon TC, Meselson M, Guillemin J, Hanna PC. Anthrax. N Engl J Med. 1999 Sep 09; 341(11):815-26. PMID: 10477781.
    Citations:    
  46. Hanna PC, Ireland JA. Understanding Bacillus anthracis pathogenesis. Trends Microbiol. 1999 May; 7(5):180-2. PMID: 10383221.
    Citations:    
  47. Heithoff DM, Conner CP, Hentschel U, Govantes F, Hanna PC, Mahan MJ. Coordinate intracellular expression of Salmonella genes induced during infection. J Bacteriol. 1999 Feb; 181(3):799-807. PMID: 9922242.
    Citations:    
  48. Hammond SE, Hanna PC. Lethal factor active-site mutations affect catalytic activity in vitro. Infect Immun. 1998 May; 66(5):2374-8. PMID: 9573135.
    Citations:    
  49. Heithoff DM, Conner CP, Hanna PC, Julio SM, Hentschel U, Mahan MJ. Bacterial infection as assessed by in vivo gene expression. Proc Natl Acad Sci U S A. 1997 Feb 04; 94(3):934-9. PMID: 9023360.
    Citations:    
  50. Milne JC, Blanke SR, Hanna PC, Collier RJ. Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus. Mol Microbiol. 1995 Feb; 15(4):661-6. PMID: 7783638.
    Citations: 67     Fields:    Translation:AnimalsCells
  51. Mahan MJ, Tobias JW, Slauch JM, Hanna PC, Collier RJ, Mekalanos JJ. Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host. Proc Natl Acad Sci U S A. 1995 Jan 31; 92(3):669-73. PMID: 7846034.
    Citations: 73     Fields:    Translation:AnimalsCells
  52. Hanna PC, Kruskal BA, Ezekowitz RA, Bloom BR, Collier RJ. Role of macrophage oxidative burst in the action of anthrax lethal toxin. Mol Med. 1994 Nov; 1(1):7-18. PMID: 8790597.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  53. Milne JC, Furlong D, Hanna PC, Wall JS, Collier RJ. Anthrax protective antigen forms oligomers during intoxication of mammalian cells. J Biol Chem. 1994 Aug 12; 269(32):20607-12. PMID: 8051159.
    Citations: 139     Fields:    Translation:AnimalsCells
  54. Hanna PC, Acosta D, Collier RJ. On the role of macrophages in anthrax. Proc Natl Acad Sci U S A. 1993 Nov 01; 90(21):10198-201. PMID: 8234277.
    Citations: 87     Fields:    Translation:AnimalsCells
  55. Czeczulin JR, Hanna PC, McClane BA. Cloning, nucleotide sequencing, and expression of the Clostridium perfringens enterotoxin gene in Escherichia coli. Infect Immun. 1993 Aug; 61(8):3429-39. PMID: 8335373.
    Citations:    
  56. Mahan MJ, Slauch JM, Hanna PC, Camilli A, Tobias JW, Waldor MK, Mekalanos JJ. Selection for bacterial genes that are specifically induced in host tissues: the hunt for virulence factors. Infect Agents Dis. 1993 Aug; 2(4):263-8. PMID: 8173806.
    Citations: 10     Fields:    Translation:Cells
  57. Hanna PC, Kochi S, Collier RJ. Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells. Mol Biol Cell. 1992 Nov; 3(11):1269-77. PMID: 1457831.
    Citations: 37     Fields:    Translation:Cells
  58. Hanna PC, Mietzner TA, Schoolnik GK, McClane BA. Localization of the receptor-binding region of Clostridium perfringens enterotoxin utilizing cloned toxin fragments and synthetic peptides. The 30 C-terminal amino acids define a functional binding region. J Biol Chem. 1991 Jun 15; 266(17):11037-43. PMID: 1645721.
    Citations:    
  59. Hanna PC, McClane BA. A recombinant C-terminal toxin fragment provides evidence that membrane insertion is important for Clostridium perfringens enterotoxin cytotoxicity. Mol Microbiol. 1991 Jan; 5(1):225-30. PMID: 2014001.
    Citations:    
  60. Hanna PC, Wnek AP, McClane BA. Molecular cloning of the 3' half of the Clostridium perfringens enterotoxin gene and demonstration that this region encodes receptor-binding activity. J Bacteriol. 1989 Dec; 171(12):6815-20. PMID: 2556374.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.