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profileSeung-Ki Kwok, Ph.D., M.D.

TitleMedicine (INT)
InstitutionBeth Israel Deaconess Medical Center
DepartmentMedicine
AddressBeth Israel Deaconess Medical Center
330 Brookline Ave
Boston MA 02215
Phone617 735 4176
Fax617 735 4170
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Yeon Lee J, Lee J, Ki Kwok S, Hyeon Ju J, Su Park K, Park SH. Factors Related to Blood Hydroxychloroquine Concentration in Patients With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2017 Apr; 69(4):536-542. PMID: 27390146.
    View in: PubMed
  2. Park DJ, Choi SJ, Shin K, Kim HA, Park YB, Kang SW, Kwok SK, Kim SK, Nam EJ, Sung YK, Lee J, Lee CH, Jeon CH, Lee SS. Switching profiles in a population-based cohort of rheumatoid arthritis receiving biologic therapy: results from the KOBIO registry. Clin Rheumatol. 2017 May; 36(5):1013-1022. PMID: 28243760.
    View in: PubMed
  3. Kim EK, Kwon JE, Lee SY, Lee EJ, Kim DS, Moon SJ, Lee J, Kwok SK, Park SH, Cho ML. IL-17-mediated mitochondrial dysfunction impairs apoptosis in rheumatoid arthritis synovial fibroblasts through activation of autophagy. Cell Death Dis. 2017 Jan 19; 8(1):e2565. PMID: 28102843.
    View in: PubMed
  4. Park N, Rim YA, Jung H, Kim J, Yi H, Kim Y, Jang Y, Jung SM, Lee J, Kwok SK, Park SH, Ju JH. Etanercept-Synthesising Mesenchymal Stem Cells Efficiently Ameliorate Collagen-Induced Arthritis. Sci Rep. 2017 Jan 13; 7:39593. PMID: 28084468.
    View in: PubMed
  5. Brito-Zerón P, Acar-Denizli N, Zeher M, Rasmussen A, Seror R, Theander E, Li X, Baldini C, Gottenberg JE, Danda D, Quartuccio L, Priori R, Hernandez-Molina G, Kruize AA, Valim V, Kvarnstrom M, Sene D, Gerli R, Praprotnik S, Isenberg D, Solans R, Rischmueller M, Kwok SK, Nordmark G, Suzuki Y, Giacomelli R, Devauchelle-Pensec V, Bombardieri M, Hofauer B, Bootsma H, Brun JG, Fraile G, Carsons SE, Gheita TA, Morel J, Vollenveider C, Atzeni F, Retamozo S, Horvath IF, Sivils K, Mandl T, Sandhya P, De Vita S, Sanchez-Guerrero J, van der Heijden E, Trevisani VFM, Wahren-Herlenius M, Mariette X, Ramos-Casals M. Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium. Ann Rheum Dis. 2017 Jun; 76(6):1042-1050. PMID: 27899373.
    View in: PubMed
  6. Park MJ, Lee SH, Kim EK, Lee EJ, Park SH, Kwok SK, Cho ML. Myeloid-Derived Suppressor Cells Induce the Expansion of Regulatory B Cells and Ameliorate Autoimmunity in the Sanroque Mouse Model of Systemic Lupus Erythematosus. Arthritis Rheumatol. 2016 Nov; 68(11):2717-2727. PMID: 27214349.
    View in: PubMed
  7. Park JS, Kim SM, Jung KA, Lee J, Kwok SK, Cho ML, Park SH. Inhibition of the TWEAK/Fn14 pathway attenuates autoimmune arthritis in a SKG mouse model. Histol Histopathol. 2017 May; 32(5):481-490. PMID: 27653285.
    View in: PubMed
  8. Alam J, Koh JH, Kim N, Kwok SK, Park SH, Song YW, Park K, Choi Y. Detection of autoantibodies against aquaporin-5 in the sera of patients with primary Sjögren's syndrome. Immunol Res. 2016 Aug; 64(4):848-56. PMID: 26786004; PMCID: PMC4930796.
  9. Choi JY, Kim SH, Kwok SK, Jung JI, Lee KY, Kim TJ, Kang JY. A 30-year-old female Behçet's disease patient with recurrent pleural and pericardial effusion and elevated adenosine deaminase levels: case report. J Thorac Dis. 2016 Jul; 8(7):E547-51. PMID: 27499994; PMCID: PMC4958825.
  10. Min HK, Kim JK, Lee SY, Kim EK, Lee SH, Lee J, Kwok SK, Cho ML, Park SH. Rebamipide prevents peripheral arthritis and intestinal inflammation by reciprocally regulating Th17/Treg cell imbalance in mice with curdlan-induced spondyloarthritis. J Transl Med. 2016 Jun 27; 14(1):190. PMID: 27350608; PMCID: PMC4924325.
  11. Min HK, Kim SM, Park JS, Byun JK, Lee J, Kwok SK, Park YW, Cho ML, Park SH. Fn14-Fc suppresses germinal center formation and pathogenic B cells in a lupus mouse model via inhibition of the TWEAK/Fn14 Pathway. J Transl Med. 2016 Apr 21; 14:98. PMID: 27098560; PMCID: PMC4839090.
  12. Lee J, Koh JH, Kwok SK, Park SH. The EULAR Sjögren's Syndrome Patient-Reported Index is an independent determinant of health-related utility values of Korean patients with primary Sjögren's syndrome. Clin Exp Rheumatol. 2016 Jul-Aug; 34(4):663-7. PMID: 27050672.
    View in: PubMed
  13. Lee J, Koh JH, Kwok SK, Park SH. Translation and Validation of a Korean Version of the Xerostomia Inventory in Patients with Primary Sjögren's Syndrome. J Korean Med Sci. 2016 May; 31(5):724-8. PMID: 27134493; PMCID: PMC4835597.
  14. Koh JH, Kwok SK, Lee J, Park SH. Autonomic dysfunction in primary Sjogren's syndrome: a prospective cohort analysis of 154 Korean patients. Korean J Intern Med. 2017 Jan; 32(1):165-173. PMID: 27017389.
    View in: PubMed
  15. Lee SY, Min HK, Lee SH, Shin HJ, Lee WY, Cho YG, Kwok SK, Ju JH, Cho ML, Park SH. IL-1 receptor antagonist (IL-1Ra)-Fc ameliorate autoimmune arthritis by regulation of the Th17 cells/Treg balance and arthrogenic cytokine activation. Immunol Lett. 2016 Apr; 172:56-66. PMID: 26903194.
    View in: PubMed
  16. Lee JY, Vinayagamoorthy N, Han K, Kwok SK, Ju JH, Park KS, Jung SH, Park SW, Chung YJ, Park SH. Association of Polymorphisms of Cytochrome P450 2D6 With Blood Hydroxychloroquine Levels in Patients With Systemic Lupus Erythematosus. Arthritis Rheumatol. 2016 Jan; 68(1):184-90. PMID: 26316040.
    View in: PubMed
  17. Koh JH, Myong JP, Jung SM, Lee J, Kwok SK, Park SH, Ju JH. Atypical Femoral Fracture in Rheumatoid Arthritis Patients Treated With Bisphosphonates: A Nested Case-Control Study. Arthritis Rheumatol. 2016 Jan; 68(1):77-82. PMID: 26360133.
    View in: PubMed
  18. Lim BS, Kim KS, Kwok SK, Lee WK. Retinal vasculitis associated with autoantibodies of primary Sjögren's syndrome after cataract surgery. Clin Exp Optom. 2016 Jan; 99(1):87-9. PMID: 26875858.
    View in: PubMed
  19. Min HK, Kim SM, Baek SY, Woo JW, Park JS, Cho ML, Lee J, Kwok SK, Kim SW, Park SH. Anthocyanin Extracted from Black Soybean Seed Coats Prevents Autoimmune Arthritis by Suppressing the Development of Th17 Cells and Synthesis of Proinflammatory Cytokines by Such Cells, via Inhibition of NF-?B. PLoS One. 2015; 10(11):e0138201. PMID: 26544846; PMCID: PMC4636296.
  20. Lim SA, Nam S, Kwok SK, Park SH, Chung SH. Serologic Markers Are Associated With Ocular Staining Score in Primary Sjögren Syndrome. Cornea. 2015 Nov; 34(11):1466-70. PMID: 26356755.
    View in: PubMed
  21. Lee SY, Jung YO, Kim DJ, Kang CM, Moon YM, Heo YJ, Oh HJ, Park SJ, Yang SH, Kwok SK, Ju JH, Park SH, Sung YC, Kim HY, Cho ML. IL-12p40 Homodimer Ameliorates Experimental Autoimmune Arthritis. J Immunol. 2015 Oct 01; 195(7):3001-10. PMID: 26324771; PMCID: PMC4574520.
  22. Lee J, Lee SY, Lee J, Lee J, Baek S, Lee DG, Kim EK, Lee SH, Cho ML, Kwok SK, Ju JH, Park SH. Monosodium urate crystal-induced triggering receptor expressed on myeloid cells 1 is associated with acute gouty inflammation. Rheumatology (Oxford). 2016 Jan; 55(1):156-61. PMID: 26320130.
    View in: PubMed
  23. Koh JH, Lee J, Chung SH, Kwok SK, Park SH. Relation of Autoimmune Cytopenia to Glandular and Systemic Manifestations in Primary Sjögren Syndrome: Analysis of 113 Korean Patients. J Rheumatol. 2015 Oct; 42(10):1817-24. PMID: 26276967.
    View in: PubMed
  24. Seo JE, Hasan M, Han JS, Kang MJ, Jung BH, Kwok SK, Kim HY, Kwon OS. Experimental autoimmune encephalomyelitis and age-related correlations of NADPH oxidase, MMP-9, and cell adhesion molecules: The increased disease severity and blood-brain barrier permeability in middle-aged mice. J Neuroimmunol. 2015 Oct 15; 287:43-53. PMID: 26439961.
    View in: PubMed
  25. Koh JH, Jung SM, Lee JJ, Kang KY, Kwok SK, Park SH, Ju JH. Radiographic Structural Damage Is Worse in the Dominant than the Non-Dominant Hand in Individuals with Early Rheumatoid Arthritis. PLoS One. 2015; 10(8):e0135409. PMID: 26247204; PMCID: PMC4527732.
  26. Kang KY, Jeon CH, Choi SJ, Yoon BY, Choi CB, Lee CH, Suh CH, Lee CW, Cho CS, Nam EJ, Koh EM, Kim HY, Choi HJ, Kim HA, Jun JB, Lee J, Kim J, Ji JD, Min JK, Kim KJ, Shin K, So MW, Kwon SR, Kim SK, Nah SS, Kwok SK, Lee SK, Lee SW, Park SH, Park W, Park YB, Lee YH, Lee SS, Yoo DH. Survival and prognostic factors in patients with connective tissue disease-associated pulmonary hypertension by echocardiography: results from a Korean nationwide registry. Int J Rheum Dis. 2015 Jul 27. PMID: 26214170.
    View in: PubMed
  27. Min HK, Lee B, Kwok SK, Ju JH, Kim WU, Park YM, Park SH. Allopurinol hypersensitivity syndrome in patients with hematological malignancies: characteristics and clinical outcomes. Korean J Intern Med. 2015 Jul; 30(4):521-30. PMID: 26161019; PMCID: PMC4497340.
  28. Kim JM, Park SH, Kim HY, Kwok SK. A Plasmacytoid Dendritic Cells-Type I Interferon Axis Is Critically Implicated in the Pathogenesis of Systemic Lupus Erythematosus. Int J Mol Sci. 2015 Jun 23; 16(6):14158-70. PMID: 26110387; PMCID: PMC4490545.
  29. Lee J, Baek S, Lee J, Lee J, Lee DG, Park MK, Cho ML, Park SH, Kwok SK. Digoxin ameliorates autoimmune arthritis via suppression of Th17 differentiation. Int Immunopharmacol. 2015 May; 26(1):103-11. PMID: 25819229.
    View in: PubMed
  30. Lee J, Lee JY, Lee JH, Jung SM, Suh YS, Koh JH, Kwok SK, Ju JH, Park KS, Park SH. Visceral fat obesity is highly associated with primary gout in a metabolically obese but normal weighted population: a case control study. Arthritis Res Ther. 2015 Mar 24; 17:79. PMID: 25889813; PMCID: PMC4381370.
  31. Lim SA, Nam DH, Lee JH, Kwok SK, Park SH, Chung SH. Association of IL-21 cytokine with severity of primary Sjögren syndrome dry eye. Cornea. 2015 Mar; 34(3):248-52. PMID: 25603233.
    View in: PubMed
  32. Min HK, Lee JH, Jung SM, Lee J, Kang KY, Kwok SK, Ju JH, Park KS, Park SH. Pulmonary hypertension in systemic lupus erythematosus: an independent predictor of patient survival. Korean J Intern Med. 2015 Mar; 30(2):232-41. PMID: 25750566; PMCID: PMC4351331.
  33. Kwok SK, Lee J, Yu D, Kang KY, Cho ML, Kim HR, Ju JH, Lee SH, Park SH, Kim HY. A pathogenetic role for IL-21 in primary Sjögren syndrome. Nat Rev Rheumatol. 2015 06; 11(6):368-74. PMID: 25584898.
    View in: PubMed
  34. Jung SM, Ju JH, Park MS, Kwok SK, Park KS, Kim HY, Yim HW, Park SH. Risk of tuberculosis in patients treated with anti-tumor necrosis factor therapy: a nationwide study in South Korea, a country with an intermediate tuberculosis burden. Int J Rheum Dis. 2015 Mar; 18(3):323-30. PMID: 25557144.
    View in: PubMed
  35. Jung SM, Lee J, Baek SY, Lee JH, Lee J, Park KS, Park SH, Kim HY, Kwok SK. The Interleukin 33/ST2 axis in patients with primary Sjögren syndrome: expression in serum and salivary glands, and the clinical association. J Rheumatol. 2015 Feb; 42(2):264-71. PMID: 25512474.
    View in: PubMed
  36. Park MJ, Kwok SK, Lee SH, Kim EK, Park SH, Cho ML. Adipose tissue-derived mesenchymal stem cells induce expansion of interleukin-10-producing regulatory B cells and ameliorate autoimmunity in a murine model of systemic lupus erythematosus. Cell Transplant. 2015; 24(11):2367-77. PMID: 25506685.
    View in: PubMed
  37. Lee JH, Kwok SK, Jung SM, Lee J, Lee JS, Baek SY, Kim EK, Ju JH, Park SH, Kim HY. Role of fractalkine in the pathogenesis of primary Sjögren syndrome: increased serum levels of fractalkine, its expression in labial salivary glands, and the association with clinical manifestations. J Rheumatol. 2014 Dec; 41(12):2425-38. PMID: 25320221.
    View in: PubMed
  38. Jung SM, Ju JH, Kwok SK, Park KS, Park SH. Multiple osteonecrotic lesions mimicking a piano keyboard in the spine of a patient with catastrophic antiphospholipid syndrome. Arthritis Rheumatol. 2014 Oct; 66(10):2914. PMID: 24838647.
    View in: PubMed
  39. Kwok SK. Could tofacitinib, the first oral small-molecule inhibitor proven for use in active rheumatoid arthritis (RA) patients with insufficient response to methotrexate, be the breakthrough drug for RA? Korean J Intern Med. 2014 Sep; 29(5):577-9. PMID: 25228832; PMCID: PMC4164720.
  40. Baek SY, Lee J, Lee DG, Park MK, Lee J, Kwok SK, Cho ML, Park SH. Ursolic acid ameliorates autoimmune arthritis via suppression of Th17 and B cell differentiation. Acta Pharmacol Sin. 2014 Sep; 35(9):1177-87. PMID: 25087995; PMCID: PMC4155530.
  41. Lee J, Shin EK, Lee SY, Her YM, Park MK, Kwok SK, Ju JH, Park KS, Kim HY, Cho ML, Park SH. Oestrogen up-regulates interleukin-21 production by CD4(+) T lymphocytes in patients with systemic lupus erythematosus. Immunology. 2014 Aug; 142(4):573-80. PMID: 24495300; PMCID: PMC4107667.
  42. Lee JH, Suh YS, Koh JH, Jung SM, Lee JJ, Kwok SK, Ju JH, Park KS, Park SH. The risk of osteoporotic fractures according to the FRAX model in Korean patients with rheumatoid arthritis. J Korean Med Sci. 2014 Aug; 29(8):1082-9. PMID: 25120317; PMCID: PMC4129199.
  43. Jhun J, Lee J, Byun JK, Kim EK, Woo JW, Lee JH, Kwok SK, Ju JH, Park KS, Kim HY, Park SH, Cho ML. Red ginseng extract ameliorates autoimmune arthritis via regulation of STAT3 pathway, Th17/Treg balance, and osteoclastogenesis in mice and human. Mediators Inflamm. 2014; 2014:351856. PMID: 25147435; PMCID: PMC4132415.
  44. Hwang J, Chung SH, Jeon S, Kwok SK, Park SH, Kim MS. Comparison of clinical efficacies of autologous serum eye drops in patients with primary and secondary Sjögren syndrome. Cornea. 2014 Jul; 33(7):663-7. PMID: 24886995.
    View in: PubMed
  45. Kang KY, Kim IJ, Jung SM, Kwok SK, Ju JH, Park KS, Hong YS, Park SH. Incidence and predictors of morphometric vertebral fractures in patients with ankylosing spondylitis. Arthritis Res Ther. 2014 Jun 16; 16(3):R124. PMID: 24935156; PMCID: PMC4095597.
  46. Ju JH, Yoon SH, Kang KY, Kim IJ, Kwok SK, Park SH, Kim HY, Lee WC, Cho CS. Prevalence of systemic lupus erythematosus in South Korea: an administrative database study. J Epidemiol. 2014; 24(4):295-303. PMID: 24857955; PMCID: PMC4074634.
  47. Park MK, Park JS, Park EM, Lim MA, Kim SM, Lee DG, Baek SY, Yang EJ, Woo JW, Lee J, Kwok SK, Kim HY, Cho ML, Park SH. Halofuginone ameliorates autoimmune arthritis in mice by regulating the balance between Th17 and Treg cells and inhibiting osteoclastogenesis. Arthritis Rheumatol. 2014 May; 66(5):1195-207. PMID: 24782183.
    View in: PubMed
  48. Jung SM, Kim HS, Kim HR, Kim NY, Lee JH, Kim J, Kwok SK, Park KS, Park SH, Kim HY, Ju JH. Immunogenicity of anti-tumour necrosis factor therapy in Korean patients with rheumatoid arthritis and ankylosing spondylitis. Int Immunopharmacol. 2014 Jul; 21(1):20-5. PMID: 24752013.
    View in: PubMed
  49. Park JS, Kwok SK, Lim MA, Kim EK, Ryu JG, Kim SM, Oh HJ, Ju JH, Park SH, Kim HY, Cho ML. STA-21, a promising STAT-3 inhibitor that reciprocally regulates Th17 and Treg cells, inhibits osteoclastogenesis in mice and humans and alleviates autoimmune inflammation in an experimental model of rheumatoid arthritis. Arthritis Rheumatol. 2014 Apr; 66(4):918-29. PMID: 24757144.
    View in: PubMed
  50. Park JS, Lee J, Lim MA, Kim EK, Kim SM, Ryu JG, Lee JH, Kwok SK, Park KS, Kim HY, Park SH, Cho ML. JAK2-STAT3 blockade by AG490 suppresses autoimmune arthritis in mice via reciprocal regulation of regulatory T Cells and Th17 cells. J Immunol. 2014 May 01; 192(9):4417-24. PMID: 24688026.
    View in: PubMed
  51. Moon YM, Lee J, Lee SY, Her YM, Ryu JG, Kim EK, Son HJ, Kwok SK, Ju JH, Yang CW, Park SH, Kim HY, Cho ML. Gene associated with retinoid-interferon-induced mortality 19 attenuates murine autoimmune arthritis by regulation of th17 and treg cells. Arthritis Rheumatol. 2014 Mar; 66(3):569-78. PMID: 24574216.
    View in: PubMed
  52. Lee JH, Kwok SK, Ju JH, Park SH, Park KS. Ultrasound examination of wrist compartments in swollen wrists of patients with rheumatoid arthritis. Mod Rheumatol. 2015 Jan; 25(1):164-5. PMID: 24471995.
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  53. Kwok SK. The author response. J Korean Med Sci. 2014 Jan; 29(1):153-4. PMID: 24571039.
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  54. Suh YS, Kwok SK, Ju JH, Park KS, Park SH, Yoon CH. Safe re-administration of tumor necrosis factor-alpha (TNFa) inhibitors in patients with rheumatoid arthritis or ankylosing spondylitis who developed active tuberculosis on previous anti-TNFa therapy. J Korean Med Sci. 2014 Jan; 29(1):38-42. PMID: 24431903; PMCID: PMC3890474.
  55. Moon SJ, Hong YS, Ju JH, Kwok SK, Park SH, Min JK. Increased levels of interleukin 34 in serum and synovial fluid are associated with rheumatoid factor and anticyclic citrullinated peptide antibody titers in patients with rheumatoid arthritis. J Rheumatol. 2013 Nov; 40(11):1842-9. PMID: 23996288.
    View in: PubMed
  56. Kim DJ, Baek SY, Park MK, Park KS, Lee JH, Park SH, Kim HY, Kwok SK. Serum level of interleukin-33 and soluble ST2 and their association with disease activity in patients with Behcet's disease. J Korean Med Sci. 2013 Aug; 28(8):1145-53. PMID: 23960440; PMCID: PMC3744701.
  57. Lee JH, Kwok SK, Park SH, Kim HY, Park KS. Medial tibial stress syndrome progressing to tibial fracture in rheumatoid arthritis. Int J Rheum Dis. 2014 Jan; 17(1):125-6. PMID: 24472277.
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  58. Park JS, Kwok SK, Lim MA, Oh HJ, Kim EK, Jhun JY, Ju JH, Park KS, Park YW, Park SH, Kim HY, Cho YG, Cho ML. TWEAK promotes osteoclastogenesis in rheumatoid arthritis. Am J Pathol. 2013 Sep; 183(3):857-67. PMID: 23845567.
    View in: PubMed
  59. Lee DG, Woo JW, Kwok SK, Cho ML, Park SH. MRP8 promotes Th17 differentiation via upregulation of IL-6 production by fibroblast-like synoviocytes in rheumatoid arthritis. Exp Mol Med. 2013 Apr 26; 45:e20. PMID: 23619188; PMCID: PMC3641402.
  60. Moon SJ, Oh EJ, Kim Y, Kim KS, Kwok SK, Ju JH, Park KS, Kim HY, Park SH. Diversity of killer cell immunoglobulin-like receptor genes in uveitis associated with autoimmune diseases: ankylosing spondylitis and Behçet disease. Ocul Immunol Inflamm. 2013 Apr; 21(2):135-43. PMID: 23697859.
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  61. Park JS, Lim MA, Cho ML, Ryu JG, Moon YM, Jhun JY, Byun JK, Kim EK, Hwang SY, Ju JH, Kwok SK, Kim HY. p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice. Arthritis Rheum. 2013 Apr; 65(4):949-59. PMID: 23280308.
    View in: PubMed
  62. Kim EJ, Lee J, Ryu YS, Kim JM, Jeong YG, Kwok SK, Ju JH, Park KS, Park SH, Choi HB, Kim TG, Kim HY. Shared epitope and radiologic progression are less prominent in elderly onset RA than young onset RA. Rheumatol Int. 2013 Aug; 33(8):2135-40. PMID: 23443331.
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  63. Lee SY, Kwok SK, Son HJ, Ryu JG, Kim EK, Oh HJ, Cho ML, Ju JH, Park SH, Kim HY. IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation. Arthritis Res Ther. 2013 Feb 20; 15(1):R31. PMID: 23421940; PMCID: PMC3672783.
  64. Moon SJ, Ahn IE, Jung H, Yi H, Kim J, Kim Y, Kwok SK, Park KS, Min JK, Park SH, Kim HY, Ju JH. Temporal differential effects of proinflammatory cytokines on osteoclastogenesis. Int J Mol Med. 2013 Apr; 31(4):769-77. PMID: 23403591; PMCID: PMC3621814.
  65. Moon SJ, Ahn IE, Kwok SK, Park KS, Min JK, Park SH, Kim HY, Ju JH. Periarticular osteoporosis is a prominent feature in early rheumatoid arthritis: estimation using shaft to periarticular bone mineral density ratio. J Korean Med Sci. 2013 Feb; 28(2):287-94. PMID: 23399828; PMCID: PMC3565142.
  66. Park JS, Jung YO, Oh HJ, Park SJ, Heo YJ, Kang CM, Kwok SK, Ju JH, Park KS, Cho ML, Sung YC, Park SH, Kim HY. Interleukin-27 suppresses osteoclastogenesis via induction of interferon-?. Immunology. 2012 Dec; 137(4):326-35. PMID: 22812379; PMCID: PMC3530088.
  67. Lee JH, Choi ST, Kim JS, Yoon BY, Kwok SK, Kim HS, Kim YS, Song JS, Lee SH, Kim HR. Clinical characteristics and prognostic factors for relapse in patients with polymyalgia rheumatica (PMR). Rheumatol Int. 2013 Jun; 33(6):1475-80. PMID: 23184033.
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  68. Ryu YS, Park SH, Lee J, Kwok SK, Ju JH, Kim HY, Jeon CH. Follow-up of primary Sjogren's syndrome patients presenting positive anti-cyclic citrullinated peptides antibody. Rheumatol Int. 2013 Jun; 33(6):1443-6. PMID: 23179261.
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  69. Ju JH, Heo YJ, Cho ML, Jhun JY, Park JS, Lee SY, Oh HJ, Moon SJ, Kwok SK, Park KS, Park SH, Kim HY. Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells. Arthritis Rheum. 2012 Nov; 64(11):3543-52. PMID: 22736176.
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  70. Kim DJ, Kwok SK, Park SH, Kim HY, Park KS. Hole in the elbow of a patient with rheumatoid arthritis. Arthritis Rheum. 2012 Nov; 64(11):3759. PMID: 22833418.
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  71. Moon SJ, Park HS, Kwok SK, Ju JH, Kim HY, Park SH. Predictors of end-stage renal disease and recurrence of lupus activity after initiation of dialysis in patients with lupus nephritis. Clin Exp Rheumatol. 2013 Jan-Feb; 31(1):31-9. PMID: 22935632.
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  72. Yang HK, Moon SJ, Shin JH, Kwok SK, Park KS, Park SH, Kim HY, Ju JH. Regression of syndesmophyte after bone marrow transplantation for acute myeloid leukemia in a patient with ankylosing spondylitis: a case report. J Med Case Rep. 2012 Aug 21; 6:250. PMID: 22909092; PMCID: PMC3459693.
  73. Park MK, Jhun JY, Lee SY, Oh HJ, Park MJ, Byun JK, Yoon BY, Park EM, Lee DG, Kwok SK, Park SH, Kim HY, Cho ML. Retinal attenuates inflammatory arthritis by reciprocal regulation of IL-17-producing T cells and Foxp3(+) regulatory T cells and the inhibition of osteoclastogenesis. Immunol Lett. 2012 Nov-Dec; 148(1):59-68. PMID: 22841964.
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  74. Lee SA, Kahng J, Kim Y, Park YJ, Han K, Kwok SK, Park SH, Oh EJ. Comparative study of immunofluorescent antinuclear antibody test and line immunoassay detecting 15 specific autoantibodies in patients with systemic rheumatic disease. J Clin Lab Anal. 2012 Jul; 26(4):307-14. PMID: 22811366.
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  75. Kwok SK, Park MK, Cho ML, Oh HJ, Park EM, Lee DG, Lee J, Kim HY, Park SH. Retinoic acid attenuates rheumatoid inflammation in mice. J Immunol. 2012 Jul 15; 189(2):1062-71. PMID: 22696440.
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  76. Kwok SK, Cho ML, Her YM, Oh HJ, Park MK, Lee SY, Woo YJ, Ju JH, Park KS, Kim HY, Park SH. TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren's syndrome. Arthritis Res Ther. 2012 Mar 14; 14(2):R64. PMID: 22417709; PMCID: PMC3446432.
  77. Kwok SK, Cho ML, Park MK, Oh HJ, Park JS, Her YM, Lee SY, Youn J, Ju JH, Park KS, Kim SI, Kim HY, Park SH. Interleukin-21 promotes osteoclastogenesis in humans with rheumatoid arthritis and in mice with collagen-induced arthritis. Arthritis Rheum. 2012 Mar; 64(3):740-51. PMID: 21968544.
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  78. Kim KJ, Kwok SK, Park YJ, Kim WU, Cho CS. Low C3 levels is associated with neutropenia in a proportion of patients with myelodysplastic syndrome: retrospective analysis. Int J Rheum Dis. 2012 Feb; 15(1):86-94. PMID: 22324951.
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  79. Kim JM, Kwok SK, Ju JH, Kim HY, Park SH. Reactive hemophagocytic syndrome in adult Korean patients with systemic lupus erythematosus: a case-control study and literature review. J Rheumatol. 2012 Jan; 39(1):86-93. PMID: 22174206.
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  80. Ryu YS, Park SH, Kim JM, Kim EJ, Lee J, Kwok SK, Ju JH, Kim HY. A case of leukoencephalopathy associated with adalimumab-treated rheumatoid arthritis and a review of literature. Rheumatol Int. 2012 Nov; 32(11):3481-5. PMID: 22065075.
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  81. Kang KY, Kim HO, Kwok SK, Ju JH, Park KS, Sun DI, Jhun JY, Oh HJ, Park SH, Kim HY. Impact of interleukin-21 in the pathogenesis of primary Sjögren's syndrome: increased serum levels of interleukin-21 and its expression in the labial salivary glands. Arthritis Res Ther. 2011; 13(5):R179. PMID: 22030011; PMCID: PMC3308114.
  82. Moon SJ, Kwok SK, Ju JH, Park KS, Park SH, Cho CS, Kim HY. Predictors of chronic kidney disease in Korean patients with lupus nephritis. J Rheumatol. 2011 Dec; 38(12):2588-97. PMID: 21965650.
    View in: PubMed
  83. Park MK, Her YM, Cho ML, Oh HJ, Park EM, Kwok SK, Ju JH, Park KS, Min DS, Kim HY, Park SH. IL-15 promotes osteoclastogenesis via the PLD pathway in rheumatoid arthritis. Immunol Lett. 2011 Sep 30; 139(1-2):42-51. PMID: 21620893.
    View in: PubMed
  84. Kang KY, Lee KY, Kwok SK, Ju JH, Park KS, Hong YS, Kim HY, Park SH. The change of bone mineral density according to treatment agents in patients with ankylosing spondylitis. Joint Bone Spine. 2011 Mar; 78(2):188-93. PMID: 20621536.
    View in: PubMed
  85. Moon SJ, Kwok SK, Park KS, Kim WU, Park SH, Kim HY. Simultaneous presentation of hemophagocytic syndrome and mesenteric vasculitis in a patient with systemic lupus erythematosus. Mod Rheumatol. 2011 Jun; 21(3):330-3. PMID: 21229376.
    View in: PubMed
  86. Kim JM, Kwok SK, Ju JH, Park KS, Park GS, Kim HY, Park SH. Macrophage activation syndrome resistant to medical therapy in a patient with systemic lupus erythematosus and its remission with splenectomy. Rheumatol Int. 2013 Mar; 33(3):767-71. PMID: 21120496.
    View in: PubMed
  87. Moon SJ, Park MK, Oh HJ, Lee SY, Kwok SK, Cho ML, Ju JH, Park KS, Kim HY, Park SH. Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts. Korean J Intern Med. 2010 Dec; 25(4):429-35. PMID: 21179282; PMCID: PMC2997973.
  88. Kwok SK, Ju JH, Park KS, Park SH, Kim HY. Clinical Images: Entero-Behçet's disease. Arthritis Rheum. 2010 Apr; 62(4):1202. PMID: 20131289.
    View in: PubMed
  89. Park KS, Kwok SK, Ju JH, Park SH, Kim HY. Clinical image: massive bony erosions in the shoulder. Arthritis Rheum. 2010 Feb; 62(2):382. PMID: 20112394.
    View in: PubMed
  90. Heo YJ, Joo YB, Oh HJ, Park MK, Heo YM, Cho ML, Kwok SK, Ju JH, Park KS, Cho SG, Park SH, Kim HY, Min JK. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol Lett. 2010 Jan 04; 127(2):150-6. PMID: 19895848.
    View in: PubMed
  91. Park KS, Park MJ, Cho ML, Kwok SK, Ju JH, Ko HJ, Park SH, Kim HY. Type II collagen oral tolerance; mechanism and role in collagen-induced arthritis and rheumatoid arthritis. Mod Rheumatol. 2009; 19(6):581-9. PMID: 19697097.
    View in: PubMed
  92. Ko HJ, Cho ML, Lee SY, Oh HJ, Heo YJ, Moon YM, Kang CM, Kwok SK, Ju JH, Park SH, Park KS, Kim HY. CTLA4-Ig modifies dendritic cells from mice with collagen-induced arthritis to increase the CD4+CD25+Foxp3+ regulatory T cell population. J Autoimmun. 2010 Mar; 34(2):111-20. PMID: 19665867.
    View in: PubMed
  93. Ju JH, Min JK, Jung CK, Oh SN, Kwok SK, Kang KY, Park KS, Ko HJ, Yoon CH, Park SH, Cho CS, Kim HY. Lupus mesenteric vasculitis can cause acute abdominal pain in patients with SLE. Nat Rev Rheumatol. 2009 May; 5(5):273-81. PMID: 19412194.
    View in: PubMed
  94. Yoo SA, Kwok SK, Kim WU. Proinflammatory role of vascular endothelial growth factor in the pathogenesis of rheumatoid arthritis: prospects for therapeutic intervention. Mediators Inflamm. 2008; 2008:129873. PMID: 19223981; PMCID: PMC2638142.
  95. Kwok SK, Lee JY, Park SH, Cho ML, Min SY, Park SH, Kim HY, Cho YG. Dysfunctional interferon-alpha production by peripheral plasmacytoid dendritic cells upon Toll-like receptor-9 stimulation in patients with systemic lupus erythematosus. Arthritis Res Ther. 2008; 10(2):R29. PMID: 18321389; PMCID: PMC2453773.
  96. Kwok SK, Seo SH, Ju JH, Yoon CH, Park SC, Kim BS, Kim HY, Park SH. Cryptococcal meningitis presenting with isolated sixth cranial nerve palsy in a patient with systemic lupus erythematosus. J Korean Med Sci. 2008 Feb; 23(1):153-5. PMID: 18303219; PMCID: PMC2526483.
  97. Ju JH, Cho ML, Jhun JY, Park MJ, Oh HJ, Min SY, Cho YG, Hwang SY, Kwok SK, Seo SH, Yoon CH, Park SH, Kim HY. Oral administration of type-II collagen suppresses IL-17-associated RANKL expression of CD4+ T cells in collagen-induced arthritis. Immunol Lett. 2008 Apr 15; 117(1):16-25. PMID: 18242716.
    View in: PubMed
  98. Kim WU, Kwok SK, Hong KH, Yoo SA, Kong JS, Choe J, Cho CS. Soluble Fas ligand inhibits angiogenesis in rheumatoid arthritis. Arthritis Res Ther. 2007; 9(2):R42. PMID: 17459170; PMCID: PMC1906820.
  99. Kwok SK, Seo SH, Kim HS, Ju JH, Yoon CH, Park SH, Kim HY. Pneumatosis cystoides intestinalis in relapsing polychondritis. Clin Rheumatol. 2007 Sep; 26(9):1565-7. PMID: 17047889.
    View in: PubMed
  100. Ju JH, Kwok SK, Seo SH, Yoon CH, Kim HY, Park SH. Successful treatment of life-threatening intestinal ulcer in Behçet's disease with infliximab: rapid healing of Behçet's ulcer with infliximab. Clin Rheumatol. 2007 Aug; 26(8):1383-5. PMID: 17039261.
    View in: PubMed
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