Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Bruce Michael Spiegelman, Ph.D.

Co-Author

This page shows the publications co-authored by Bruce Spiegelman and Pere Puigserver.
Connection Strength

2.600
  1. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature. 2003 May 29; 423(6939):550-5.
    View in: PubMed
    Score: 0.286
  2. Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr Rev. 2003 Feb; 24(1):78-90.
    View in: PubMed
    Score: 0.280
  3. Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Mol Cell. 2001 Nov; 8(5):971-82.
    View in: PubMed
    Score: 0.257
  4. Activation of PPARgamma coactivator-1 through transcription factor docking. Science. 1999 Nov 12; 286(5443):1368-71.
    View in: PubMed
    Score: 0.224
  5. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 1998 Mar 20; 92(6):829-39.
    View in: PubMed
    Score: 0.200
  6. PGC1a expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell. 2013 Mar 18; 23(3):287-301.
    View in: PubMed
    Score: 0.140
  7. TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell. 2012 Sep 28; 151(1):96-110.
    View in: PubMed
    Score: 0.137
  8. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature. 2005 Mar 03; 434(7029):113-8.
    View in: PubMed
    Score: 0.081
  9. Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6570-5.
    View in: PubMed
    Score: 0.076
  10. Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. Genes Dev. 2004 Feb 01; 18(3):278-89.
    View in: PubMed
    Score: 0.075
  11. Suppression of beta cell energy metabolism and insulin release by PGC-1alpha. Dev Cell. 2003 Jul; 5(1):73-83.
    View in: PubMed
    Score: 0.072
  12. PGC-1beta in the regulation of hepatic glucose and energy metabolism. J Biol Chem. 2003 Aug 15; 278(33):30843-8.
    View in: PubMed
    Score: 0.072
  13. Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proc Natl Acad Sci U S A. 2003 Apr 01; 100(7):4012-7.
    View in: PubMed
    Score: 0.071
  14. Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature. 2002 Aug 15; 418(6899):797-801.
    View in: PubMed
    Score: 0.068
  15. Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor. J Biol Chem. 2002 Jan 18; 277(3):1645-8.
    View in: PubMed
    Score: 0.065
  16. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature. 2001 Sep 13; 413(6852):131-8.
    View in: PubMed
    Score: 0.064
  17. Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc Natl Acad Sci U S A. 2001 Mar 27; 98(7):3820-5.
    View in: PubMed
    Score: 0.061
  18. Regulation of adipogenesis and energy balance by PPARgamma and PGC-1. Int J Obes Relat Metab Disord. 2000 Nov; 24 Suppl 4:S8-10.
    View in: PubMed
    Score: 0.060
  19. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol Cell. 2000 Aug; 6(2):307-16.
    View in: PubMed
    Score: 0.059
  20. Transcriptional regulation of adipogenesis. Genes Dev. 2000 Jun 01; 14(11):1293-307.
    View in: PubMed
    Score: 0.058
  21. Transcriptional activation of adipogenesis. Curr Opin Cell Biol. 1999 Dec; 11(6):689-94.
    View in: PubMed
    Score: 0.056
  22. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell. 1999 Jul 09; 98(1):115-24.
    View in: PubMed
    Score: 0.055
  23. p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. Mol Cell Biol. 2004 Apr; 24(7):3057-67.
    View in: PubMed
    Score: 0.019
  24. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003 Jul; 34(3):267-73.
    View in: PubMed
    Score: 0.018
  25. Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1alpha) expression in the murine brain. Brain Res. 2003 Jan 31; 961(2):255-60.
    View in: PubMed
    Score: 0.017
  26. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature. 2001 Sep 13; 413(6852):179-83.
    View in: PubMed
    Score: 0.016
  27. Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. J Biol Chem. 2000 May 26; 275(21):16302-8.
    View in: PubMed
    Score: 0.015
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.