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Jani Pertti Kristian Saksi

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Prentice KJ, Saksi J, Hotamisligil GS. Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses. J Lipid Res. 2019 04; 60(4):734-740. PMID: 30705117.
    Citations:    Fields:    
  2. Nuotio K, Ijäs P, Heikkilä HM, Koskinen SM, Saksi J, Vikatmaa P, Sorto P, Mäkitie L, Eriksson H, Kasari S, Silvennoinen H, Valanne L, Mäyränpää MI, Kovanen PT, Soinne L, Lindsberg PJ. Morphology and histology of silent and symptom-causing atherosclerotic carotid plaques - Rationale and design of the Helsinki Carotid Endarterectomy Study 2 (the HeCES2). Ann Med. 2018 09; 50(6):501-510. PMID: 30010425.
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  3. Widenmaier SB, Snyder NA, Nguyen TB, Arduini A, Lee GY, Arruda AP, Saksi J, Bartelt A, Hotamisligil GS. NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis. Cell. 2017 Nov 16; 171(5):1094-1109.e15. PMID: 29149604.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  4. Lehti S, Nguyen SD, Belevich I, Vihinen H, Heikkilä HM, Soliymani R, Käkelä R, Saksi J, Jauhiainen M, Grabowski GA, Kummu O, Hörkkö S, Baumann M, Lindsberg PJ, Jokitalo E, Kovanen PT, Öörni K. Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties. Am J Pathol. 2018 02; 188(2):525-538. PMID: 29154769.
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  5. Ijäs P, Melkas S, Saksi J, Jula A, Jauhiainen M, Oksala N, Pohjasvaara T, Kaste M, Karhunen PJ, Lindsberg P, Erkinjuntti T. Haptoglobin Hp2 Variant Promotes Premature Cardiovascular Death in Stroke Survivors. Stroke. 2017 06; 48(6):1463-1469. PMID: 28487337.
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  6. Nuotio K, Soinne L, Hänninen H, Saksi J, Tuimala J, Jula A, Kovanen PT, Kaste M, Ijäs P, Lindsberg PJ. Life-threatening coronary disease is prevalent in patients with stenosing carotid artery disease. Int J Stroke. 2015 Dec; 10(8):1217-23. PMID: 26311319.
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  7. Mattila OS, Rantanen V, Saksi J, Strbian D, Pikkarainen T, Hautaniemi S, Lindsberg PJ. Workflow for automated quantification of cerebromicrovascular gelatinase activity. Microvasc Res. 2015 Jan; 97:19-24. PMID: 25242681.
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  8. Saksi J, Ijäs P, Mäyränpää MI, Nuotio K, Isoviita PM, Tuimala J, Lehtonen-Smeds E, Kaste M, Jula A, Sinisalo J, Nieminen MS, Lokki ML, Perola M, Havulinna AS, Salomaa V, Kettunen J, Jauhiainen M, Kovanen PT, Lindsberg PJ. Low-expression variant of fatty acid-binding protein 4 favors reduced manifestations of atherosclerotic disease and increased plaque stability. Circ Cardiovasc Genet. 2014 Oct; 7(5):588-98. PMID: 25122052.
    Citations:    
  9. Marinkovic I, Mattila OS, Strbian D, Meretoja A, Shekhar S, Saksi J, Abo-Ramadan U, Rantanen V, Lindsberg PJ, Tatlisumak T. Evolution of intracerebral hemorrhage after intravenous tPA: reversal of harmful effects with mast cell stabilization. J Cereb Blood Flow Metab. 2014 Jan; 34(1):176-81. PMID: 24169849.
    Citations:    
  10. Ijäs P, Saksi J, Soinne L, Tuimala J, Jauhiainen M, Jula A, Kähönen M, Kesäniemi YA, Kovanen PT, Kaste M, Lindsberg PJ. Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events. Atherosclerosis. 2013 Oct; 230(2):228-34. PMID: 24075749.
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  11. Mattila OS, Strbian D, Saksi J, Pikkarainen TO, Rantanen V, Tatlisumak T, Lindsberg PJ. Cerebral mast cells mediate blood-brain barrier disruption in acute experimental ischemic stroke through perivascular gelatinase activation. Stroke. 2011 Dec; 42(12):3600-5. PMID: 21980200.
    Citations:    
  12. Saksi J, Ijäs P, Nuotio K, Sonninen R, Soinne L, Salonen O, Saimanen E, Tuimala J, Lehtonen-Smeds EM, Kaste M, Kovanen PT, Lindsberg PJ. Gene expression differences between stroke-associated and asymptomatic carotid plaques. J Mol Med (Berl). 2011 Oct; 89(10):1015-26. PMID: 21607540.
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  13. Anttila J, Heinonen P, Nenonen T, Pino A, Iwaï H, Kauppi E, Soliymani R, Baumann M, Saksi J, Suni N, Haltia T. Is coproporphyrin III a copper-acquisition compound in Paracoccus denitrificans? Biochim Biophys Acta. 2011 Mar; 1807(3):311-8. PMID: 21216223.
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  14. Isoviita PM, Nuotio K, Saksi J, Turunen R, Ijäs P, Pitkäniemi J, Soinne L, Kaste M, Kovanen PT, Lindsberg PJ. An imbalance between CD36 and ABCA1 protein expression favors lipid accumulation in stroke-prone ulcerated carotid plaques. Stroke. 2010 Feb; 41(2):389-93. PMID: 20056927.
    Citations:    
  15. Sairanen T, Szepesi R, Karjalainen-Lindsberg ML, Saksi J, Paetau A, Lindsberg PJ. Neuronal caspase-3 and PARP-1 correlate differentially with apoptosis and necrosis in ischemic human stroke. Acta Neuropathol. 2009 Oct; 118(4):541-52. PMID: 19529948.
    Citations:    
  16. Nuotio K, Isoviita PM, Saksi J, Ijäs P, Pitkäniemi J, Sonninen R, Soinne L, Saimanen E, Salonen O, Kovanen PT, Kaste M, Lindsberg PJ. Adipophilin expression is increased in symptomatic carotid atherosclerosis: correlation with red blood cells and cholesterol crystals. Stroke. 2007 Jun; 38(6):1791-8. PMID: 17446422.
    Citations:    
  17. Ijäs P, Nuotio K, Saksi J, Soinne L, Saimanen E, Karjalainen-Lindsberg ML, Salonen O, Sarna S, Tuimala J, Kovanen PT, Kaste M, Lindsberg PJ. Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques. Arterioscler Thromb Vasc Biol. 2007 Jan; 27(1):154-60. PMID: 17095719.
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  18. Nuotio K, Mäyränpää MI, Saksi J, Ijas P, Sairanen T, Carpén O, Soinne L, Saimanen E, Salonen O, Lepäntalo M, Kovanen PT, Kaste M, Lindsberg PJ. Endothelial apoptosis does not determine symptom status in carotid artery disease. Cerebrovasc Dis. 2007; 23(1):27-34. PMID: 16968983.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.