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Tarek Hassaan Mouhieddine, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Mouhieddine TH, Hieulle J, Moshier E, Richard S, Richter J, Cho HJ, Parekh S, Barlogie B, Chari A, Jagannath S, Madduri D. Treatment Bridging With a 28-Day Metronomic Therapy (Metro-28) for Relapsed Refractory Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2021 Sep 11. PMID: 34670732.
    Citations:    Fields:    
  2. Van Oekelen O, Gleason CR, Agte S, Srivastava K, Beach KF, Aleman A, Kappes K, Mouhieddine TH, Wang B, Chari A, Cordon-Cardo C, Krammer F, Jagannath S, Simon V, Wajnberg A, Parekh S. Highly variable SARS-CoV-2 spike antibody responses to two doses of COVID-19 RNA vaccination in patients with multiple myeloma. Cancer Cell. 2021 08 09; 39(8):1028-1030. PMID: 34242572.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  3. Adib E, Nassar AH, Akl EW, Abou Alaiwi S, Nuzzo PV, Mouhieddine TH, Sonpavde G, Haddad RI, Mouw KW, Giannakis M, Hodi FS, Shukla SA, Gusev A, Braun DA, Choueiri TK, Kwiatkowski DJ. CDKN2A Alterations and Response to Immunotherapy in Solid Tumors. Clin Cancer Res. 2021 Jul 15; 27(14):4025-4035. PMID: 34074656.
    Citations: 2     Fields:    
  4. Mouhieddine TH, Parekh S, Cho HJ, Richter J, DeCastro A, Shah J, Landesman Y, Chari A, Jagannath S, Madduri D. Selinexor, bortezomib, and dexamethasone (SVD) in heavily treated relapsed refractory multiple myeloma. Ann Hematol. 2020 Oct 02. PMID: 33009581.
    Citations: 1     Fields:    
  5. Wang B, Van Oekelen O, Mouhieddine TH, Del Valle DM, Richter J, Cho HJ, Richard S, Chari A, Gnjatic S, Merad M, Jagannath S, Parekh S, Madduri D. A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward. J Hematol Oncol. 2020 07 14; 13(1):94. PMID: 32664919.
    Citations: 40     Fields:    Translation:HumansCellsPHPublic Health
  6. Wang B, Van Oekelen O, Mouhieddine TH, Del Valle DM, Richter J, Cho HJ, Richard S, Chari A, Gnjatic S, Merad M, Jagannath S, Parekh S, Madduri D. A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward. medRxiv. 2020 Jun 29. PMID: 32577702.
  7. Mouhieddine TH, Sperling AS, Redd R, Park J, Leventhal M, Gibson CJ, Manier S, Nassar AH, Capelletti M, Huynh D, Bustoros M, Sklavenitis-Pistofidis R, Tahri S, Hornburg K, Dumke H, Itani MM, Boehner CJ, Liu CJ, AlDubayan SH, Reardon B, Van Allen EM, Keats JJ, Stewart C, Mehr S, Auclair D, Schlossman RL, Munshi NC, Anderson KC, Steensma DP, Laubach JP, Richardson PG, Ritz J, Ebert BL, Soiffer RJ, Trippa L, Getz G, Neuberg DS, Ghobrial IM. Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant. Nat Commun. 2020 06 12; 11(1):2996. PMID: 32533060.
    Citations: 14     Fields:    Translation:Humans
  8. Lomas OC, Mouhieddine TH, Tahri S, Ghobrial IM. Monoclonal Gammopathy of Undetermined Significance (MGUS)-Not So Asymptomatic after All. Cancers (Basel). 2020 Jun 12; 12(6). PMID: 32545521.
    Citations: 7     
  9. Bustoros M, Sklavenitis-Pistofidis R, Park J, Redd R, Zhitomirsky B, Dunford AJ, Salem K, Tai YT, Anand S, Mouhieddine TH, Chavda SJ, Boehner C, Elagina L, Neuse CJ, Cha J, Rahmat M, Taylor-Weiner A, Van Allen E, Kumar S, Kastritis E, Leshchiner I, Morgan EA, Laubach J, Casneuf T, Richardson P, Munshi NC, Anderson KC, Trippa L, Aguet F, Stewart C, Dimopoulos MA, Yong K, Bergsagel PL, Manier S, Getz G, Ghobrial IM. Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression. J Clin Oncol. 2020 07 20; 38(21):2380-2389. PMID: 32442065.
    Citations: 21     Fields:    Translation:Humans
  10. Zavidij O, Haradhvala NJ, Mouhieddine TH, Sklavenitis-Pistofidis R, Cai S, Reidy M, Rahmat M, Flaifel A, Ferland B, Su NK, Agius MP, Park J, Manier S, Bustoros M, Huynh D, Capelletti M, Berrios B, Liu CJ, He MX, Braggio E, Fonseca R, Maruvka Y, Guerriero JL, Goldman M, van Allen E, McCarroll SA, Azzi J, Getz G, Ghobrial IM. Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma. Nat Cancer. 2020 May; 1(5):493-506. PMID: 33409501.
    Citations: 23     
  11. Abou Alaiwi S, Nassar AH, Xie W, Bakouny Z, Berchuck JE, Braun DA, Baca SC, Nuzzo PV, Flippot R, Mouhieddine TH, Spurr LF, Li YY, Li T, Flaifel A, Steinharter JA, Margolis CA, Vokes NI, Du H, Shukla SA, Cherniack AD, Sonpavde G, Haddad RI, Awad MM, Giannakis M, Hodi FS, Liu XS, Signoretti S, Kadoch C, Freedman ML, Kwiatkowski DJ, Van Allen EM, Choueiri TK. Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors. Cancer Immunol Res. 2020 08; 8(8):1075-1084. PMID: 32321774.
    Citations: 4     Fields:    Translation:Humans
  12. Mouhieddine TH, Ahmad Y, Barlogie B, Jagannath S, Teruya-Feldstein J, Richter J. Increased Muscle CXCR4 Expression in the Setting of Rare Muscle-invasive Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2020 06; 20(6):e341-e344. PMID: 32265150.
    Citations: 1     Fields:    Translation:HumansCells
  13. Mouhieddine TH, Barlogie B, Teruya-Feldstein J. Hemophagocytic relapsed intramedullary plasmacytoma. Int J Hematol. 2020 Jun; 111(6):888-890. PMID: 31900879.
    Citations:    Fields:    Translation:Humans
  14. Mouhieddine TH, Weeks LD, Ghobrial IM. Monoclonal gammopathy of undetermined significance. Blood. 2019 06 06; 133(23):2484-2494. PMID: 31010848.
    Citations: 9     Fields:    Translation:Humans
  15. Araki T, Mouhieddine TH, Tirumani SH, Gujrathi R, Shinagare AB, Ramaiya NH, Jagannathan JP. Focal Liver Uptake on FDG PET/CT Without CT Correlate: Utility of MRI in the Evaluation of Patients With Known Malignancy. AJR Am J Roentgenol. 2019 Jul; 213(1):175-181. PMID: 30995099.
    Citations:    Fields:    
  16. Bahmad HF, Mouhieddine TH, Chalhoub RM, Assi S, Araji T, Chamaa F, Itani MM, Nokkari A, Kobeissy F, Daoud G, Abou-Kheir W. The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma. Oncotarget. 2018 Sep 11; 9(71):33549-33561. PMID: 30323898.
    Citations: 17     Fields:    
  17. Detappe A, Bustoros M, Mouhieddine TH, Ghoroghchian PP. Advancements in Nanomedicine for Multiple Myeloma. Trends Mol Med. 2018 06; 24(6):560-574. PMID: 29773319.
    Citations: 3     Fields:    Translation:HumansAnimals
  18. Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine TH, Manier S, Mishima Y, Murakami N, Bustoros M, Pistofidis RS, Reidy M, Shen YJ, Rahmat M, Lukyanchykov P, Karreci ES, Tsukamoto S, Shi J, Takagi S, Huynh D, Sacco A, Tai YT, Chesi M, Bergsagel PL, Roccaro AM, Azzi J, Ghobrial IM. Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression. J Clin Invest. 2018 06 01; 128(6):2487-2499. PMID: 29558366.
    Citations: 29     Fields:    Translation:AnimalsCells
  19. Tao Z, Muzumdar MD, Detappe A, Huang X, Xu ES, Yu Y, Mouhieddine TH, Song H, Jacks T, Ghoroghchian PP. Differences in Nanoparticle Uptake in Transplanted and Autochthonous Models of Pancreatic Cancer. . 2018 04 11; 18(4):2195-2208. PMID: 29533667.
    Citations: 2     Translation:HumansAnimalsCells
  20. Bustoros M, Mouhieddine TH, Detappe A, Ghobrial IM. Established and Novel Prognostic Biomarkers in Multiple Myeloma. Am Soc Clin Oncol Educ Book. 2017; 37:548-560. PMID: 28561668.
    Citations: 8     Fields:    Translation:Humans
  21. Daoud G, Monzer A, Bahmad H, Chamaa F, Hamdar L, Mouhieddine TH, Shayya S, Eid A, Kobeissy F, Liu YN, Abou-Kheir W. Primary versus castration-resistant prostate cancer: modeling through novel murine prostate cancer cell lines. Oncotarget. 2016 May 17; 7(20):28961-75. PMID: 27036046.
    Citations: 9     Fields:    Translation:AnimalsCells
  22. Zhu R, Yang T, Kobeissy F, Mouhieddine TH, Raad M, Nokkari A, Gold MS, Wang KK, Mechref Y. The Effect of Chronic Methamphetamine Exposure on the Hippocampal and Olfactory Bulb Neuroproteomes of Rats. PLoS One. 2016; 11(4):e0151034. PMID: 27082425.
    Citations:    Fields:    Translation:Animals
  23. Mouhieddine TH, Nokkari A, Itani MM, Chamaa F, Bahmad H, Monzer A, El-Merahbi R, Daoud G, Eid A, Kobeissy FH, Abou-Kheir W. Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells. Front Neurosci. 2015; 9:442. PMID: 26635517.
    Citations: 22     
  24. Nokkari A, Mouhieddine TH, Itani MM, Abou-Kheir W, Daoud G, Zhu R, Mechref Y, Soueid J, Al Hariri M, Mondello S, Jaffa AA, Kobeissy F. Correction: Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment. PLoS One. 2015; 10(8):e0136345. PMID: 26288275.
    Citations:    Fields:    
  25. Nokkari A, Mouhieddine TH, Itani MM, Abou-Kheir W, Daoud G, Zhu R, Mechref Y, Meshref Y, Soueid J, Al Hariri M, Mondello S, Jaffa AA, Kobeissy F. Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment. PLoS One. 2015; 10(6):e0128601. PMID: 26047500.
    Citations: 4     Fields:    Translation:AnimalsCells
  26. Kobeissy FH, Mouhieddine TH, Awwad HO. Traumatic brain injury research woefully ignored. Nature Middle East. 2015.
  27. Mouhieddine TH, Darwish H, Fawaz L, Yamout B, Tamim H, Khoury SJ. Risk factors for multiple sclerosis and associations with anti-EBV antibody titers. Clin Immunol. 2015 May; 158(1):59-66. PMID: 25805657.
    Citations: 6     Fields:    Translation:HumansCells
  28. Mouhieddine TH, El-Houjeiri L, Sabra M, Hayes R, Mondello S. CNS Trauma Biomarkers and Surrogate Endpoints Pipeline from Bench to Bedside: a Translational Perspective. Brain Injury Principles: Molecular, Neuropsychological and Rehabilitation Aspects in Brain Injury Models. 2015.
  29. Mouhieddine TH, Itani MM, Nokkari A, Ren C, Daoud G, Zeidan A, Mondello S, Kobeissy FH. Nanotheragnostic applications for ischemic and hemorrhagic strokes: improved delivery for a better prognosis. Curr Neurol Neurosci Rep. 2015 Jan; 15(1):505. PMID: 25394858.
    Citations: 4     Fields:    Translation:HumansAnimals
  30. Chen WY, Liu SY, Chang YS, Yin JJ, Yeh HL, Mouhieddine TH, Hadadeh O, Abou-Kheir W, Liu YN. MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer. Oncotarget. 2015 Jan 01; 6(1):441-57. PMID: 25436980.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  31. El-Merahbi R, Liu YN, Eid A, Daoud G, Hosry L, Monzer A, Mouhieddine TH, Hamade A, Najjar F, Abou-Kheir W. Berberis libanotica Ehrenb extract shows anti-neoplastic effects on prostate cancer stem/progenitor cells. PLoS One. 2014; 9(11):e112453. PMID: 25380390.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  32. Mouhieddine TH, Kheir WA, Itani M, Nokkari A, Nahas Z. Transcranial Magnetic Stimulation and Deep Brain Stimulation in Neuropsychiatric Disorders: New Dimension of Therapuetic Markers in Psychiatry. Biomarkers of Brain Injury and Neurological Disorders. 2014; 514-565.
  33. Mouhieddine TH, Olleik Z, Itani MM, Kawtharani S, Nassar H, Hassoun R, Houmani Z, El Zein Z, Fakih R, Mortada IK, Mohsen Y, Kanafani Z, Tamim H. Assessing the Lebanese population for their knowledge, attitudes and practices of antibiotic usage. J Infect Public Health. 2015 Jan-Feb; 8(1):20-31. PMID: 25154919.
    Citations: 19     Fields:    Translation:Humans
  34. Kobeissy F, Mouhieddine TH, Nokkari A, Itani M, Mouhieddine M, Zhang Z, Zhu R, Gold MS, Wang KK, Mechref Y. Recent Updates of Drug Abuse Neuroproteomics Studies: Cocaine, Methamphetamine and MDMA. Translational Proteomics. 2014; 3:38–52.
  35. Mouhieddine TH, Kobeissy FH, Itani M, Nokkari A, Wang KK. Stem cells in neuroinjury and neurodegenerative disorders: challenges and future neurotherapeutic prospects. Neural Regen Res. 2014 May 01; 9(9):901-6. PMID: 25206908.
    Citations: 14     
  36. Assi HA, Khoury KE, Mouhieddine TH, Khalil LE, Kanj A, Tawil A, El-Saghir NS. Journal of Cancer Biology and Research. Small Cell Lung Cancer with Metastasis to the Breast: A Case Report and Review of the Literature. 2014; 2(1):1025.
  37. Abou-Kheir W, Mouhieddine TH, Itani MM, Liu YN. Bone metastatic prostate cancer and resistance to tyrosine kinase inhibitors: an intimate relationship between loss of miR-203 and up-regulation of EGFR signaling. RNA & Disease. 2014; 1(1).
  38. Assi HA, Khoury KE, Dbouk H, Khalil LE, Mouhieddine TH, El Saghir NS. Epidemiology and prognosis of breast cancer in young women. J Thorac Dis. 2013 Jun; 5 Suppl 1:S2-8. PMID: 23819024.
    Citations: 98     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.