Harvard Catalyst Profiles

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Roberto De Luca, Ph.D.

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Heinrich-Heine-University, Duesseldorf, GermanyPhD03/2016Molecular Neurophysiology
University “Roma Tre”, Rome, ItalyMSc02/2013Biology, Immunology and Developmental Neuroscience
University “Roma Tre”, Rome, ItalyBSc02/2011Biological Sciences, Microbiology
BCC “Giuseppe Toniolo” MSc degree Award
“Piero Redaelli” MSc degree Award
Travel grant for 10th International Meeting on Rapid Responses to Steroid Hormones (RRSH) 2016
Special Commendation Award in the Young Investigator Awards at the 48th EHRS meeting
Trainee Merit Based Award at the 33rd SRS meeting


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. De Luca R, Nardone S, Grace KP, Venner A, Cristofolini M, Bandaru SS, Sohn LT, Kong D, Mochizuki T, Viberti B, Zhu L, Zito A, Scammell TE, Saper CB, Lowell BB, Fuller PM and Arrigoni E. Orexin neurons inhibit sleep to promote arousal. Nat Commun, in press. 2022.
  2. Chung CC, Huang TY, Chu HR, De Luca R, Candelotti E, Huang CH, Yang YSH, Incerpi S, Pedersen JZ, Lin CY, Huang HM, Lee SY, Li ZL, ChangOu CA, Li WS, Davis PJ, Lin HY, Whang-Peng J, Wang K. Heteronemin and tetrac derivatives suppress non-small cell lung cancer growth via ERK1/2 inhibition. Food Chem Toxicol. 2022 Mar; 161:112850. PMID: 35151786.
    Citations:    Fields:    Translation:HumansCells
  3. Sergeeva OA, Mazur K, Kernder A, Haas HL, De Luca R. Tachykinins amplify the action of capsaicin on central histaminergic neurons. Peptides. 2022 04; 150:170729. PMID: 34958850.
    Citations: 1     Fields:    Translation:AnimalsCells
  4. Cheng TM, Chang WJ, Chu HY, De Luca R, Pedersen JZ, Incerpi S, Li ZL, Shih YJ, Lin HY, Wang K, Whang-Peng J. Nano-Strategies Targeting the Integrin avß3 Network for Cancer Therapy. Cells. 2021 07 03; 10(7). PMID: 34359854.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  5. Candelotti E, De Luca R, Megna R, Maiolo M, De Vito P, Gionfra F, Percario ZA, Borgatti M, Gambari R, Davis PJ, Lin HY, Polticelli F, Persichini T, Colasanti M, Affabris E, Pedersen JZ, Incerpi S. Inhibition by Thyroid Hormones of Cell Migration Activated by IGF-1 and MCP-1 in THP-1 Monocytes: Focus on Signal Transduction Events Proximal to Integrin avß3. Front Cell Dev Biol. 2021; 9:651492. PMID: 33898447.
    Citations: 1     
  6. De Luca R, Davis PJ, Lin HY, Gionfra F, Percario ZA, Affabris E, Pedersen JZ, Marchese C, Trivedi P, Anastasiadou E, Negro R, Incerpi S. Thyroid Hormones Interaction With Immune Response, Inflammation and Non-thyroidal Illness Syndrome. Front Cell Dev Biol. 2020; 8:614030. PMID: 33553149.
    Citations: 9     
  7. Todd WD, Venner A, Anaclet C, Broadhurst RY, De Luca R, Bandaru SS, Issokson L, Hablitz LM, Cravetchi O, Arrigoni E, Campbell JN, Allen CN, Olson DP, Fuller PM. Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations. Nat Commun. 2020 09 02; 11(1):4410. PMID: 32879310.
    Citations: 21     Fields:    Translation:AnimalsCells
  8. Kaur S, De Luca R, Khanday MA, Bandaru SS, Thomas RC, Broadhurst RY, Venner A, Todd WD, Fuller PM, Arrigoni E, Saper CB. Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals. Nat Commun. 2020 06 02; 11(1):2769. PMID: 32488015.
    Citations: 6     Fields:    Translation:AnimalsCells
  9. Venner A, De Luca R, Sohn LT, Bandaru SS, Verstegen AMJ, Arrigoni E, Fuller PM. An Inhibitory Lateral Hypothalamic-Preoptic Circuit Mediates Rapid Arousals from Sleep. Curr Biol. 2019 12 16; 29(24):4155-4168.e5. PMID: 31761703.
    Citations: 11     Fields:    Translation:AnimalsCells
  10. Segal M, Biscans A, Gilles ME, Anastasiadou E, De Luca R, Lim J, Khvorova A, Slack FJ. Hydrophobically Modified let-7b miRNA Enhances Biodistribution to NSCLC and Downregulates HMGA2 In Vivo. Mol Ther Nucleic Acids. 2020 Mar 06; 19:267-277. PMID: 31855835.
    Citations: 15     
  11. Venner A, Mochizuki T, De Luca R, Anaclet C, Scammell TE, Saper CB, Arrigoni E, Fuller PM. Reassessing the Role of Histaminergic Tuberomammillary Neurons in Arousal Control. J Neurosci. 2019 11 06; 39(45):8929-8939. PMID: 31548232.
    Citations: 9     Fields:    Translation:AnimalsCells
  12. De Luca R, Mazur K, Kernder A, Suvorava T, Kojda G, Haas HL, Sergeeva OA. Mechanisms of N-oleoyldopamine activation of central histaminergic neurons. Neuropharmacology. 2018 12; 143:327-338. PMID: 30219501.
    Citations:    Fields:    Translation:AnimalsCells
  13. Anaclet C, De Luca R, Venner A, Malyshevskaya O, Lazarus M, Arrigoni E, Fuller PM. Genetic Activation, Inactivation, and Deletion Reveal a Limited And Nuanced Role for Somatostatin-Containing Basal Forebrain Neurons in Behavioral State Control. J Neurosci. 2018 05 30; 38(22):5168-5181. PMID: 29735555.
    Citations: 8     Fields:    Translation:AnimalsCells
  14. De Luca R, Xie X, Zhao Y, Haas H, Sergeeva O, Lin JS. Activation des neurones histaminergiques et orexinergiques par la testostérone . Médecine du Sommeil . 2018; 15(1):6-7. View Publication.
  15. Sergeeva OA, De Luca R, Mazur K, Chepkova AN, Haas HL, Bauer A. N-oleoyldopamine modulates activity of midbrain dopaminergic neurons through multiple mechanisms. Neuropharmacology. 2017 06; 119:111-122. PMID: 28400256.
    Citations: 4     Fields:    Translation:AnimalsCells
  16. De Luca R, Suvorava T, Yang D, Baumgärtel W, Kojda G, Haas HL, Sergeeva OA. Identification of histaminergic neurons through histamine 3 receptor-mediated autoinhibition. Neuropharmacology. 2016 07; 106:102-15. PMID: 26297536.
    Citations: 5     Fields:    Translation:AnimalsCells
  17. Biamonte F, Latini L, Giorgi FS, Zingariello M, Marino R, De Luca R, D'Ilio S, Majorani C, Petrucci F, Violante N, Senofonte O, Molinari M, Keller F. Associations among exposure to methylmercury, reduced Reelin expression, and gender in the cerebellum of developing mice. Neurotoxicology. 2014 Dec; 45:67-80. PMID: 25305366.
    Citations: 11     Fields:    Translation:AnimalsCells
  18. Kernder A, De Luca R, Yanovsky Y, Haas HL, Sergeeva OA. Acid-sensing hypothalamic neurons controlling arousal. Cell Mol Neurobiol. 2014 Aug; 34(6):777-89. PMID: 24798513.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.