Harvard Catalyst Profiles

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Yuzuru Sasamoto, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Sasamoto Y, Lee CAA, Wilson BJ, Buerger F, Martin G, Mishra A, Kiritoshi S, Tran J, Gonzalez G, Hildebrandt F, Jo VY, Lian CG, Murphy GF, Ksander BR, Frank MH, Frank NY. Limbal BCAM expression identifies a proliferative progenitor population capable of holoclone formation and corneal differentiation. Cell Rep. 2022 08 09; 40(6):111166. PMID: 35947947; PMCID: PMC9480518.
    Citations:    Fields:    Translation:Cells
  2. Yoshinaga Y, Soma T, Azuma S, Maruyama K, Hashikawa Y, Katayama T, Sasamoto Y, Takayanagi H, Hosen N, Shiina T, Ogasawara K, Hayashi R, Nishida K. Long-term survival in non-human primates of stem cell-derived, MHC-unmatched corneal epithelial cell sheets. Stem Cell Reports. 2022 07 12; 17(7):1714-1729. PMID: 35750044; PMCID: PMC9287743.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Sasamoto Y, Lee CAA, Yoshihara M, Martin G, Ksander BR, Frank MH, Frank NY. High expression of SARS-CoV2 viral entry-related proteins in human limbal stem cells. Ocul Surf. 2022 01; 23:197-200. PMID: 34653711; PMCID: PMC8511872.
    Citations: 2     Fields:    Translation:HumansCells
  4. Watanabe S, Hayashi R, Sasamoto Y, Tsujikawa M, Ksander BR, Frank MH, Quantock AJ, Frank NY, Nishida K. Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities. iScience. 2021 Jun 25; 24(6):102688. PMID: 34195566.
    Citations: 1     
  5. Sasamoto Y, Sasamoto N, Tran J, Mishra A, Ksander BR, Frank MH, Frank NY. Investigation of factors associated with ABCB5-positive limbal stem cell isolation yields from human donors. Ocul Surf. 2020 01; 18(1):114-120. PMID: 31655212.
    Citations: 3     Fields:    Translation:HumansCells
  6. Fujimoto S, Hayashi R, Hara S, Sasamoto Y, Harrington J, Tsujikawa M, Nishida K. KLF4 prevents epithelial to mesenchymal transition in human corneal epithelial cells via endogenous TGF-ß2 suppression. Regen Ther. 2019 Dec; 11:249-257. PMID: 31538102; PMCID: PMC6745437.
    Citations: 4     
  7. Sasamoto Y, Ksander BR, Frank MH, Frank NY. Repairing the corneal epithelium using limbal stem cells or alternative cell-based therapies. Expert Opin Biol Ther. 2018 05; 18(5):505-513. PMID: 29471701; PMCID: PMC6317528.
    Citations: 16     Fields:    Translation:HumansCells
  8. Iwama Y, Soma T, Maeda N, Sasamoto Y, Oie Y, Koh S, Nishida K. Factors Limiting the Visual Outcome After Descemet Stripping Automated Endothelial Keratoplasty: Comprehensive Analysis Including the Graft Position and Irregularity. Cornea. 2018 Jan; 37(1):20-27. PMID: 29040117.
    Citations: 1     Fields:    Translation:Humans
  9. Gonzalez G, Sasamoto Y, Ksander BR, Frank MH, Frank NY. Limbal stem cells: identity, developmental origin, and therapeutic potential. Wiley Interdiscip Rev Dev Biol. 2018 03; 7(2). PMID: 29105366.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  10. Yoshihara M, Sasamoto Y, Hayashi R, Ishikawa Y, Tsujikawa M, Hayashizaki Y, Itoh M, Kawaji H, Nishida K. High-resolution promoter map of human limbal epithelial cells cultured with keratinocyte growth factor and rho kinase inhibitor. Sci Rep. 2017 06 06; 7(1):2845. PMID: 28588247.
    Citations: 3     Fields:    Translation:HumansCells
  11. Hayashi R, Ishikawa Y, Katori R, Sasamoto Y, Taniwaki Y, Takayanagi H, Tsujikawa M, Sekiguchi K, Quantock AJ, Nishida K. Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells. Nat Protoc. 2017 04; 12(4):683-696. PMID: 28253236.
    Citations: 33     Fields:    Translation:HumansCells
  12. Hayashi R, Ishikawa Y, Sasamoto Y, Katori R, Nomura N, Ichikawa T, Araki S, Soma T, Kawasaki S, Sekiguchi K, Quantock AJ, Tsujikawa M, Nishida K. Co-ordinated ocular development from human iPS cells and recovery of corneal function. Nature. 2016 Mar 17; 531(7594):376-80. PMID: 26958835.
    Citations: 80     Fields:    Translation:HumansAnimalsCells
  13. Sasamoto Y, Hayashi R, Park SJ, Saito-Adachi M, Suzuki Y, Kawasaki S, Quantock AJ, Nakai K, Tsujikawa M, Nishida K. PAX6 Isoforms, along with Reprogramming Factors, Differentially Regulate the Induction of Cornea-specific Genes. Sci Rep. 2016 Feb 22; 6:20807. PMID: 26899008; PMCID: PMC4761963.
    Citations: 21     Fields:    Translation:HumansCells
  14. Sasamoto Y, Oshima Y, Miki A, Wakabayashi T, Song D, Matsushita K, Hamasaki T, Nishida K. Clinical outcomes and changes in aqueous vascular endothelial growth factor levels after intravitreal bevacizumab for iris neovascularization and neovascular glaucoma: a retrospective two-dose comparative study. J Ocul Pharmacol Ther. 2012 Feb; 28(1):41-8. PMID: 21992534.
    Citations: 6     Fields:    Translation:Humans
  15. Sasamoto Y, Gomi F, Sawa M, Tsujikawa M, Nishida K. Effect of 1-year lutein supplementation on macular pigment optical density and visual function. Graefes Arch Clin Exp Ophthalmol. 2011 Dec; 249(12):1847-54. PMID: 21850440.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  16. Sasamoto Y, Gomi F, Sawa M, Sakaguchi H, Tsujikawa M, Nishida K. Effect of cataract in evaluation of macular pigment optical density by autofluorescence spectrometry. Invest Ophthalmol Vis Sci. 2011 Feb 16; 52(2):927-32. PMID: 21071730.
    Citations: 15     Fields:    Translation:Humans
  17. Gomi F, Sawa M, Wakabayashi T, Sasamoto Y, Suzuki M, Tsujikawa M. Efficacy of intravitreal bevacizumab combined with photodynamic therapy for polypoidal choroidal vasculopathy. Am J Ophthalmol. 2010 Jul; 150(1):48-54.e1. PMID: 20609707.
    Citations: 33     Fields:    Translation:Humans
  18. Sasamoto Y, Gomi F, Sawa M, Tsujikawa M, Hamasaki T. Macular pigment optical density in central serous chorioretinopathy. Invest Ophthalmol Vis Sci. 2010 Oct; 51(10):5219-25. PMID: 20445108.
    Citations: 8     Fields:    Translation:Humans
  19. Namba K, Ogasawara K, Kitaichi N, Morohashi T, Sasamoto Y, Kotake S, Matsuda H, Iwabuchi K, Iwabuchi C, Ohno S, Onoé K. Amelioration of experimental autoimmune uveoretinitis by pretreatment with a pathogenic peptide in liposome and anti-CD40 ligand monoclonal antibody. J Immunol. 2000 Sep 15; 165(6):2962-9. PMID: 10975803.
    Citations: 9     Fields:    Translation:AnimalsCells
  20. Kitaichi N, Matsuda A, Kotake S, Namba K, Tagawa Y, Sasamoto Y, Ogasawara K, Iwabuchi K, Onoé K, Matsuda H, Nishihira J. Inhibition of experimental autoimmune uveoretinitis with anti-macrophage migration inhibitory factor antibodies. Curr Eye Res. 2000 Feb; 20(2):109-14. PMID: 10617911.
    Citations: 5     Fields:    Translation:AnimalsCells
  21. Namba K, Ogasawara K, Kitaichi N, Matsuki N, Takahashi A, Sasamoto Y, Kotake S, Matsuda H, Iwabuchi K, Ohno S, Onoé K. Identification of a peptide inducing experimental autoimmune uveoretinitis (EAU) in H-2Ak-carrying mice. Clin Exp Immunol. 1998 Feb; 111(2):442-9. PMID: 9486417; PMCID: PMC1904926.
    Citations: 5     Fields:    Translation:AnimalsCells
  22. Furudate N, Sasamoto Y, Kotake S, Ogasawara K, Onoé K, Matsuda H. [MHC and non-MHC gene effects on the development of experimental autoimmune uveoretinitis]. Nippon Ganka Gakkai Zasshi. 1995 May; 99(5):537-40. PMID: 7785511.
    Citations:    Fields:    Translation:AnimalsCells
  23. Hirose S, Ogasawara K, Natori T, Sasamoto Y, Ohno S, Matsuda H, Onoé K. Regulation of experimental autoimmune uveitis in rats--separation of MHC and non-MHC gene effects. Clin Exp Immunol. 1991 Dec; 86(3):419-25. PMID: 1747950; PMCID: PMC1554179.
    Citations: 3     Fields:    Translation:AnimalsCellsPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.