Harvard Catalyst Profiles

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Rhea Bhargava, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bhargava R, Li H, Tsokos GC. Pathogenesis of lupus nephritis: the contribution of immune and kidney resident cells. Curr Opin Rheumatol. 2023 Mar 01; 35(2):107-116. PMID: 35797522.
    Citations:    Fields:    
  2. Koga T, Umeda M, Yoshida N, Satyam A, Jha M, Scherlinger M, Bhargava R, Tsokos MG, Sato T, Furukawa K, Endo Y, Fukui S, Iwamoto N, Abiru N, Okita M, Ito M, Kawakami A, Tsokos GC. Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: Dual effect on Th17 cell activation and osteoclastogenesis. Rheumatology (Oxford). 2022 Jul 04. PMID: 35781320.
    Citations:    Fields:    
  3. Hisada R, Yoshida N, Umeda M, Burbano C, Bhargava R, Scherlinger M, Kono M, Kyttaris VC, Krishfield S, Tsokos GC. The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription. Cell Mol Immunol. 2022 06; 19(6):738-750. PMID: 35523941; PMCID: PMC9151795.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Satyam A, Hisada R, Bhargava R, Tsokos MG, Tsokos GC. Intertwined pathways of complement activation command the pathogenesis of lupus nephritis. Transl Res. 2022 07; 245:18-29. PMID: 35296451; PMCID: PMC9167748.
    Citations:    Fields:    Translation:Humans
  5. Jamaly S, Tsokos MG, Bhargava R, Brook OR, Hecht JL, Abdi R, Moulton VR, Satyam A, Tsokos GC. Complement activation and increased expression of Syk, mucin-1 and CaMK4 in kidneys of patients with COVID-19. Clin Immunol. 2021 08; 229:108795. PMID: 34252574.
    Citations: 4     Fields:    Translation:HumansCells
  6. Li H, Tsokos MG, Bhargava R, Adamopoulos IE, Menn-Josephy H, Stillman IE, Rosenstiel P, Jordan J, Tsokos GC. IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation. J Clin Invest. 2021 06 15; 131(12). PMID: 33956666; PMCID: PMC8203450.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  7. Bhargava R, Lehoux S, Maeda K, Tsokos MG, Krishfield S, Ellezian L, Pollak M, Stillman IE, Cummings RD, Tsokos GC. Aberrantly glycosylated IgG elicits pathogenic signaling in podocytes and signifies lupus nephritis. JCI Insight. 2021 05 10; 6(9). PMID: 33784256; PMCID: PMC8262331.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  8. Raines NH, Ganatra S, Nissaisorakarn P, Pandit A, Morales A, Asnani A, Sadrolashrafi M, Maheshwari R, Patel R, Bang V, Shreyder K, Brar S, Singh A, Dani SS, Knapp S, Poyan Mehr A, Brown RS, Zeidel ML, Bhargava R, Schlondorff J, Steinman TI, Mukamal KJ, Parikh SM. Niacinamide May Be Associated with Improved Outcomes in COVID-19-Related Acute Kidney Injury: An Observational Study. Kidney360. 2021 01 28; 2(1):33-41. PMID: 35368823; PMCID: PMC8785722.
    Citations:    Translation:Humans
  9. Bhargava R, Maeda K, Tsokos MG, Pavlakis M, Stillman IE, Tsokos GC. N-glycosylated IgG in patients with kidney transplants increases calcium/calmodulin kinase IV in podocytes and causes injury. Am J Transplant. 2021 01; 21(1):148-160. PMID: 32531122; PMCID: PMC8188503.
    Citations: 3     Fields:    Translation:HumansCells
  10. Bhargava R, Tsokos GC. The immune podocyte. Curr Opin Rheumatol. 2019 03; 31(2):167-174. PMID: 30562182.
    Citations: 12     Fields:    Translation:HumansCells
  11. Ferretti AP, Bhargava R, Dahan S, Tsokos MG, Tsokos GC. Calcium/Calmodulin Kinase IV Controls the Function of Both T Cells and Kidney Resident Cells. Front Immunol. 2018; 9:2113. PMID: 30333818.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  12. Maeda K, Otomo K, Yoshida N, Abu-Asab MS, Ichinose K, Nishino T, Kono M, Ferretti A, Bhargava R, Maruyama S, Bickerton S, Fahmy TM, Tsokos MG, Tsokos GC. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. J Clin Invest. 2018 08 01; 128(8):3445-3459. PMID: 29985166; PMCID: PMC6063476.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  13. Altmann C, Ahuja N, Kiekhaefer CM, Andres Hernando A, Okamura K, Bhargava R, Duplantis J, Kirkbride-Romeo LA, Huckles J, Fox BM, Kahn K, Soranno D, Gil HW, Teitelbaum I, Faubel S. Early peritoneal dialysis reduces lung inflammation in mice with ischemic acute kidney injury. Kidney Int. 2017 08; 92(2):365-376. PMID: 28318621.
    Citations: 8     Fields:    Translation:Animals
  14. Andres-Hernando A, Okamura K, Bhargava R, Kiekhaefer CM, Soranno D, Kirkbride-Romeo LA, Gil HW, Altmann C, Faubel S. Circulating IL-6 upregulates IL-10 production in splenic CD4+ T cells and limits acute kidney injury-induced lung inflammation. Kidney Int. 2017 05; 91(5):1057-1069. PMID: 28214022.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  15. Bhargava R, Abohashem Aly AA, Mertz JI, Mustafa R. Rhabdomyolysis as the first manifestation of human immunodeficiency virus infection. CEN Case Rep. 2016 May; 5(1):48-50. PMID: 28509166.
    Citations: 2     Fields:    
  16. Neyra JA, Rocha NA, Bhargava R, Vaidya OU, Hendricks AR, Rodan AR. Rhabdomyolysis-induced acute kidney injury in a cancer patient exposed to denosumab and abiraterone: a case report. BMC Nephrol. 2015 Jul 30; 16:118. PMID: 26220655.
    Citations: 3     Fields:    Translation:Humans
  17. Andres-Hernando A, Altmann C, Bhargava R, Okamura K, Bacalja J, Hunter B, Ahuja N, Soranno D, Faubel S. Prolonged acute kidney injury exacerbates lung inflammation at 7 days post-acute kidney injury. Physiol Rep. 2014 Jul 01; 2(7). PMID: 25052489.
    Citations: 18     Fields:    
  18. Bhargava R, Altmann CJ, Andres-Hernando A, Webb RG, Okamura K, Yang Y, Falk S, Schmidt EP, Faubel S. Acute lung injury and acute kidney injury are established by four hours in experimental sepsis and are improved with pre, but not post, sepsis administration of TNF-a antibodies. PLoS One. 2013; 8(11):e79037. PMID: 24265742.
    Citations: 38     Fields:    Translation:Animals
  19. Lygizos MI, Yang Y, Altmann CJ, Okamura K, Hernando AA, Perez MJ, Smith LP, Koyanagi DE, Gandjeva A, Bhargava R, Tuder RM, Faubel S, Schmidt EP. Heparanase mediates renal dysfunction during early sepsis in mice. Physiol Rep. 2013 Nov; 1(6):e00153. PMID: 24400155.
    Citations: 39     Fields:    
  20. Bhargava R, Janssen W, Altmann C, Andrés-Hernando A, Okamura K, Vandivier RW, Ahuja N, Faubel S. Intratracheal IL-6 protects against lung inflammation in direct, but not indirect, causes of acute lung injury in mice. PLoS One. 2013; 8(5):e61405. PMID: 23667439.
    Citations: 31     Fields:    Translation:Animals
  21. Ahuja N, Andres-Hernando A, Altmann C, Bhargava R, Bacalja J, Webb RG, He Z, Edelstein CL, Faubel S. Circulating IL-6 mediates lung injury via CXCL1 production after acute kidney injury in mice. Am J Physiol Renal Physiol. 2012 Sep 15; 303(6):F864-72. PMID: 22791336.
    Citations: 50     Fields:    Translation:AnimalsCells
  22. Andres-Hernando A, Dursun B, Altmann C, Ahuja N, He Z, Bhargava R, Edelstein CE, Jani A, Hoke TS, Klein C, Faubel S. Cytokine production increases and cytokine clearance decreases in mice with bilateral nephrectomy. Nephrol Dial Transplant. 2012 Dec; 27(12):4339-47. PMID: 22778179.
    Citations: 28     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.