Harvard Catalyst Profiles

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Zsu-Zsu Chen, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Chen ZZ, Gao Y, Keyes MJ, Deng S, Mi M, Farrell LA, Shen D, Tahir UA, Cruz DE, Ngo D, Benson MD, Robbins JM, Correa A, Wilson JG, Gerszten RE. Protein Markers of Diabetes Discovered in an African American Cohort. Diabetes. 2023 Jan 11. PMID: 36630488.
    Citations:    Fields:    
  2. Chen ZZ, Pacheco JA, Gao Y, Deng S, Peterson B, Shi X, Zheng S, Tahir UA, Katz DH, Cruz DE, Ngo D, Benson MD, Robbins JM, Guo X, Del Rocio Sevilla Gonzalez M, Manning A, Correa A, Meigs JB, Taylor KD, Rich SS, Goodarzi MO, Rotter JI, Wilson JG, Clish CB, Gerszten RE. Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans. Diabetes. 2022 11 01; 71(11):2426-2437. PMID: 35998269; PMCID: PMC9630088.
    Citations:    Fields:    Translation:Humans
  3. Pan XF, Chen ZZ, Wang TJ, Shu X, Cai H, Cai Q, Clish CB, Shi X, Zheng W, Gerszten RE, Shu XO, Yu D. Plasma metabolomic signatures of obesity and risk of type 2 diabetes. Obesity (Silver Spring). 2022 11; 30(11):2294-2306. PMID: 36161775; PMCID: PMC9633360.
    Citations:    Fields:    Translation:Humans
  4. Tahir UA, Katz DH, Avila-Pachecho J, Bick AG, Pampana A, Robbins JM, Yu Z, Chen ZZ, Benson MD, Cruz DE, Ngo D, Deng S, Shi X, Zheng S, Eisman AS, Farrell L, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Ruberg FL, Blaner WS, Jain D, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB, Natarajan P, Gerszten RE. Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nat Commun. 2022 08 22; 13(1):4923. PMID: 35995766; PMCID: PMC9395431.
    Citations:    Fields:    Translation:Humans
  5. Katz DH, Robbins JM, Deng S, Tahir UA, Bick AG, Pampana A, Yu Z, Ngo D, Benson MD, Chen ZZ, Cruz DE, Shen D, Gao Y, Bouchard C, Sarzynski MA, Correa A, Natarajan P, Wilson JG, Gerszten RE. Proteomic profiling platforms head to head: Leveraging genetics and clinical traits to compare aptamer- and antibody-based methods. Sci Adv. 2022 08 19; 8(33):eabm5164. PMID: 35984888; PMCID: PMC9390994.
    Citations: 3     Fields:    Translation:Humans
  6. Majety P, Groysman A, Erlikh N, Chen ZZ, Westcott GP. Predictors of Mortality in Hypercalcemia of Advanced Chronic Liver Disease. Endocr Pract. 2022 Oct; 28(10):1062-1068. PMID: 35868607.
    Citations:    Fields:    
  7. Liu J, Chen ZZ, Patel J, Asnani A. Understanding Myocardial Metabolism in the Context of Cardio-Oncology. Heart Fail Clin. 2022 Jul; 18(3):415-424. PMID: 35718416.
    Citations:    Fields:    Translation:Humans
  8. Haslam DE, Li J, Dillon ST, Gu X, Cao Y, Zeleznik OA, Sasamoto N, Zhang X, Eliassen AH, Liang L, Stampfer MJ, Mora S, Chen ZZ, Terry KL, Gerszten RE, Hu FB, Chan AT, Libermann TA, Bhupathiraju SN. Stability and reproducibility of proteomic profiles in epidemiological studies: comparing the Olink and SOMAscan platforms. Proteomics. 2022 07; 22(13-14):e2100170. PMID: 35598103.
    Citations:    Fields:    Translation:Humans
  9. Cruz DE, Tahir UA, Hu J, Ngo D, Chen ZZ, Robbins JM, Katz D, Balasubramanian R, Peterson B, Deng S, Benson MD, Shi X, Dailey L, Gao Y, Correa A, Wang TJ, Clish CB, Rexrode KM, Wilson JG, Gerszten RE. Metabolomic Analysis of Coronary Heart Disease in an African American Cohort From the Jackson Heart Study. JAMA Cardiol. 2022 02 01; 7(2):184-194. PMID: 34851361; PMCID: PMC8637385.
    Citations:    Fields:    Translation:Humans
  10. Katz DH, Tahir UA, Bick AG, Pampana A, Ngo D, Benson MD, Yu Z, Robbins JM, Chen ZZ, Cruz DE, Deng S, Farrell L, Sinha S, Schmaier AA, Shen D, Gao Y, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Ida Chen YD, Manichaikul AW, Jain D, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Natarajan P, Gerszten RE. Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease. Circulation. 2022 02; 145(5):357-370. PMID: 34814699; PMCID: PMC9158509.
    Citations: 4     Fields:    Translation:Humans
  11. Rodgers M, Migdal AL, Rodríguez TG, Chen ZZ, Nath AK, Gerszten RE, Kasid N, Toschi E, Tripaldi J, Heineman B, Phan M, Ngo L, Maratos-Flier E, Dushay J. Weight Loss Outcomes Among Early High Responders to Exenatide Treatment: A Randomized, Placebo Controlled Study in Overweight and Obese Women. Front Endocrinol (Lausanne). 2021; 12:742873. PMID: 34867786; PMCID: PMC8635796.
    Citations:    Fields:    Translation:Humans
  12. Goldberg RB, Tripputi MT, Boyko EJ, Budoff M, Chen ZZ, Clark JM, Dabelea DM, Edelstein SL, Gerszten RE, Horton E, Mather KJ, Perreault L, Temprosa M, Wallia A, Watson K, Irfan Z. Hepatic Fat in Participants With and Without Incident Diabetes in the Diabetes Prevention Program Outcome Study. J Clin Endocrinol Metab. 2021 10 21; 106(11):e4746-e4765. PMID: 33705543; PMCID: PMC8530730.
    Citations:    Fields:    Translation:Humans
  13. Katz DH, Tahir UA, Ngo D, Benson MD, Gao Y, Shi X, Nayor M, Keyes MJ, Larson MG, Hall ME, Correa A, Sinha S, Shen D, Herzig M, Yang Q, Robbins JM, Chen ZZ, Cruz DE, Peterson B, Vasan RS, Wang TJ, Wilson JG, Gerszten RE. Multiomic Profiling in Black and White Populations Reveals Novel Candidate Pathways in Left Ventricular Hypertrophy and Incident Heart Failure Specific to Black Adults. Circ Genom Precis Med. 2021 06; 14(3):e003191. PMID: 34019435; PMCID: PMC8497179.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  14. Rebholz CM, Gao Y, Talegawkar S, Tucker KL, Colantonio LD, Muntner P, Ngo D, Chen ZZ, Cruz D, Katz DH, Tahir UA, Clish C, Gerszten RE, Wilson JG. Metabolomic Markers of Southern Dietary Patterns in the Jackson Heart Study. Mol Nutr Food Res. 2021 04; 65(8):e2000796. PMID: 33629508; PMCID: PMC8192080.
    Citations: 1     Fields:    Translation:HumansAnimals
  15. Ngo D, Benson MD, Long JZ, Chen ZZ, Wang R, Nath AK, Keyes MJ, Shen D, Sinha S, Kuhn E, Morningstar JE, Shi X, Peterson BD, Chan C, Katz DH, Tahir UA, Farrell LA, Melander O, Mosley JD, Carr SA, Vasan RS, Larson MG, Smith JG, Wang TJ, Yang Q, Gerszten RE. Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk. JCI Insight. 2021 03 08; 6(5). PMID: 33591955; PMCID: PMC8021115.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  16. Tahir UA, Katz DH, Zhao T, Ngo D, Cruz DE, Robbins JM, Chen ZZ, Peterson B, Benson MD, Shi X, Dailey L, Andersson C, Vasan RS, Gao Y, Shen C, Correa A, Hall ME, Wang TJ, Clish CB, Wilson JG, Gerszten RE. Metabolomic Profiles and Heart Failure Risk in Black Adults: Insights From the Jackson Heart Study. Circ Heart Fail. 2021 01; 14(1):e007275. PMID: 33464957; PMCID: PMC9158510.
    Citations: 7     Fields:    Translation:HumansCells
  17. Katz DH, Tahir UA, Ngo D, Benson MD, Bick AG, Pampana A, Gao Y, Keyes MJ, Correa A, Sinha S, Shen D, Yang Q, Robbins JM, Chen ZZ, Cruz DE, Peterson B, Natarajan P, Vasan RS, Smith G, Wang TJ, Gerszten RE. Proteomic Profiling in Biracial Cohorts Implicates DC-SIGN as a Mediator of Genetic Risk in COVID-19. medRxiv. 2020 Jun 11. PMID: 32577670; PMCID: PMC7302224.
    Citations: 1     
  18. Chen ZZ, Gerszten RE. Metabolomics and Proteomics in Type 2 Diabetes. Circ Res. 2020 05 22; 126(11):1613-1627. PMID: 32437301.
    Citations: 12     Fields:    Translation:HumansAnimals
  19. Nath AK, Ma J, Chen ZZ, Li Z, Vitery MDC, Kelley ML, Peterson RT, Gerszten RE, Yeh JJ. Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish. FASEB J. 2020 01; 34(1):1546-1557. PMID: 31914600.
    Citations: 5     Fields:    Translation:AnimalsCells
  20. Chen ZZ, Liu J, Morningstar J, Heckman-Stoddard BM, Lee CG, Dagogo-Jack S, Ferguson JF, Hamman RF, Knowler WC, Mather KJ, Perreault L, Florez JC, Wang TJ, Clish C, Temprosa M, Gerszten RE. Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program. Diabetes. 2019 12; 68(12):2337-2349. PMID: 31582408; PMCID: PMC6868469.
    Citations: 10     Fields:    Translation:Humans
  21. Lin X, Parisiadou L, Gu XL, Wang L, Shim H, Sun L, Xie C, Long CX, Yang WJ, Ding J, Chen ZZ, Gallant PE, Tao-Cheng JH, Rudow G, Troncoso JC, Liu Z, Li Z, Cai H. Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron. 2009 Dec 24; 64(6):807-27. PMID: 20064389; PMCID: PMC2807409.
    Citations: 262     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.