Harvard Catalyst Profiles

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Xiangkun Han, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hou S, Zhou S, Qin Z, Yang L, Han X, Yao S, Ji H. Evidence, Mechanism, and Clinical Relevance of the Transdifferentiation from Lung Adenocarcinoma to Squamous Cell Carcinoma. Am J Pathol. 2017 May; 187(5):954-962. PMID: 28284717.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  2. Xue Y, Hou S, Ji H, Han X. Evolution from genetics to phenotype: reinterpretation of NSCLC plasticity, heterogeneity, and drug resistance. Protein Cell. 2017 03; 8(3):178-190. PMID: 27757846.
    Citations: 1     Fields:    Translation:Humans
  3. Li F, Fang Z, Zhang J, Li C, Liu H, Xia J, Zhu H, Guo C, Qin Z, Li F, Han X, Wang Y, Feng Y, Wang Y, Zhang W, Wang Z, Jin Y, Sun Y, Wei W, Zeng R, Chen H, Ji H. Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma. Cell Res. 2016 Oct; 26(10):1149-1164. PMID: 27670699.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  4. Hou S, Han X, Ji H. Squamous Transition of Lung Adenocarcinoma and Drug Resistance. Trends Cancer. 2016 09; 2(9):463-466. PMID: 28741476.
    Citations: 4     Fields:    Translation:HumansAnimals
  5. Zhang W, Gao Y, Li F, Tong X, Ren Y, Han X, Yao S, Long F, Yang Z, Fan H, Zhang L, Ji H. YAP promotes malignant progression of Lkb1-deficient lung adenocarcinoma through downstream regulation of survivin. Cancer Res. 2015 Nov 01; 75(21):4450-7. PMID: 26363011.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  6. Li F, Han X, Li F, Wang R, Wang H, Gao Y, Wang X, Fang Z, Zhang W, Yao S, Tong X, Wang Y, Feng Y, Sun Y, Li Y, Wong KK, Zhai Q, Chen H, Ji H. LKB1 Inactivation Elicits a Redox Imbalance to Modulate Non-small Cell Lung Cancer Plasticity and Therapeutic Response. Cancer Cell. 2015 May 11; 27(5):698-711. PMID: 25936644.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  7. Gao Y, Zhang W, Han X, Li F, Wang X, Wang R, Fang Z, Tong X, Yao S, Li F, Feng Y, Sun Y, Hou Y, Yang Z, Guan K, Chen H, Zhang L, Ji H. YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression. Nat Commun. 2014 Aug 13; 5:4629. PMID: 25115923.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  8. Fang R, Zheng C, Sun Y, Han X, Gao B, Li C, Liu H, Wong KK, Liu XY, Chen H, Ji H. Integrative genomic analysis reveals a high frequency of LKB1 genetic alteration in Chinese lung adenocarcinomas. J Thorac Oncol. 2014 Feb; 9(2):254-8. PMID: 24419424.
    Citations: 5     Fields:    Translation:Humans
  9. Zhang W, Gao Y, Li P, Shi Z, Guo T, Li F, Han X, Feng Y, Zheng C, Wang Z, Li F, Chen H, Zhou Z, Zhang L, Ji H. VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex. Cell Res. 2014 Mar; 24(3):331-43. PMID: 24458094.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  10. Han X, Li F, Fang Z, Gao Y, Li F, Fang R, Yao S, Sun Y, Li L, Zhang W, Ma H, Xiao Q, Ge G, Fang J, Wang H, Zhang L, Wong KK, Chen H, Hou Y, Ji H. Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma. Nat Commun. 2014; 5:3261. PMID: 24531128.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  11. Li F, Feng Y, Fang R, Fang Z, Xia J, Han X, Liu XY, Chen H, Liu H, Ji H. Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers. Cell Res. 2012 May; 22(5):928-31. PMID: 22349463.
    Citations: 25     Fields:    Translation:Humans
  12. Li C, Sun Y, Fang R, Han X, Luo X, Wang R, Pan Y, Hu H, Zhang Y, Pao W, Shen L, Ji H, Chen H. Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains. J Thorac Oncol. 2012 Jan; 7(1):85-9. PMID: 22071781.
    Citations: 20     Fields:    Translation:Humans
  13. Li C, Fang R, Sun Y, Han X, Li F, Gao B, Iafrate AJ, Liu XY, Pao W, Chen H, Ji H. Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers. PLoS One. 2011; 6(11):e28204. PMID: 22140546.
    Citations: 65     Fields:    Translation:HumansCells
  14. Li C, Sun Y, Fang Z, Han X, Fang R, Zhang Y, Pan Y, Zhang W, Ren Y, Ji H, Chen H. Comprehensive analysis of epidermal growth factor receptor gene status in lung adenocarcinoma. J Thorac Oncol. 2011 Jun; 6(6):1016-21. PMID: 21532505.
    Citations: 4     Fields:    Translation:Humans
  15. Gao Y, Xiao Q, Ma H, Li L, Liu J, Feng Y, Fang Z, Wu J, Han X, Zhang J, Sun Y, Wu G, Padera R, Chen H, Wong KK, Ge G, Ji H. LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):18892-7. PMID: 20956321.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  16. Sun Y, Ren Y, Fang Z, Li C, Fang R, Gao B, Han X, Tian W, Pao W, Chen H, Ji H. Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases. J Clin Oncol. 2010 Oct 20; 28(30):4616-20. PMID: 20855837.
    Citations: 114     Fields:    Translation:Humans
  17. Gao B, Sun Y, Zhang J, Ren Y, Fang R, Han X, Shen L, Liu XY, Pao W, Chen H, Ji H. Spectrum of LKB1, EGFR, and KRAS mutations in chinese lung adenocarcinomas. J Thorac Oncol. 2010 Aug; 5(8):1130-5. PMID: 20559149.
    Citations: 30     Fields:    Translation:Humans
  18. Han X, Zhangli L, Li M, Bao H, Hei N, Chen Q. Ultrastructure of anterior uterus of the oviduct and the stored sperm in female soft-shelled turtle, Trionyx sinensis. Anat Rec (Hoboken). 2008 Mar; 291(3):335-51. PMID: 18231967.
    Citations: 2     Fields:    Translation:AnimalsCells
  19. Xiangkun H, Li Z, Meiying L, Huijun B, Nainan H, Qiusheng C. Seasonal changes of sperm storage and correlative structures in male and female soft-shelled turtles, Trionyx sinensis. Anim Reprod Sci. 2008 Nov; 108(3-4):435-45. PMID: 17997057.
    Citations: 2     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.