Harvard Catalyst Profiles

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Danielle Sara Bitterman, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chaunzwa TL, Del Rey MQ, Bitterman DS. Clinical Informatics Approaches to Understand and Address Cancer Disparities. Yearb Med Inform. 2022 Aug; 31(1):121-130. PMID: 36463869; PMCID: PMC9719762.
    Citations:    Fields:    Translation:Humans
  2. Peterson JS, Plana D, Bitterman DS, Johnson SB, Aerts HJWL, Kann BH. Growth in eligibility criteria content and failure to accrue among National Cancer Institute (NCI)-affiliated clinical trials. Cancer Med. 2023 02; 12(4):4715-4724. PMID: 36398619; PMCID: PMC9972031.
    Citations: 1     Fields:    Translation:Humans
  3. Hosny A, Bitterman DS, Guthier CV, Qian JM, Roberts H, Perni S, Saraf A, Peng LC, Pashtan I, Ye Z, Kann BH, Kozono DE, Christiani D, Catalano PJ, Aerts HJWL, Mak RH. Clinical validation of deep learning algorithms for radiotherapy targeting of non-small-cell lung cancer: an observational study. Lancet Digit Health. 2022 09; 4(9):e657-e666. PMID: 36028289; PMCID: PMC9435511.
    Citations:    Fields:    Translation:Humans
  4. Ding X, Barnett M, Mehrotra A, Tuot DS, Bitterman DS, Miller TA. Classifying unstructured electronic consult messages to understand primary care physician specialty information needs. J Am Med Inform Assoc. 2022 08 16; 29(9):1607-1617. PMID: 35751571; PMCID: PMC9382391.
    Citations:    Fields:    Translation:Humans
  5. Lamba N, Bitterman DS. An Intramedullary Enigma. JAMA Oncol. 2022 05 01; 8(5):770-771. PMID: 35357409.
    Citations:    Fields:    Translation:Humans
  6. Tjong MC, Bitterman DS, Brantley K, Nohria A, Hoffmann U, Atkins KM, Mak RH. Major adverse cardiac event risk prediction model incorporating baseline Cardiac disease, Hypertension, and Logarithmic Left anterior descending coronary artery radiation dose in lung cancer (CHyLL). Radiother Oncol. 2022 04; 169:105-113. PMID: 35182687.
    Citations:    Fields:    Translation:Humans
  7. Atkins KM, Weiss J, Zeleznik R, Bitterman DS, Chaunzwa TL, Huynh E, Guthier C, Kozono DE, Lewis JH, Tamarappoo BK, Nohria A, Hoffmann U, Aerts HJWL, Mak RH. Elevated Coronary Artery Calcium Quantified by a Validated Deep Learning Model From Lung Cancer Radiotherapy Planning Scans Predicts Mortality. JCO Clin Cancer Inform. 2022 01; 6:e2100095. PMID: 35084935.
    Citations: 2     Fields:    Translation:Humans
  8. Kim E, Bitterman DS, Kann BH, Mak RH, Moreno AC, Upadhyay VA, Warner JL, Zhang HM. Hidden in Plain Sight: Clinical Informaticians are the Oncology Subspecialists You Did Not Know You Needed. Clin Oncol (R Coll Radiol). 2022 02; 34(2):135-140. PMID: 34887151; PMCID: PMC8792333.
    Citations: 1     Fields:    Translation:Humans
  9. Perni S, Bitterman D, Ryan J, Silver JK, Mitchell E, Christensen S, Daniels M, Bloom M, Hochberg E, Ryan D, Haas-Kogan D, Loeffler JS, Tarbell NJ, Parikh AR, Wo J. Gender, Productivity, and Philanthropic Fundraising in Academic Oncology. J Natl Compr Canc Netw. 2021 12; 19(12):1401-1406. PMID: 34902830.
    Citations: 1     Fields:    Translation:Humans
  10. Bitterman DS, Selesnick P, Bredfeldt J, Williams CL, Guthier C, Huynh E, Kozono DE, Lewis JH, Cormack RA, Carpenter CM, Mak RH, Atkins KM. Dosimetric Planning Tradeoffs to Reduce Heart Dose Using Machine Learning-Guided Decision Support Software in Patients with Lung Cancer. Int J Radiat Oncol Biol Phys. 2022 03 15; 112(4):996-1003. PMID: 34774998.
    Citations: 1     Fields:    Translation:Humans
  11. Bitterman DS, Chen MH, Wu J, Renshaw AA, Loffredo M, Kantoff PW, Small EJ, D'Amico AV. Prostate-specific antigen nadir and testosterone level at prostate-specific antigen failure following radiation and androgen suppression therapy for unfavorable-risk prostate cancer and the risk of all-cause and prostate cancer-specific mortality. Cancer. 2021 08 01; 127(15):2623-2630. PMID: 33823065; PMCID: PMC9436009.
    Citations: 1     Fields:    Translation:Humans
  12. Atkins KM, Bitterman DS, Chaunzwa TL, Kozono DE, Baldini EH, Aerts HJWL, Tamarappoo BK, Hoffmann U, Nohria A, Mak RH. Mean Heart Dose Is an Inadequate Surrogate for Left Anterior Descending Coronary Artery Dose and the Risk of Major Adverse Cardiac Events in Lung Cancer Radiation Therapy. Int J Radiat Oncol Biol Phys. 2021 08 01; 110(5):1473-1479. PMID: 33713743.
    Citations: 4     Fields:    Translation:Humans
  13. Zeleznik R, Weiss J, Taron J, Guthier C, Bitterman DS, Hancox C, Kann BH, Kim DW, Punglia RS, Bredfeldt J, Foldyna B, Eslami P, Lu MT, Hoffmann U, Mak R, Aerts HJWL. Deep-learning system to improve the quality and efficiency of volumetric heart segmentation for breast cancer. NPJ Digit Med. 2021 Mar 05; 4(1):43. PMID: 33674717.
    Citations: 2     
  14. Bitterman DS, Miller TA, Mak RH, Savova GK. Clinical Natural Language Processing for Radiation Oncology: A Review and Practical Primer. Int J Radiat Oncol Biol Phys. 2021 07 01; 110(3):641-655. PMID: 33545300.
    Citations: 5     Fields:    Translation:Humans
  15. Atkins KM, Chaunzwa TL, Lamba N, Bitterman DS, Rawal B, Bredfeldt J, Williams CL, Kozono DE, Baldini EH, Nohria A, Hoffmann U, Aerts HJWL, Mak RH. Association of Left Anterior Descending Coronary Artery Radiation Dose With Major Adverse Cardiac Events and Mortality in Patients With Non-Small Cell Lung Cancer. JAMA Oncol. 2021 Feb 01; 7(2):206-219. PMID: 33331883; PMCID: PMC7747040.
    Citations: 24     Fields:    Translation:Humans
  16. Atkins KM, Bitterman DS, Chaunzwa TL, Williams CL, Rahman R, Kozono DE, Baldini EH, Aerts HJWL, Tamarappoo BK, Hoffmann U, Nohria A, Mak RH. Statin Use, Heart Radiation Dose, and Survival in Locally Advanced Lung Cancer. Pract Radiat Oncol. 2021 Sep-Oct; 11(5):e459-e467. PMID: 33476841.
    Citations: 4     Fields:    Translation:Humans
  17. Burns ZT, Bitterman DS, Perni S, Boyle PJ, Guss CE, Haas-Kogan DA, Liu KX. Clinical Characteristics, Experiences, and Outcomes of Transgender Patients With Cancer. JAMA Oncol. 2021 Jan 01; 7(1):e205671. PMID: 33180096; PMCID: PMC7821024.
    Citations: 4     Fields:    Translation:Humans
  18. Jhawar SR, Palmer JD, Wang SJ, Bitterman D, Klamer B, Huynh-Le M, Chung C, Ohri N, Stover DG, Lustberg MB, Mishra S, Warner J, Jabbour S, Goyal S. The COVID-19 & Cancer Consortium (CCC19) and Opportunities for Radiation Oncology. Adv Radiat Oncol. 2021 Jan-Feb; 6(1):100614. PMID: 33521393.
    Citations: 1     
  19. Bitterman DS, Aerts HJWL, Mak RH. Approaching autonomy in medical artificial intelligence. Lancet Digit Health. 2020 09; 2(9):e447-e449. PMID: 33328110.
    Citations: 10     Fields:    Translation:Humans
  20. Bitterman DS, Bona K, Laurie F, Kao PC, Terezakis SA, London WB, Haas-Kogan DA. Race Disparities in Proton Radiotherapy Use for Cancer Treatment in Patients Enrolled in Children's Oncology Group Trials. JAMA Oncol. 2020 09 01; 6(9):1465-1468. PMID: 32910158; PMCID: PMC7411938.
    Citations: 9     Fields:    Translation:Humans
  21. Bitterman DS, Winter KA, Hong TS, Fuchs CS, Regine WF, Abrams RA, Safran H, Hoffman JP, Benson AB, Kasunic T, Mulcahy M, Strauss JF, DiPetrillo T, Stella PJ, Chen Y, Plastaras JP, Crane CH. Impact of Diabetes and Insulin Use on Prognosis in Patients With Resected Pancreatic Cancer: An Ancillary Analysis of NRG Oncology RTOG 9704. Int J Radiat Oncol Biol Phys. 2021 01 01; 109(1):201-211. PMID: 32858111.
    Citations: 3     Fields:    Translation:Humans
  22. Huynh E, Hosny A, Guthier C, Bitterman DS, Petit SF, Haas-Kogan DA, Kann B, Aerts HJWL, Mak RH. Artificial intelligence in radiation oncology. Nat Rev Clin Oncol. 2020 12; 17(12):771-781. PMID: 32843739.
    Citations: 48     Fields:    Translation:Humans
  23. Bitterman DS, Bona K, Laurie F, Kao PC, Terezakis SA, London WB, Haas-Kogan DA. Race Disparities in Proton Radiotherapy Use for Cancer Treatment in Patients Enrolled in Children's Oncology Group Trials. JAMA Oncol. 2020 Aug 06. PMID: 32761120.
    Citations:    Fields:    
  24. Bitterman DS, Cagney DN, Singer LL, Nguyen PL, Catalano PJ, Mak RH. Master Protocol Trial Design for Efficient and Rational Evaluation of Novel Therapeutic Oncology Devices. J Natl Cancer Inst. 2020 03 01; 112(3):229-237. PMID: 31504680.
    Citations: 8     Fields:    Translation:Humans
  25. Bitterman DS, Edgington SK, Kilcoyne A, Kim DW, Eyler CE, Qadan M, Ferrone CR, Tanabe KK, Goyal L, Zhu AX, Wo JY, Hong TS. Palliative External Beam Radiation Therapy for Hepatocellular Carcinoma With Right Atrial Tumor Thrombus. Pract Radiat Oncol. 2020 May - Jun; 10(3):e183-e187. PMID: 31931178.
    Citations: 2     Fields:    Translation:Humans
  26. Bitterman DS, MacDonald SM, Yock TI, Tarbell NJ, Wright KD, Chi SN, Marcus KJ, Haas-Kogan DA. Revisiting the Role of Radiation Therapy for Pediatric Low-Grade Glioma. J Clin Oncol. 2019 12 10; 37(35):3335-3339. PMID: 31498029; PMCID: PMC9798905.
    Citations: 9     Fields:    Translation:Humans
  27. Savova GK, Danciu I, Alamudun F, Miller T, Lin C, Bitterman DS, Tourassi G, Warner JL. Use of Natural Language Processing to Extract Clinical Cancer Phenotypes from Electronic Medical Records. Cancer Res. 2019 11 01; 79(21):5463-5470. PMID: 31395609.
    Citations: 29     Fields:    Translation:Humans
  28. Bitterman DS, Chi SN, Haas-Kogan DA. A Central Role of Radiation Therapy in Central Nervous System Germinoma. Int J Radiat Oncol Biol Phys. 2019 08 01; 104(5):970-971. PMID: 31327428.
    Citations:    Fields:    Translation:Humans
  29. Bitterman DS, Sanford NN, Niemierko A, Mahal BA, Qadan M, Ganguli S, Blaszkowsky LS, Zhu AX, Hong TS, Devlin PM, Goyal L, Wo JY. Patterns of Care and Outcomes of Definitive External Beam Radiotherapy and Radioembolization for Localized Hepatocellular Carcinoma: A Propensity Score-adjusted Analysis. Am J Clin Oncol. 2019 07; 42(7):564-572. PMID: 31166209.
    Citations: 1     Fields:    Translation:Humans
  30. Atkins KM, Rawal B, Chaunzwa TL, Lamba N, Bitterman DS, Williams CL, Kozono DE, Baldini EH, Chen AB, Nguyen PL, D'Amico AV, Nohria A, Hoffmann U, Aerts HJWL, Mak RH. Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients With Lung Cancer. J Am Coll Cardiol. 2019 06 18; 73(23):2976-2987. PMID: 31196455.
    Citations: 68     Fields:    Translation:HumansPHPublic Health
  31. Burns ZT, Bitterman DS, Liu KX, Terezakis SA, Neira PM, Haas-Kogan DA. Towards a standard of care in oncology for transgender patients. Lancet Oncol. 2019 03; 20(3):331-333. PMID: 30842045.
    Citations: 3     Fields:    Translation:Humans
  32. Holliday EB, Siker M, Chapman CH, Jagsi R, Bitterman DS, Ahmed AA, Winkfield K, Kelly M, Tarbell NJ, Deville C. Achieving gender equity in the radiation oncology physician workforce. Adv Radiat Oncol. 2018 Oct-Dec; 3(4):478-483. PMID: 30370345; PMCID: PMC6200884.
    Citations: 19     
  33. Chadi SA, Malcomson L, Ensor J, Riley RD, Vaccaro CA, Rossi GL, Daniels IR, Smart NJ, Osborne ME, Beets GL, Maas M, Bitterman DS, Du K, Gollins S, Sun Myint A, Smith FM, Saunders MP, Scott N, O'Dwyer ST, de Castro Araujo RO, Valadao M, Lopes A, Hsiao CW, Lai CL, Smith RK, Paulson EC, Appelt A, Jakobsen A, Wexner SD, Habr-Gama A, Sao Julião G, Perez R, Renehan AG. Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis. Lancet Gastroenterol Hepatol. 2018 12; 3(12):825-836. PMID: 30318451.
    Citations: 31     Fields:    Translation:Humans
  34. Bitterman DS, Zei PC, Mak RH. Radiation Safety and Cardiovascular Implantable Electronic Devices. Int J Radiat Oncol Biol Phys. 2018 10 01; 102(2):243-246. PMID: 30191855.
    Citations: 1     Fields:    Translation:Humans
  35. Bhatla T, Dandekar S, Lu BY, Wang J, Han E, Bitterman D, Jones CL, Evensen NA, Magid M, Meyer JA, Carroll WL. Genomic Characterization of Poorly Differentiated Neuroendocrine Carcinoma in a Pediatric Patient. J Pediatr Hematol Oncol. 2016 Jan; 38(1):e21-5. PMID: 26558807; PMCID: PMC4681625.
    Citations: 3     Fields:    Translation:Humans
  36. Bitterman DS, Resende Salgado L, Moore HG, Sanfilippo NJ, Gu P, Hatzaras I, Du KL. Predictors of Complete Response and Disease Recurrence Following Chemoradiation for Rectal Cancer. Front Oncol. 2015; 5:286. PMID: 26734570; PMCID: PMC4686647.
    Citations: 22     
  37. Grew D, Bitterman D, Leichman CG, Leichman L, Sanfilippo N, Moore HG, Du K. HIV Infection Is Associated With Poor Outcomes for Patients With Anal Cancer in the Highly Active Antiretroviral Therapy Era. Dis Colon Rectum. 2015 Dec; 58(12):1130-6. PMID: 26544809.
    Citations: 12     Fields:    Translation:Humans
  38. Bitterman DS, Grew D, Gu P, Cohen RF, Sanfilippo NJ, Leichman CG, Leichman LP, Moore HG, Gold HT, Du KL. Comparison of anal cancer outcomes in public and private hospital patients treated at a single radiation oncology center. J Gastrointest Oncol. 2015 Oct; 6(5):524-33. PMID: 26487947; PMCID: PMC4570920.
    Citations: 4     
  39. Jones CL, Gearheart CM, Fosmire S, Delgado-Martin C, Evensen NA, Bride K, Waanders AJ, Pais F, Wang J, Bhatla T, Bitterman DS, de Rijk SR, Bourgeois W, Dandekar S, Park E, Burleson TM, Madhusoodhan PP, Teachey DT, Raetz EA, Hermiston ML, Müschen M, Loh ML, Hunger SP, Zhang J, Garabedian MJ, Porter CC, Carroll WL. MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia. Blood. 2015 Nov 05; 126(19):2202-12. PMID: 26324703; PMCID: PMC4635116.
    Citations: 51     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  40. Jones CL, Bhatla T, Blum R, Wang J, Paugh SW, Wen X, Bourgeois W, Bitterman DS, Raetz EA, Morrison DJ, Teachey DT, Evans WE, Garabedian MJ, Carroll WL. Loss of TBL1XR1 disrupts glucocorticoid receptor recruitment to chromatin and results in glucocorticoid resistance in a B-lymphoblastic leukemia model. J Biol Chem. 2014 Jul 25; 289(30):20502-15. PMID: 24895125.
    Citations: 30     Fields:    Translation:HumansCellsCTClinical Trials
  41. Heskel MA, Bitterman D, Atkin OK, Turnbull MH, Griffin KL. Seasonality of foliar respiration in two dominant plant species from the Arctic tundra: response to long-term warming and short-term temperature variability. Funct Plant Biol. 2014 Feb; 41(3):287-300. PMID: 32480989.
    Citations: 1     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.