Harvard Catalyst Profiles

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Amy Wen, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F32HL146070 (WEN, AMY) Feb 1, 2019 - Jan 31, 2021
    Lung-on-a-chip pulmonary fibrosis model for drug discovery
    Role: Principal Investigator
  2. F31HL129703 (WEN, AMY) Aug 19, 2015 - Aug 18, 2017
    Hemostasis-Independent targeted treatment of thrombosis
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kernan DL, Wen AM, Pitek AS, Steinmetz NF. Featured Article: Delivery of chemotherapeutic vcMMAE using tobacco mosaic virus nanoparticles. Exp Biol Med (Maywood). 2017 08; 242(14):1405-1411. PMID: 28675044.
    Citations:    Fields:    Translation:HumansCells
  2. Tiu BD, Kernan DL, Tiu SB, Wen AM, Zheng Y, Pokorski JK, Advincula RC, Steinmetz NF. Electrostatic layer-by-layer construction of fibrous TMV biofilms. Nanoscale. 2017 Jan 26; 9(4):1580-1590. PMID: 28070572.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Wallat JD, Czapar AE, Wang C, Wen AM, Wek KS, Yu X, Steinmetz NF, Pokorski JK. Optical and Magnetic Resonance Imaging Using Fluorous Colloidal Nanoparticles. Biomacromolecules. 2017 01 09; 18(1):103-112. PMID: 27992176.
    Citations:    Fields:    Translation:HumansCells
  4. Sreekanth KV, Alapan Y, ElKabbash M, Wen AM, Ilker E, Hinczewski M, Gurkan UA, Steinmetz NF, Strangi G. Enhancing the Angular Sensitivity of Plasmonic Sensors Using Hyperbolic Metamaterials. Adv Opt Mater. 2016 Nov; 4(11):1767-1772. PMID: 28649484.
    Citations: 2     
  5. Wen AM, Steinmetz NF. Design of virus-based nanomaterials for medicine, biotechnology, and energy. Chem Soc Rev. 2016 07 25; 45(15):4074-126. PMID: 27152673.
    Citations: 16     Fields:    Translation:HumansCells
  6. Tiu BD, Tiu SB, Wen AM, Lam P, Steinmetz NF, Advincula RC. Free-Standing, Nanopatterned Janus Membranes of Conducting Polymer-Virus Nanoparticle Arrays. Langmuir. 2016 06 21; 32(24):6185-93. PMID: 27244119.
    Citations: 1     Fields:    Translation:Cells
  7. Wen AM, Lee KL, Cao P, Pangilinan K, Carpenter BL, Lam P, Veliz FA, Ghiladi RA, Advincula RC, Steinmetz NF. Utilizing Viral Nanoparticle/Dendron Hybrid Conjugates in Photodynamic Therapy for Dual Delivery to Macrophages and Cancer Cells. Bioconjug Chem. 2016 05 18; 27(5):1227-35. PMID: 27077475.
    Citations: 5     Fields:    Translation:AnimalsCells
  8. Pitek AS, Wen AM, Shukla S, Steinmetz NF. Nanomedicine: The Protein Corona of Plant Virus Nanoparticles Influences their Dispersion Properties, Cellular Interactions, and In Vivo Fates (Small 13/2016). Small. 2016 Apr; 12(13):1682. PMID: 27038176.
  9. Ganguly R, Wen AM, Myer AB, Czech T, Sahu S, Steinmetz NF, Raman P. Anti-atherogenic effect of trivalent chromium-loaded CPMV nanoparticles in human aortic smooth muscle cells under hyperglycemic conditions in vitro. Nanoscale. 2016 Mar 28; 8(12):6542-54. PMID: 26935414.
    Citations: 1     Fields:    Translation:HumansCells
  10. Lee KL, Carpenter BL, Wen AM, Ghiladi RA, Steinmetz NF. High Aspect Ratio Nanotubes Formed by Tobacco Mosaic Virus for Delivery of Photodynamic Agents Targeting Melanoma. ACS Biomater Sci Eng. 2016 May 09; 2(5):838-844. PMID: 28713855.
    Citations: 4     
  11. Pitek AS, Wen AM, Shukla S, Steinmetz NF. The Protein Corona of Plant Virus Nanoparticles Influences their Dispersion Properties, Cellular Interactions, and In Vivo Fates. Small. 2016 Apr 06; 12(13):1758-69. PMID: 26853911.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  12. Lizotte PH, Wen AM, Sheen MR, Fields J, Rojanasopondist P, Steinmetz NF, Fiering S. In situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer. Nat Nanotechnol. 2016 Mar; 11(3):295-303. PMID: 26689376.
    Citations: 28     Fields:    Translation:AnimalsCellsPHPublic Health
  13. Wen AM, Le N, Zhou X, Steinmetz NF, Popkin DL. Tropism of CPMV to Professional Antigen Presenting Cells Enables a Platform to Eliminate Chronic Infections. ACS Biomater Sci Eng. 2015 Nov 09; 1(11):1050-1054. PMID: 27280157.
    Citations: 1     
  14. Au L, Meisch JP, Das LM, Binko AM, Boxer RS, Wen AM, Steinmetz NF, Lu KQ. Suppression of Hyperactive Immune Responses Protects against Nitrogen Mustard Injury. J Invest Dermatol. 2015 Dec; 135(12):2971-2981. PMID: 26288355.
    Citations: 6     Fields:    Translation:AnimalsCells
  15. Wen AM, Wang Y, Jiang K, Hsu GC, Gao H, Lee KL, Yang AC, Yu X, Simon DI, Steinmetz NF. Shaping bio-inspired nanotechnologies to target thrombosis for dual optical-magnetic resonance imaging. J Mater Chem B. 2015 Aug 07; 3(29):6037-6045. PMID: 26509036.
    Citations: 12     
  16. Shukla S, DiFranco NA, Wen AM, Commandeur U, Steinmetz NF. To Target or Not to Target: Active vs. Passive Tumor Homing of Filamentous Nanoparticles Based on Potato virus X. Cell Mol Bioeng. 2015; 8(3):433-444. PMID: 26316894.
    Citations: 4     
  17. Lee KL, Shukla S, Wu M, Ayat NR, El Sanadi CE, Wen AM, Edelbrock JF, Pokorski JK, Commandeur U, Dubyak GR, Steinmetz NF. Stealth filaments: Polymer chain length and conformation affect the in vivo fate of PEGylated potato virus X. Acta Biomater. 2015 Jun; 19:166-79. PMID: 25769228.
    Citations: 14     Fields:    Translation:Cells
  18. Wen AM, Podgornik R, Strangi G, Steinmetz NF. Photonics and plasmonics go viral: self-assembly of hierarchical metamaterials. Rend Lincei Sci Fis Nat. 2015 Aug; 26(2 Suppl):129-141. PMID: 28713533.
  19. Poudel L, Wen AM, French RH, Parsegian VA, Podgornik R, Steinmetz NF, Ching WY. Electronic structure and partial charge distribution of Doxorubicin in different molecular environments. Chemphyschem. 2015 May 18; 16(7):1451-60. PMID: 25728554.
    Citations: 1     Fields:    Translation:Cells
  20. Chariou PL, Lee KL, Wen AM, Gulati NM, Stewart PL, Steinmetz NF. Detection and imaging of aggressive cancer cells using an epidermal growth factor receptor (EGFR)-targeted filamentous plant virus-based nanoparticle. Bioconjug Chem. 2015 Feb 18; 26(2):262-269. PMID: 25611133.
    Citations: 6     Fields:    Translation:HumansCells
  21. Shukla S, Eber FJ, Nagarajan AS, DiFranco NA, Schmidt N, Wen AM, Eiben S, Twyman RM, Wege C, Steinmetz NF. The Impact of Aspect Ratio on the Biodistribution and Tumor Homing of Rigid Soft-Matter Nanorods. Adv Healthc Mater. 2015 Apr 22; 4(6):874-82. PMID: 25641794.
    Citations: 23     Fields:    Translation:HumansCells
  22. Wen AM, Infusino M, De Luca A, Kernan DL, Czapar AE, Strangi G, Steinmetz NF. Interface of physics and biology: engineering virus-based nanoparticles for biophotonics. Bioconjug Chem. 2015 Jan 21; 26(1):51-62. PMID: 25541212.
    Citations: 10     Fields:    Translation:HumansCells
  23. Adhikari P, Wen AM, French RH, Parsegian VA, Steinmetz NF, Podgornik R, Ching WY. Electronic structure, dielectric response, and surface charge distribution of RGD (1FUV) peptide. Sci Rep. 2014 Jul 08; 4:5605. PMID: 25001596.
    Citations: 4     Fields:    Translation:Cells
  24. Wen AM, Steinmetz NF. The aspect ratio of nanoparticle assemblies and the spatial arrangement of ligands can be optimized to enhance the targeting of cancer cells. Adv Healthc Mater. 2014 Nov; 3(11):1739-44. PMID: 24729309.
    Citations: 5     Fields:    Translation:AnimalsCells
  25. Rehor I, Slegerova J, Kucka J, Proks V, Petrakova V, Adam MP, Treussart F, Turner S, Bals S, Sacha P, Ledvina M, Wen AM, Steinmetz NF, Cigler P. Fluorescent nanodiamonds embedded in biocompatible translucent shells. Small. 2014 Mar 26; 10(6):1106-15. PMID: 24500945.
    Citations: 7     Fields:    Translation:HumansCells
  26. Shukla S, Wen AM, Ayat NR, Commandeur U, Gopalkrishnan R, Broome AM, Lozada KW, Keri RA, Steinmetz NF. Biodistribution and clearance of a filamentous plant virus in healthy and tumor-bearing mice. Nanomedicine (Lond). 2014 Feb; 9(2):221-35. PMID: 23834501.
    Citations: 14     Fields:    Translation:AnimalsCells
  27. Wen AM, Rambhia PH, French RH, Steinmetz NF. Design rules for nanomedical engineering: from physical virology to the applications of virus-based materials in medicine. J Biol Phys. 2013 Mar; 39(2):301-25. PMID: 23860875.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  28. Wen AM, Lee KL, Yildiz I, Bruckman MA, Shukla S, Steinmetz NF. Viral nanoparticles for in vivo tumor imaging. J Vis Exp. 2012 Nov 16; (69):e4352. PMID: 23183850.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  29. Wen AM, Shukla S, Saxena P, Aljabali AA, Yildiz I, Dey S, Mealy JE, Yang AC, Evans DJ, Lomonossoff GP, Steinmetz NF. Interior engineering of a viral nanoparticle and its tumor homing properties. Biomacromolecules. 2012 Dec 10; 13(12):3990-4001. PMID: 23121655.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  30. Wen AM, Ryan MJ, Yang AC, Breitenkamp K, Pokorski JK, Steinmetz NF. Photodynamic activity of viral nanoparticles conjugated with C60. Chem Commun (Camb). 2012 Sep 18; 48(72):9044-6. PMID: 22858632.
    Citations: 2     Fields:    Translation:HumansCells
  31. Shukla S, Ablack AL, Wen AM, Lee KL, Lewis JD, Steinmetz NF. Increased tumor homing and tissue penetration of the filamentous plant viral nanoparticle Potato virus X. Mol Pharm. 2013 Jan 07; 10(1):33-42. PMID: 22731633.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  32. Yildiz I, Tsvetkova I, Wen AM, Shukla S, Masarapu MH, Dragnea B, Steinmetz NF. Engineering of Brome mosaic virus for biomedical applications. RSC Adv. 2012 May 07; 2(9):3670-3677. PMID: 28018580.
    Citations: 3     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.