Harvard Catalyst Profiles

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Vignesh Shanmugam, M.D.

Title
Institution
Department
Address
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Biography
education and training
Weill Cornell Medical College in Qatar, Doha, QatarM.D.04/2016Medicine
Brigham and Women's Hospital, Boston, MA, USAResidency06/2019Pathology and Laboratory Medicine
Brigham and Women's Hospital, Boston, MA, USAFellowship06/2020Hematopathology

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Liu S, Iorgulescu JB, Li S, Borji M, Barrera-Lopez IA, Shanmugam V, Lyu H, Morriss JW, Garcia ZN, Murray E, Reardon DA, Yoon CH, Braun DA, Livak KJ, Wu CJ, Chen F. Spatial maps of T cell receptors and transcriptomes reveal distinct immune niches and interactions in the adaptive immune response. Immunity. 2022 10 11; 55(10):1940-1952.e5. PMID: 36223726; PMCID: PMC9745674.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  2. Cable DM, Murray E, Shanmugam V, Zhang S, Zou LS, Diao M, Chen H, Macosko EZ, Irizarry RA, Chen F. Cell type-specific inference of differential expression in spatial transcriptomics. Nat Methods. 2022 09; 19(9):1076-1087. PMID: 36050488.
    Citations: 3     Fields:    Translation:Cells
  3. Larocca C, Shanmugam V, Zemmour D, Antin JH, Lane AA. Shared Clonal Origin of Multiple Histiocytic and Dendritic Neoplasms and Polycythemia Vera, Follicular Lymphoma in 1 Patient. Am J Dermatopathol. 2022 12 01; 44(12):929-932. PMID: 35642960.
    Citations:    Fields:    
  4. Lee K, Evans MG, Yang L, Ng S, Snowden C, Khodadoust M, Brown RA, Trum NA, Querfeld C, Doan LT, Song J, Zhang H, Gru AA, Wood GS, Wada DA, Shanmugam V, Haun PL, Aster JC, Duncan LM, Guitart J, Weinstock DM, Nardi V, Choi J. Primary cytotoxic T-cell lymphomas harbor recurrent targetable alterations in the JAK-STAT pathway. Blood. 2021 12 09; 138(23):2435-2440. PMID: 34432866; PMCID: PMC8662071.
    Citations:    Fields:    Translation:HumansCells
  5. Sewastianik T, Straubhaar JR, Zhao JJ, Samur MK, Adler K, Tanton HE, Shanmugam V, Nadeem O, Dennis PS, Pillai V, Wang J, Jiang M, Lin J, Huang Y, Brooks D, Bouxsein M, Dorfman DM, Pinkus GS, Robbiani DF, Ghobrial IM, Budnik B, Jarolim P, Munshi NC, Anderson KC, Carrasco RD. miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms. Blood. 2021 04 08; 137(14):1905-1919. PMID: 33751108; PMCID: PMC8033455.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Leung SOA, Feldman S, Kalyanaraman R, Shanmugam V, Worley MJ, Berkowitz RS, Horowitz NS, Feltmate CM, Muto MG, Lee LJ, King MT, Einarsson JI, Ajao MO, Elias KM. Triaging abnormal cervical cancer screening tests using p16INK4a detection by ELISA on fresh cervical samples. Am J Reprod Immunol. 2021 07; 86(1):e13394. PMID: 33501727.
    Citations:    Fields:    Translation:HumansCells
  7. Raman HS, Shanmugam V, Li J, Steensma DP, Kim AS, Luskin MR. NPM1-mutant acute myeloid leukemia relapsing as acute lymphoblastic leukemia with clonal persistence of IDH1 mutation. Leuk Lymphoma. 2021 07; 62(7):1790-1792. PMID: 33586600.
    Citations:    Fields:    Translation:Humans
  8. Behzadi F, Suh CH, Jo VY, Shanmugam V, Morgan EA, Guenette JP. Imaging of IgG4-Related Disease in the Head and Neck: A Systematic Review, Case Series, and Pathophysiology Update. J Neuroradiol. 2021 Sep; 48(5):369-378. PMID: 33516733.
    Citations: 2     Fields:    Translation:Humans
  9. Shanmugam V, Craig JW, Hilton LK, Nguyen MH, Rushton CK, Fahimdanesh K, Lovitch S, Ferland B, Scott DW, Aster JC. Notch activation is pervasive in SMZL and uncommon in DLBCL: implications for Notch signaling in B-cell tumors. Blood Adv. 2021 01 12; 5(1):71-83. PMID: 33570635.
    Citations: 4     Fields:    Translation:HumansCells
  10. Haghayeghi K, Robinson-Bostom L, Olszewski A, Jackson CL, Patel NR, Sewastianik T, Carrasco RD, Shanmugam V, Treaba DO. Aggressive CD4/CD8 Double-Negative Primary Cutaneous T-Cell Lymphoma With Dural Invasion: A Rare Presentation of Mycosis Fungoides? Am J Dermatopathol. 2021 Jan 01; 43(1):63-66. PMID: 32675473.
    Citations:    Fields:    Translation:Humans
  11. Rana A, Lowe A, Lithgow M, Horback K, Janovitz T, Da Silva A, Tsai H, Shanmugam V, Bayat A, Shah P. Use of Deep Learning to Develop and Analyze Computational Hematoxylin and Eosin Staining of Prostate Core Biopsy Images for Tumor Diagnosis. JAMA Netw Open. 2020 05 01; 3(5):e205111. PMID: 32432709.
    Citations: 11     Fields:    Translation:Humans
  12. Shanmugam V, Parnes A, Kalyanaraman R, Morgan EA, Kim AS. Clinical utility of targeted next-generation sequencing-based screening of peripheral blood in the evaluation of cytopenias. Blood. 2019 12 12; 134(24):2222-2225. PMID: 31697812.
    Citations: 3     Fields:    Translation:HumansCells
  13. Sewastianik T, Guerrera ML, Adler K, Dennis PS, Wright K, Shanmugam V, Huang Y, Tanton H, Jiang M, Kofides A, Demos MG, Dalgarno A, Patel NA, Nag A, Pinkus GS, Yang G, Hunter ZR, Jarolim P, Munshi NC, Treon SP, Carrasco RD. Human MYD88L265P is insufficient by itself to drive neoplastic transformation in mature mouse B cells. Blood Adv. 2019 11 12; 3(21):3360-3374. PMID: 31698464.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  14. Shanmugam V, Griffin GK, Jacobsen ED, Fletcher CDM, Sholl LM, Hornick JL. Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma. Mod Pathol. 2019 06; 32(6):830-843. PMID: 30626916.
    Citations: 19     Fields:    Translation:HumansCells
  15. Shanmugam V, Mitchell RN, Padera RF, Wiesel O. Enterovascular Fistula: An Under-Recognized Complication Related to Therapy for Esophageal Carcinoma. J Laparoendosc Adv Surg Tech A. 2019 May; 29(5):583-588. PMID: 30562139.
    Citations:    Fields:    Translation:Humans
  16. Shanmugam V, Dorfman DM. Acute myeloid leukemia with minimal differentiation (AML M0) mimicking acute lymphoblastic leukemia. Am J Hematol. 2019 08; 94(8):955-956. PMID: 30431665.
    Citations:    Fields:    Translation:HumansCells
  17. Shanmugam V, Morgan EA, DeAngelo DJ, Kim AS. Many faces of the same myeloid neoplasm: a case of leukaemia cutis with mixed histiocytic and Langerhans cell differentiation. J Clin Pathol. 2019 01; 72(1):93-96. PMID: 30093508.
    Citations: 1     Fields:    Translation:HumansCells
  18. Jacobsen E, Shanmugam V, Jagannathan J. Rosai-Dorfman Disease with Activating KRAS Mutation - Response to Cobimetinib. N Engl J Med. 2017 12 14; 377(24):2398-2399. PMID: 29236635.
    Citations: 25     Fields:    Translation:Humans
  19. Shanmugam V, Craig JW, Hornick JL, Morgan EA, Pinkus GS, Pozdnyakova O. Cyclin D1 Is Expressed in Neoplastic Cells of Langerhans Cell Histiocytosis but Not Reactive Langerhans Cell Proliferations. Am J Surg Pathol. 2017 Oct; 41(10):1390-1396. PMID: 28622183.
    Citations: 11     Fields:    Translation:HumansCells
  20. Shanmugam V, Dorfman DM. An unusual case of chronic lymphocytic leukemia/small lymphocytic lymphoma with nodular morphology. Leuk Lymphoma. 2017 08; 58(8):2014-2016. PMID: 27919167.
    Citations:    Fields:    Translation:Humans
  21. Shanmugam V, Geraghty B, DeSimone RA, Hoda RS. Diagnostic value of positive urinary cytology in the detection of recurrent urothelial carcinoma: 10-Year Experience at the Papanicolaou Cytology Laboratory. Diagn Cytopathol. 2016 Dec; 44(12):975-979. PMID: 27665730.
    Citations:    Fields:    Translation:Humans
  22. Strulovici-Barel Y, Shaykhiev R, Salit J, Deeb RS, Krause A, Kaner RJ, Vincent TL, Agosto-Perez F, Wang G, Hollmann C, Shanmugam V, Almulla AM, Sattar H, Mahmoud M, Mezey JG, Gross SS, Staudt MR, Walters MS, Crystal RG. Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers. Am J Respir Crit Care Med. 2016 09 01; 194(5):587-95. PMID: 27007171; PMCID: PMC5027211.
    Citations: 13     Fields:    Translation:HumansCells
  23. Shanmugam V, Margolskee E, Kluk M, Giorgadze T, Orazi A. Rosai-Dorfman Disease Harboring an Activating KRAS K117N Missense Mutation. Head Neck Pathol. 2016 Sep; 10(3):394-9. PMID: 26922062.
    Citations: 17     Fields:    Translation:Humans
  24. Ibrahim FA, Shanmugam V, Amer A, El-Omri H, Al-Sabbagh A, Taha RY, Soliman DS. An Unusual Case of Hepatosplenic aß T-Cell Lymphoma Presenting with Coombs'-Negative Hemolytic Anemia. Clin Med Insights Oncol. 2015; 9:123-8. PMID: 26688667; PMCID: PMC4668954.
    Citations: 2     
  25. Haddad N, Ikard C, Hiatt K, Shanmugam V, Schmidley J. Recurrent status epilepticus as the primary neurological manifestation of CADASIL: A case report. Epilepsy Behav Case Rep. 2015; 3:26-9. PMID: 25870789; PMCID: PMC4389202.
    Citations: 2     
  26. Vignesh Shanmugam , Amro Wafi , Nawaf Al-Taweel , Dietrich Büsselberg. Journal of Local and Global Health Sciences. Disruption of circadian rhythm increases the risk of cancer, metabolic syndrome and cardiovascular disease. 2013; 3. View Publication.
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