Harvard Catalyst Profiles

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Karen Dixon, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hernández-Malmierca P, Vonficht D, Schnell A, Uckelmann HJ, Bollhagen A, Mahmoud MAA, Landua SL, van der Salm E, Trautmann CL, Raffel S, Grünschläger F, Lutz R, Ghosh M, Renders S, Correia N, Donato E, Dixon KO, Hirche C, Andresen C, Robens C, Werner PS, Boch T, Eisel D, Osen W, Pilz F, Przybylla A, Klein C, Buchholz F, Milsom MD, Essers MAG, Eichmüller SB, Hofmann WK, Nowak D, Hübschmann D, Hundemer M, Thiede C, Bullinger L, Müller-Tidow C, Armstrong SA, Trumpp A, Kuchroo VK, Haas S. Antigen presentation safeguards the integrity of the hematopoietic stem cell pool. Cell Stem Cell. 2022 05 05; 29(5):760-775.e10. PMID: 35523139; PMCID: PMC9202612.
    Citations:    Fields:    Translation:Cells
  2. Tang R, Acharya N, Subramanian A, Purohit V, Tabaka M, Hou Y, He D, Dixon KO, Lambden C, Xia J, Rozenblatt-Rosen O, Sobel RA, Wang C, Regev A, Anderson AC, Kuchroo VK. Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function. Sci Immunol. 2022 03 11; 7(69):eabm0631. PMID: 35275752; PMCID: PMC9273260.
    Citations:    Fields:    Translation:AnimalsCells
  3. Dixon KO, Tabaka M, Schramm MA, Xiao S, Tang R, Dionne D, Anderson AC, Rozenblatt-Rosen O, Regev A, Kuchroo VK. TIM-3 restrains anti-tumour immunity by regulating inflammasome activation. Nature. 2021 07; 595(7865):101-106. PMID: 34108686; PMCID: PMC8627694.
    Citations: 29     Fields:    Translation:AnimalsCells
  4. Zhu C, Dixon KO, Newcomer K, Gu G, Xiao S, Zaghouani S, Schramm MA, Wang C, Zhang H, Goto K, Christian E, Rangachari M, Rosenblatt-Rosen O, Okada H, Mak T, Singer M, Regev A, Kuchroo V. Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion. Sci Adv. 2021 04; 7(18). PMID: 33931442; PMCID: PMC8087420.
    Citations: 2     Fields:    
  5. Dixon KO, Kuchroo VK. IL-18: throwing off the shackles to boost anti-tumor immunity. Cell Res. 2020 10; 30(10):831-832. PMID: 32811976.
    Citations: 1     Fields:    
  6. Acharya N, Madi A, Zhang H, Klapholz M, Escobar G, Dulberg S, Christian E, Ferreira M, Dixon KO, Fell G, Tooley K, Mangani D, Xia J, Singer M, Bosenberg M, Neuberg D, Rozenblatt-Rosen O, Regev A, Kuchroo VK, Anderson AC. Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment. Immunity. 2020 09 15; 53(3):658-671.e6. PMID: 32937153; PMCID: PMC7682805.
    Citations: 34     Fields:    Translation:AnimalsCells
  7. Dixon KO, Das M, Kuchroo VK. Human disease mutations highlight the inhibitory function of TIM-3. Nat Genet. 2018 12; 50(12):1640-1641. PMID: 30405215; PMCID: PMC6452640.
    Citations: 6     Fields:    Translation:HumansCells
  8. Dixon KO, Schorer M, Nevin J, Etminan Y, Amoozgar Z, Kondo T, Kurtulus S, Kassam N, Sobel RA, Fukumura D, Jain RK, Anderson AC, Kuchroo VK, Joller N. Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity. J Immunol. 2018 04 15; 200(8):3000-3007. PMID: 29500245; PMCID: PMC5893394.
    Citations: 51     Fields:    Translation:Animals
  9. Dixon KO, O'Flynn J, Klar-Mohamad N, Daha MR, van Kooten C. Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-?. Eur J Immunol. 2017 03; 47(3):470-480. PMID: 28105653; PMCID: PMC5363362.
    Citations: 12     Fields:    Translation:HumansCells
  10. O'Flynn J, van der Pol P, Dixon KO, Prohászka Z, Daha MR, van Kooten C. Monomeric C-reactive protein inhibits renal cell-directed complement activation mediated by properdin. Am J Physiol Renal Physiol. 2016 06 01; 310(11):F1308-16. PMID: 26984957.
    Citations: 9     Fields:    Translation:HumansCells
  11. Dixon KO, van der Kooij SW, Vignali DA, van Kooten C. Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members. Eur J Immunol. 2015 Jun; 45(6):1736-47. PMID: 25820702.
    Citations: 44     Fields:    Translation:HumansCells
  12. Dixon KO, Rossmann L, Kamerling SW, van Kooten C. Human renal fibroblasts generate dendritic cells with a unique regulatory profile. Immunol Cell Biol. 2014 Sep; 92(8):688-98. PMID: 24913322.
    Citations: 5     Fields:    Translation:HumansCells
  13. Dixon KO, O'Flynn J, van der Kooij SW, van Kooten C. Phagocytosis of apoptotic or necrotic cells differentially regulates the transcriptional expression of IL-12 family members in dendritic cells. J Leukoc Biol. 2014 Aug; 96(2):313-24. PMID: 24782489.
    Citations: 10     Fields:    Translation:HumansCells
  14. O'Flynn J, Dixon KO, Faber Krol MC, Daha MR, van Kooten C. Myeloperoxidase directs properdin-mediated complement activation. J Innate Immun. 2014; 6(4):417-25. PMID: 24355864.
    Citations: 22     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.