Harvard Catalyst Profiles

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Mehdi Jorfi, Ph.D.



Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ning S, Jorfi M, Patel SR, Kim DY, Tanzi RE. Neurotechnological Approaches to the Diagnosis and Treatment of Alzheimer's Disease. Front Neurosci. 2022; 16:854992. PMID: 35401082; PMCID: PMC8989850.
  2. Lotlikar MS, Tarantino MB, Jorfi M, Kovacs DM, Tanzi RE, Bhattacharyya R. Microfluidic separation of axonal and somal compartments of neural progenitor cells differentiated in a 3D matrix. STAR Protoc. 2022 03 18; 3(1):101028. PMID: 35059649; PMCID: PMC8755568.
    Citations:    Fields:    Translation:HumansCells
  3. Kim JJ, Jorfi M, Tanzi RE, Kim DY, Doyle PS, Irimia D. Patterning of interconnected human brain spheroids. Lab Chip. 2021 09 14; 21(18):3532-3540. PMID: 34286713; PMCID: PMC9142085.
    Citations:    Fields:    Translation:HumansCells
  4. McAlpine CS, Park J, Griciuc A, Kim E, Choi SH, Iwamoto Y, Kiss MG, Christie KA, Vinegoni C, Poller WC, Mindur JE, Chan CT, He S, Janssen H, Wong LP, Downey J, Singh S, Anzai A, Kahles F, Jorfi M, Feruglio PF, Sadreyev RI, Weissleder R, Kleinstiver BP, Nahrendorf M, Tanzi RE, Swirski FK. Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease. Nature. 2021 07; 595(7869):701-706. PMID: 34262178; PMCID: PMC8934148.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  5. Bhattacharyya R, Black SE, Lotlikar MS, Fenn RH, Jorfi M, Kovacs DM, Tanzi RE. Axonal generation of amyloid-ß from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes. Cell Rep. 2021 05 18; 35(7):109134. PMID: 34010653; PMCID: PMC8287518.
    Citations: 5     Fields:    Translation:HumansCells
  6. von Maydell D, Jorfi M. A Synergistic Engineering Approach to Build Human Brain Spheroids. Methods Mol Biol. 2021; 2258:151-169. PMID: 33340360.
    Citations:    Fields:    Translation:HumansCells
  7. von Maydell D, Jorfi M. The interplay between microglial states and major risk factors in Alzheimer's disease through the eyes of single-cell RNA-sequencing: beyond black and white. J Neurophysiol. 2019 10 01; 122(4):1291-1296. PMID: 31365320.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  8. Ning S, Jorfi M. Beyond the sleep-amyloid interactions in Alzheimer's disease pathogenesis. J Neurophysiol. 2019 07 01; 122(1):1-4. PMID: 30864847.
    Citations: 2     Fields:    Translation:HumansAnimals
  9. Roushan M, Jorfi M, Mishra A, Wong KHK, Jorgensen J, Ell E, Markmann JF, Lee J, Irimia D. Trapped Chromatin Fibers Damage Flowing Red Blood Cells. Adv Biosyst. 2018 Oct; 2(10). PMID: 31223642.
    Citations: 1     Fields:    
  10. DeVos SL, Corjuc BT, Commins C, Dujardin S, Bannon RN, Corjuc D, Moore BD, Bennett RE, Jorfi M, Gonzales JA, Dooley PM, Roe AD, Pitstick R, Irimia D, Frosch MP, Carlson GA, Hyman BT. Tau reduction in the presence of amyloid-ß prevents tau pathology and neuronal death in vivo. Brain. 2018 07 01; 141(7):2194-2212. PMID: 29733334; PMCID: PMC6022692.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  11. Jorfi M, D'Avanzo C, Tanzi RE, Kim DY, Irimia D. Human Neurospheroid Arrays for In Vitro Studies of Alzheimer's Disease. Sci Rep. 2018 02 05; 8(1):2450. PMID: 29402979.
    Citations: 34     Fields:    Translation:HumansCells
  12. Jorfi M, D'Avanzo C, Kim DY, Irimia D. Three-Dimensional Models of the Human Brain Development and Diseases. Adv Healthc Mater. 2018 01; 7(1). PMID: 28845922; PMCID: PMC5762251.
    Citations: 24     Fields:    Translation:Humans
  13. Nguyen JK, Jorfi M, Buchanan KL, Park DJ, Foster EJ, Tyler DJ, Rowan SJ, Weder C, Capadona JR. Influence of resveratrol release on the tissue response to mechanically adaptive cortical implants. Acta Biomater. 2016 Jan; 29:81-93. PMID: 26553391.
    Citations: 26     Fields:    Translation:AnimalsCells
  14. Jorfi M, Skousen JL, Weder C, Capadona JR. Progress towards biocompatible intracortical microelectrodes for neural interfacing applications. J Neural Eng. 2015 Feb; 12(1):011001. PMID: 25460808; PMCID: PMC4428498.
    Citations: 109     Fields:    Translation:Cells
  15. Jorfi M, Voirin G, Foster EJ, Weder C. Physiologically responsive, mechanically adaptive polymer optical fibers for optogenetics. Opt Lett. 2014 May 15; 39(10):2872-5. PMID: 24978225.
    Citations: 4     Fields:    
  16. Potter KA, Jorfi M, Householder KT, Foster EJ, Weder C, Capadona JR. Curcumin-releasing mechanically adaptive intracortical implants improve the proximal neuronal density and blood-brain barrier stability. Acta Biomater. 2014 May; 10(5):2209-22. PMID: 24468582.
    Citations: 42     Fields:    Translation:AnimalsCells
  17. Jorfi M, Roberts MN, Foster EJ, Weder C. Physiologically responsive, mechanically adaptive bio-nanocomposites for biomedical applications. ACS Appl Mater Interfaces. 2013 Feb; 5(4):1517-26. PMID: 23379302.
    Citations: 11     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.