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profileKeisuke Kosumi, Ph.D., M.D.

TitleResearch Fellow in Pathology (EXT)
InstitutionBrigham and Women's Hospital
DepartmentPathology
AddressBrigham and Women's Hospital
Dept of Medicine
75 Francis St
Boston MA 02115
Phone617/632-9146
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Liu L, Nishihara R, Qian ZR, Tabung FK, Nevo D, Zhang X, Song M, Cao Y, Mima K, Masugi Y, Shi Y, da Silva A, Twombly T, Gu M, Li W, Hamada T, Kosumi K, Inamura K, Nowak JA, Drew DA, Lochhead P, Nosho K, Wu K, Wang M, Garrett WS, Chan AT, Fuchs CS, Giovannucci EL, Ogino S. Association Between Inflammatory Diet Pattern and Risk of Colorectal Carcinoma Subtypes Classified by Immune Responses to Tumor. Gastroenterology. 2017 Aug 30. PMID: 28865736.
    View in: PubMed
  2. Mehta RS, Nishihara R, Cao Y, Song M, Mima K, Qian ZR, Nowak JA, Kosumi K, Hamada T, Masugi Y, Bullman S, Drew DA, Kostic AD, Fung TT, Garrett WS, Huttenhower C, Wu K, Meyerhardt JA, Zhang X, Willett WC, Giovannucci EL, Fuchs CS, Chan AT, Ogino S. Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue. JAMA Oncol. 2017 Jul 01; 3(7):921-927. PMID: 28125762.
    View in: PubMed
  3. Hanyuda A, Cao Y, Hamada T, Nowak JA, Qian ZR, Masugi Y, da Silva A, Liu L, Kosumi K, Soong TR, Jhun I, Wu K, Zhang X, Song M, Meyerhardt JA, Chan AT, Fuchs CS, Giovannucci EL, Ogino S, Nishihara R. Body mass index and risk of colorectal carcinoma subtypes classified by tumor differentiation status. Eur J Epidemiol. 2017 May; 32(5):393-407. PMID: 28510098.
    View in: PubMed
  4. Hamada T, Cao Y, Qian ZR, Masugi Y, Nowak JA, Yang J, Song M, Mima K, Kosumi K, Liu L, Shi Y, da Silva A, Gu M, Li W, Keum N, Zhang X, Wu K, Meyerhardt JA, Giovannucci EL, Giannakis M, Rodig SJ, Freeman GJ, Nevo D, Wang M, Chan AT, Fuchs CS, Nishihara R, Ogino S. Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status. J Clin Oncol. 2017 Jun 01; 35(16):1836-1844. PMID: 28406723.
    View in: PubMed
  5. Keum N, Yuan C, Nishihara R, Zoltick E, Hamada T, Martinez Fernandez A, Zhang X, Hanyuda A, Liu L, Kosumi K, Nowak JA, Jhun I, Soong TR, Morikawa T, Tabung FK, Qian ZR, Fuchs CS, Meyerhardt JA, Chan AT, Ng K, Ogino S, Giovannucci EL, Wu K. Dietary glycemic and insulin scores and colorectal cancer survival by tumor molecular biomarkers. Int J Cancer. 2017 Jun 15; 140(12):2648-2656. PMID: 28268248.
    View in: PubMed
  6. Tokunaga R, Sakamoto Y, Nakagawa S, Izumi D, Kosumi K, Taki K, Higashi T, Miyata T, Miyamoto Y, Yoshida N, Baba H. Comparison of systemic inflammatory and nutritional scores in colorectal cancer patients who underwent potentially curative resection. Int J Clin Oncol. 2017 Aug; 22(4):740-748. PMID: 28213742.
    View in: PubMed
  7. Kosumi K, Masugi Y, Yang J, Qian ZR, Kim SA, Li W, Shi Y, da Silva A, Hamada T, Liu L, Gu M, Twombly TS, Cao Y, Barbie DA, Nosho K, Baba H, Garrett WS, Meyerhardt JA, Giovannucci EL, Chan AT, Fuchs CS, Ogino S, Nishihara R. Tumor SQSTM1 (p62) expression and T cells in colorectal cancer. Oncoimmunology. 2017; 6(3):e1284720. PMID: 28405513.
    View in: PubMed
  8. Yoshida N, Harada K, Baba Y, Kosumi K, Iwatsuki M, Kinoshita K, Nakamura K, Sakamoto Y, Miyamoto Y, Karashima R, Mima K, Sawayama H, Ohuchi M, Chikamoto A, Imamura Y, Watanabe M, Baba H. Preoperative controlling nutritional status (CONUT) is useful to estimate the prognosis after esophagectomy for esophageal cancer. Langenbecks Arch Surg. 2017 Mar; 402(2):333-341. PMID: 28138759.
    View in: PubMed
  9. Nakamura K, Yoshida N, Baba Y, Kosumi K, Uchihara T, Kiyozumi Y, Ohuchi M, Ishimoto T, Iwatsuki M, Sakamoto Y, Watanabe M, Baba H. Elevated preoperative neutrophil-to-lymphocytes ratio predicts poor prognosis after esophagectomy in T1 esophageal cancer. Int J Clin Oncol. 2017 Jun; 22(3):469-475. PMID: 28097441.
    View in: PubMed
  10. Mima K, Cao Y, Chan AT, Qian ZR, Nowak JA, Masugi Y, Shi Y, Song M, da Silva A, Gu M, Li W, Hamada T, Kosumi K, Hanyuda A, Liu L, Kostic AD, Giannakis M, Bullman S, Brennan CA, Milner DA, Baba H, Garraway LA, Meyerhardt JA, Garrett WS, Huttenhower C, Meyerson M, Giovannucci EL, Fuchs CS, Nishihara R, Ogino S. Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location. Clin Transl Gastroenterol. 2016 Nov 03; 7(11):e200. PMID: 27811909.
    View in: PubMed
  11. Tokunaga R, Sakamoto Y, Nakagawa S, Ohuchi M, Izumi D, Kosumi K, Taki K, Higashi T, Miyamoto Y, Yoshida N, Oki E, Watanabe M, Baba H. CONUT: a novel independent predictive score for colorectal cancer patients undergoing potentially curative resection. Int J Colorectal Dis. 2017 Jan; 32(1):99-106. PMID: 27726014.
    View in: PubMed
  12. Nakamura K, Baba Y, Kosumi K, Harada K, Shigaki H, Miyake K, Kiyozumi Y, Ohuchi M, Kurashige J, Ishimoto T, Iwatsuki M, Sakamoto Y, Yoshida N, Watanabe M, Nakao M, Baba H. UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma. Oncotarget. 2016 Sep 06; 7(36):57821-57831. PMID: 27507047.
    View in: PubMed
  13. Akiyama T, Miyamoto Y, Sakamoto Y, Tokunaga R, Kosumi K, Shigaki H, Kurashige J, Iwatsuki M, Baba Y, Yoshida N, Baba H. Cancer-related multiple brain infarctions caused by Trousseau syndrome in a patient with metastatic colon cancer: a case report. Surg Case Rep. 2016 Dec; 2(1):91. PMID: 27595586; PMCID: PMC5011467.
  14. Kitano Y, Iwatsuki M, Kurashige J, Kuroda D, Kosumi K, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Haga Y, Baba H. Estimation of Physiologic Ability and Surgical Stress (E-PASS) versus modified E-PASS for prediction of postoperative complications in elderly patients who undergo gastrectomy for gastric cancer. Int J Clin Oncol. 2017 Feb; 22(1):80-87. PMID: 27518251.
    View in: PubMed
  15. Kosumi K, Baba Y, Ozaki N, Akiyama T, Harada K, Shigaki H, Imamura Y, Iwatsuki M, Yoshida N, Watanabe M, Baba H. Transnasal inner drainage: an option for managing anastomotic leakage after esophagectomy. Langenbecks Arch Surg. 2016 Sep; 401(6):903-8. PMID: 27516076.
    View in: PubMed
  16. Yoshida N, Baba Y, Shigaki H, Harada K, Iwatsuki M, Kurashige J, Sakamoto Y, Miyamoto Y, Ishimoto T, Kosumi K, Tokunaga R, Imamura Y, Ida S, Hiyoshi Y, Watanabe M, Baba H. Preoperative Nutritional Assessment by Controlling Nutritional Status (CONUT) is Useful to estimate Postoperative Morbidity After Esophagectomy for Esophageal Cancer. World J Surg. 2016 Aug; 40(8):1910-7. PMID: 27220507.
    View in: PubMed
  17. Harada K, Baba Y, Shigaki H, Ishimoto T, Miyake K, Kosumi K, Tokunaga R, Izumi D, Ohuchi M, Nakamura K, Kiyozumi Y, Kurashige J, Iwatsuki M, Miyamoto Y, Sakamoto Y, Yoshida N, Watanabe M, Baba H. Prognostic and clinical impact of PIK3CA mutation in gastric cancer: pyrosequencing technology and literature review. BMC Cancer. 2016 Jul 07; 16:400. PMID: 27388016; PMCID: PMC4936296.
  18. Uemura N, Kurashige J, Kosumi K, Iwatsuki M, Yamashita K, Iwagami S, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Honda Y, Mikami Y, Baba H. Early gastric cancer metastasizing to the rectum, possibly via a hematogenous route: a case report and review of literature. Surg Case Rep. 2016 Dec; 2(1):58. PMID: 27271470; PMCID: PMC4896888.
  19. Yoshida N, Baba Y, Shigaki H, Harada K, Iwatsuki M, Sakamoto Y, Miyamoto Y, Kurashige J, Kosumi K, Tokunaga R, Watanabe M, Baba H. Risk factors of early recurrence within 6 months after esophagectomy following neoadjuvant chemotherapy for resectable advanced esophageal squamous cell carcinoma. Int J Clin Oncol. 2016 Dec; 21(6):1071-1078. PMID: 27255393.
    View in: PubMed
  20. Zhou L, Baba Y, Kitano Y, Miyake K, Zhang X, Yamamura K, Kosumi K, Kaida T, Arima K, Taki K, Higashi T, Imai K, Hashimoto D, Yamashita Y, Chikamoto A, Beppu T, Tan X, Baba H. KRAS, BRAF, and PIK3CA mutations, and patient prognosis in 126 pancreatic cancers: pyrosequencing technology and literature review. Med Oncol. 2016 Apr; 33(4):32. PMID: 26927447.
    View in: PubMed
  21. Sakamoto Y, Tokunaga R, Miyamoto Y, Ohuchi M, Nakamura K, Kosumi K, Harada K, Shigaki H, Kurashige J, Iwatsuki M, Baba Y, Yoshida N, Baba H. Retroileal colorectal anastomosis after extended left colectomy: application for laparoscopic surgery. Surg Today. 2016 Dec; 46(12):1476-1478. PMID: 26892331.
    View in: PubMed
  22. Kosumi K, Baba Y, Ishimoto T, Harada K, Nakamura K, Ohuchi M, Kiyozumi Y, Izumi D, Tokunaga R, Taki K, Higashi T, Miyata T, Shigaki H, Kurashige J, Hiyoshi Y, Iwatsuki M, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Oki E, Watanabe M, Baba H. APOBEC3B is an enzymatic source of molecular alterations in esophageal squamous cell carcinoma. Med Oncol. 2016 Mar; 33(3):26. PMID: 26880326.
    View in: PubMed
  23. Harada K, Baba Y, Ishimoto T, Shigaki H, Kosumi K, Yoshida N, Watanabe M, Baba H. The role of microRNA in esophageal squamous cell carcinoma. J Gastroenterol. 2016 Jun; 51(6):520-30. PMID: 26794004.
    View in: PubMed
  24. Yoshida N, Baba Y, Hiyoshi Y, Shigaki H, Kurashige J, Sakamoto Y, Miyamoto Y, Iwatsuki M, Ishimoto T, Kosumi K, Sugihara H, Harada K, Tokunaga R, Izumi D, Watanabe M, Baba H. Duration of Smoking Cessation and Postoperative Morbidity After Esophagectomy for Esophageal Cancer: How Long Should Patients Stop Smoking Before Surgery? World J Surg. 2016 Jan; 40(1):142-7. PMID: 26330238.
    View in: PubMed
  25. Yoshida N, Baba Y, Shigaki H, Shiraishi S, Harada K, Watanabe M, Iwatsuki M, Kurashige J, Sakamoto Y, Miyamoto Y, Ishimoto T, Kosumi K, Tokunaga R, Yamashita Y, Baba H. Effect of Esophagus Position on Surgical Difficulty and Postoperative Morbidities After Thoracoscopic Esophagectomy. Semin Thorac Cardiovasc Surg. 2016; 28(1):172-9. PMID: 27568157.
    View in: PubMed
  26. Izumi D, Yoshida N, Watanabe M, Shiraishi S, Ishimoto T, Kosumi K, Tokunaga R, Taki K, Higashi T, Harada K, Miyata T, Ida S, Imamura Y, Iwagami S, Baba Y, Sakamoto Y, Miyamoto Y, Yamashita Y, Baba H. Tumor/normal esophagus ratio in (18)F-fluorodeoxyglucose positron emission tomography/computed tomography for response and prognosis stratification after neoadjuvant chemotherapy for esophageal squamous cell carcinoma. J Gastroenterol. 2016 Aug; 51(8):788-95. PMID: 26671045.
    View in: PubMed
  27. Kosumi K, Baba Y, Harada K, Yoshida N, Watanabe M, Baba H. Perioperative Blood Transfusion, Age at Surgery, and Prognosis in a Database of 526 Upper Gastrointestinal Cancers. Dig Surg. 2015; 32(6):445-53. PMID: 26550999.
    View in: PubMed
  28. Koga Y, Baba Y, Harada K, Kosumi K, Shigaki H, Kurashige J, Ishimoto T, Iwatsuki M, Miyamoto Y, Sakamoto Y, Yoshida N, Baba H. Multiple skeletal muscle metastases from poorly differentiated gastric adenocarcinoma. Surg Case Rep. 2015 Dec; 1(1):105. PMID: 26943429; PMCID: PMC4607684.
  29. Tokunaga R, Sakamoto Y, Nakagawa S, Miyake K, Izumi D, Kosumi K, Taki K, Higashi T, Imamura Y, Ishimoto T, Iwatsuki M, Baba Y, Miyamoto Y, Yoshida N, Oki E, Watanabe M, Baba H. The Prognostic Significance of Histone Lysine Demethylase JMJD3/KDM6B in Colorectal Cancer. Ann Surg Oncol. 2016 Feb; 23(2):678-85. PMID: 26416711.
    View in: PubMed
  30. Murata A, Baba Y, Ishimoto T, Miyake K, Kosumi K, Harada K, Kurashige J, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Yamamoto M, Oda S, Watanabe M, Nakao M, Baba H. TET family proteins and 5-hydroxymethylcytosine in esophageal squamous cell carcinoma. Oncotarget. 2015 Sep 15; 6(27):23372-82. PMID: 26093090; PMCID: PMC4695124.
  31. Harada K, Baba Y, Ishimoto T, Kosumi K, Tokunaga R, Izumi D, Ohuchi M, Nakamura K, Kiyozumi Y, Kurashige J, Iwagami S, Miyamoto Y, Sakamoto Y, Yoshida N, Oki E, Watanabe M, Baba H. Suppressor microRNA-145 Is Epigenetically Regulated by Promoter Hypermethylation in Esophageal Squamous Cell Carcinoma. Anticancer Res. 2015 Sep; 35(9):4617-24. PMID: 26254350.
    View in: PubMed
  32. Higashi T, Hayashi H, Kaida T, Arima K, Takeyama H, Taki K, Izumi D, Tokunaga R, Kosumi K, Nakagawa S, Okabe H, Imai K, Nitta H, Hashimoto D, Chikamoto A, Beppu T, Baba H. Prognostic Impact of Visceral Fat Amount and Branched-Chain Amino Acids (BCAA) in Hepatocellular Carcinoma. Ann Surg Oncol. 2015 Dec; 22 Suppl 3:S1041-7. PMID: 26305023.
    View in: PubMed
  33. Kosumi K, Baba Y, Sakamoto A, Ishimoto T, Harada K, Nakamura K, Kurashige J, Hiyoshi Y, Iwatsuki M, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Oki E, Watanabe M, Hino S, Nakao M, Baba H. Lysine-specific demethylase-1 contributes to malignant behavior by regulation of invasive activity and metabolic shift in esophageal cancer. Int J Cancer. 2016 Jan 15; 138(2):428-39. PMID: 26240060.
    View in: PubMed
  34. Baba Y, Akiyama T, Kosumi K, Harada K, Shigaki H, Iwatsuki M, Sakamoto Y, Yoshida N, Watanabe M, Baba H. Esophageal Bypass Using a Y-Shaped Gastric Tube for Advanced Esophageal Cancer: Transabdominal Placement of the Decompression Tube. J Am Coll Surg. 2015 Nov; 221(5):e87-90. PMID: 26297480.
    View in: PubMed
  35. Harada K, Ida S, Baba Y, Ishimoto T, Kosumi K, Tokunaga R, Izumi D, Ohuchi M, Nakamura K, Kiyozumi Y, Imamura Y, Iwatsuki M, Iwagami S, Miyamoto Y, Sakamoto Y, Yoshida N, Watanabe M, Baba H. Prognostic and clinical impact of sarcopenia in esophageal squamous cell carcinoma. Dis Esophagus. 2016 Aug; 29(6):627-33. PMID: 26123787.
    View in: PubMed
  36. Kosumi K, Baba Y, Ishimoto T, Harada K, Nakamura K, Ohuchi M, Kiyozumi Y, Izumi D, Tokunaga R, Taki K, Higashi T, Miyata T, Kurashige J, Hiyoshi Y, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Watanabe M, Baba H. Neutrophil/lymphocyte ratio predicts the prognosis in esophageal squamous cell carcinoma patients. Surg Today. 2016 Apr; 46(4):405-13. PMID: 26036223.
    View in: PubMed
  37. Yoshida N, Baba Y, Oda E, Kosumi K, Ishimoto T, Watanabe M, Hiyoshi Y, Iwagami S, Kurashige J, Sakamoto Y, Miyamoto Y, Sugihara H, Eto K, Harada K, Baba H. Reconstruction Using a Pedunculated Gastric Tube with Duodenal Transection After Esophagectomy and Pharyngolaryngectomy. Ann Surg Oncol. 2015 Dec; 22(13):4352. PMID: 25786742.
    View in: PubMed
  38. Kosumi K, Baba Y, Ishimoto T, Harada K, Miyake K, Izumi D, Tokunaga R, Murata A, Eto K, Sugihara H, Shigaki H, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Watanabe M, Komohara Y, Takeya M, Baba H. Relationship between LINE-1 hypomethylation and Helicobacter pylori infection in gastric mucosae. Med Oncol. 2015 Apr; 32(4):117. PMID: 25782871.
    View in: PubMed
  39. Harada K, Baba Y, Ishimoto T, Kosumi K, Tokunaga R, Izumi D, Ida S, Imamura Y, Iwagami S, Miyamoto Y, Sakamoto Y, Yoshida N, Watanabe M, Baba H. Low Visceral Fat Content is Associated with Poor Prognosis in a Database of 507 Upper Gastrointestinal Cancers. Ann Surg Oncol. 2015 Nov; 22(12):3946-53. PMID: 25712800.
    View in: PubMed
  40. Baba Y, Ishimoto T, Harada K, Kosumi K, Murata A, Miyake K, Hiyoshi Y, Kurashige J, Iwatsuki M, Iwagami S, Miyamoto Y, Sakamoto Y, Yoshida N, Oki E, Iyama K, Watanabe M, Baba H. Molecular Characteristics of Basaloid Squamous Cell Carcinoma of the Esophagus: Analysis of KRAS, BRAF, and PIK3CA Mutations and LINE-1 Methylation. Ann Surg Oncol. 2015 Oct; 22(11):3659-65. PMID: 25691283.
    View in: PubMed
  41. Kosumi K, Takamori H, Hashimoto D, Tanaka H, Abe S, Nakahara O, Horino K, Baba H. Mucinous cystic neoplasm of the pancreas activated during pregnancy. Surg Case Rep. 2015 Dec; 1(1):13. PMID: 26943381; PMCID: PMC4747942.
  42. Harada K, Baba Y, Ishimoto T, Chikamoto A, Kosumi K, Hayashi H, Nitta H, Hashimoto D, Beppu T, Baba H. LINE-1 methylation level and patient prognosis in a database of 208 hepatocellular carcinomas. Ann Surg Oncol. 2015 Apr; 22(4):1280-7. PMID: 25319577.
    View in: PubMed
  43. Izumi D, Ishimoto T, Yoshida N, Nakamura K, Kosumi K, Tokunaga R, Sugihara H, Sawayama H, Karashima R, Imamura Y, Ida S, Hiyoshi Y, Iwagami S, Baba Y, Sakamoto Y, Miyamoto Y, Watanabe M, Baba H. A clinicopathological analysis of primary mucosal malignant melanoma. Surg Today. 2015 Jul; 45(7):886-91. PMID: 25297929.
    View in: PubMed
  44. Kosumi K, Baba Y, Watanabe M, Ida S, Nagai Y, Baba H. Pedunculated gastric conduit interposition with duodenal transection after salvage esophagectomy: an option for increasing the flexibility of the gastric conduit. J Am Coll Surg. 2012 May; 214(5):e31-3. PMID: 22445198.
    View in: PubMed
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