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Anne Trinh, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gil Del Alcazar CR, Trinh A, Aleckovic M, Rojas Jimenez E, Harper NW, Oliphant MUJ, Xie S, Krop ED, Lulseged B, Murphy KC, Keenan TE, Van Allen EM, Tolaney SM, Freeman GJ, Dillon DA, Muthuswamy SK, Polyak K. Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer. Cancer Immunol Res. 2022 06 03; 10(6):680-697. PMID: 35446942; PMCID: PMC9177779.
    Citations:    Fields:    Translation:HumansAnimals
  2. Ten Hoorn S, Waasdorp C, van Oijen MGH, Damhofer H, Trinh A, Zhao L, Smits LJH, Bootsma S, van Pelt GW, Mesker WE, Mol L, Goey KKH, Koopman M, Medema JP, Tuynman JB, Zlobec I, Punt CJA, Vermeulen L, Bijlsma MF. Serum-based measurements of stromal activation through ADAM12 associate with poor prognosis in colorectal cancer. BMC Cancer. 2022 Apr 12; 22(1):394. PMID: 35413826; PMCID: PMC9004139.
    Citations:    Fields:    Translation:HumansCells
  3. Trinh A, Khamari R, Fovez Q, Mahon FX, Turcq B, Bouscary D, Maboudou P, Joncquel M, Coiteux V, Germain N, Laine W, Dekiouk S, Jean-Pierre S, Maguer-Satta V, Ghesquiere B, Idziorek T, Quesnel B, Kluza J, Marchetti P. Antimetabolic cooperativity with the clinically approved l-asparaginase and tyrosine kinase inhibitors to eradicate CML stem cells. Mol Metab. 2022 01; 55:101410. PMID: 34863941; PMCID: PMC8732793.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Ten Hoorn S, Sommeijer DW, Elliott F, Fisher D, de Back TR, Trinh A, Koens L, Maughan T, Seligmann J, Seymour MT, Quirke P, Adams R, Richman SD, Punt CJA, Vermeulen L. Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. Br J Cancer. 2021 10; 125(8):1080-1088. PMID: 34253874; PMCID: PMC8505637.
    Citations:    Fields:    Translation:Humans
  5. Janiszewska M, Stein S, Metzger Filho O, Eng J, Kingston NL, Harper NW, Rye IH, Aleckovic M, Trinh A, Murphy KC, Marangoni E, Cristea S, Oakes B, Winer EP, Krop IE, Russnes HG, Spellman PT, Bucher E, Hu Z, Chin K, Gray JW, Michor F, Polyak K. The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer. JCI Insight. 2021 06 08; 6(11). PMID: 33886505; PMCID: PMC8262355.
    Citations: 6     Fields:    Translation:HumansCells
  6. Trinh A, Gil Del Alcazar CR, Shukla SA, Chin K, Chang YH, Thibault G, Eng J, Jovanovic B, Aldaz CM, Park SY, Jeong J, Wu C, Gray J, Polyak K. Genomic Alterations during the In Situ to Invasive Ductal Breast Carcinoma Transition Shaped by the Immune System. Mol Cancer Res. 2021 04; 19(4):623-635. PMID: 33443130; PMCID: PMC8026652.
    Citations: 4     Fields:    Translation:Humans
  7. Haasnoot KJC, Backes Y, Moons LMG, Kranenburg O, Trinh A, Vermeulen L, Noë M, Tuynman JB, van Lent AUG, van Ginneken R, Seldenrijk CA, Raicu MG, Trumpi K, Ubink I, Milne AN, Boonstra JJ, Groen JN, Schwartz MP, Wolfhagen FHJ, Geesing JMJ, Ter Borg F, Brosens LAA, van Bergeijk J, Spanier BWM, de Vos Tot Nederveen Cappel WH, Kessels K, Seerden TCJ, Vleggaar FP, Offerhaus GJA, Siersema PD, Elias SG, Laclé MM. Associations of non-pedunculated T1 colorectal adenocarcinoma outcome with consensus molecular subtypes, immunoscore, and microsatellite status: a multicenter case-cohort study. Mod Pathol. 2020 12; 33(12):2626-2636. PMID: 32581367.
    Citations: 5     Fields:    Translation:Humans
  8. Ge JY, Shu S, Kwon M, Jovanovic B, Murphy K, Gulvady A, Fassl A, Trinh A, Kuang Y, Heavey GA, Luoma A, Paweletz C, Thorner AR, Wucherpfennig KW, Qi J, Brown M, Sicinski P, McDonald TO, Pellman D, Michor F, Polyak K. Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer. Nat Commun. 2020 05 11; 11(1):2350. PMID: 32393766; PMCID: PMC7214447.
    Citations: 12     Fields:    Translation:AnimalsCells
  9. Trinh A, Polyak K. Tumor Neoantigens: When Too Much of a Good Thing Is Bad. Cancer Cell. 2019 11 11; 36(5):466-467. PMID: 31715129.
    Citations: 6     Fields:    Translation:Humans
  10. Peluffo G, Subedee A, Harper NW, Kingston N, Jovanovic B, Flores F, Stevens LE, Beca F, Trinh A, Chilamakuri CSR, Papachristou EK, Murphy K, Su Y, Marusyk A, D'Santos CS, Rueda OM, Beck AH, Caldas C, Carroll JS, Polyak K. EN1 Is a Transcriptional Dependency in Triple-Negative Breast Cancer Associated with Brain Metastasis. Cancer Res. 2019 08 15; 79(16):4173-4183. PMID: 31239270; PMCID: PMC6698222.
    Citations: 21     Fields:    Translation:HumansCells
  11. Trinh A, Lädrach C, Dawson HE, Ten Hoorn S, Kuppen PJK, Reimers MS, Koopman M, Punt CJA, Lugli A, Vermeulen L, Zlobec I. Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data. Br J Cancer. 2018 11; 119(10):1244-1251. PMID: 30385823; PMCID: PMC6251036.
    Citations: 22     Fields:    Translation:Humans
  12. Witwicki RM, Ekram MB, Qiu X, Janiszewska M, Shu S, Kwon M, Trinh A, Frias E, Ramadan N, Hoffman G, Yu K, Xie Y, McAllister G, McDonald R, Golji J, Schlabach M, deWeck A, Keen N, Chan HM, Ruddy D, Rejtar T, Sovath S, Silver S, Sellers WR, Jagani Z, Hogarty MD, Roberts C, Brown M, Stegmaier K, Long H, Shivdasani RA, Pellman D, Polyak K. TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer. Cell Rep. 2018 10 30; 25(5):1255-1267.e5. PMID: 30380416; PMCID: PMC6366939.
    Citations: 13     Fields:    Translation:HumansCells
  13. Rye IH, Trinh A, Saetersdal AB, Nebdal D, Lingjaerde OC, Almendro V, Polyak K, Børresen-Dale AL, Helland Å, Markowetz F, Russnes HG. Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors. Mol Oncol. 2018 11; 12(11):1838-1855. PMID: 30133130.
    Citations: 37     Fields:    Translation:Humans
  14. van der Waals LM, Jongen JMJ, Elias SG, Veremiyenko K, Trumpi K, Trinh A, Laoukili J, Ubink I, Schenning-van Schelven SJ, van Diest PJ, Borel Rinkes IHM, Kranenburg O. Increased Levels of Oxidative Damage in Liver Metastases Compared with Corresponding Primary Colorectal Tumors: Association with Molecular Subtype and Prior Treatment. Am J Pathol. 2018 10; 188(10):2369-2377. PMID: 30031728.
    Citations: 6     Fields:    Translation:Humans
  15. Marchetti P, Trinh A, Khamari R, Kluza J. Melanoma metabolism contributes to the cellular responses to MAPK/ERK pathway inhibitors. Biochim Biophys Acta Gen Subj. 2018 Apr; 1862(4):999-1005. PMID: 29413908.
    Citations: 21     Fields:    Translation:HumansCells
  16. Khamari R, Trinh A, Gabert PE, Corazao-Rozas P, Riveros-Cruz S, Balayssac S, Malet-Martino M, Dekiouk S, Joncquel Chevalier Curt M, Maboudou P, Garçon G, Ravasi L, Guerreschi P, Mortier L, Quesnel B, Marchetti P, Kluza J. Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors. Cell Death Dis. 2018 02 27; 9(3):325. PMID: 29487283.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  17. Ten Hoorn S, Trinh A, de Jong J, Koens L, Vermeulen L. Classification of Colorectal Cancer in Molecular Subtypes by Immunohistochemistry. Methods Mol Biol. 2018; 1765:179-191. PMID: 29589308.
    Citations: 16     Fields:    Translation:Humans
  18. Herath M, Wong P, Trinh A, Allan CA, Wallace EM, Ebeling PR, Fuller PJ, Milat F. Minimal-trauma ankle fractures predominate during pregnancy: a 17-year retrospective study. Arch Osteoporos. 2017 Sep 30; 12(1):86. PMID: 28965301.
    Citations:    Fields:    Translation:Humans
  19. Trinh A, Wong P, Sakthivel A, Fahey MC, Hennel S, Brown J, Strauss BJ, Ebeling PR, Fuller PJ, Milat F. Fat-Bone Interactions in Adults With Spina Bifida. J Endocr Soc. 2017 Oct 01; 1(10):1301-1311. PMID: 29264455; PMCID: PMC5686646.
    Citations: 1     
  20. Gil Del Alcazar CR, Huh SJ, Ekram MB, Trinh A, Liu LL, Beca F, Zi X, Kwak M, Bergholtz H, Su Y, Ding L, Russnes HG, Richardson AL, Babski K, Min Hui Kim E, McDonnell CH, Wagner J, Rowberry R, Freeman GJ, Dillon D, Sorlie T, Coussens LM, Garber JE, Fan R, Bobolis K, Allred DC, Jeong J, Park SY, Michor F, Polyak K. Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition. Cancer Discov. 2017 10; 7(10):1098-1115. PMID: 28652380; PMCID: PMC5628128.
    Citations: 86     Fields:    Translation:HumansCells
  21. Wang MT, Yao SH, Wong P, Trinh A, Ebeling PR, Tran T, Milat F, Mutalima N. Hip fractures in young adults: a retrospective cross-sectional study of characteristics, injury mechanism, risk factors, complications and follow-up. Arch Osteoporos. 2017 Dec; 12(1):46. PMID: 28474251.
    Citations: 7     Fields:    Translation:Humans
  22. André F, Trinh A, Balayssac S, Maboudou P, Dekiouk S, Malet-Martino M, Quesnel B, Idziorek T, Kluza J, Marchetti P. Metabolic rewiring in cancer cells overexpressing the glucocorticoid-induced leucine zipper protein (GILZ): Activation of mitochondrial oxidative phosphorylation and sensitization to oxidative cell death induced by mitochondrial targeted drugs. Int J Biochem Cell Biol. 2017 04; 85:166-174. PMID: 28259749.
    Citations: 4     Fields:    Translation:AnimalsCells
  23. Trinh A, Fahey MC, Brown J, Fuller PJ, Milat F. Optimizing bone health in cerebral palsy across the lifespan. Dev Med Child Neurol. 2017 02; 59(2):232-233. PMID: 28044317.
    Citations: 1     Fields:    Translation:Humans
  24. Marusyk A, Tabassum DP, Janiszewska M, Place AE, Trinh A, Rozhok AI, Pyne S, Guerriero JL, Shu S, Ekram M, Ishkin A, Cahill DP, Nikolsky Y, Chan TA, Rimawi MF, Hilsenbeck S, Schiff R, Osborne KC, Letai A, Polyak K. Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes. Cancer Res. 2016 11 15; 76(22):6495-6506. PMID: 27671678; PMCID: PMC5344673.
    Citations: 47     Fields:    Translation:HumansCells
  25. Piret SE, Gorvin CM, Trinh A, Taylor J, Lise S, Taylor JC, Ebeling PR, Thakker RV. Autosomal dominant osteopetrosis associated with renal tubular acidosis is due to a CLCN7 mutation. Am J Med Genet A. 2016 11; 170(11):2988-2992. PMID: 27540713.
    Citations: 3     Fields:    Translation:Humans
  26. Trinh A, Trumpi K, De Sousa E Melo F, Wang X, de Jong JH, Fessler E, Kuppen PJ, Reimers MS, Swets M, Koopman M, Nagtegaal ID, Jansen M, Hooijer GK, Offerhaus GJ, Kranenburg O, Punt CJ, Medema JP, Markowetz F, Vermeulen L. Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry. Clin Cancer Res. 2017 Jan 15; 23(2):387-398. PMID: 27459899.
    Citations: 69     Fields:    Translation:Humans
  27. Trinh A, Chan I, Alexiadis M, Pell M, Kumar B, Fuller PJ. Adrenal Cushing's syndrome in pregnancy: Clinical and molecular characterisation of a case. Obstet Med. 2016 Mar; 9(1):43-5. PMID: 27512490; PMCID: PMC4950436.
    Citations: 2     
  28. Saathoff H, Brofelth M, Trinh A, Parker BL, Ryan DP, Low JK, Webb SR, Silva AP, Mackay JP, Shepherd NE. A peptide affinity reagent for isolating an intact and catalytically active multi-protein complex from mammalian cells. Bioorg Med Chem. 2015 Mar 01; 23(5):960-5. PMID: 25678017.
    Citations: 5     Fields:    Translation:AnimalsCells
  29. Martins FC, Santiago Id, Trinh A, Xian J, Guo A, Sayal K, Jimenez-Linan M, Deen S, Driver K, Mack M, Aslop J, Pharoah PD, Markowetz F, Brenton JD. Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier. Genome Biol. 2014 Dec 17; 15(12):526. PMID: 25608477.
    Citations: 52     Fields:    Translation:HumansCells
  30. Trinh A, Rye IH, Almendro V, Helland A, Russnes HG, Markowetz F. GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images. Genome Biol. 2014 Aug 26; 15(8):442. PMID: 25168174.
    Citations: 8     Fields:    Translation:Humans
  31. Schwarz RF, Trinh A, Sipos B, Brenton JD, Goldman N, Markowetz F. Phylogenetic quantification of intra-tumour heterogeneity. PLoS Comput Biol. 2014 Apr; 10(4):e1003535. PMID: 24743184; PMCID: PMC3990475.
    Citations: 65     Fields:    Translation:Humans
  32. Tilburt JC, Koller K, Tiesinga JJ, Wilson RT, Trinh AC, Hill K, Hall IJ, Smith JL, Ekwueme DU, Petersen WO. Patterns of clinical response to PSA elevation in American Indian/Alaska Native men: a multi-center pilot study. J Health Care Poor Underserved. 2013 Nov; 24(4):1676-85. PMID: 24185163.
    Citations: 1     Fields:    Translation:Humans
  33. De Sousa E Melo F, Wang X, Jansen M, Fessler E, Trinh A, de Rooij LP, de Jong JH, de Boer OJ, van Leersum R, Bijlsma MF, Rodermond H, van der Heijden M, van Noesel CJ, Tuynman JB, Dekker E, Markowetz F, Medema JP, Vermeulen L. Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions. Nat Med. 2013 May; 19(5):614-8. PMID: 23584090.
    Citations: 347     Fields:    Translation:HumansCells
  34. Sadler GR, Lahousse SF, Riley J, Mercado B, Trinh AC, Cruz LA. Predictors of breast and cervical cancer screening among Chamorro women in Southern California. J Cancer Educ. 2010 Mar; 25(1):76-82. PMID: 20112139.
    Citations: 2     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.