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Shin-Ichiro Miyashita, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yin L, Masuyer G, Zhang S, Zhang J, Miyashita SI, Burgin D, Lovelock L, Coker SF, Fu TM, Stenmark P, Dong M. Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy. PLoS Biol. 2020 03; 18(3):e3000618. PMID: 32182233.
    Citations:    
  2. Miyashita SI, Sagane Y, Uchino T, Karatsu S, Hosoya K, Huang I, Niwa K, Watanabe T, Niimura Y, Suzuki T. Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes. Data Brief. 2019 Aug; 25:104193. PMID: 31321275.
    Citations:    
  3. Tao L, Tian S, Zhang J, Liu Z, Robinson-McCarthy L, Miyashita SI, Breault DT, Gerhard R, Oottamasathien S, Whelan SPJ, Dong M. Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells. Nat Microbiol. 2019 10; 4(10):1760-1769. PMID: 31160825.
    Citations:    
  4. Shen Y, Wu SY, Rancic V, Aggarwal A, Qian Y, Miyashita SI, Ballanyi K, Campbell RE, Dong M. Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration. Commun Biol. 2019 Jan 14; 2(1):18. PMID: 31924910.
    Citations:    
  5. Shen Y, Wu SY, Rancic V, Aggarwal A, Qian Y, Miyashita SI, Ballanyi K, Campbell RE, Dong M. Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration. Commun Biol. 2019; 2:18. PMID: 30652129.
    Citations:    
  6. Garland M, Babin BM, Miyashita SI, Loscher S, Shen Y, Dong M, Bogyo M. Covalent Modifiers of Botulinum Neurotoxin Counteract Toxin Persistence. ACS Chem Biol. 2019 01 18; 14(1):76-87. PMID: 30571080.
    Citations:    Fields:    
  7. Zhang S, Lebreton F, Mansfield MJ, Miyashita SI, Zhang J, Schwartzman JA, Tao L, Masuyer G, Martínez-Carranza M, Stenmark P, Gilmore MS, Doxey AC, Dong M. Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium. Cell Host Microbe. 2018 Feb 14; 23(2):169-176.e6. PMID: 29396040.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  8. Sagane Y, Mutoh S, Koizumi R, Suzuki T, Miyashita SI, Miyata K, Ohyama T, Niwa K, Watanabe T. Reversible Association of the Hemagglutinin Subcomplex, HA-33/HA-17 Trimer, with the Botulinum Toxin Complex. Protein J. 2017 10; 36(5):417-424. PMID: 28707196.
    Citations:    Fields:    Translation:Cells
  9. Chevalier A, Silva DA, Rocklin GJ, Hicks DR, Vergara R, Murapa P, Bernard SM, Zhang L, Lam KH, Yao G, Bahl CD, Miyashita SI, Goreshnik I, Fuller JT, Koday MT, Jenkins CM, Colvin T, Carter L, Bohn A, Bryan CM, Fernández-Velasco DA, Stewart L, Dong M, Huang X, Jin R, Wilson IA, Fuller DH, Baker D. Massively parallel de novo protein design for targeted therapeutics. Nature. 2017 10 05; 550(7674):74-79. PMID: 28953867.
    Citations: 16     Fields:    Translation:HumansCells
  10. Zhang S, Masuyer G, Zhang J, Shen Y, Lundin D, Henriksson L, Miyashita SI, Martínez-Carranza M, Dong M, Stenmark P. Identification and characterization of a novel botulinum neurotoxin. Nat Commun. 2017 08 03; 8:14130. PMID: 28770820.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  11. Miyashita S, Sagane Y, Suzuki T, Matsumoto T, Niwa K, Watanabe T. "Non-Toxic" Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity. Sci Rep. 2016 08 10; 6:31043. PMID: 27507612.
    Citations: 2     Fields:    Translation:AnimalsCells
  12. Miyata K, Suzuki T, Hayashi S, Miyashita S, Ohyama T, Niwa K, Watanabe T, Sagane Y. Hemagglutinin gene shuffling among Clostridium botulinum serotypes C and D yields distinct sugar recognition of the botulinum toxin complex. Pathog Dis. 2015 Oct; 73(7). PMID: 26223883.
    Citations: 2     Fields:    Translation:AnimalsCells
  13. Miyashita S, Niwa K, Watanabe T, Sagane Y. Host-cell specificity and transcytosis of nontoxic nonhemagglutinin protein of botulinum neurotoxin serotype D. FEMS Microbiol Lett. 2014 Aug; 357(2):115-22. PMID: 25041523.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  14. Suzuki T, Miyashita S, Hayashi S, Miyata K, Inui K, Kondo Y, Miyazaki S, Ohyama T, Niwa K, Watanabe T, Sagane Y. Identification of the interaction region between hemagglutinin components of the botulinum toxin complex. Int J Biol Macromol. 2014 Apr; 65:284-8. PMID: 24472509.
    Citations:    Fields:    Translation:Cells
  15. Miyashita S, Sagane Y, Inui K, Hayashi S, Miyata K, Suzuki T, Ohyama T, Watanabe T, Niwa K. Botulinum toxin complex increases paracellular permeability in intestinal epithelial cells via activation of p38 mitogen-activated protein kinase. J Vet Med Sci. 2013 Dec 30; 75(12):1637-42. PMID: 23884081.
    Citations: 1     Fields:    Translation:AnimalsCells
  16. Miyashita S, Sagane Y, Niwa K, Watanabe T. Transport of the botulinum neurotoxin-associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer. FEMS Microbiol Lett. 2013 Sep; 346(1):73-80. PMID: 23809018.
    Citations: 1     Fields:    Translation:AnimalsCells
  17. Sagane Y, Miyata K, Kurihara S, Yoneyama T, Inui K, Miyashita S, Hayashi S, Suzuki T, Niwa K, Watanabe T. Random phage display-based screening of peptides that bind to botulinum neurotoxin binding protein, nontoxic nonhemagglutinin. Curr Microbiol. 2013 Aug; 67(2):188-92. PMID: 23503763.
    Citations:    
  18. Miyata K, Sagane Y, Inui K, Miyashita S, Suzuki T, Oguma K, Ohyama T, Niwa K, Watanabe T. Purification and characterization of nontoxic protein complex from serotype D 4947 botulinum toxin complex. Protein J. 2012 Jun; 31(5):387-92. PMID: 22565346.
    Citations: 1     Fields:    Translation:AnimalsCells
  19. Inui K, Sagane Y, Miyata K, Miyashita S, Suzuki T, Shikamori Y, Ohyama T, Niwa K, Watanabe T. Toxic and nontoxic components of botulinum neurotoxin complex are evolved from a common ancestral zinc protein. Biochem Biophys Res Commun. 2012 Mar 16; 419(3):500-4. PMID: 22366035.
    Citations:    Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.