Harvard Catalyst Profiles

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Marcela Valderrama Maus, M.D., Ph.D.

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Mentoring
Characterization of Dexamethasone Suppression of Chimeric Antigen Receptor (CAR) T Cells Targeting Glioblastoma Multiforme
Full Time/Year Long, 09/01/17 - 06/30/18
Targeting Tumor Heterogeneity in the Treatment of Glioblastoma Multiforme (GBM) Using BiTE-Secreting EGFRvIII CAR T-cells
Soma Weiss, 09/01/17 - 03/30/19

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. UG3CA283619 (MAUS, MARCELA VALDERRAMA) Aug 9, 2023 - Jul 31, 2025
    NIH
    CAR T cells targeting mesothelin and secreting bispecific antibodies targeting fibroblasts in pancreatic cancer
    Role: Principal Investigator
  2. R01CA249062 (MAUS, MARCELA VALDERRAMA) Jan 7, 2021 - Dec 31, 2025
    NIH
    Understanding and manipulating programmed cell death (PCD) pathways to facilitate lymphoid tumor killing by CAR T cells
    Role: Principal Investigator
  3. R01CA252940 (MAUS, MARCELA VALDERRAMA) Sep 1, 2020 - May 31, 2025
    NIH
    Efficacy and immune effects of anakinra prophylaxis for neurologic toxicity and cytokine release syndrome in patients with lymphoma receiving axicabtagene ciloleucel
    Role: Principal Investigator
  4. R01CA238268 (MAUS, MARCELA VALDERRAMA) Sep 20, 2019 - Aug 31, 2024
    NIH
    Overcoming tumor heterogeneity in glioblastoma with multi-targeted CAR T cells secreting bispecific antibodies
    Role: Principal Investigator
  5. K08CA166039 (MAUS, MARCELA VALDERRAMA) Sep 19, 2012 - Aug 31, 2017
    NIH
    Designer antigen receptors to re-direct T cells to the NY-ESO-1 tumor antigen
    Role: Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.