Harvard Catalyst Profiles

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Evan Michael Appleton, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chao G, Wannier TM, Gutierrez C, Borders NC, Appleton E, Chadha A, Lebar T, Church GM. helixCAM: A platform for programmable cellular assembly in bacteria and human cells. Cell. 2022 Sep 15; 185(19):3551-3567.e39. PMID: 36055250; PMCID: PMC9481732.
    Citations:    Fields:    Translation:HumansCells
  2. Tian S, Liu Y, Appleton E, Wang H, Church GM, Dong M. Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms. Cell Rep. 2022 03 08; 38(10):110476. PMID: 35263584; PMCID: PMC8958846.
    Citations:    Fields:    Translation:HumansCells
  3. Zaki MM, Lesha E, Said K, Kiaee K, Robinson-McCarthy L, George H, Hanna A, Appleton E, Liu S, Ng AHM, Khoshakhlagh P, Church GM. Cell therapy strategies for COVID-19: Current approaches and potential applications. Sci Adv. 2021 Aug; 7(33). PMID: 34380619.
    Citations: 4     Fields:    
  4. Kunjapur AM, Napolitano MG, Hysolli E, Noguera K, Appleton EM, Schubert MG, Jones MA, Iyer S, Mandell DJ, Church GM. Synthetic auxotrophy remains stable after continuous evolution and in coculture with mammalian cells. Sci Adv. 2021 Jul; 7(27). PMID: 34215581.
    Citations: 3     Fields:    
  5. Jung S, Appleton E, Ali M, Church GM, Del Sol A. A computer-guided design tool to increase the efficiency of cellular conversions. Nat Commun. 2021 03 12; 12(1):1659. PMID: 33712564.
    Citations: 5     Fields:    Translation:HumansCells
  6. Vaidyanathan P, Appleton E, Tran D, Vahid A, Church G, Densmore D. Algorithms for the selection of fluorescent reporters. Commun Biol. 2021 01 26; 4(1):118. PMID: 33500520.
    Citations:    
  7. Ng AHM, Khoshakhlagh P, Rojo Arias JE, Pasquini G, Wang K, Swiersy A, Shipman SL, Appleton E, Kiaee K, Kohman RE, Vernet A, Dysart M, Leeper K, Saylor W, Huang JY, Graveline A, Taipale J, Hill DE, Vidal M, Melero-Martin JM, Busskamp V, Church GM. A comprehensive library of human transcription factors for cell fate engineering. Nat Biotechnol. 2021 04; 39(4):510-519. PMID: 33257861; PMCID: PMC7610615.
    Citations: 27     Fields:    Translation:HumansCells
  8. Appleton E, Densmore D, Madsen C, Roehner N. Needs and opportunities in bio-design automation: four areas for focus. Curr Opin Chem Biol. 2017 Oct; 40:111-118. PMID: 28923279.
    Citations: 7     Fields:    Translation:HumansAnimals
  9. Appleton E, Madsen C, Roehner N, Densmore D. Design Automation in Synthetic Biology. Cold Spring Harb Perspect Biol. 2017 Apr 03; 9(4). PMID: 28246188; PMCID: PMC5378053.
    Citations: 16     Fields:    
  10. Appleton E, Tao J, Wheatley FC, Desai DH, Lozanoski TM, Shah PD, Awtry JA, Jin SS, Haddock TL, Densmore DM. Owl: electronic datasheet generator. ACS Synth Biol. 2014 Dec 19; 3(12):966-8. PMID: 25524100.
    Citations: 1     Fields:    
  11. Oye KA, Esvelt K, Appleton E, Catteruccia F, Church G, Kuiken T, Lightfoot SB, McNamara J, Smidler A, Collins JP. Biotechnology. Regulating gene drives. Science. 2014 Aug 08; 345(6197):626-8. PMID: 25035410.
    Citations: 103     Fields:    Translation:HumansAnimalsPHPublic Health
  12. Appleton E, Tao J, Haddock T, Densmore D. Interactive assembly algorithms for molecular cloning. Nat Methods. 2014 Jun; 11(6):657-62. PMID: 24776633.
    Citations: 18     Fields:    
  13. Beal J, Weiss R, Densmore D, Adler A, Appleton E, Babb J, Bhatia S, Davidsohn N, Haddock T, Loyall J, Schantz R, Vasilev V, Yaman F. An end-to-end workflow for engineering of biological networks from high-level specifications. ACS Synth Biol. 2012 Aug 17; 1(8):317-31. PMID: 23651286.
    Citations: 18     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.