Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Jennifer En-Sian Ho, M.D.

Title
Institution
Department
Address

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K24HL153669 (HO, JENNIFER EN-SIAN) Jul 1, 2020 - Jun 30, 2025
    NIH
    Mentoring in Patient-Oriented and Translational HFpEF Research
    Role: Principal Investigator
  2. R01HL140224 (HO, JENNIFER EN-SIAN) Dec 15, 2017 - Nov 30, 2021
    NIH
    Eicosanoid Profiles as Determinants of HFpEF
    Role: Principal Investigator
  3. R01HL134893 (HO, JENNIFER EN-SIAN) Jul 1, 2017 - Jun 30, 2022
    NIH
    The Association of Metabolic Disease and Pulmonary Hypertension
    Role: Principal Investigator
  4. K23HL116780 (HO, JENNIFER EN-SIAN) Apr 1, 2013 - Dec 1, 2015
    NIH
    The Role of Galectin-3 in Cardiac Remodeling and Heart Failure
    Role: Principal Investigator
  5. F32HL095424 (HO, JENNIFER EN-SIAN) Mar 1, 2009 - Jun 30, 2009
    NIH
    The Role of Endothelias Dysfunction in HIV-Associated Pulmonary Hypertension
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zern EK, Ho JE, Panah LG, Lau ES, Liu E, Farrell R, Sbarbaro JA, Schoenike MW, Pappagianopoulos PP, Namasivayam M, Malhotra R, Nayor M, Lewis GD. Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Arterial Stiffness and Aabnormal Left Ventricular Hemodynamic Responses During Exercise. J Card Fail. 2021 Feb 26. PMID: 33647476.
    Citations:    Fields:    
  2. Churchill TW, Li SX, Curreri L, Zern EK, Lau ES, Liu EE, Farrell R, Shoenike MW, Sbarbaro J, Malhotra R, Nayor M, Tschöpe C, de Boer RA, Lewis GD, Ho JE. Evaluation of 2 Existing Diagnostic Scores for Heart Failure With Preserved Ejection Fraction Against a Comprehensively Phenotyped Cohort. Circulation. 2021 Jan 19; 143(3):289-291. PMID: 33464963.
    Citations:    Fields:    
  3. Lau ES, Liu E, Paniagua SM, Sarma AA, Zampierollo G, López B, Díez J, Wang TJ, Ho JE. Galectin-3 Inhibition With Modified Citrus Pectin in Hypertension. JACC Basic Transl Sci. 2021 Jan; 6(1):12-21. PMID: 33532663.
    Citations:    
  4. McNeill JN, Lau ES, Paniagua SM, Liu EE, Wang JK, Bassett IV, Selvaggi CA, Lubitz SA, Foulkes AS, Ho JE. The role of obesity in inflammatory markers in COVID-19 patients. Obes Res Clin Pract. 2021 Jan-Feb; 15(1):96-99. PMID: 33390322.
    Citations:    Fields:    Translation:Humans
  5. Ho JE, Redfield MM, Lewis GD, Paulus WJ, Lam CSP. Deliberating the Diagnostic Dilemma of Heart Failure With Preserved Ejection Fraction. Circulation. 2020 Nov 03; 142(18):1770-1780. PMID: 33136513.
    Citations: 1     Fields:    
  6. Suthahar N, Lau ES, Blaha MJ, Paniagua SM, Larson MG, Psaty BM, Benjamin EJ, Allison MA, Bartz TM, Januzzi JL, Levy D, Meems LMG, Bakker SJL, Lima JAC, Cushman M, Lee DS, Wang TJ, deFilippi CR, Herrington DM, Nayor M, Vasan RS, Gardin JM, Kizer JR, Bertoni AG, Allen NB, Gansevoort RT, Shah SJ, Gottdiener JS, Ho JE, de Boer RA. Sex-Specific Associations of Cardiovascular Risk Factors and Biomarkers With Incident Heart Failure. J Am Coll Cardiol. 2020 09 22; 76(12):1455-1465. PMID: 32943164.
    Citations: 2     Fields:    Translation:Humans
  7. Nayor M, Shah RV, Miller PE, Blodgett JB, Tanguay M, Pico AR, Murthy VL, Malhotra R, Houstis NE, Deik A, Pierce KA, Bullock K, Dailey L, Velagaleti RS, Moore SA, Ho JE, Baggish AL, Clish CB, Larson MG, Vasan RS, Lewis GD. Metabolic Architecture of Acute Exercise Response in Middle-Aged Adults in the Community. Circulation. 2020 Nov 17; 142(20):1905-1924. PMID: 32927962.
    Citations: 3     Fields:    
  8. Ho JE. Aldosterone Antagonism in Atrial Fibrillation: Implications for AF-Predominant HFpEF. J Am Heart Assoc. 2020 09 15; 9(18):e018396. PMID: 32909522.
    Citations: 1     Fields:    Translation:Humans
  9. Nayor M, Houstis NE, Namasivayam M, Rouvina J, Hardin C, Shah RV, Ho JE, Malhotra R, Lewis GD. Impaired Exercise Tolerance in Heart Failure With Preserved Ejection Fraction: Quantification of Multiorgan System Reserve Capacity. JACC Heart Fail. 2020 08; 8(8):605-617. PMID: 32535122.
    Citations: 2     Fields:    
  10. Al-Khatib SM, Benjamin EJ, Albert CM, Alonso A, Chauhan C, Chen PS, Curtis AB, Desvigne-Nickens P, Ho JE, Lam CSP, Link MS, Patton KK, Redfield MM, Rienstra M, Rosenberg Y, Schnabel R, Spertus JA, Stevenson LW, Hills MT, Voors AA, Cooper LS, Go AS. Advancing Research on the Complex Interrelations Between Atrial Fibrillation and Heart Failure: A Report From a US National Heart, Lung, and Blood Institute Virtual Workshop. Circulation. 2020 Jun 09; 141(23):1915-1926. PMID: 32511001.
    Citations: 2     Fields:    
  11. Narayan V, Thompson EW, Demissei B, Ho JE, Januzzi JL, Ky B. Mechanistic Biomarkers Informative of Both Cancer and Cardiovascular Disease: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020 06 02; 75(21):2726-2737. PMID: 32466889.
    Citations:    Fields:    Translation:Humans
  12. Ho JE, Lewis GD. Reply: Does PAP/CO Ratio Have a Linear Relationship? J Am Coll Cardiol. 2020 05 26; 75(20):2647. PMID: 32439017.
    Citations:    Fields:    Translation:Humans
  13. Nayor M, Xanthakis V, Tanguay M, Blodgett JB, Shah RV, Schoenike M, Sbarbaro J, Farrell R, Malhotra R, Houstis NE, Velagaleti RS, Moore SA, Baggish AL, O'Connor GT, Ho JE, Larson MG, Vasan RS, Lewis GD. Clinical and Hemodynamic Associations and Prognostic Implications of Ventilatory Efficiency in Patients With Preserved Left Ventricular Systolic Function. Circ Heart Fail. 2020 05; 13(5):e006729. PMID: 32362167.
    Citations:    Fields:    Translation:Humans
  14. Zanni MV, Awadalla M, Toribio M, Robinson J, Stone LA, Cagliero D, Rokicki A, Mulligan CP, Ho JE, Neilan AM, Siedner MJ, Triant VA, Stanley TL, Szczepaniak LS, Jerosch-Herold M, Nelson MD, Burdo TH, Neilan TG. Immune Correlates of Diffuse Myocardial Fibrosis and Diastolic Dysfunction Among Aging Women With Human Immunodeficiency Virus. J Infect Dis. 2020 03 28; 221(8):1315-1320. PMID: 31100122.
    Citations: 9     Fields:    Translation:HumansCells
  15. Suthahar N, Meems LMG, Ho JE, de Boer RA. Sex-related differences in contemporary biomarkers for heart failure: a review. Eur J Heart Fail. 2020 05; 22(5):775-788. PMID: 32220046.
    Citations: 4     Fields:    
  16. Frank RC, Min J, Abdelghany M, Paniagua S, Bhattacharya R, Bhambhani V, Pomerantsev E, Ho JE. Obesity Is Associated With Pulmonary Hypertension and Modifies Outcomes. J Am Heart Assoc. 2020 03 03; 9(5):e014195. PMID: 32079475.
    Citations: 2     Fields:    Translation:Humans
  17. Ho JE, Zern EK, Lau ES, Wooster L, Bailey CS, Cunningham T, Eisman AS, Hardin KM, Farrell R, Sbarbaro JA, Schoenike MW, Houstis NE, Baggish AL, Shah RV, Nayor M, Malhotra R, Lewis GD. Exercise Pulmonary Hypertension Predicts Clinical Outcomes in Patients With Dyspnea on Effort. J Am Coll Cardiol. 2020 01 07; 75(1):17-26. PMID: 31918830.
    Citations: 5     Fields:    Translation:Humans
  18. Lau ES, Cunningham T, Hardin KM, Liu E, Malhotra R, Nayor M, Lewis GD, Ho JE. Sex Differences in Cardiometabolic Traits and Determinants of Exercise Capacity in Heart Failure With Preserved Ejection Fraction. JAMA Cardiol. 2020 01 01; 5(1):30-37. PMID: 31664435.
    Citations: 3     Fields:    Translation:Humans
  19. Toribio M, Neilan TG, Awadalla M, Stone LA, Rokicki A, Rivard C, Mulligan CP, Cagliero D, Fourman LT, Stanley TL, Ho JE, Triant VA, Burdo TH, Nelson MD, Szczepaniak LS, Zanni MV. Intramyocardial Triglycerides Among Women With vs Without HIV: Hormonal Correlates and Functional Consequences. J Clin Endocrinol Metab. 2019 12 01; 104(12):6090-6100. PMID: 31393564.
    Citations: 4     Fields:    Translation:HumansCells
  20. Gómez-Banoy N, Guseh JS, Li G, Rubio-Navarro A, Chen T, Poirier B, Putzel G, Rosselot C, Pabón MA, Camporez JP, Bhambhani V, Hwang SJ, Yao C, Perry RJ, Mukherjee S, Larson MG, Levy D, Dow LE, Shulman GI, Dephoure N, Garcia-Ocana A, Hao M, Spiegelman BM, Ho JE, Lo JC. Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans. Nat Med. 2019 11; 25(11):1739-1747. PMID: 31700183.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  21. Lau ES, Paniagua SM, Guseh JS, Bhambhani V, Zanni MV, Courchesne P, Lyass A, Larson MG, Levy D, Ho JE. Sex Differences in Circulating Biomarkers of Cardiovascular Disease. J Am Coll Cardiol. 2019 09 24; 74(12):1543-1553. PMID: 31537263.
    Citations: 11     Fields:    Translation:Humans
  22. Bethea ED, Gaj K, Gustafson JL, Axtell A, Lebeis T, Schoenike M, Turvey K, Coglianese E, Thomas S, Newton-Cheh C, Ibrahim N, Carlson W, Ho JE, Shah R, Nayor M, Gift T, Shao S, Dugal A, Markmann J, Elias N, Yeh H, Andersson K, Pratt D, Bhan I, Safa K, Fishman J, Kotton C, Myoung P, Villavicencio MA, D'Alessandro D, Chung RT, Lewis GD. Pre-emptive pangenotypic direct acting antiviral therapy in donor HCV-positive to recipient HCV-negative heart transplantation: an open-label study. Lancet Gastroenterol Hepatol. 2019 10; 4(10):771-780. PMID: 31353243.
    Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
  23. Ho JE, Zern EK, Wooster L, Bailey CS, Cunningham T, Eisman AS, Hardin KM, Zampierollo GA, Jarolim P, Pappagianopoulos PP, Malhotra R, Nayor M, Lewis GD. Differential Clinical Profiles, Exercise Responses, and Outcomes Associated With Existing HFpEF Definitions. Circulation. 2019 07 30; 140(5):353-365. PMID: 31132875.
    Citations: 11     Fields:    Translation:Humans
  24. Ghorbani A, Ho JE. Reply: Galectin-3: A Pathophysiological Background Index or an Emerging Prognostic Biomarker in Heart Failure? J Am Coll Cardiol. 2019 04 16; 73(14):1875-1876. PMID: 30975312.
    Citations:    Fields:    Translation:Humans
  25. Gopal DM, Ayalon N, Wang YC, Siwik D, Sverdlov A, Donohue C, Perez A, Downing J, Apovian C, Silva V, Panagia M, Kolachalama V, Ho JE, Liang CS, Gokce N, Colucci WS. Galectin-3 Is Associated With Stage B Metabolic Heart Disease and Pulmonary Hypertension in Young Obese Patients. J Am Heart Assoc. 2019 04 02; 8(7):e011100. PMID: 30929550.
    Citations: 8     Fields:    Translation:Humans
  26. Ghorbani A, Bhambhani V, Christenson RH, Meijers WC, de Boer RA, Levy D, Larson MG, Ho JE. Longitudinal Change in Galectin-3 and Incident Cardiovascular Outcomes. J Am Coll Cardiol. 2018 12 25; 72(25):3246-3254. PMID: 30573026.
    Citations: 11     Fields:    Translation:Humans
  27. Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D. Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nat Commun. 2018 09 18; 9(1):3853. PMID: 30228274.
    Citations: 1     Fields:    
  28. de Boer RA, Nayor M, Ho JE. High-Sensitivity Troponin and Heart Failure With Preserved Ejection Fraction-Balancing P Values With Prior Knowledge and Common Sense-Reply. JAMA Cardiol. 2018 09 01; 3(9):892-893. PMID: 29926109.
    Citations:    Fields:    Translation:Humans
  29. Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D. Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nat Commun. 2018 08 15; 9(1):3268. PMID: 30111768.
    Citations: 37     Fields:    Translation:HumansCells
  30. Foldyna B, Fourman LT, Lu MT, Mueller ME, Szilveszter B, Neilan TG, Ho JE, Burdo TH, Lau ES, Stone LA, Toribio M, Srinivasa S, Looby SE, Lo J, Fitch KV, Zanni MV. Sex Differences in Subclinical Coronary Atherosclerotic Plaque Among Individuals With HIV on Antiretroviral Therapy. . 2018 08 01; 78(4):421-428. PMID: 29601406.
    Citations: 4     Translation:Humans
  31. Ho JE, Lyass A, Courchesne P, Chen G, Liu C, Yin X, Hwang SJ, Massaro JM, Larson MG, Levy D. Protein Biomarkers of Cardiovascular Disease and Mortality in the Community. J Am Heart Assoc. 2018 07 13; 7(14). PMID: 30006491.
    Citations: 36     Fields:    Translation:Humans
  32. Tsao CW, Lyass A, Enserro D, Larson MG, Ho JE, Kizer JR, Gottdiener JS, Psaty BM, Vasan RS. Temporal Trends in the Incidence of and Mortality Associated With Heart Failure With Preserved and Reduced Ejection Fraction. JACC Heart Fail. 2018 08; 6(8):678-685. PMID: 30007560.
    Citations: 24     Fields:    Translation:Humans
  33. Savji N, Meijers WC, Bartz TM, Bhambhani V, Cushman M, Nayor M, Kizer JR, Sarma A, Blaha MJ, Gansevoort RT, Gardin JM, Hillege HL, Ji F, Kop WJ, Lau ES, Lee DS, Sadreyev R, van Gilst WH, Wang TJ, Zanni MV, Vasan RS, Allen NB, Psaty BM, van der Harst P, Levy D, Larson M, Shah SJ, de Boer RA, Gottdiener JS, Ho JE. The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF. JACC Heart Fail. 2018 08; 6(8):701-709. PMID: 30007554.
    Citations: 38     Fields:    Translation:Humans
  34. Ho JE. ß-Blockers After Inotropes in Acute Heart Failure-When Is the Right Time? Can J Cardiol. 2018 09; 34(9):1102-1103. PMID: 30033081.
    Citations:    Fields:    Translation:Humans
  35. Suthahar N, Meijers WC, Ho JE, Gansevoort RT, Voors AA, van der Meer P, Bakker SJL, Heymans S, van Empel V, Schroen B, van der Harst P, van Veldhuisen DJ, de Boer RA. Sex-specific associations of obesity and N-terminal pro-B-type natriuretic peptide levels in the general population. Eur J Heart Fail. 2018 08; 20(8):1205-1214. PMID: 29855124.
    Citations: 13     Fields:    Translation:HumansPHPublic Health
  36. Eisman AS, Shah RV, Dhakal BP, Pappagianopoulos PP, Wooster L, Bailey C, Cunningham TF, Hardin KM, Baggish AL, Ho JE, Malhotra R, Lewis GD. Pulmonary Capillary Wedge Pressure Patterns During Exercise Predict Exercise Capacity and Incident Heart Failure. Circ Heart Fail. 2018 05; 11(5):e004750. PMID: 29695381.
    Citations: 19     Fields:    Translation:Humans
  37. Jiang J, Thalamuthu A, Ho JE, Mahajan A, Ek WE, Brown DA, Breit SN, Wang TJ, Gyllensten U, Chen MH, Enroth S, Januzzi JL, Lind L, Armstrong NJ, Kwok JB, Schofield PR, Wen W, Trollor JN, Johansson Å, Morris AP, Vasan RS, Sachdev PS, Mather KA. A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood. Front Genet. 2018; 9:97. PMID: 29628937.
    Citations: 5     
  38. de Boer RA, Nayor M, deFilippi CR, Enserro D, Bhambhani V, Kizer JR, Blaha MJ, Brouwers FP, Cushman M, Lima JAC, Bahrami H, van der Harst P, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Shah SJ, Levy D, Herrington DM, Larson MG, van Gilst WH, Gottdiener JS, Bertoni AG, Ho JE. Association of Cardiovascular Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction. JAMA Cardiol. 2018 03 01; 3(3):215-224. PMID: 29322198.
    Citations: 37     Fields:    Translation:Humans
  39. Suthahar N, Meijers WC, Silljé HHW, Ho JE, Liu FT, de Boer RA. Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An Update. Theranostics. 2018; 8(3):593-609. PMID: 29344292.
    Citations: 31     Fields:    Translation:HumansAnimals
  40. Bhambhani V, Kizer JR, Lima JAC, van der Harst P, Bahrami H, Nayor M, de Filippi CR, Enserro D, Blaha MJ, Cushman M, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Brouwers FP, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Levy D, Herrington DM, van Gilst WH, Bertoni AG, Larson MG, de Boer RA, Gottdiener JS, Shah SJ, Ho JE. Predictors and outcomes of heart failure with mid-range ejection fraction. Eur J Heart Fail. 2018 04; 20(4):651-659. PMID: 29226491.
    Citations: 16     Fields:    Translation:Humans
  41. Ho JE. Harnessing the Power of Pharmacometabolomics: The Metabolic Footprint of Statins. Circ Cardiovasc Genet. 2017 12; 10(6). PMID: 29237684.
    Citations:    Fields:    
  42. Ho JE, Shi L, Day SM, Colan SD, Russell MW, Towbin JA, Sherrid MV, Canter CE, Jefferies JL, Murphy A, Taylor M, Mestroni L, Cirino AL, Sleeper LA, Jarolim P, Lopez B, Gonzalez A, Diez J, Orav EJ, Ho CY. Biomarkers of cardiovascular stress and fibrosis in preclinical hypertrophic cardiomyopathy. Open Heart. 2017; 4(2):e000615. PMID: 29177058.
    Citations: 7     
  43. Ho JE. High-Sensitivity Troponin in the General Population: Time for a New Normal? J Am Coll Cardiol. 2017 08 01; 70(5):569-571. PMID: 28750700.
    Citations:    Fields:    Translation:Humans
  44. Ho JE, Rahban Y, Sandhu H, Hiremath PG, Ayalon N, Qin F, Perez AJ, Downing J, Gopal DM, Cheng S, Colucci WS. Preclinical Alterations in Myocardial Microstructure in People with Metabolic Syndrome. Obesity (Silver Spring). 2017 09; 25(9):1516-1522. PMID: 28737258.
    Citations: 2     Fields:    Translation:Humans
  45. Ho JE. Can Heart Failure With Preserved Ejection Fraction Shed Light on the Mortality-Readmissions Paradox? JACC Heart Fail. 2017 07; 5(7):494-496. PMID: 28501520.
    Citations:    Fields:    Translation:Humans
  46. Ho JE, McCabe EL, Wang TJ, Larson MG, Levy D, Tsao C, Aragam J, Mitchell GF, Benjamin EJ, Vasan RS, Cheng S. Cardiometabolic Traits and Systolic Mechanics in the Community. Circ Heart Fail. 2017 May; 10(5). PMID: 28495953.
    Citations: 8     Fields:    Translation:Humans
  47. Nayor M, Larson MG, Wang N, Santhanakrishnan R, Lee DS, Tsao CW, Cheng S, Benjamin EJ, Vasan RS, Levy D, Fox CS, Ho JE. The association of chronic kidney disease and microalbuminuria with heart failure with preserved vs. reduced ejection fraction. Eur J Heart Fail. 2017 05; 19(5):615-623. PMID: 28217978.
    Citations: 8     Fields:    Translation:Humans
  48. Meijers WC, de Boer RA, Ho JE. Biomarkers to identify and prevent new-onset heart failure in the community. Eur J Heart Fail. 2016 11; 18(11):1351-1352. PMID: 27813301.
    Citations: 1     Fields:    Translation:Humans
  49. Hiremath P, Lawler PR, Ho JE, Correia AW, Abbasi SA, Kwong RY, Jerosch-Herold M, Ho CY, Cheng S. Ultrasonic Assessment of Myocardial Microstructure in Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers With and Without Left Ventricular Hypertrophy. Circ Heart Fail. 2016 09; 9(9). PMID: 27623770.
    Citations: 3     Fields:    Translation:Humans
  50. Rhee EP, Yang Q, Yu B, Liu X, Cheng S, Deik A, Pierce KA, Bullock K, Ho JE, Levy D, Florez JC, Kathiresan S, Larson MG, Vasan RS, Clish CB, Wang TJ, Boerwinkle E, O'Donnell CJ, Gerszten RE. An exome array study of the plasma metabolome. Nat Commun. 2016 07 25; 7:12360. PMID: 27453504.
    Citations: 26     Fields:    Translation:Humans
  51. Ho JE, Gao W, Levy D, Santhanakrishnan R, Araki T, Rosas IO, Hatabu H, Latourelle JC, Nishino M, Dupuis J, Washko GR, O'Connor GT, Hunninghake GM. Galectin-3 Is Associated with Restrictive Lung Disease and Interstitial Lung Abnormalities. Am J Respir Crit Care Med. 2016 07 01; 194(1):77-83. PMID: 26771117.
    Citations: 13     Fields:    Translation:Humans
  52. Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Response to Letter Regarding Article, "Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction". Circulation. 2016 Jun 07; 133(23):e692-3. PMID: 27267541.
    Citations:    Fields:    Translation:Humans
  53. Ho JE, Enserro D, Brouwers FP, Kizer JR, Shah SJ, Psaty BM, Bartz TM, Santhanakrishnan R, Lee DS, Chan C, Liu K, Blaha MJ, Hillege HL, van der Harst P, van Gilst WH, Kop WJ, Gansevoort RT, Vasan RS, Gardin JM, Levy D, Gottdiener JS, de Boer RA, Larson MG. Predicting Heart Failure With Preserved and Reduced Ejection Fraction: The International Collaboration on Heart Failure Subtypes. Circ Heart Fail. 2016 06; 9(6). PMID: 27266854.
    Citations: 46     Fields:    Translation:Humans
  54. van der Velde AR, Meijers WC, Ho JE, Brouwers FP, Rienstra M, Bakker SJ, Muller Kobold AC, van Veldhuisen DJ, van Gilst WH, van der Harst P, de Boer RA. Serial galectin-3 and future cardiovascular disease in the general population. Heart. 2016 07 15; 102(14):1134-41. PMID: 27084804.
    Citations: 21     Fields:    Translation:HumansCells
  55. Santhanakrishnan R, Wang N, Larson MG, Magnani JW, Vasan RS, Wang TJ, Yap J, Feng L, Yap KB, Ong HY, Ng TP, Richards AM, Lam CS, Ho JE. Racial Differences in Electrocardiographic Characteristics and Prognostic Significance in Whites Versus Asians. J Am Heart Assoc. 2016 03 25; 5(3):e002956. PMID: 27016575.
    Citations: 5     Fields:    Translation:Humans
  56. Ho JE, Larson MG, Ghorbani A, Cheng S, Chen MH, Keyes M, Rhee EP, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes. PLoS One. 2016; 11(2):e0148361. PMID: 26863521.
    Citations: 52     Fields:    Translation:Humans
  57. Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction. Circulation. 2016 Feb 02; 133(5):484-92. PMID: 26746177.
    Citations: 90     Fields:    Translation:Humans
  58. Nayor M, Wang N, Larson MG, Vasan RS, Levy D, Ho JE. Circulating Galectin-3 Is Associated With Cardiometabolic Disease in the Community. J Am Heart Assoc. 2015 Dec 31; 5(1). PMID: 26722123.
    Citations: 4     Fields:    Translation:HumansCells
  59. AbouEzzeddine OF, Lala A, Khazanie PP, Shah R, Ho JE, Chen HH, Pang PS, McNulty SE, Anstrom KJ, Hernandez AF, Redfield MM. Evaluation of a provocative dyspnea severity score in acute heart failure. Am Heart J. 2016 Feb; 172:34-41. PMID: 26856213.
    Citations: 4     Fields:    Translation:Humans
  60. Wang YC, Liang CS, Gopal DM, Ayalon N, Donohue C, Santhanakrishnan R, Sandhu H, Perez AJ, Downing J, Gokce N, Colucci WS, Ho JE. Preclinical Systolic and Diastolic Dysfunctions in Metabolically Healthy and Unhealthy Obese Individuals. Circ Heart Fail. 2015 Sep; 8(5):897-904. PMID: 26175540.
    Citations: 18     Fields:    Translation:Humans
  61. Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Erratum: Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015 May 21; 6:7317. PMID: 25993905.
    Citations:    Fields:    
  62. Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015 Apr 13; 6:6791. PMID: 25864806.
    Citations: 39     Fields:    Translation:Humans
  63. Gopal DM, Santhanakrishnan R, Wang YC, Ayalon N, Donohue C, Rahban Y, Perez AJ, Downing J, Liang CS, Gokce N, Colucci WS, Ho JE. Impaired right ventricular hemodynamics indicate preclinical pulmonary hypertension in patients with metabolic syndrome. J Am Heart Assoc. 2015 Mar 10; 4(3):e001597. PMID: 25758604.
    Citations: 19     Fields:    Translation:Humans
  64. Ho JE, Sritara P, deFilippi CR, Wang TJ. Soluble ST2 testing in the general population. Am J Cardiol. 2015 Apr 02; 115(7 Suppl):22B-5B. PMID: 25665763.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  65. Ho JE, Magnani JW. The MESA heart failure risk score: can't we do more? Heart. 2015 Jan; 101(1):7-9. PMID: 25387949.
    Citations:    Fields:    Translation:Humans
  66. Gopal DM, Larson MG, Januzzi JL, Cheng S, Ghorbani A, Wollert KC, Kempf T, D'Agostino RB, Polak JF, Ramachandran VS, Wang TJ, Ho JE. Biomarkers of cardiovascular stress and subclinical atherosclerosis in the community. Clin Chem. 2014 Nov; 60(11):1402-8. PMID: 25237063.
    Citations: 6     Fields:    Translation:Humans
  67. Ho JE, Arora P, Walford GA, Ghorbani A, Guanaga DP, Dhakal BP, Nathan DI, Buys ES, Florez JC, Newton-Cheh C, Lewis GD, Wang TJ. Effect of phosphodiesterase inhibition on insulin resistance in obese individuals. J Am Heart Assoc. 2014 Sep 11; 3(5):e001001. PMID: 25213566.
    Citations: 14     Fields:    Translation:HumansCells
  68. Subramanian S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG, Cheng S, Wang TJ, Mehta NN, Levy D. Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2100-5. PMID: 25060794.
    Citations: 22     Fields:    Translation:Humans
  69. Ayalon N, Gopal DM, Mooney DM, Simonetti JS, Grossman JR, Dwivedi A, Donohue C, Perez AJ, Downing J, Gokce N, Miller EJ, Liang CS, Apovian CM, Colucci WS, Ho JE. Preclinical left ventricular diastolic dysfunction in metabolic syndrome. Am J Cardiol. 2014 Sep 15; 114(6):838-42. PMID: 25084691.
    Citations: 17     Fields:    Translation:Humans
  70. Ho JE, Larson MG, Ghorbani A, Cheng S, Coglianese EE, Vasan RS, Wang TJ. Long-term cardiovascular risks associated with an elevated heart rate: the Framingham Heart Study. J Am Heart Assoc. 2014 May 08; 3(3):e000668. PMID: 24811610.
    Citations: 33     Fields:    Translation:Humans
  71. Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ. Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur Heart J. 2014 Nov 07; 35(42):2972-9. PMID: 24742886.
    Citations: 45     Fields:    Translation:HumansCells
  72. Ho JE, Yin X, Levy D, Vasan RS, Magnani JW, Ellinor PT, McManus DD, Lubitz SA, Larson MG, Benjamin EJ. Galectin 3 and incident atrial fibrillation in the community. Am Heart J. 2014 May; 167(5):729-34.e1. PMID: 24766984.
    Citations: 32     Fields:    Translation:Humans
  73. Rienstra M, Yin X, Larson MG, Fontes JD, Magnani JW, McManus DD, McCabe EL, Coglianese EE, Amponsah M, Ho JE, Januzzi JL, Wollert KC, Fradley MG, Vasan RS, Ellinor PT, Wang TJ, Benjamin EJ. Relation between soluble ST2, growth differentiation factor-15, and high-sensitivity troponin I and incident atrial fibrillation. Am Heart J. 2014 Jan; 167(1):109-115.e2. PMID: 24332149.
    Citations: 18     Fields:    Translation:Humans
  74. Wang TJ, Ngo D, Psychogios N, Dejam A, Larson MG, Vasan RS, Ghorbani A, O'Sullivan J, Cheng S, Rhee EP, Sinha S, McCabe E, Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M, Pierce KA, Souza AL, Yu Y, Carter C, Light PE, Melander O, Clish CB, Gerszten RE. 2-Aminoadipic acid is a biomarker for diabetes risk. J Clin Invest. 2013 Oct; 123(10):4309-17. PMID: 24091325.
    Citations: 122     Fields:    Translation:HumansAnimalsCells
  75. Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ, Dehghan A, Lu C, Levy D, Newton-Cheh C, Lin H, Felix JF, Schreiter ER, Vasan RS, Januzzi JL, Lee RT, Wang TJ. Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J Clin Invest. 2013 Oct; 123(10):4208-18. PMID: 23999434.
    Citations: 31     Fields:    Translation:HumansCells
  76. Ho JE, Hwang SJ, Wollert KC, Larson MG, Cheng S, Kempf T, Vasan RS, Januzzi JL, Wang TJ, Fox CS. Biomarkers of cardiovascular stress and incident chronic kidney disease. Clin Chem. 2013 Nov; 59(11):1613-20. PMID: 23873716.
    Citations: 33     Fields:    Translation:Humans
  77. Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, Vasan RS, Florez JC, Clish C, Yeh JR, Wang TJ, Gerszten RE. A genome-wide association study of the human metabolome in a community-based cohort. Cell Metab. 2013 Jul 02; 18(1):130-43. PMID: 23823483.
    Citations: 94     Fields:    Translation:Humans
  78. Ho JE, Larson MG, Ghorbani A, Cheng S, Vasan RS, Wang TJ, Januzzi JL. Soluble ST2 predicts elevated SBP in the community. J Hypertens. 2013 Jul; 31(7):1431-6; discussion 1436. PMID: 23615326.
    Citations: 12     Fields:    Translation:Humans
  79. O'Seaghdha CM, Hwang SJ, Ho JE, Vasan RS, Levy D, Fox CS. Elevated galectin-3 precedes the development of CKD. J Am Soc Nephrol. 2013 Sep; 24(9):1470-7. PMID: 23766533.
    Citations: 41     Fields:    Translation:Humans
  80. Kraigher-Krainer E, Lyass A, Massaro JM, Lee DS, Ho JE, Levy D, Kannel WB, Vasan RS. Association of physical activity and heart failure with preserved vs. reduced ejection fraction in the elderly: the Framingham Heart Study. Eur J Heart Fail. 2013 Jul; 15(7):742-6. PMID: 23435761.
    Citations: 28     Fields:    Translation:Humans
  81. Austin PC, Tu JV, Ho JE, Levy D, Lee DS. Using methods from the data-mining and machine-learning literature for disease classification and prediction: a case study examining classification of heart failure subtypes. J Clin Epidemiol. 2013 Apr; 66(4):398-407. PMID: 23384592.
    Citations: 49     Fields:    Translation:Humans
  82. Ho JE, Larson MG, Vasan RS, Ghorbani A, Cheng S, Rhee EP, Florez JC, Clish CB, Gerszten RE, Wang TJ. Metabolite profiles during oral glucose challenge. Diabetes. 2013 Aug; 62(8):2689-98. PMID: 23382451.
    Citations: 51     Fields:    Translation:Humans
  83. Ho JE, Lyass A, Lee DS, Vasan RS, Kannel WB, Larson MG, Levy D. Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction. Circ Heart Fail. 2013 Mar; 6(2):279-86. PMID: 23271790.
    Citations: 79     Fields:    Translation:Humans
  84. Waters DD, Ho JE, Boekholdt SM, DeMicco DA, Kastelein JJ, Messig M, Breazna A, Pedersen TR. Cardiovascular event reduction versus new-onset diabetes during atorvastatin therapy: effect of baseline risk factors for diabetes. J Am Coll Cardiol. 2013 Jan 15; 61(2):148-52. PMID: 23219296.
    Citations: 39     Fields:    Translation:Humans
  85. Coglianese EE, Larson MG, Vasan RS, Ho JE, Ghorbani A, McCabe EL, Cheng S, Fradley MG, Kretschman D, Gao W, O'Connor G, Wang TJ, Januzzi JL. Distribution and clinical correlates of the interleukin receptor family member soluble ST2 in the Framingham Heart Study. Clin Chem. 2012 Dec; 58(12):1673-81. PMID: 23065477.
    Citations: 51     Fields:    Translation:Humans
  86. Ho JE, Mahajan A, Chen MH, Larson MG, McCabe EL, Ghorbani A, Cheng S, Johnson AD, Lindgren CM, Kempf T, Lind L, Ingelsson E, Vasan RS, Januzzi J, Wollert KC, Morris AP, Wang TJ. Clinical and genetic correlates of growth differentiation factor 15 in the community. Clin Chem. 2012 Nov; 58(11):1582-91. PMID: 22997280.
    Citations: 30     Fields:    Translation:Humans
  87. Ho JE, Liu C, Lyass A, Courchesne P, Pencina MJ, Vasan RS, Larson MG, Levy D. Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community. J Am Coll Cardiol. 2012 Oct 02; 60(14):1249-56. PMID: 22939561.
    Citations: 153     Fields:    Translation:Humans
  88. Wang TJ, Wollert KC, Larson MG, Coglianese E, McCabe EL, Cheng S, Ho JE, Fradley MG, Ghorbani A, Xanthakis V, Kempf T, Benjamin EJ, Levy D, Vasan RS, Januzzi JL. Prognostic utility of novel biomarkers of cardiovascular stress: the Framingham Heart Study. Circulation. 2012 Sep 25; 126(13):1596-604. PMID: 22907935.
    Citations: 132     Fields:    Translation:Humans
  89. Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, Ganz P, Deeks SG, Hsue PY. The association of CD4+ T-cell counts and cardiovascular risk in treated HIV disease. AIDS. 2012 Jun 01; 26(9):1115-20. PMID: 22382147.
    Citations: 34     Fields:    Translation:HumansCells
  90. Ho JE, Gona P, Pencina MJ, Tu JV, Austin PC, Vasan RS, Kannel WB, D'Agostino RB, Lee DS, Levy D. Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community. Eur Heart J. 2012 Jul; 33(14):1734-41. PMID: 22507977.
    Citations: 36     Fields:    Translation:Humans
  91. Ho JE, Waters DD, Kean A, Wilson DJ, Demicco DA, Breazna A, Wun CC, Deedwania PC, Khush KK. Relation of improvement in estimated glomerular filtration rate with atorvastatin to reductions in hospitalizations for heart failure (from the Treating to New Targets [TNT] study). Am J Cardiol. 2012 Jun 15; 109(12):1761-6. PMID: 22459310.
    Citations: 3     Fields:    Translation:Humans
  92. Hsue PY, Ordovas K, Lee T, Reddy G, Gotway M, Schnell A, Ho JE, Selby V, Madden E, Martin JN, Deeks SG, Ganz P, Waters DD. Carotid intima-media thickness among human immunodeficiency virus-infected patients without coronary calcium. Am J Cardiol. 2012 Mar 01; 109(5):742-7. PMID: 22169125.
    Citations: 27     Fields:    Translation:Humans
  93. Secemsky EA, Lange D, Ho JE, Brayton K, Ganz PA, Farr G, Macgregor JS, Hsue PY. Improvement in revascularization time after creation of a coronary catheterization laboratory at a public hospital. Arch Intern Med. 2012 Jan 23; 172(2):193-4. PMID: 22123753.
    Citations:    Fields:    Translation:Humans
  94. Ho JE, Wang TJ. Growth differentiation factor 15: a canary in a coal mine? Clin Chem. 2012 Jan; 58(1):3-5. PMID: 22065154.
    Citations: 3     Fields:    Translation:Humans
  95. Preiss D, Seshasai SR, Welsh P, Murphy SA, Ho JE, Waters DD, DeMicco DA, Barter P, Cannon CP, Sabatine MS, Braunwald E, Kastelein JJ, de Lemos JA, Blazing MA, Pedersen TR, Tikkanen MJ, Sattar N, Ray KK. Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis. JAMA. 2011 Jun 22; 305(24):2556-64. PMID: 21693744.
    Citations: 334     Fields:    Translation:Humans
  96. Lam CS, Lyass A, Kraigher-Krainer E, Massaro JM, Lee DS, Ho JE, Levy D, Redfield MM, Pieske BM, Benjamin EJ, Vasan RS. Cardiac dysfunction and noncardiac dysfunction as precursors of heart failure with reduced and preserved ejection fraction in the community. Circulation. 2011 Jul 05; 124(1):24-30. PMID: 21670229.
    Citations: 84     Fields:    Translation:Humans
  97. Waters DD, Ho JE, DeMicco DA, Breazna A, Arsenault BJ, Wun CC, Kastelein JJ, Colhoun H, Barter P. Predictors of new-onset diabetes in patients treated with atorvastatin: results from 3 large randomized clinical trials. J Am Coll Cardiol. 2011 Apr 05; 57(14):1535-45. PMID: 21453832.
    Citations: 88     Fields:    Translation:Humans
  98. Ho JE, Levy D, Rose L, Johnson AD, Ridker PM, Chasman DI. Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study. J Hypertens. 2011 Jan; 29(1):62-9. PMID: 21045733.
    Citations: 29     Fields:    Translation:Humans
  99. Ho JE, Deeks SG, Hecht FM, Xie Y, Schnell A, Martin JN, Ganz P, Hsue PY. Initiation of antiretroviral therapy at higher nadir CD4+ T-cell counts is associated with reduced arterial stiffness in HIV-infected individuals. AIDS. 2010 Jul 31; 24(12):1897-905. PMID: 20543654.
    Citations: 32     Fields:    Translation:HumansCells
  100. Ho JE, Levy D. B-type natriuretic peptide testing in the general population: are we ready for prime time? J Am Coll Cardiol. 2010 May 11; 55(19):2148-9. PMID: 20447540.
    Citations:    Fields:    Translation:Humans
  101. Ho JE, Bittner V, Demicco DA, Breazna A, Deedwania PC, Waters DD. Usefulness of heart rate at rest as a predictor of mortality, hospitalization for heart failure, myocardial infarction, and stroke in patients with stable coronary heart disease (Data from the Treating to New Targets [TNT] trial). Am J Cardiol. 2010 Apr 01; 105(7):905-11. PMID: 20346304.
    Citations: 18     Fields:    Translation:Humans
  102. Hsue PY, Hunt PW, Ho JE, Farah HH, Schnell A, Hoh R, Martin JN, Deeks SG, Bolger AF. Impact of HIV infection on diastolic function and left ventricular mass. Circ Heart Fail. 2010 Jan; 3(1):132-9. PMID: 19933410.
    Citations: 61     Fields:    Translation:Humans
  103. Hsue PY, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P, Deeks SG. Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. AIDS. 2009 Sep 24; 23(15):2021-7. PMID: 19542863.
    Citations: 51     Fields:    Translation:HumansCells
  104. Ho JE, Hsue PY. Cardiovascular manifestations of HIV infection. Heart. 2009 Jul; 95(14):1193-202. PMID: 19564432.
    Citations: 37     Fields:    Translation:Humans
  105. Ganz P, Ho JE, Hsue PY. Structural and functional manifestations of human atherosclerosis: do they run in parallel? Eur Heart J. 2009 Jul; 30(13):1556-8. PMID: 19502231.
    Citations:    Fields:    Translation:Humans
  106. Nguyen VT, Ho JE, Ho CY, Givertz MM, Stevenson LW. Handheld echocardiography offers rapid assessment of clinical volume status. Am Heart J. 2008 Sep; 156(3):537-42. PMID: 18760138.
    Citations: 7     Fields:    Translation:Humans
  107. Ho JE, Teerlink JR. Role of tolvaptan in acute decompensated heart failure. Expert Rev Cardiovasc Ther. 2008 Jun; 6(5):601-8. PMID: 18510477.
    Citations: 2     Fields:    Translation:Humans
  108. Ho JE, Paultre F, Mosca L. The gender gap in coronary heart disease mortality: is there a difference between blacks and whites? J Womens Health (Larchmt). 2005 Mar; 14(2):117-27. PMID: 15775729.
    Citations: 14     Fields:    Translation:Humans
  109. Ho JE, Paultre F, Mosca L. Is diabetes mellitus a cardiovascular disease risk equivalent for fatal stroke in women? Data from the Women's Pooling Project. Stroke. 2003 Dec; 34(12):2812-6. PMID: 14657546.
    Citations: 21     Fields:    Translation:Humans
  110. Ho JE, Paultre F, Mosca L. Lifestyle changes in New Yorkers after September 11, 2001 (data from the Post-Disaster Heart Attack Prevention Program). Am J Cardiol. 2002 Sep 15; 90(6):680-2. PMID: 12231109.
    Citations: 7     Fields:    Translation:Humans
  111. Ho JE, Mosca L. Postmenopausal hormone replacement therapy and atherosclerosis. Curr Atheroscler Rep. 2002 Sep; 4(5):387-95. PMID: 12162939.
    Citations: 5     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.