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Michael Avery Welsh, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F32GM123579 (WELSH, MICHAEL AVERY) May 1, 2017 - Apr 30, 2020
    NIH
    Biochemical characterization of LMW PBPS with novel transpeptidase activity
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Palace SG, Wang Y, Rubin DH, Welsh MA, Mortimer TD, Cole K, Eyre DW, Walker S, Grad YH. RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates. Elife. 2020 02 03; 9. PMID: 32011233.
    Citations: 11     Fields:    Translation:Cells
  2. Yang Y, Yang HH, Tang B, Wu AML, Flanders KC, Moshkovich N, Weinberg DS, Welsh MA, Weng J, Ochoa HJ, Hu TY, Herrmann MA, Chen J, Edmondson EF, Simpson RM, Liu F, Liu H, Lee MP, Wakefield LM. The Outcome of TGFß Antagonism in Metastatic Breast Cancer Models In Vivo Reflects a Complex Balance between Tumor-Suppressive and Proprogression Activities of TGFß. Clin Cancer Res. 2020 02 01; 26(3):643-656. PMID: 31582516; PMCID: PMC8182485.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  3. Welsh MA, Schaefer K, Taguchi A, Kahne D, Walker S. Direction of Chain Growth and Substrate Preferences of Shape, Elongation, Division, and Sporulation-Family Peptidoglycan Glycosyltransferases. J Am Chem Soc. 2019 08 21; 141(33):12994-12997. PMID: 31386359; PMCID: PMC6738341.
    Citations: 8     Fields:    Translation:HumansCells
  4. Taguchi A, Welsh MA, Marmont LS, Lee W, Sjodt M, Kruse AC, Kahne D, Bernhardt TG, Walker S. FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein. Nat Microbiol. 2019 04; 4(4):587-594. PMID: 30692671; PMCID: PMC6430707.
    Citations: 101     Fields:    Translation:Cells
  5. Buss JA, Baidin V, Welsh MA, Flores-Kim J, Cho H, Wood BM, Uehara T, Walker S, Kahne D, Bernhardt TG. Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery. Antimicrob Agents Chemother. 2019 01; 63(1). PMID: 30323039; PMCID: PMC6325226.
    Citations: 8     Fields:    Translation:Cells
  6. Baranowski C, Welsh MA, Sham LT, Eskandarian HA, Lim HC, Kieser KJ, Wagner JC, McKinney JD, Fantner GE, Ioerger TR, Walker S, Bernhardt TG, Rubin EJ, Rego EH. Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape. Elife. 2018 10 16; 7. PMID: 30324906; PMCID: PMC6231781.
    Citations: 42     Fields:    Translation:Cells
  7. Welsh MA, Taguchi A, Schaefer K, Van Tyne D, Lebreton F, Gilmore MS, Kahne D, Walker S. Identification of a Functionally Unique Family of Penicillin-Binding Proteins. J Am Chem Soc. 2017 12 13; 139(49):17727-17730. PMID: 29182854; PMCID: PMC5729098.
    Citations: 25     Fields:    Translation:Cells
  8. Gustafsson K, Welsh M. Maintenance of hematopoietic stem cell dormancy: yet another role for the macrophage. Stem Cell Investig. 2016; 3:46. PMID: 27777935; PMCID: PMC5067365.
    Citations:    
  9. Kratochvil MJ, Welsh MA, Manna U, Ortiz BJ, Blackwell HE, Lynn DM. Slippery Liquid-Infused Porous Surfaces that Prevent Bacterial Surface Fouling and Inhibit Virulence Phenotypes in Surrounding Planktonic Cells. ACS Infect Dis. 2016 07 08; 2(7):509-17. PMID: 27626103; PMCID: PMC5198836.
    Citations: 10     Fields:    Translation:CellsPHPublic Health
  10. Welsh MA, Blackwell HE. Chemical probes of quorum sensing: from compound development to biological discovery. FEMS Microbiol Rev. 2016 09; 40(5):774-94. PMID: 27268906; PMCID: PMC5007280.
    Citations: 52     Fields:    Translation:Cells
  11. Manna U, Raman N, Welsh MA, Zayas-Gonzalez YM, Blackwell HE, Palecek SP, Lynn DM. Slippery Liquid-Infused Porous Surfaces that Prevent Microbial Surface Fouling and Kill Non-Adherent Pathogens in Surrounding Media: A Controlled Release Approach. Adv Funct Mater. 2016 Jun 07; 26(21):3599-3611. PMID: 28713229; PMCID: PMC5507623.
    Citations: 13     
  12. Welsh MA, Blackwell HE. Chemical Genetics Reveals Environment-Specific Roles for Quorum Sensing Circuits in Pseudomonas aeruginosa. Cell Chem Biol. 2016 Mar 17; 23(3):361-9. PMID: 26905657.
    Citations: 39     Fields:    Translation:Cells
  13. Moore JD, Rossi FM, Welsh MA, Nyffeler KE, Blackwell HE. A Comparative Analysis of Synthetic Quorum Sensing Modulators in Pseudomonas aeruginosa: New Insights into Mechanism, Active Efflux Susceptibility, Phenotypic Response, and Next-Generation Ligand Design. J Am Chem Soc. 2015 Nov 25; 137(46):14626-39. PMID: 26491787; PMCID: PMC4665086.
    Citations: 37     Fields:    Translation:Cells
  14. Welsh MA, Eibergen NR, Moore JD, Blackwell HE. Small molecule disruption of quorum sensing cross-regulation in pseudomonas aeruginosa causes major and unexpected alterations to virulence phenotypes. J Am Chem Soc. 2015 Feb 04; 137(4):1510-9. PMID: 25574853; PMCID: PMC4372995.
    Citations: 51     Fields:    Translation:HumansCells
  15. Sato M, Kadota M, Tang B, Yang HH, Yang YA, Shan M, Weng J, Welsh MA, Flanders KC, Nagano Y, Michalowski AM, Clifford RJ, Lee MP, Wakefield LM. An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-ß in human breast cancer. Breast Cancer Res. 2014 Jun 02; 16(3):R57. PMID: 24890385.
    Citations: 12     Fields:    Translation:HumansCells
  16. Stacy DM, Welsh MA, Rather PN, Blackwell HE. Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-Acyl homoserine lactones. ACS Chem Biol. 2012 Oct 19; 7(10):1719-28. PMID: 22853441.
    Citations: 49     Fields:    Translation:Cells
  17. Kohn EA, Du Z, Sato M, Van Schyndle CM, Welsh MA, Yang YA, Stuelten CH, Tang B, Ju W, Bottinger EP, Wakefield LM. A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFß signaling in the mammary gland. Breast Cancer Res. 2010; 12(5):R83. PMID: 20942910.
    Citations: 16     Fields:    Translation:AnimalsCells
  18. Annerén C, Lindholm CK, Kriz V, Welsh M. The FRK/RAK-SHB signaling cascade: a versatile signal-transduction pathway that regulates cell survival, differentiation and proliferation. Curr Mol Med. 2003 Jun; 3(4):313-24. PMID: 12776987.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.