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Walter Fontana, PH.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AG034994 (FONTANA, WALTER) Feb 1, 2010 - Jan 31, 2015
    NIH/NIA
    The variability of the lifespan phenotype in C.elegans
    Role: Principal Investigator
  2. R03AG032481 (FONTANA, WALTER) Sep 1, 2008 - Aug 31, 2010
    NIH/NIA
    Automated Acquisition of C. elegans Survival Curves with a Flatbed Scanner
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Boutillier P, Maasha M, Li X, Medina-Abarca HF, Krivine J, Feret J, Cristescu I, Forbes AG, Fontana W. The Kappa platform for rule-based modeling. Bioinformatics. 2018 Jul 01; 34(13):i583-i592. PMID: 29950016.
    View in: PubMed
  2. Apfeld J, Fontana W. Age-Dependence and Aging-Dependence: Neuronal Loss and Lifespan in a C. elegans Model of Parkinson's Disease. Biology (Basel). 2017 Dec 23; 7(1). PMID: 29295479.
    View in: PubMed
  3. Forbes AG, Burks A, Lee K, Li X, Boutillier P, Krivine J, Fontana W. Dynamic Influence Networks for Rule-Based Models. IEEE Trans Vis Comput Graph. 2018 Jan; 24(1):184-194. PMID: 28866584.
    View in: PubMed
  4. Stroustrup N, Anthony WE, Nash ZM, Gowda V, Gomez A, López-Moyado IF, Apfeld J, Fontana W. The temporal scaling of Caenorhabditis elegans ageing. Nature. 2016 Feb 04; 530(7588):103-7. PMID: 26814965; PMCID: PMC4828198.
  5. Romero-Aristizabal C, Marks DS, Fontana W, Apfeld J. Regulated spatial organization and sensitivity of cytosolic protein oxidation in Caenorhabditis elegans. Nat Commun. 2014 Sep 29; 5:5020. PMID: 25262602; PMCID: PMC4181376.
  6. Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q. An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology. PLoS Genet. 2014 Mar; 10(3):e1004225. PMID: 24675767; PMCID: PMC3967928.
  7. Stroustrup N, Ulmschneider BE, Nash ZM, López-Moyado IF, Apfeld J, Fontana W. The Caenorhabditis elegans Lifespan Machine. Nat Methods. 2013 Jul; 10(7):665-70. PMID: 23666410; PMCID: PMC3865717.
  8. Rowland MA, Fontana W, Deeds EJ. Crosstalk and competition in signaling networks. Biophys J. 2012 Dec 05; 103(11):2389-98. PMID: 23283238; PMCID: PMC3514525.
  9. Deeds EJ, Krivine J, Feret J, Danos V, Fontana W. Combinatorial complexity and compositional drift in protein interaction networks. PLoS One. 2012; 7(3):e32032. PMID: 22412851.
    View in: PubMed
  10. Deeds EJ, Bachman JA, Fontana W. Optimizing ring assembly reveals the strength of weak interactions. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2348-53. PMID: 22308356; PMCID: PMC3289332.
  11. Deeds EJ, Savage V, Fontana W. Curvature in metabolic scaling: a reply to MacKay. J Theor Biol. 2011 Jul 07; 280(1):197-8. PMID: 21497609.
    View in: PubMed
  12. Harmer R, Danos V, Feret J, Krivine J, Fontana W. Intrinsic information carriers in combinatorial dynamical systems. Chaos. 2010 Sep; 20(3):037108. PMID: 20887074.
    View in: PubMed
  13. Kolokotrones T, Deeds EJ, Fontana W. Curvature in metabolic scaling. Nature. 2010 Apr 01; 464(7289):753-6. PMID: 20360740.
    View in: PubMed
  14. Hulme SE, Shevkoplyas SS, McGuigan AP, Apfeld J, Fontana W, Whitesides GM. Lifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegans. Lab Chip. 2010 Mar 07; 10(5):589-97. PMID: 20162234; PMCID: PMC3060707.
  15. Feret J, Danos V, Krivine J, Harmer R, Fontana W. Internal coarse-graining of molecular systems. Proc Natl Acad Sci U S A. 2009 Apr 21; 106(16):6453-8. PMID: 19346467; PMCID: PMC2672529.
  16. Savage VM, Deeds EJ, Fontana W. Sizing up allometric scaling theory. PLoS Comput Biol. 2008 Sep 12; 4(9):e1000171. PMID: 18787686; PMCID: PMC2518954.
  17. Hulme SE, Shevkoplyas SS, Apfeld J, Fontana W, Whitesides GM. A microfabricated array of clamps for immobilizing and imaging C. elegans. Lab Chip. 2007 Nov; 7(11):1515-23. PMID: 17960280.
    View in: PubMed
  18. Fontana W. Chemistry. Pulling strings. Science. 2006 Dec 08; 314(5805):1552-3. PMID: 17158311.
    View in: PubMed
  19. de Visser JA, Hermisson J, Wagner GP, Ancel Meyers L, Bagheri-Chaichian H, Blanchard JL, Chao L, Cheverud JM, Elena SF, Fontana W, Gibson G, Hansen TF, Krakauer D, Lewontin RC, Ofria C, Rice SH, von Dassow G, Wagner A, Whitlock MC. Perspective: Evolution and detection of genetic robustness. Evolution. 2003 Sep; 57(9):1959-72. PMID: 14575319.
    View in: PubMed
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.