Harvard Catalyst Profiles

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David Samuel Uygun, Ph.D.

Title
Institution
Department
Address

Biography
Imperial College London, United KingdomPHD01/2016Neuroscience
Imperial College London, United KingdomMRes11/2012Experimental Physiology and Drug Discovery
University of Newcastle upon Tyne, United KingdomBSc06/2010Psychology
2019
Travel Grant
2018
Travel Grant
2017 - 2018
T32 Postdoctoral Training Grant in Sleep, Circadian and Respiratory Neurobiology
2015
Travel Award
2015
DoLS Travel Award

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. IK2BX00490 (Uygun) Jan 1, 2020 - Dec 31, 2024
    Veterans Affairs

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. McNally JM, Aguilar DD, Katsuki F, Radzik LK, Schiffino FL, Uygun DS, McKenna JT, Strecker RE, Deisseroth K, Spencer KM, Brown RE. Optogenetic manipulation of an ascending arousal system tunes cortical broadband gamma power and reveals functional deficits relevant to schizophrenia. Mol Psychiatry. 2020 Jul 20. PMID: 32690865.
    Citations:    
  2. McKenna JT, Thankachan S, Uygun DS, Shukla C, McNally JM, Schiffino FL, Cordeira J, Katsuki F, Zant JC, Gamble MC, Deisseroth K, McCarley RW, Brown RE, Strecker RE, Basheer R. Basal Forebrain Parvalbumin Neurons Mediate Arousals from Sleep Induced by Hypercarbia or Auditory Stimuli. Curr Biol. 2020 Jun 22; 30(12):2379-2385.e4. PMID: 32413301.
    Citations:    
  3. Ghoshal A, Uygun DS, Yang L, McNally JM, Lopez-Huerta VG, Arias-Garcia MA, Baez-Nieto D, Allen A, Fitzgerald M, Choi S, Zhang Q, Hope JM, Yan K, Mao X, Nicholson TB, Imaizumi K, Fu Z, Feng G, Brown RE, Strecker RE, Purcell SM, Pan JQ. Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits. Transl Psychiatry. 2020 Jan 23; 10(1):29. PMID: 32066662.
    Citations:    
  4. Thankachan S, Katsuki F, McKenna JT, Yang C, Shukla C, Deisseroth K, Uygun DS, Strecker RE, Brown RE, McNally JM, Basheer R. Thalamic Reticular Nucleus Parvalbumin Neurons Regulate Sleep Spindles and Electrophysiological Aspects of Schizophrenia in Mice. Sci Rep. 2019 03 05; 9(1):3607. PMID: 30837664.
    Citations:    
  5. Uygun DS, Katsuki F, Bolortuya Y, Aguilar DD, McKenna JT, Thankachan S, McCarley RW, Basheer R, Brown RE, Strecker RE, McNally JM. Validation of an automated sleep spindle detection method for mouse electroencephalography. Sleep. 2019 02 01; 42(2). PMID: 30476300.
    Citations:    Fields:    
  6. Uygun DS, Ye Z, Zecharia AY, Harding EC, Yu X, Yustos R, Vyssotski AL, Brickley SG, Franks NP, Wisden W. Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons. J Neurosci. 2016 11 02; 36(44):11171-11184. PMID: 27807161.
    Citations: 1     Fields:    Translation:AnimalsCells
  7. Yu X, Ye Z, Houston CM, Zecharia AY, Ma Y, Zhang Z, Uygun DS, Parker S, Vyssotski AL, Yustos R, Franks NP, Brickley SG, Wisden W. Wakefulness Is Governed by GABA and Histamine Cotransmission. Neuron. 2015 Jul 01; 87(1):164-78. PMID: 26094607.
    Citations: 18     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.