Harvard Catalyst Profiles

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Alexandre Lellouch, M.D.

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Biography
education and training
Grenoble Alpes University, FrancePhD03/2022Bioengineering
Université Paris Est Créteil (UPEC), FranceMD09/12Medicine
Université Paris Est Créteil (UPEC), FranceM.Sc09/2016Immunology

Overview

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. W81XWH2210957 (Lellouch) Sep 1, 2022 - Sep 1, 2025
    U.S. Army Medical Research Acquisition Activity
    Stable mixed chimerism and tolerance of vascularized composite allografts via Bcl-2 inhibition
    Role Description: The main objective of this research proposal is to establish the successful nontoxic regimen with Bcl-2 inhibition from Kawai group in kidney allograft to induce persistent mixed chimerism in MHC fully mismatched cynomolgus monkey BMT in VCA.
    Role: Partnering PI
  2. 1R01EB028782-01A1 (Parekkadan) Sep 1, 2021 - Sep 1, 2025
    National Institute of Biomedical Imaging and Bioengineering
    ADVANCE Genetic-engineered control of the immunogeneic state of vascular composite allografts during preservation
    Role Description: The objective of this program is to engineer a library of inflammation biosensor constructs into MSCs and sensitively track the viability and theranostic performance of these cells during clinically relevant VCA transplant settings in rat models. Our long-term goal is to use cell biosensors as a broad way to mitigate the rejection episodes.
    Role: co-investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.