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Assaf Alon, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gao Y, Barajas-Ornelas RDC, Amon JD, Ramírez-Guadiana FH, Alon A, Brock KP, Marks DS, Kruse AC, Rudner DZ. The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination. Genes Dev. 2022 05 01; 36(9-10):634-646. PMID: 35654455; PMCID: PMC9186386.
    Citations:    Fields:    Translation:Cells
  2. Alon A, Lyu J, Braz JM, Tummino TA, Craik V, O'Meara MJ, Webb CM, Radchenko DS, Moroz YS, Huang XP, Liu Y, Roth BL, Irwin JJ, Basbaum AI, Shoichet BK, Kruse AC. Structures of the s2 receptor enable docking for bioactive ligand discovery. Nature. 2021 Dec; 600(7890):759-764. PMID: 34880501; PMCID: PMC8867396.
    Citations: 8     Fields:    Translation:Animals
  3. Okalang U, Mualem Bar-Ner B, Rajan KS, Friedman N, Aryal S, Egarmina K, Hope R, Khazanov N, Senderowitz H, Alon A, Fass D, Michaeli S. The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3. mBio. 2021 12 21; 12(6):e0260221. PMID: 34844425; PMCID: PMC8630539.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Artzi L, Alon A, Brock KP, Green AG, Tam A, Ramírez-Guadiana FH, Marks D, Kruse A, Rudner DZ. Dormant spores sense amino acids through the B subunits of their germination receptors. Nat Commun. 2021 11 25; 12(1):6842. PMID: 34824238.
    Citations: 4     Fields:    Translation:Cells
  5. Tummino TA, Rezelj VV, Fischer B, Fischer A, O'Meara MJ, Monel B, Vallet T, White KM, Zhang Z, Alon A, Schadt H, O'Donnell HR, Lyu J, Rosales R, McGovern BL, Rathnasinghe R, Jangra S, Schotsaert M, Galarneau JR, Krogan NJ, Urban L, Shokat KM, Kruse AC, García-Sastre A, Schwartz O, Moretti F, Vignuzzi M, Pognan F, Shoichet BK. Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2. Science. 2021 07 30; 373(6554):541-547. PMID: 34326236; PMCID: PMC8501941.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  6. Tummino TA, Rezelj VV, Fischer B, Fischer A, O'Meara MJ, Monel B, Vallet T, Zhang Z, Alon A, O'Donnell HR, Lyu J, Schadt H, White KM, Krogan NJ, Urban L, Shokat KM, Kruse AC, García-Sastre A, Schwartz O, Moretti F, Vignuzzi M, Pognan F, Shoichet BK. Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2. bioRxiv. 2021 Mar 24. PMID: 33791693; PMCID: PMC8010720.
    Citations:    
  7. Malone RW, Tisdall P, Fremont-Smith P, Liu Y, Huang XP, White KM, Miorin L, Moreno E, Alon A, Delaforge E, Hennecker CD, Wang G, Pottel J, Blair RV, Roy CJ, Smith N, Hall JM, Tomera KM, Shapiro G, Mittermaier A, Kruse AC, García-Sastre A, Roth BL, Glasspool-Malone J, Ricke DO. COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms. Front Pharmacol. 2021; 12:633680. PMID: 33833683.
    Citations: 26     
  8. Malone RW, Tisdall P, Fremont-Smith P, Liu Y, Huang XP, White KM, Miorin L, Olmo EMD, Alon A, Delaforge E, Hennecker CD, Wang G, Pottel J, Smith N, Hall JM, Shapiro G, Mittermaier A, Kruse AC, García-Sastre A, Roth BL, Glasspool-Malone J, Ricke DO. COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms. Res Sq. 2020 Jun 22. PMID: 32702719.
    Citations:    
  9. Javitt G, Grossman-Haham I, Alon A, Resnick E, Mutsafi Y, Ilani T, Fass D. cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures. Protein Sci. 2019 01; 28(1):228-238. PMID: 30367560; PMCID: PMC6295897.
    Citations: 3     Fields:    Translation:HumansCells
  10. Alon A, Schmidt HR, Wood MD, Sahn JJ, Martin SF, Kruse AC. Identification of the gene that codes for the s2 receptor. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):7160-7165. PMID: 28559337; PMCID: PMC5502638.
    Citations: 97     Fields:    Translation:HumansAnimalsCells
  11. Alon A, Schmidt H, Zheng S, Kruse AC. Structural Perspectives on Sigma-1 Receptor Function. Adv Exp Med Biol. 2017; 964:5-13. PMID: 28315261.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  12. Lapidoth GD, Baran D, Pszolla GM, Norn C, Alon A, Tyka MD, Fleishman SJ. AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences. Proteins. 2015 Aug; 83(8):1385-406. PMID: 25670500; PMCID: PMC4881815.
    Citations: 35     Fields:    Translation:HumansCells
  13. Grossman I, Alon A, Ilani T, Fass D. An inhibitory antibody blocks the first step in the dithiol/disulfide relay mechanism of the enzyme QSOX1. J Mol Biol. 2013 Nov 15; 425(22):4366-78. PMID: 23867277.
    Citations: 12     Fields:    Translation:HumansCells
  14. Ilani T, Alon A, Grossman I, Horowitz B, Kartvelishvily E, Cohen SR, Fass D. A secreted disulfide catalyst controls extracellular matrix composition and function. Science. 2013 Jul 05; 341(6141):74-6. PMID: 23704371.
    Citations: 67     Fields:    Translation:HumansCells
  15. Hakim M, Ezerina D, Alon A, Vonshak O, Fass D. Exploring ORFan domains in giant viruses: structure of mimivirus sulfhydryl oxidase R596. PLoS One. 2012; 7(11):e50649. PMID: 23209798.
    Citations: 11     Fields:    Translation:Cells
  16. Limor-Waisberg K, Alon A, Mehlman T, Fass D. Phylogenetics and enzymology of plant quiescin sulfhydryl oxidase. FEBS Lett. 2012 Nov 30; 586(23):4119-25. PMID: 23068612.
    Citations: 2     Fields:    Translation:Cells
  17. Alon A, Grossman I, Gat Y, Kodali VK, DiMaio F, Mehlman T, Haran G, Baker D, Thorpe C, Fass D. The dynamic disulphide relay of quiescin sulphydryl oxidase. Nature. 2012 Aug 16; 488(7411):414-8. PMID: 22801504.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  18. DiMaio F, Terwilliger TC, Read RJ, Wlodawer A, Oberdorfer G, Wagner U, Valkov E, Alon A, Fass D, Axelrod HL, Das D, Vorobiev SM, Iwaï H, Pokkuluri PR, Baker D. Improved molecular replacement by density- and energy-guided protein structure optimization. Nature. 2011 May 26; 473(7348):540-3. PMID: 21532589; PMCID: PMC3365536.
    Citations: 128     Fields:    Translation:Cells
  19. Alon A, Heckler EJ, Thorpe C, Fass D. QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains. FEBS Lett. 2010 Apr 16; 584(8):1521-5. PMID: 20211621.
    Citations: 21     Fields:    Translation:HumansCells
  20. Heckler EJ, Alon A, Fass D, Thorpe C. Human quiescin-sulfhydryl oxidase, QSOX1: probing internal redox steps by mutagenesis. Biochemistry. 2008 Apr 29; 47(17):4955-63. PMID: 18393449.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.