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Samik Chakraborty, Ph.D.

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University of CalcuttaPh.D2015Biochemistry

1. Evaluating the role of c-Met pathway towards chemo-resistance and maintaining the
redox state of renal cancer cells.
2. Elucidating the involvement of c-Met pathway with oncogenic chemokines.
3. Delineating the contribution of c-Met pathway towards miRNAs involved in renal

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sabarwal A, Wedel J, Liu K, Zurakowski D, Chakraborty S, Flynn E, Briscoe DM, Balan M, Pal S. A Combination therapy using an mTOR inhibitor and Honokiol effectively induces autophagy through the modulation of AXL and Rubicon in renal cancer cells and restricts renal tumor growth following organ transplantation. Carcinogenesis. 2022 05 19; 43(4):360-370. PMID: 34965300; PMCID: PMC9118982.
    Citations:    Fields:    Translation:HumansAnimalsCells
  2. Chakraborty S, Balan M, Sabarwal A, Choueiri TK, Pal S. Metabolic reprogramming in renal cancer: Events of a metabolic disease. Biochim Biophys Acta Rev Cancer. 2021 08; 1876(1):188559. PMID: 33965513; PMCID: PMC8349779.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  3. Hamedani Y, Chakraborty S, Sabarwal A, Pal S, Bhowmick S, Balan M. Novel Honokiol-eluting PLGA-based scaffold effectively restricts the growth of renal cancer cells. PLoS One. 2020; 15(12):e0243837. PMID: 33332399; PMCID: PMC7746163.
    Citations: 2     Fields:    Translation:HumansCells
  4. Sabarwal A, Chakraborty S, Mahanta S, Banerjee S, Balan M, Pal S. A Novel Combination Treatment with Honokiol and Rapamycin Effectively Restricts c-Met-Induced Growth of Renal Cancer Cells, and also Inhibits the Expression of Tumor Cell PD-L1 Involved in Immune Escape. Cancers (Basel). 2020 Jul 03; 12(7). PMID: 32635337; PMCID: PMC7408055.
    Citations: 5     
  5. Chakraborty S, Balan M, Flynn E, Zurakowski D, Choueiri TK, Pal S. Activation of c-Met in cancer cells mediates growth-promoting signals against oxidative stress through Nrf2-HO-1. Oncogenesis. 2019 Jan 15; 8(2):7. PMID: 30647407; PMCID: PMC6333845.
    Citations: 14     
  6. Balan M, Chakraborty S, Pal S. Signaling Molecules in Posttransplantation Cancer. Clin Lab Med. 2019 03; 39(1):171-183. PMID: 30709505; PMCID: PMC6368395.
    Citations: 2     Fields:    Translation:HumansCells
  7. Balan M, Chakraborty S, Flynn E, Zurakowski D, Pal S. Honokiol inhibits c-Met-HO-1 tumor-promoting pathway and its cross-talk with calcineurin inhibitor-mediated renal cancer growth. Sci Rep. 2017 07 19; 7(1):5900. PMID: 28724911.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  8. Chakraborti S, Chakraborty S, Saha S, Manna A, Banerjee S, Adhikary A, Sarwar S, Hazra TK, Das T, Chakrabarti P. PEG-functionalized zinc oxide nanoparticles induce apoptosis in breast cancer cells through reactive oxygen species-dependent impairment of DNA damage repair enzyme NEIL2. Free Radic Biol Med. 2017 02; 103:35-47. PMID: 27940348.
    Citations: 6     Fields:    Translation:HumansCells
  9. Ray P, Guha D, Chakraborty J, Banerjee S, Adhikary A, Chakraborty S, Das T, Sa G. Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer. Sci Rep. 2016 09 13; 6:32979. PMID: 27622714; PMCID: PMC5020693.
    Citations: 19     Fields:    Translation:HumansCells
  10. Mukherjee S, Manna A, Bhattacharjee P, Mazumdar M, Saha S, Chakraborty S, Guha D, Adhikary A, Jana D, Gorain M, Mukherjee SA, Kundu GC, Sarkar DK, Das T. Non-migratory tumorigenic intrinsic cancer stem cells ensure breast cancer metastasis by generation of CXCR4(+) migrating cancer stem cells. Oncogene. 2016 09 15; 35(37):4937-48. PMID: 26923331.
    Citations: 21     Fields:    Translation:HumansCells
  11. Mukherjee S, Mazumdar M, Chakraborty S, Manna A, Saha S, Khan P, Bhattacharjee P, Guha D, Adhikary A, Mukhjerjee S, Das T. Curcumin inhibits breast cancer stem cell migration by amplifying the E-cadherin/ß-catenin negative feedback loop. Stem Cell Res Ther. 2014 Oct 14; 5(5):116. PMID: 25315241.
    Citations: 48     Fields:    Translation:HumansCells
  12. Chakraborty S, Das K, Saha S, Mazumdar M, Manna A, Chakraborty S, Mukherjee S, Khan P, Adhikary A, Mohanty S, Chattopadhyay S, Biswas SC, Sa G, Das T. Nuclear matrix protein SMAR1 represses c-Fos-mediated HPV18 E6 transcription through alteration of chromatin histone deacetylation. J Biol Chem. 2014 Oct 17; 289(42):29074-85. PMID: 25157104.
    Citations: 12     Fields:    Translation:HumansCells
  13. Adhikary A, Chakraborty S, Mazumdar M, Ghosh S, Mukherjee S, Manna A, Mohanty S, Nakka KK, Joshi S, De A, Chattopadhyay S, Sa G, Das T. Inhibition of epithelial to mesenchymal transition by E-cadherin up-regulation via repression of slug transcription and inhibition of E-cadherin degradation: dual role of scaffold/matrix attachment region-binding protein 1 (SMAR1) in breast cancer cells. J Biol Chem. 2014 Sep 12; 289(37):25431-44. PMID: 25086032.
    Citations: 38     Fields:    Translation:HumansCells
  14. Chakraborty S, Adhikary A, Mazumdar M, Mukherjee S, Bhattacharjee P, Guha D, Choudhuri T, Chattopadhyay S, Sa G, Sen A, Das T. Capsaicin-induced activation of p53-SMAR1 auto-regulatory loop down-regulates VEGF in non-small cell lung cancer to restrain angiogenesis. PLoS One. 2014; 9(6):e99743. PMID: 24926985.
    Citations: 25     Fields:    Translation:HumansCells
  15. Saha S, Bhattacharjee P, Mukherjee S, Mazumdar M, Chakraborty S, Khurana A, Nayak D, Manchanda R, Chakrabarty R, Das T, Sa G. Contribution of the ROS-p53 feedback loop in thuja-induced apoptosis of mammary epithelial carcinoma cells. Oncol Rep. 2014 Apr; 31(4):1589-98. PMID: 24482097.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  16. Mohanty S, Saha S, Md S Hossain D, Adhikary A, Mukherjee S, Manna A, Chakraborty S, Mazumdar M, Ray P, Das K, Chakraborty J, Sa G, Das T. ROS-PIAS? cross talk channelizes ATM signaling from resistance to apoptosis during chemosensitization of resistant tumors. Cell Death Dis. 2014 Jan 23; 5:e1021. PMID: 24457965.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  17. Chakraborty S, Mazumdar M, Mukherjee S, Bhattacharjee P, Adhikary A, Manna A, Chakraborty S, Khan P, Sen A, Das T. Restoration of p53/miR-34a regulatory axis decreases survival advantage and ensures Bax-dependent apoptosis of non-small cell lung carcinoma cells. FEBS Lett. 2014 Feb 14; 588(4):549-59. PMID: 24444609.
    Citations: 30     Fields:    Translation:HumansCells
  18. Mazumdar M, Adhikary A, Chakraborty S, Mukherjee S, Manna A, Saha S, Mohanty S, Dutta A, Bhattacharjee P, Ray P, Chattopadhyay S, Banerjee S, Chakraborty J, Ray AK, Sa G, Das T. Targeting RET to induce medullary thyroid cancer cell apoptosis: an antagonistic interplay between PI3K/Akt and p38MAPK/caspase-8 pathways. Apoptosis. 2013 May; 18(5):589-604. PMID: 23329180.
    Citations: 10     Fields:    Translation:HumansCells
  19. Ghosh S, Adhikary A, Chakraborty S, Nandi P, Mohanty S, Chakraborty S, Bhattacharjee P, Mukherjee S, Putatunda S, Chakraborty S, Chakraborty A, Sa G, Das T, Sen PC. Nifetepimine, a dihydropyrimidone, ensures CD4+ T cell survival in a tumor microenvironment by maneuvering sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA). J Biol Chem. 2012 Sep 21; 287(39):32881-96. PMID: 22851172.
    Citations: 10     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  20. Mohanty S, Adhikary A, Chakrabarty S, Sa G, Das T. Operation 'p53 Hunt' to combat cancer: theaflavins in action. Front Biosci (Schol Ed). 2012 01 01; 4(1):300-20. PMID: 22202062.
    Citations: 1     Fields:    Translation:HumansAnimals
  21. Saha B, Adhikary A, Ray P, Saha S, Chakraborty S, Mohanty S, Das K, Mukherjee S, Mazumdar M, Lahiri L, Hossain DM, Sa G, Das T. Restoration of tumor suppressor p53 by differentially regulating pro- and anti-p53 networks in HPV-18-infected cervical cancer cells. Oncogene. 2012 Jan 12; 31(2):173-86. PMID: 21765464.
    Citations: 13     Fields:    Translation:HumansCells
  22. Adhikary A, Mohanty S, Lahiry L, Hossain DM, Chakraborty S, Das T. Theaflavins retard human breast cancer cell migration by inhibiting NF-kappaB via p53-ROS cross-talk. FEBS Lett. 2010 Jan 04; 584(1):7-14. PMID: 19883646.
    Citations: 32     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.