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Longle Ma, Ph.D.

Title
Institution
Department
Address

Biography
Nankai University, Tianjin, ChinaBachelor of Science06/2010Chemistry
Rutgers University, New Brunswick, NJPh.D.06/2015Organic Chemistry

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ma L, Cao X, Wang H, Lu K, Wang Y, Tu C, Dai Y, Meng Y, Li Y, Yu P, Man S, Diao A. Discovery of Myricetin as a Potent Inhibitor of Human Flap Endonuclease 1, Which Potentially Can Be Used as Sensitizing Agent against HT-29 Human Colon Cancer Cells. J Agric Food Chem. 2019 Feb 13; 67(6):1656-1665. PMID: 30694659.
    Citations:    Fields:    
  2. Deng X, Hatori A, Chen Z, Kumata K, Shao T, Zhang X, Yamasaki T, Hu K, Yu Q, Ma L, Wang G, Wang L, Shao Y, Josephson L, Sun S, Zhang MR, Liang S. Synthesis and Preliminary Evaluation of 11 C-Labeled VU0467485/AZ13713945 and Its Analogues for Imaging Muscarinic Acetylcholine Receptor Subtype 4. ChemMedChem. 2019 Feb 05; 14(3):303-309. PMID: 30589226.
    Citations:    Fields:    
  3. Cui J, Man S, Cui N, Yang L, Guo Q, Ma L, Gao W. The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase-mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis. Cell Prolif. 2019 Jan; 52(1):e12520. PMID: 30338602.
    Citations:    Fields:    
  4. Gao F, Yang H, Lu T, Chen Z, Ma L, Xu Z, Schaffer P, Lu G. Design, synthesis and anti-mycobacterial activity evaluation of benzofuran-isatin hybrids. Eur J Med Chem. 2018 Nov 05; 159:277-281. PMID: 30296686.
    Citations:    Fields:    Translation:Cells
  5. Ma L, Meng Y, Tu C, Cao X, Wang H, Li Y, Man S, Zhou J, Li M, Liu Z, Su Y. A cardiac glycoside HTF-1 isolated from Helleborus thibetanus Franch displays potent in vitro anti-cancer activity via caspase-9, MAPK and PI3K-Akt-mTOR pathways. Eur J Med Chem. 2018 Oct 05; 158:743-752. PMID: 30245398.
    Citations:    Fields:    Translation:HumansAnimalsCells
  6. Gao F, Wang P, Yang H, Miao Q, Ma L, Lu G. Recent developments of quinolone-based derivatives and their activities against Escherichia coli. Eur J Med Chem. 2018 Sep 05; 157:1223-1248. PMID: 30193220.
    Citations:    Fields:    Translation:HumansAnimalsCells
  7. Yu B, Ma L, Jin J, Jiang F, Zhou G, Yan K, Liu Y. Mitochondrial toxicity induced by a thiourea gold(i) complex: mitochondrial permeability transition and respiratory deficit. Toxicol Res (Camb). 2018 Nov 01; 7(6):1081-1090. PMID: 30542602.
    Citations:    
  8. Chen Z, Mori W, Zhang X, Yamasaki T, Dunn PJ, Zhang G, Fu H, Shao T, Zhang Y, Hatori A, Ma L, Fujinaga M, Xie L, Deng X, Li H, Yu Q, Rong J, Josephson L, Ma JA, Shao Y, Tomita S, Zhang MR, Liang SH. Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging ?8-dependent transmembrane AMPA receptor regulatory protein. Eur J Med Chem. 2018 Sep 05; 157:898-908. PMID: 30145376.
    Citations:    Fields:    Translation:HumansCells
  9. Ma L, Bi KD, Fan YM, Jiang ZY, Zhang XY, Zhang JW, Zhao J, Jiang FL, Dong JX. In vitro modulation of mercury-induced rat liver mitochondria dysfunction. Toxicol Res (Camb). 2018 Nov 01; 7(6):1135-1143. PMID: 30510683.
    Citations:    
  10. Ma L, Sun N, Meng Y, Tu C, Cao X, Wei Y, Chu L, Diao A. Harnessing the affinity of magnetic nanoparticles toward dye-labeled DNA and developing it as an universal aptasensor revealed by lipopolysaccharide detection. Anal Chim Acta. 2018 Dec 07; 1036:107-114. PMID: 30253820.
    Citations:    Fields:    Translation:Cells
  11. Yao J, Man S, Dong H, Yang L, Ma L, Gao W. Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib. J Steroid Biochem Mol Biol. 2018 Oct; 183:159-166. PMID: 29932973.
    Citations:    Fields:    
  12. Ma L, Dong JX, Fu WR, Li XY, Chen J, Liu Y. Mitochondrial morphology and function impaired by dimethyl sulfoxide and dimethyl Formamide. J Bioenerg Biomembr. 2018 08; 50(4):297-305. PMID: 29770896.
    Citations:    Fields:    
  13. Man S, Zhang L, Cui J, Yang L, Ma L, Gao W. Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells. Cell Prolif. 2018 Aug; 51(4):e12458. PMID: 29608021.
    Citations:    Fields:    Translation:HumansCells
  14. Cheng R, Mori W, Ma L, Alhouayek M, Hatori A, Zhang Y, Ogasawara D, Yuan G, Chen Z, Zhang X, Shi H, Yamasaki T, Xie L, Kumata K, Fujinaga M, Nagai Y, Minamimoto T, Svensson M, Wang L, Du Y, Ondrechen MJ, Vasdev N, Cravatt BF, Fowler C, Zhang MR, Liang SH. In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies. J Med Chem. 2018 03 22; 61(6):2278-2291. PMID: 29481079.
    Citations:    Fields:    
  15. Li ZQ, Ma L, Yin Q, Cai XM, Luo ZX, Bian L, Xin ZJ, He P, Chen ZM. Gene Identification of Pheromone Gland Genes Involved in Type II Sex Pheromone Biosynthesis and Transportation in Female Tea Pest Ectropis grisescens. G3 (Bethesda). 2018 03 02; 8(3):899-908. PMID: 29317471.
    Citations:    Fields:    Translation:AnimalsCells
  16. Ma L, Sun N, Zhang J, Tu C, Cao X, Duan D, Diao A, Man S. Polyethylenimine-coated Fe3O4 nanoparticles effectively quench fluorescent DNA, which can be developed as a novel platform for protein detection. Nanoscale. 2017 Nov 23; 9(45):17699-17703. PMID: 29130087.
    Citations:    Fields:    Translation:HumansCells
  17. Man S, Chai H, Cui J, Yao J, Ma L, Gao W. Antitumor and anti-metastatic mechanisms of Rhizoma paridis saponins in Lewis mice. Environ Toxicol. 2018 Feb; 33(2):149-155. PMID: 29148169.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  18. Ma L, Liu JY, Dong JX, Xiao Q, Zhao J, Jiang FL. Toxicity of Pb2+ on rat liver mitochondria induced by oxidative stress and mitochondrial permeability transition. Toxicol Res (Camb). 2017 Nov 01; 6(6):822-830. PMID: 30090545.
    Citations:    
  19. Liu Z, Huo X, Zhao S, Yang J, Shi W, Jing L, Li W, Li Y, Ma L, Gao Y, Diao A. Low density lipoprotein receptor class A domain containing 4 (LDLRAD4) promotes tumorigenesis of hepatic cancer cells. Exp Cell Res. 2017 11 15; 360(2):189-198. PMID: 28888937.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  20. Krishnan HS, Ma L, Vasdev N, Liang SH. 18 F-Labeling of Sensitive Biomolecules for Positron Emission Tomography. Chemistry. 2017 Nov 07; 23(62):15553-15577. PMID: 28704575.
    Citations:    Fields:    Translation:Humans
  21. Liu W, Ma L, Abuduwaili J, Li Y. Distribution, source analysis, and ecological risk assessment of polycyclic aromatic hydrocarbons in the typical topsoil of the Issyk-Kul Lake Basin. Environ Monit Assess. 2017 Aug; 189(8):398. PMID: 28718094.
    Citations: 2     Fields:    Translation:HumansAnimalsPHPublic Health
  22. Xiang X, Wu C, Zhang BR, Gao T, Zhao J, Ma L, Jiang FL, Liu Y. The relationship between the length of surface ligand and effects of CdTe quantum dots on the physiological functions of isolated mitochondria. Chemosphere. 2017 Oct; 184:1108-1116. PMID: 28672691.
    Citations: 3     Fields:    Translation:Cells
  23. Zhang X, Kumata K, Yamasaki T, Cheng R, Hatori A, Ma L, Zhang Y, Xie L, Wang L, Kang HJ, Sheffler DJ, Cosford NDP, Zhang MR, Liang SH. Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[11C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 2. ACS Chem Neurosci. 2017 09 20; 8(9):1937-1948. PMID: 28565908.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  24. Ma L, Placzek MS, Hooker JM, Vasdev N, Liang SH. [11C]Cyanation of arylboronic acids in aqueous solutions. Chem Commun (Camb). 2017 Jun 21; 53(49):6597-6600. PMID: 28580477.
    Citations: 2     Fields:    
  25. Xu X, Liang H, Zhang X, Ma L, Zhao C, Sun L. Intraoperative neurophysiological monitoring to protect the facial nerve during microsurgery for large vestibular schwannomas. Neuro Endocrinol Lett. 2017 May; 38(2):91-97. PMID: 28650602.
    Citations:    Fields:    Translation:Humans
  26. Qiu P, Sun J, Man S, Yang H, Ma L, Yu P, Gao W. Curcumin Attenuates N-Nitrosodiethylamine-Induced Liver Injury in Mice by Utilizing the Method of Metabonomics. J Agric Food Chem. 2017 Mar 08; 65(9):2000-2007. PMID: 28198625.
    Citations: 4     Fields:    Translation:HumansAnimals
  27. Zheng J, Cheng R, Lin JH, Yu DH, Ma L, Jia L, Zhang L, Wang L, Xiao JC, Liang SH. An Unconventional Mechanistic Insight into SCF3 Formation from Difluorocarbene: Preparation of 18 F-Labeled a-SCF3 Carbonyl Compounds. Angew Chem Int Ed Engl. 2017 03 13; 56(12):3196-3200. PMID: 28194833.
    Citations: 1     Fields:    
  28. Ma L, Liu H, Qin P, Hu C, Man S, Li Y, Liu Z, Liu Z, Diao A. Saponin fraction isolated from Conyza blinii H.Lév. demonstrates strong anti-cancer activity that is due to its NF-?B inhibition. Biochem Biophys Res Commun. 2017 01 29; 483(1):779-785. PMID: 27979664.
    Citations:    Fields:    Translation:HumansAnimalsCells
  29. Ma L, Paul A, Breugst M, Seidel D. Redox-Neutral Aromatization of Cyclic Amines: Mechanistic Insights and Harnessing of Reactive Intermediates for Amine a- and ß-C-H Functionalization. Chemistry. 2016 Dec 12; 22(50):18179-18189. PMID: 27712000.
    Citations: 4     Fields:    
  30. Wang L, Mori W, Cheng R, Yui J, Hatori A, Ma L, Zhang Y, Rotstein BH, Fujinaga M, Shimoda Y, Yamasaki T, Xie L, Nagai Y, Minamimoto T, Higuchi M, Vasdev N, Zhang MR, Liang SH. Synthesis and Preclinical Evaluation of Sulfonamido-based [(11)C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase. Theranostics. 2016; 6(8):1145-59. PMID: 27279908.
    Citations: 3     Fields:    Translation:Animals
  31. He Q, Li Y, Ma L, Ji X, Li G. Application of FLEEOX Preoperative Chemotherapy via Intra-arterial and Intravenous Administration in Treatment of Unresectable Locally Advanced Gastric Cancer. J Gastrointest Surg. 2016 08; 20(8):1421-7. PMID: 27114248.
    Citations:    Fields:    Translation:Humans
  32. He Q, Ma L, Li Y, Li G. A pilot study of an individualized comprehensive treatment for advanced gastric cancer with para-aortic lymph node metastasis. BMC Gastroenterol. 2016 Jan 18; 16:8. PMID: 26782354.
    Citations: 3     Fields:    Translation:Humans
  33. Ma L, Wu G, Li Y, Qin P, Meng L, Liu H, Li Y, Diao A. A reversible metal ion fueled DNA three-way junction molecular device for "turn-on and -off" fluorescence detection of mercury ions (II) and biothiols respectively with high selectivity and sensitivity. Nanoscale. 2015 Nov 21; 7(43):18044-8. PMID: 26487480.
    Citations:    Fields:    
  34. Ma L, Seidel D. Intramolecular Redox-Mannich Reactions: Facile Access to the Tetrahydroprotoberberine Core. Chemistry. 2015 Sep 07; 21(37):12908-13. PMID: 26220197.
    Citations: 7     Fields:    Translation:Cells
  35. Miller N, Feng Z, Edens BM, Yang B, Shi H, Sze CC, Hong BT, Su SC, Cantu JA, Topczewski J, Crawford TO, Ko CP, Sumner CJ, Ma L, Ma YC. Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy. J Neurosci. 2015 Apr 15; 35(15):6038-50. PMID: 25878277.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  36. Ma L, Bartholome A, Tong MH, Qin Z, Yu Y, Shepherd T, Kyeremeh K, Deng H, O'Hagan D. Identification of a fluorometabolite from Streptomyces sp. MA37: (2R3S4S)-5-fluoro-2,3,4-trihydroxypentanoic acid. Chem Sci. 2015 Feb 01; 6(2):1414-1419. PMID: 29861965.
    Citations:    
  37. Ma L, Liu J. The protective activity of Conyza blinii saponin against acute gastric ulcer induced by ethanol. J Ethnopharmacol. 2014 Dec 02; 158 Pt A:358-63. PMID: 25446589.
    Citations: 1     Fields:    Translation:Animals
  38. Shen B, Wang W, Ma L, Wang S, Ding L, Chen Z, Sao Y, Shen H, Wei Z, Zhang W. RETRACTED: Sulforaphane restores oxidative stress induced by di-N-butylphthalate in testicular Leydig cells with low basal reactive oxygen species levels. Urology. 2014 10; 84(4):850-6. PMID: 25106942.
    Citations:    Fields:    Translation:AnimalsCells
  39. Ma L, Chen W, Seidel D. Redox-neutral a-cyanation of amines. J Am Chem Soc. 2012 Sep 19; 134(37):15305-8. PMID: 22963652.
    Citations: 20     Fields:    Translation:Cells
  40. Das D, Richers MT, Ma L, Seidel D. The decarboxylative Strecker reaction. Org Lett. 2011 Dec 16; 13(24):6584-7. PMID: 22087753.
    Citations: 10     Fields:    Translation:Cells
  41. Yao Z, Yin P, Su D, Peng Z, Zhou L, Ma L, Guo W, Ma L, Xu G, Shi J, Jiao B. Serum metabolic profiling and features of papillary thyroid carcinoma and nodular goiter. Mol Biosyst. 2011 Sep; 7(9):2608-14. PMID: 21713270.
    Citations: 6     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.