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Davide Seruggia, Ph.D.

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CNB-CSIC, Madrid, SpainPhD12/2014Molecular Biology

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Seruggia D, Josa S, Fernández A, Montoliu L. The structure and function of the mouse tyrosinase locus. Pigment Cell Melanoma Res. 2021 Mar; 34(2):212-221. PMID: 33098271.
    Citations:    Fields:    
  2. Seruggia D, Fernández A, Cantero M, Fernández-Miñán A, Gomez-Skarmeta JL, Pelczar P, Montoliu L. Boundary sequences flanking the mouse tyrosinase locus ensure faithful pattern of gene expression. Sci Rep. 2020 09 23; 10(1):15494. PMID: 32968154.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Cai W, Huang J, Zhu Q, Li BE, Seruggia D, Zhou P, Nguyen M, Fujiwara Y, Xie H, Yang Z, Hong D, Ren P, Xu J, Pu WT, Yuan GC, Orkin SH. Enhancer dependence of cell-type-specific gene expression increases with developmental age. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21450-21458. PMID: 32817427.
    Citations: 1     Fields:    Translation:AnimalsCells
  4. Manieri E, Folgueira C, Rodríguez ME, Leiva-Vega L, Esteban-Lafuente L, Chen C, Cubero FJ, Barrett T, Cavanagh-Kyros J, Seruggia D, Rosell A, Sanchez-Cabo F, Gómez MJ, Monte MJ, G Marin JJ, Davis RJ, Mora A, Sabio G. JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma. Proc Natl Acad Sci U S A. 2020 07 14; 117(28):16492-16499. PMID: 32601222.
    Citations: 2     Fields:    Translation:HumansAnimals
  5. Debruyne DN, Dries R, Sengupta S, Seruggia D, Gao Y, Sharma B, Huang H, Moreau L, McLane M, Day DS, Marco E, Chen T, Gray NS, Wong KK, Orkin SH, Yuan GC, Young RA, George RE. BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells. Nature. 2019 08; 572(7771):676-680. PMID: 31391581.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  6. Sher F, Hossain M, Seruggia D, Schoonenberg VAC, Yao Q, Cifani P, Dassama LMK, Cole MA, Ren C, Vinjamur DS, Macias-Trevino C, Luk K, McGuckin C, Schupp PG, Canver MC, Kurita R, Nakamura Y, Fujiwara Y, Wolfe SA, Pinello L, Maeda T, Kentsis A, Orkin SH, Bauer DE. Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis. Nat Genet. 2019 07; 51(7):1149-1159. PMID: 31253978.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  7. Di Pilato M, Kim EY, Cadilha BL, Prüßmann JN, Nasrallah MN, Seruggia D, Usmani SM, Misale S, Zappulli V, Carrizosa E, Mani V, Ligorio M, Warner RD, Medoff BD, Marangoni F, Villani AC, Mempel TR. Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. Nature. 2019 06; 570(7759):112-116. PMID: 31092922.
    Citations: 36     Fields:    Translation:AnimalsCells
  8. Seruggia D, Oti M, Tripathi P, Canver MC, LeBlanc L, Di Giammartino DC, Bullen MJ, Nefzger CM, Sun YBY, Farouni R, Polo JM, Pinello L, Apostolou E, Kim J, Orkin SH, Das PP. TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network. Mol Cell. 2019 06 20; 74(6):1148-1163.e7. PMID: 31005419.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  9. LeBlanc L, Lee BK, Yu AC, Kim M, Kambhampati AV, Dupont SM, Seruggia D, Ryu BU, Orkin SH, Kim J. Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation. Elife. 2018 12 18; 7. PMID: 30561326.
    Citations: 8     Fields:    Translation:AnimalsCells
  10. Josa S, Seruggia D, Fernández A, Montoliu L. Concepts and tools for gene editing. Reprod Fertil Dev. 2016 Jan; 29(1):1-7. PMID: 28278788.
    Citations: 2     Fields:    
  11. Wang J, Vicente-García C, Seruggia D, Moltó E, Fernandez-Miñán A, Neto A, Lee E, Gómez-Skarmeta JL, Montoliu L, Lunyak VV, Jordan IK. MIR retrotransposon sequences provide insulators to the human genome. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):E4428-37. PMID: 26216945.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  12. Seruggia D, Fernández A, Cantero M, Pelczar P, Montoliu L. Functional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR-Cas9-mediated mutagenesis. Nucleic Acids Res. 2015 May 26; 43(10):4855-67. PMID: 25897126.
    Citations: 27     Fields:    Translation:AnimalsCells
  13. Harms DW, Quadros RM, Seruggia D, Ohtsuka M, Takahashi G, Montoliu L, Gurumurthy CB. Mouse Genome Editing Using the CRISPR/Cas System. Curr Protoc Hum Genet. 2014 Oct 01; 83:15.7.1-27. PMID: 25271839.
    Citations: 31     Fields:    Translation:AnimalsCells
  14. Seruggia D, Montoliu L. The new CRISPR-Cas system: RNA-guided genome engineering to efficiently produce any desired genetic alteration in animals. Transgenic Res. 2014 Oct; 23(5):707-16. PMID: 25092533.
    Citations: 20     Fields:    Translation:AnimalsCells
  15. Court F, Camprubi C, Garcia CV, Guillaumet-Adkins A, Sparago A, Seruggia D, Sandoval J, Esteller M, Martin-Trujillo A, Riccio A, Montoliu L, Monk D. The PEG13-DMR and brain-specific enhancers dictate imprinted expression within the 8q24 intellectual disability risk locus. Epigenetics Chromatin. 2014 Mar 25; 7(1):5. PMID: 24667089.
    Citations: 17     Fields:    
  16. Hermann M, Stillhard P, Wildner H, Seruggia D, Kapp V, Sánchez-Iranzo H, Mercader N, Montoliu L, Zeilhofer HU, Pelczar P. Binary recombinase systems for high-resolution conditional mutagenesis. Nucleic Acids Res. 2014 Apr; 42(6):3894-907. PMID: 24413561.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  17. Cassina V, Seruggia D, Beretta GL, Salerno D, Brogioli D, Manzini S, Zunino F, Mantegazza F. Atomic force microscopy study of DNA conformation in the presence of drugs. Eur Biophys J. 2011 Jan; 40(1):59-68. PMID: 20882274.
    Citations: 13     Fields:    Translation:Cells
  18. Rupprecht S, Hagedorn C, Seruggia D, Magnusson T, Wagner E, Ogris M, Lipps HJ. Controlled removal of a nonviral episomal vector from transfected cells. Gene. 2010 Oct 15; 466(1-2):36-42. PMID: 20621169.
    Citations: 6     Fields:    Translation:AnimalsCells
  19. Salerno D, Brogioli D, Cassina V, Turchi D, Beretta GL, Seruggia D, Ziano R, Zunino F, Mantegazza F. Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs. Nucleic Acids Res. 2010 Nov; 38(20):7089-99. PMID: 20601682.
    Citations: 11     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.