Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Jonathan B. Cohen, Ph.D.

Co-Author

This page shows the publications co-authored by Jonathan Cohen and Selwyn Jayakar.
Connection Strength

4.466
  1. Jayakar SS, Chiara DC, Zhou X, Wu B, Bruzik KS, Miller KW, Cohen JB. Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABAA) receptors. J Biol Chem. 2020 Aug 14; 295(33):11495-11512.
    View in: PubMed
    Score: 0.976
  2. Jayakar SS, Zhou X, Chiara DC, Jarava-Barrera C, Savechenkov PY, Bruzik KS, Tortosa M, Miller KW, Cohen JB. Identifying Drugs that Bind Selectively to Intersubunit General Anesthetic Sites in the a1ß3?2 GABAAR Transmembrane Domain. Mol Pharmacol. 2019 06; 95(6):615-628.
    View in: PubMed
    Score: 0.899
  3. Jayakar SS, Zhou X, Savechenkov PY, Chiara DC, Desai R, Bruzik KS, Miller KW, Cohen JB. Positive and Negative Allosteric Modulation of an a1ß3?2 ?-Aminobutyric Acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the ?+-ß- Interface. J Biol Chem. 2015 Sep 18; 290(38):23432-46.
    View in: PubMed
    Score: 0.696
  4. Jayakar SS, Zhou X, Chiara DC, Dostalova Z, Savechenkov PY, Bruzik KS, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Multiple propofol-binding sites in a ?-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog. J Biol Chem. 2014 Oct 03; 289(40):27456-68.
    View in: PubMed
    Score: 0.650
  5. Jayakar SS, Dailey WP, Eckenhoff RG, Cohen JB. Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog. J Biol Chem. 2013 Mar 01; 288(9):6178-89.
    View in: PubMed
    Score: 0.583
  6. Hamouda AK, Jayakar SS, Chiara DC, Cohen JB. Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites! J Mol Neurosci. 2014 Jul; 53(3):480-6.
    View in: PubMed
    Score: 0.154
  7. Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human a1ß3?2 ?-aminobutyric acid type A (GABAA) receptor. J Biol Chem. 2013 Jul 05; 288(27):19343-57.
    View in: PubMed
    Score: 0.149
  8. Chiara DC, Dostalova Z, Jayakar SS, Zhou X, Miller KW, Cohen JB. Mapping general anesthetic binding site(s) in human a1ß3 ?-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue. Biochemistry. 2012 Jan 31; 51(4):836-47.
    View in: PubMed
    Score: 0.136
  9. McGrath M, Hoyt H, Pence A, Jayakar SS, Zhou X, Forman SA, Cohen JB, Miller KW, Raines DE. Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology. 2020 09; 133(3):583-594.
    View in: PubMed
    Score: 0.062
  10. Wu B, Jayakar SS, Zhou X, Titterton K, Chiara DC, Szabo AL, Savechenkov PY, Kent DE, Cohen JB, Forman SA, Miller KW, Bruzik KS. Inhibitable photolabeling by neurosteroid diazirine analog in the ß3-Subunit of human hetereopentameric type A GABA receptors. Eur J Med Chem. 2019 Jan 15; 162:810-824.
    View in: PubMed
    Score: 0.055
  11. McGrath M, Yu Z, Jayakar SS, Ma C, Tolia M, Zhou X, Miller KW, Cohen JB, Raines DE. Etomidate and Etomidate Analog Binding and Positive Modulation of ?-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. Anesthesiology. 2018 11; 129(5):959-969.
    View in: PubMed
    Score: 0.055
  12. Ma C, Pejo E, McGrath M, Jayakar SS, Zhou X, Miller KW, Cohen JB, Raines DE. Competitive Antagonism of Anesthetic Action at the ?-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy. Anesthesiology. 2017 11; 127(5):824-837.
    View in: PubMed
    Score: 0.051
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.