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David Mengel

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mengel D, Liu W, Glynn RJ, Selkoe DJ, Strydom A, Lai F, Rosas HD, Torres A, Patsiogiannis V, Skotko B, Walsh DM. Dynamics of plasma biomarkers in Down syndrome: the relative levels of Aß42 decrease with age, whereas NT1 tau and NfL increase. Alzheimers Res Ther. 2020 Mar 19; 12(1):27. PMID: 32192521.
    Citations:    
  2. Cha DJ, Mengel D, Mustapic M, Liu W, Selkoe DJ, Kapogiannis D, Galasko D, Rissman RA, Bennett DA, Walsh DM. miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer's Patients. Front Neurosci. 2019; 13:1208. PMID: 31849573.
    Citations:    
  3. Mengel D, Liu L, Yamamoto R, Zülow S, Deuschl C, Hermann DM, Zerr I, Selkoe DJ, Dodel R. A novel V272D presenilin mutation associated with logopenia, disorientation, and apraxia in an autosomal-dominant Alzheimer's disease family. Neurobiol Aging. 2020 01; 85:154.e5-154.e7. PMID: 31500908.
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  4. Yang T, Dang Y, Ostaszewski B, Mengel D, Steffen V, Rabe C, Bittner T, Walsh DM, Selkoe DJ. Target engagement in an alzheimer trial: Crenezumab lowers amyloid ß oligomers in cerebrospinal fluid. Ann Neurol. 2019 08; 86(2):215-224. PMID: 31168802.
    Citations:    
  5. Mengel D, Dodel R, Tackenberg B. Reply. Muscle Nerve. 2019 03; 59(3):E23. PMID: 30615220.
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  6. Mengel D, Hong W, Corbett GT, Liu W, DeSousa A, Solforosi L, Fang C, Frosch MP, Collinge J, Harris DA, Walsh DM. PrP-grafted antibodies bind certain amyloid ß-protein aggregates, but do not prevent toxicity. Brain Res. 2019 05 01; 1710:125-135. PMID: 30593771.
    Citations:    Fields:    
  7. Purro SA, Farrow MA, Linehan J, Nazari T, Thomas DX, Chen Z, Mengel D, Saito T, Saido T, Rudge P, Brandner S, Walsh DM, Collinge J. Transmission of amyloid-ß protein pathology from cadaveric pituitary growth hormone. Nature. 2018 12; 564(7736):415-419. PMID: 30546139.
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  8. Chen Z, Mengel D, Keshavan A, Rissman RA, Billinton A, Perkinton M, Percival-Alwyn J, Schultz A, Properzi M, Johnson K, Selkoe DJ, Sperling RA, Patel P, Zetterberg H, Galasko D, Schott JM, Walsh DM. Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease. Alzheimers Dement. 2019 03; 15(3):487-496. PMID: 30419228.
    Citations:    Fields:    
  9. Mengel D, Fraune L, Sommer N, Stettner M, Reese JP, Dams J, Glynn RJ, Balzer-Geldsetzer M, Dodel R, Tackenberg B. Costs of illness in chronic inflammatory demyelinating polyneuropathy in Germany. Muscle Nerve. 2018 11; 58(5):681-687. PMID: 30073683.
    Citations:    
  10. Albus A, Gold M, Bach JP, Burg-Roderfeld M, Jördens M, Kirchhein Y, Kronimus Y, Mengel D, Zerr I, Dodel R. Extending the functional characteristics of naturally occurring autoantibodies against ß-Amyloid, Prion Protein and a-Synuclein. PLoS One. 2018; 13(8):e0202954. PMID: 30157279.
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  11. Mengel D, Librizzi D, Schoser B, Gläser D, Clemen CS, Dodel R, Schröder R. [Inclusion Body Myopathy, Paget's Disease, and Fronto-temporal Dementia: a VCP-related Multi-systemic Proteinopathy]. Fortschr Neurol Psychiatr. 2018 07; 86(7):434-438. PMID: 30029282.
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  12. Guix FX, Corbett GT, Cha DJ, Mustapic M, Liu W, Mengel D, Chen Z, Aikawa E, Young-Pearse T, Kapogiannis D, Selkoe DJ, Walsh DM. Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles. Int J Mol Sci. 2018 Feb 27; 19(3). PMID: 29495441.
    Citations: 1     Fields:    Translation:HumansCells
  13. Kronimus Y, Albus A, Balzer-Geldsetzer M, Straub S, Semler E, Otto M, Klotsche J, Dodel R, Mengel D. Naturally Occurring Autoantibodies against Tau Protein Are Reduced in Parkinson's Disease Dementia. PLoS One. 2016; 11(11):e0164953. PMID: 27802290.
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  14. Mengel D, Dams J, Ziemek J, Becker J, Balzer-Geldsetzer M, Hilker R, Baudrexel S, Kalbe E, Schmidt N, Witt K, Liepelt-Scarfone I, Gräber S, Petrelli A, Neuser P, Schulte C, Linse K, Storch A, Wittchen HU, Riedel O, Mollenhauer B, Ebentheuer J, Trenkwalder C, Klockgether T, Spottke A, Wüllner U, Schulz JB, Reetz K, Heber IA, Ramirez A, Dodel R. Apolipoprotein E e4 does not affect cognitive performance in patients with Parkinson's disease. Parkinsonism Relat Disord. 2016 08; 29:112-6. PMID: 27321987.
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  15. Mengel D, Thelen M, Balzer-Geldsetzer M, Söling C, Bach JP, Schaeffer E, Herold C, Becker T, Liepelt I, Becker J, Riedel-Heller S, Scherer M, Jessen F, Maier W, Dodel R, Ramirez A. TREM2 rare variant p.R47H is not associated with Parkinson's disease. Parkinsonism Relat Disord. 2016 Feb; 23:109-11. PMID: 26651418.
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  16. Gold M, Koczulla AR, Mengel D, Koepke J, Dodel R, Dontcheva G, Habib P, Bach JP. Reduction of glutamate-induced excitotoxicity in murine primary neurons involving calpain inhibition. J Neurol Sci. 2015 Dec 15; 359(1-2):356-62. PMID: 26671142.
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  17. Bach JP, Gold M, Mengel D, Hattesohl A, Lubbe D, Schmid S, Tackenberg B, Rieke J, Maddula S, Baumbach JI, Nell C, Boeselt T, Michelis J, Alferink J, Heneka M, Oertel W, Jessen F, Janciauskiene S, Vogelmeier C, Dodel R, Koczulla AR. Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease. PLoS One. 2015; 10(7):e0132227. PMID: 26168044.
    Citations: 3     Fields:    Translation:HumansAnimals
  18. Gold M, Dolga AM, Koepke J, Mengel D, Culmsee C, Dodel R, Koczulla AR, Bach JP. a1-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-ß-induced toxicity. J Neuroinflammation. 2014 Sep 23; 11:165. PMID: 25245568.
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  19. Steiner L, Gold M, Mengel D, Dodel R, Bach JP. The endogenous a7 nicotinic acetylcholine receptor antagonist kynurenic acid modulates amyloid-ß-induced inflammation in BV-2 microglial cells. J Neurol Sci. 2014 Sep 15; 344(1-2):94-9. PMID: 25064444.
    Citations:    
  20. Gold M, Mengel D, Röskam S, Dodel R, Bach JP. Mechanisms of action of naturally occurring antibodies against ß-amyloid on microglia. J Neuroinflammation. 2013 Jan 14; 10:5. PMID: 23317003.
    Citations:    
  21. Bach JP, Mengel D, Wahle T, Kautz A, Balzer-Geldsetzer M, Al-Abed Y, Dodel R, Bacher M. The role of CNI-1493 in the function of primary microglia with respect to amyloid-ß. J Alzheimers Dis. 2011; 26(1):69-80. PMID: 21593565.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.