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David Eddie, Ph.D.

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Biography
Columbia University, New York, NYB.A.05/2010Psychology / Neuroscience
Rutgers University, New Brunswick, NJM.S.10/2013Clinical Psychology
Rutgers University, New Brunswick, NJPh.D.10/2016Clinical Psychology
Massachusetts General Hospital, Harvard Medical School, Boston, MAResidency06/2016Clinical Psychology
Massachusetts General Hospital, Harvard Medical School, Boston, MAPost-doctoral fellowship11/2018Clinical Psychology / Addiction Medicine

Overview
Dr. David Eddie is a research scientist at Massachusetts General Hospital’s Recovery Research Institute, Center for Addiction Medicine, and Center for Digital Mental Health, as well as a clinical psychologist in Massachusetts General Hospital’s Department of Psychiatry, and an assistant professor at Harvard Medical School.

His current NIAAA and NIDA funded research projects include: 1) A study seeking to better understand affective and psychophysiological factors that heighten addiction relapse risk with the aim of developing cutting-edge, mobile health interventions driven by wearable biosensors. 2) A randomized controlled trial of Heart Rate Variability Biofeedback for substance use disorder utilizing wearable biosensors. 3) A project assessing the efficacy of a novel mutual-help addiction recovery program based on physical activity known as The Phoenix.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21DA056468-01 (EDDIE, DAVID) Aug 1, 2022 - Jul 31, 2024
    NIH/NIDA
    A pilot study of ambulatory heart rate variability biofeedback for substance use disorder
    Role Description: Heart rate variability biofeedback (HRV BFB) is an exciting biobehavioral intervention involving rhythmic breathing at resonance frequency that stimulates cardiovascular regulatory systems to help individuals better regulate affect and bolster cognitive control. This intervention has already shown its potential as a substance use disorder (SUD) treatment tool, but practical limitations of its accessibility, labor intensiveness, and cost have previously prevented this intervention from going to scale. Second-generation, ambulatory HRV BFB technology, however, has overcome these limitations and now allows patients to practice HRV BFB in-the-moment when its needed most – we aim to pilot test this technology for the first time with individuals with SUD.
    Role: Principal Investigator
  2. L30AA026135-03 (EDDIE, DAVID) Jul 1, 2022 - Jun 30, 2024
    NIH/NIAAA
    Bringing real-time stress detection to scale: Development of a biosensor driven, stress detection classifier for smartwatches
    Role Description: Alcohol use disorder carries tremendous personal and societal costs, and in spite of best clinical efforts, this disorder is characterized by very high relapse rates following treatment. There is a pressing need for novel interventions that prevent alcohol use relapse, and help individuals achieve sustained remission. This study will develop the algorithms that will enable the biosensors embedded in commercially available smartwatches to detect stress in real time using physiological measures of autonomic arousal, which will ultimately be used to trigger smartphone relapse prevention apps to prompt patients with real-time coaching to mitigate alcohol use relapse risk.
    Role: Principal Investigator
  3. R24DA051988-02S1 (KELLY, JOHN) Aug 15, 2021 - Aug 14, 2023
    NIH/NIDA
    Investigating the clinical and public health utility of a novel physical activity-oriented addiction recovery support service
    Role Description: Opioid use disorder (OUD) is a highly treatable condition, especially with medications, yet most individuals typically need additional community support during and following treatment to enhance the chances of stable remission. The Phoenix is a novel addiction recovery community center (RCC) with a fast-growing membership of ~40,000 expanding rapidly across the United States providing free, peer-led physical activity classes to those in, or starting, recovery, through a national network of gyms, but despite its rapid growth, no systemic research has estimated The Phoenix’s clinical and public health potential as a bonafide recovery support service. This supplement fits within the scope of the recently funded NIDA R24 grant studying RCCs (R24 DA05198801) and will expand its impact by examining Phoenix’s real-world benefit, and determine who benefits and how.
    Role: Co-Investigator
  4. K12DA043490-03 (EDDIE, DAVID) Jul 1, 2020 - Jun 30, 2022
    NIH/NIDA
    Investigating the clinical and public health utility of a novel physical activity-oriented addiction recovery support service
    Role Description: The program of research is to use mixed methods to assess the acceptability and utility of a best-in-class substance use disorder recovery support app in primary care medical clinics. A secondary goal of this research is to leverage data collected to build a relapse risk classifier algorithm that can portend substance use lapses in real-time. This algorithm, which will ultimately be integrated into mHealth relapse prevention apps, will significantly benefit the field, as currently no such algorithm is publicly available. This research will form the basis for future randomized controlled trials and implementation studies.
    Role: Principal Investigator
  5. L30AA026135-02 (EDDIE, DAVID) Jul 1, 2020 - Jun 30, 2022
    NIH/NIAAA
    Bringing real-time stress detection to scale: Development of a biosensor driven, stress detection classifier for smartwatches
    Role Description: Alcohol use disorder carries tremendous personal and societal costs, and in spite of best clinical efforts, this disorder is characterized by very high relapse rates following treatment. There is a pressing need for novel interventions that prevent alcohol use relapse, and help individuals achieve sustained remission. This study will develop the algorithms that will enable the biosensors embedded in commercially available smartwatches to detect stress in real time using physiological measures of autonomic arousal, which will ultimately be used to trigger smartphone relapse prevention apps to prompt patients with real-time coaching to mitigate alcohol use relapse risk.
    Role: Principal Investigator
The clinical trials listed below are automatically derived from ClinicalTrials.gov and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
NCT Short Title Overall Status Start Completion

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.